Time filter

Source Type

Tallahassee, FL, United States

The Florida State University is a space-grant and sea-grant public research university located on a 474.5-acre campus in the state capital city of Tallahassee, Florida, United States. Florida State University is a research university with very high research activity as determined by the Carnegie Foundation. In 2014, U.S. News & World Report ranked Florida State as the forty-third best public university in the United States. The university comprises 16 separate colleges and more than 110 centers, facilities, labs and institutes that offer more than 300 programs of study, including professional programs. Florida State is home to Florida's only National Laboratory – the National High Magnetic Field Laboratory and is the birthplace of the commercially viable anti-cancer drug Taxol. Florida State University also operates The John & Mable Ringling Museum of Art, the State Art Museum of Florida and one of the largest museum/university complexes in the nation. Florida State University is accredited by the Southern Association of Colleges and Schools as a Level VI public institution.Florida State University was established in 1851 and is located on the oldest continuous site of higher education in the state of Florida. In 1905 Florida State earned Florida's first Rhodes Scholar. In 1935 Florida State University, at that time Florida State College for Women, was awarded the first chapter of Phi Beta Kappa in Florida and is among the ten percent of American universities to have earned a chapter of the national academic honor society. In 1977 Florida State University earned the first female Rhodes Scholar in Florida. In 2010 Florida State University was named a "Budget Ivy" university by the Fiske Guide to Getting into the Right College. In 2012 U.S. News & World Report ranked Florida State the most efficient National University in the United States. Florida State University is one of two Florida public universities to immediately qualify as a "preeminent university" by law under Florida Senate Bill 1076, signed by Governor Rick Scott in 2013.The Florida State University is home to nationally ranked programs in many academic areas, including law, business, engineering, medicine, social policy, film, music, theater, dance, visual art, political science, psychology, social work, and the science. Florida State University leads Florida in four of eight areas of external funding for the STEM disciplines . The university is also known for its undergraduate study abroad options: according to Uni in the USA, "the large numbers of students that study abroad nicely compliment the students that study here from abroad."Florida State University's intercollegiate sports teams, commonly known by their "Florida State Seminoles" nickname, compete in National Collegiate Athletic Association Division I and the Atlantic Coast Conference .Florida State University has won thirteen national athletic championships as well as multiple individual competitor NCAA championship awards. Wikipedia.

Schlenoff J.B.,Florida State University
Langmuir | Year: 2014

Coating surfaces with thin or thick films of zwitterionic material is an effective way to reduce or eliminate nonspecific adsorption to the solid/liquid interface. This review tracks the various approaches to zwitteration, such as monolayer assemblies and polymeric brush coatings, on micro-to macroscopic surfaces. A critical summary of the mechanisms responsible for antifouling shows how zwitterions are ideally suited to this task. © 2014 American Chemical Society. Source

Zhou H.-X.,Florida State University
Trends in Biochemical Sciences | Year: 2012

Association between signaling proteins and their cellular targets is generally thought to be highly specific (implicating a high association constant, K a) and, at the same time, transient or short-lived (corresponding to a high dissociation rate constant, k d). However, a combination of high K a and high k d would lead to a high association rate constant (k a = K ak d), which poses a problem because there is a limit to which k a can be increased, set by the diffusional approach to form the complex. In this Opinion article, I propose that having the signaling protein disordered before binding to the target provides a way out of this quandary. The intrinsic disorder of the signaling protein would decrease K a without sacrificing the specificity of the complex, and thus would allow k d to be increased to a range appropriate for signaling. © 2011 Elsevier Ltd. Source

Gilbert D.M.,Florida State University
Nature Reviews Genetics | Year: 2010

Mechanisms regulating where and when eukaryotic DNA replication initiates remain a mystery. Recently, genome-scale methods have been brought to bear on this problem. The identification of replication origins and their associated proteins in yeasts is a well-integrated investigative tool, but corresponding data sets from multicellular organisms are scarce. By contrast, standardized protocols for evaluating replication timing have generated informative data sets for most eukaryotic systems. Here, I summarize the genome-scale methods that are most frequently used to analyse replication in eukaryotes, the kinds of questions each method can address and the technical hurdles that must be overcome to gain a complete understanding of the nature of eukaryotic replication origins. © 2010 Macmillan Publishers Limited. All rights reserved. Source

Zhou H.-X.,Florida State University
Quarterly Reviews of Biophysics | Year: 2010

Some of the rate theories that are most useful for modeling biological processes are reviewed. By delving into some of the details and subtleties in the development of the theories, the review will hopefully help the reader gain a more than superficial perspective. Examples are presented to illustrate how rate theories can be used to generate insight at the microscopic level into biomolecular behaviors. An attempt is made to clear up a number of misconceptions in the literature regarding popular rate theories, including the appearance of Planck's constant in the transition-state theory and the Smoluchowski result as an upper limit for protein-protein and protein-DNA association rate constants. Future work in combining the implementation of rate theories through computer simulations with experimental probes of rate processes, and in modeling effects of intracellular environments so that theories can be used for generating rate constants for systems biology studies is particularly exciting. © 2010 Cambridge University Press. Source

Gilbert D.M.,Florida State University
Nature Structural and Molecular Biology | Year: 2012

The search for the holy replicator has been revitalized through ultradeep sequencing of small RNA-primed single-stranded DNA. Saturation sequencing provides an explanation for the lack of overlap in prior data sets, suggests that frequency of origin usage but not site selection is developmentally regulated, and uncovers a complex four-stranded DNA structure associated with most origins. © 2012 Nature America, Inc. All rights reserved. Source

Discover hidden collaborations