The Florida State University is a space-grant and sea-grant public research university located on a 474.5-acre campus in the state capital city of Tallahassee, Florida, United States. Florida State University is a research university with very high research activity as determined by the Carnegie Foundation. In 2014, U.S. News & World Report ranked Florida State as the forty-third best public university in the United States. The university comprises 16 separate colleges and more than 110 centers, facilities, labs and institutes that offer more than 300 programs of study, including professional programs. Florida State is home to Florida's only National Laboratory – the National High Magnetic Field Laboratory and is the birthplace of the commercially viable anti-cancer drug Taxol. Florida State University also operates The John & Mable Ringling Museum of Art, the State Art Museum of Florida and one of the largest museum/university complexes in the nation. Florida State University is accredited by the Southern Association of Colleges and Schools as a Level VI public institution.Florida State University was established in 1851 and is located on the oldest continuous site of higher education in the state of Florida. In 1905 Florida State earned Florida's first Rhodes Scholar. In 1935 Florida State University, at that time Florida State College for Women, was awarded the first chapter of Phi Beta Kappa in Florida and is among the ten percent of American universities to have earned a chapter of the national academic honor society. In 1977 Florida State University earned the first female Rhodes Scholar in Florida. In 2010 Florida State University was named a "Budget Ivy" university by the Fiske Guide to Getting into the Right College. In 2012 U.S. News & World Report ranked Florida State the most efficient National University in the United States. Florida State University is one of two Florida public universities to immediately qualify as a "preeminent university" by law under Florida Senate Bill 1076, signed by Governor Rick Scott in 2013.The Florida State University is home to nationally ranked programs in many academic areas, including law, business, engineering, medicine, social policy, film, music, theater, dance, visual art, political science, psychology, social work, and the science. Florida State University leads Florida in four of eight areas of external funding for the STEM disciplines . The university is also known for its undergraduate study abroad options: according to Uni in the USA, "the large numbers of students that study abroad nicely compliment the students that study here from abroad."Florida State University's intercollegiate sports teams, commonly known by their "Florida State Seminoles" nickname, compete in National Collegiate Athletic Association Division I and the Atlantic Coast Conference .Florida State University has won thirteen national athletic championships as well as multiple individual competitor NCAA championship awards. Wikipedia.
Zhou H.-X.,Florida State University
Trends in Biochemical Sciences | Year: 2012
Association between signaling proteins and their cellular targets is generally thought to be highly specific (implicating a high association constant, K a) and, at the same time, transient or short-lived (corresponding to a high dissociation rate constant, k d). However, a combination of high K a and high k d would lead to a high association rate constant (k a = K ak d), which poses a problem because there is a limit to which k a can be increased, set by the diffusional approach to form the complex. In this Opinion article, I propose that having the signaling protein disordered before binding to the target provides a way out of this quandary. The intrinsic disorder of the signaling protein would decrease K a without sacrificing the specificity of the complex, and thus would allow k d to be increased to a range appropriate for signaling. © 2011 Elsevier Ltd. Source
Jenkins A.,Florida State University
Physics Reports | Year: 2013
Physicists are very familiar with forced and parametric resonance, but usually not with self-oscillation, a property of certain dynamical systems that gives rise to a great variety of vibrations, both useful and destructive. In a self-oscillator, the driving force is controlled by the oscillation itself so that it acts in phase with the velocity, causing a negative damping that feeds energy into the vibration: no external rate needs to be adjusted to the resonant frequency. The famous collapse of the Tacoma Narrows bridge in 1940, often attributed by introductory physics texts to forced resonance, was actually a self-oscillation, as was the swaying of the London Millennium Footbridge in 2000. Clocks are self-oscillators, as are bowed and wind musical instruments. The heart is a "relaxation oscillator", i.e.,a non-sinusoidal self-oscillator whose period is determined by sudden, nonlinear switching at thresholds. We review the general criterion that determines whether a linear system can self-oscillate. We then describe the limiting cycles of the simplest nonlinear self-oscillators, as well as the ability of two or more coupled self-oscillators to become spontaneously synchronized ("entrained"). We characterize the operation of motors as self-oscillation and prove a theorem about their limit efficiency, of which Carnot's theorem for heat engines appears as a special case. We briefly discuss how self-oscillation applies to servomechanisms, Cepheid variable stars, lasers, and the macroeconomic business cycle, among other applications. Our emphasis throughout is on the energetics of self-oscillation, often neglected by the literature on nonlinear dynamical systems. © 2012 Elsevier B.V. Source
Florida State University | Date: 2015-01-22
An article comprising a polyelectrolyte complex comprising an interpenetrating network of at least one predominantly positively charged polyelectrolyte polymer and at least one predominantly negatively charged polyelectrolyte polymer, the polyelectrolyte complex further comprising a plurality of closed-shell pores, the plurality of pores having at least one average transverse dimension between about 100 nanometer and about 1000 micrometers.
Florida State University | Date: 2015-10-30
A method for extracting protein from a fat-containing sample is described comprising the steps of separating solidified fat and solid residues from a centrifuged mixture of protein, fat, other solid materials and aqueous solution of phosphate buffered saline to form an aqueous phase containing the protein. The aqueous phase is then filtered through a filter to separate a clear protein extract from the mixture.
Florida State University | Date: 2015-05-28
A novel Rh(I)-catalyzed approach to synthesizing functionalized (E,Z) dienal compounds has been developed via tandem transformation where a stereoselective hydrogen transfer follows a propargyl Claisen rearrangement. Z-Stereochemistry of the first double bond suggests the involvement of a six-membered cyclic intermediate whereas the E-stereochemistry of the second double bond stems from the subsequent protodemetallation step giving an (E,Z)-dienal. The reaction may be represented by the following sequence.