The First Peoples Hospital of Liangshan Yi Autonomous Prefecture

Liangshan Yi Autonomous Prefecture, China

The First Peoples Hospital of Liangshan Yi Autonomous Prefecture

Liangshan Yi Autonomous Prefecture, China
SEARCH FILTERS
Time filter
Source Type

Yin L.,The First Peoples Hospital of Liangshan Yi Autonomous Prefecture | Wang X.-Y.,The First Peoples Hospital of Liangshan Yi Autonomous Prefecture | Deng J.,The First Peoples Hospital of Liangshan Yi Autonomous Prefecture | Mao S.,The First Peoples Hospital of Liangshan Yi Autonomous Prefecture | And 2 more authors.
Chinese Journal of Interventional Imaging and Therapy | Year: 2014

Objective: To compare the effect of ultrasound-guided interventional treatment in the first-episode and recurrence ovarian endometrioma. Methods: Totally 275 patients of ovarian endometrioma received ultrasound-guided transabdominal or transvaginal injection of ethanol dehydration, among them, there were 122 first-episode patients (first-episode group) and 153 recurrence patients (recurrence group). All the patients were followed-up for 6-12 months after interventional treatment. The recurrence rate of dysmenorrhea and pelvic pain, the cure rate, markedly efficiency rate, the second efficiency rate and inefficiency rate of the two groups were compared. Results: Cysts of the two groups were both completely disappeared instantly after interventional treatment. There were 119 patients (146 cystis, including 60 cystics in first-episode group and 86 cystics in recurrence group) completed the follow-up. At follow-up of 12 months, the recurrence rate of dysmenorrhea and pelvic pain were not statistically difference (both P>0.05) between the two groups. The inefficiency rate of the first-episode group was 13.33% (8/60), which was significantly lower than that of recurrence group (27.91% [24/86], P<0.05). The cure rate, markedly efficiency rate and second efficiency rate was 68.33% (41/60), 5.00% (3/60) and 13.33% (8/60) in first-episode group, and 62.79% (54/86), 2.33% (2/86), and 6.78%(6/86) in recurrence group, with no statistical differences (all P>0.05). Conclusion: Ultrasound-guided interventional treatment of ovarian endometrioma is more effective for the first-episode patients compared with the recurrence patients. Copyright © 2014 by the Press of Chinese Journal of Medical Imaging and Technology.


He G.,Sichuan University | Zou X.,Chongqing Medical University | Chen X.,The First Peoples Hospital Of Liangshan Yi Autonomous Prefecture | Tang R.,Chongqing Medical University | Yan J.,Sichuan University
Genes and Genomics | Year: 2017

The association between five single nucleotide polymorphisms (SNPs) in brain-derived neurotrophic factor (BDNF) gene (rs6265, rs10767664, rs12273539, rs962369 and rs11030101) and allergic inflammatory disease susceptibility has been extensively reported, while the conclusions were inconclusive. The present study was designed to qualitatively and quantitatively evaluate the relationship between the BDNF polymorphisms and allergic disease risks. A comprehensive literature search of the shared public electronic databases was conducted before September 1, 2016. The pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using review manager 5.3. Eleven eligible studies (a total of 5217, 6432, 6432, 6432, 4216 subjects focused on rs6265, rs10767664, rs12273539, rs962369 and rs11030101, respectively) were finally contained. Significant genetic association of rs6265 variant and susceptibility of allergic inflammation was observed under allele contrast, recessive and over-dominant model in the overall analysis. Besides, stratified analysis by ethnicity found that the close relationship between rs6265 polymorphism and increased allergic disease risk of Caucasian was observed under recessive and over-dominant model, as well as under allele contrast, recessive, homozygous and over-dominant model in the Asian. Additionally, subgroup analysis based on the disease types showed the obvious relation of rs6265 and asthma risk in several hereditary model. Moreover, strong association between rs10767664 polymorphism and extraordinary risk of allergic disease was also detected in four genetic models. However, no association was discovered with rs962369, rs12273539 and rs11030101. The present meta-analysis suggested that the SNPs (rs10767664 and rs6265) in the BDNF gene is potentially associated with increased allergic disease susceptibility. © 2017 The Genetics Society of Korea and Springer-Science and Media


He G.,Sichuan University | Zou X.,Chongqing Medical University | Chen X.,The First Peoples Hospital of Liangshan Yi Autonomous Prefecture | Gao T.,Sichuan University | And 3 more authors.
Meta Gene | Year: 2017

Numerous studies have investigated the association between the polymorphisms or haplotypes in interleukin-18 (IL-18) gene promoter and allergic asthma susceptibility, however, the conclusions were controversial. Thus, we performed this comprehensive meta-analysis to evaluate this correlation. Potentially eligible studies were searched in the common electronic database. A total of nine studies for rs1946518, ten studies for rs187238 as well as four studies for haplotypes of the IL-18 promoter were included. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were implemented to assess the strength of the association between polymorphisms or haplotypes and the risk of asthma. Our meta-analysis revealed that a possible association with asthma susceptibility was identified with borderline significance in the overall analysis under dominant genetic model and heterozygous model for IL-18-607 C/A Polymorphism, under the homozygous genetic model for IL-18-137 G/C polymorphism and haplotype of CC in IL-18 gene promoter. Our meta-analysis indicated that genotype AA and CA in rs1946518 may be a protective role in allergic asthma progress, while carriers of genotype GG in rs187238 may be associated with increased allergic asthma risk. Besides, haplotype of CC in the IL-18 gene promoter may be also associated with allergic asthma susceptibility. © 2017


He G.L.,Sichuan University | Chen P.Y.,Zunyi Medical University | Zou X.,Chongqing Medical University | Chen X.,The First Peoples Hospital Of Liangshan Yi Autonomous Prefecture | And 3 more authors.
International Journal of Legal Medicine | Year: 2017

Twenty-three Y-STR loci (DYS576, DYS389I, DYS389 II, DYS448, DYS19, DYS391, DYS481, DYS549, DYS533, DYS438, DYS437, DYS570, DYS635, DYS390, DYS439, DYS392, DYS393, DYS458 DYS456, DYS643, Y-GATA-H4, and DYS385a/b) included in the next-generation PowerPlex® Y23 System were first investigated in 311 unrelated, healthy male individuals from the Yi minority population residing in the Liangshan Yi Autonomous Prefecture, Sichuan, China. A total of 179 alleles and 297 haplotypes were discovered in the Yi group. In total, 285 haplotypes among them were unique, and the remaining 12 haplotypes were observed in two or three individuals. Haplotype discrimination capacity and haplotype diversity were 0.9550 and 0.9989, respectively. Genetic diversity ranged from 0.4550 (DYS437) to 0.9556 (DYS385a/b). Population comparisons between the Yi minority group and 10 Asian meta-populations comprising 58 individual populations were performed. Both multidimensional scaling plots and phylogenetic analyses demonstrated that the genetic structure of the Chinese Yi ethnicity was extremely different compared to Taiwan indigenous inhabitants among 10 Asian meta-populations. Additionally, the genetic structure resemblance of the Yi group was obtained from a geographically close population (Xuanwei Han) or similar language family groups (Thai populations). Besides, our study has demonstrated that the PowerPlex® Y23 System has high polymorphism in a Chinese Yi ethnic population and high discriminatory power for forensic purposes. Population data of the 23 Y-STR obtained from a Yi ethnic population has enriched the Chinese ethnic genetic information. © 2017, Springer-Verlag Berlin Heidelberg.


Fu D.-M.,Southwest University | Fu D.-M.,Chengdu Military Authorities Hospital of PLA | Xiao Q.,Jiulongpo Dental Hospital of Chongqing Bybo Dental Hospital Administrative Ltd Company | Yang Q.-Q.,The First Peoples Hospital Of Suining | And 3 more authors.
Chinese Journal of Tissue Engineering Research | Year: 2016

BACKGROUND: In previous experiments, we have confirmed that platelet rich fibrin has the ability of osteoinduction, and have conducted a preliminary study on its microstructure and biomechanics. However, little is reported on its histology research. OBJECTIVE: To compare the histological changes after implanting platelet-rich fibrin, Bio-Oss and autologous bone and to analyze the pros and cons of platelet-rich fibrin implantation for repair of bone defects. METHODS: As previously reported, animal models of critical bone defects were established respectively on the bilateral femoral condyles of 12 beagle dogs. Then, platelet-rich fibrin, Bio-Oss+collagen membrane (Bio-Oss group) and autologous bone (autologous bone group)+collagen membrane were respectively implanted. At 3, 6, 8 and 12 months, one experimental dog from each group was killed, respectively, and histological observation was performed. Another beagle dog as blank control was enrolled to establish the animal model of critical bone defects, with no implantation. RESULTS AND CONCLUSION: At 3, 6, 8 and 12 months after implantation, there were significant differences in the new bone formation speed and amount between the platelet-rich fibrin group, Bio-Oss group and autologous bone group. These three kinds of bone grafts all had osteoinductive ability to different extents. In the platelet-rich fibrin group, the osteogenic effects were better at 3 and 6 months, and the new bone was similar to natural one; in the autologuos bone group, bone necrosis was noticeable at 3 and 6 months, but the osteogenic effects became better at 8 months, and the new bone was similar to natural one at 12 months; in the Bio-oss group, the osteogenic effects were similar to those in the platelet-rich fibrin group, but the residual of Bio-oss was visible at 12 months; in the blank control group, no bone formed at 3 months, indicating the animal model of critical bone defects was made successfully. In brief, the platelet-rich fibrin has good osteoinductive ability, with shorter time and better quality. © 2016, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.


Wang T.,University of Sichuan | Wang T.,The Authority Hospital of Chengdu Military Region of PLA | Yang Q.-Q.,The First Peoples Hospital Of Suining | Dong L.,The First Peoples Hospital Of Liangshan Yi Autonomous Prefecture | And 4 more authors.
Chinese Journal of Tissue Engineering Research | Year: 2016

BACKGROUND: Insufficient oral soft tissues in the implant zone may have a negative effect on the wound healing and the aesthetic restoration in the late stage. Platelet-rich fibrin can promote the wound healing of soft tissue defects. But there is still a lack of in-depth studies on the promotion of oral soft tissue defects in animal experiments. OBJECTIVE: To compare the repairing effects of platelet-rich fibrin and collagen membrane on soft tissue defects of the hard palate in New Zealand rabbits. METHODS: Fifty-four New Zealand rabbits were randomly divided into three groups (n=14 per group): platelet-rich fibrin group, collagen membrane group and blank control group. A 5 mm-diameter circular full-thickness soft tissue defect was made in the front of the hard palate, 2 mm distant to the rear maxillary incisors and mucosal edge of the bilateral hard palates. Autologous platelet-rich fibrin membrane or collagen membrane were implanted into the defect in the platelet-rich fibrin group and collagen membrane group, respectively. No treatment was given in the blank control group. General observation of the wound and wound healing analysis were performed at days 3, 7, 14, 21, 28, 56 post operation. Hematoxylin-eosin staining, CD31 immunohistochemical staining and Masson staining were used to observe inflammatory reaction, angiogenesis and collagen formation in the surgical site. RESULTS AND CONCLUSION: The wound healing rate was fastest in the platelet-rich fibrin group, and no obvious scar formed. At 3 days post operation, there was no difference in the wound healing rates among the three groups; at 7 days, the wound healing rate in the platelet-rich fibrin group was significantly higher than that in the collagen membrane group and blank control group (P < 0.05). At 3 and 7 days after operation, the inflammatory reaction in the platelet-rich fibrin group was less than that in the collagen membrane and blank control groups (P < 0.05); at 14, 21, 28 and 56 days, there was no significant difference between the three groups. At 7, 14, 21 days after operation, the average absorbance value of CD31 in the platelet-rich fibrin group was significantly higher than that in the collagen membrane and blank control groups (P < 0.05). The average absorbance value of collagen formation in the platelet-rich fibrin group was significantly higher than that in the collagen membrane and blank control groups at 7 days after operation (P < 0.05), significantly higher than that in the blank control group at 14 days (P < 0.05), but lower than that in the collagen membrane and blank control groups at 21, 28 and 56 days after operation (P < 0.05). These findings show that platelet-rich fibrin can reduce inflammatory reactions in the process of wound healing, accelerate the angiogenesis, regulate the metabolism of collagen, reduce the formation of scar and improve the quality of wound healing, thereby promoting the repair of oral soft tissue defects. © 2016, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.


Yang Q.Q.,The First Peoples Hospital Of Suining | Dong L.,The First Peoples Hospital Of Liangshan Yi Autonomous Prefecture | Xiao Q.,Dental Hospital Administrative Ltd Company | Chen H.L.,The Chengdu Military Authorities Hospital of Chinese People | Sun Y.,The Chengdu Military Authorities Hospital of Chinese People
Chinese Journal of Tissue Engineering Research | Year: 2016

BACKGROUND: In clinical, the research on the method and the material of the soft tissue defect of the operation area has been in depth. It will have a positive impact on our exploration and research in this field through the establishment of reliable experimental animal oral soft tissue defect model. OBJECTIVE: To establish a rabbit model of oral soft tissue defects for oral treatment of soft tissue defects in-depth study. METHODS: Eighteen 3-month-old male New Zealand rabbits were enrolled. A tissue ring cutting drill of 5 mm diameter was used to prepare round full-thickness soft tissue defects in the front part of the hard palate and, respectively, from the back of the maxillary incisors, about 2 mm from the hard palate mucosal edge. Morphology and histology were observed at 3, 7, 14, 21, 28 and 56 days after model establishment. RESULTS AND CONCLUSION: (1) Morphological observation: After 3 and 7 days, the wound’s inflammatory reaction was obvious. As the time goes, the inflammatory response subsided, the wound gradually healed. Scar formation was observed at 21, 28 and 56 days after surgery. (2) Histological observation: 3 and 7 days after injury, many inflammatory cells were infiltrating, and tissue necrosis area was larger. At 7 days after surgery, with the extensive formation of connective tissue proliferation and new blood capillaries, the wound gradually shaping completely. (3) Results indicated that a rabbit model of oral soft tissue defects was successfully established, which was in line with the physical laws of wound healing and the characteristics of human oral soft tissue defects healing. © 2017, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.


Xiao Q.,Administrative Ltd Company | Sun Y.,The Chengdu Military Region Authorities Hospital of PLA | Chen H.-L.,The Chengdu Military Region Authorities Hospital of PLA | Zhao F.,The Chengdu Military Region Authorities Hospital of PLA | And 3 more authors.
Chinese Journal of Tissue Engineering Research | Year: 2016

BACKGROUND: At present, many studies have focused on platelet-rich fibrin combined with other bone substitute materials in repair of peri-implant bone defects and sinus lifting, but there is still a lack of research about the platelet-rich fibrin alone in repair of critical-size bone defects. OBJECTIVE: To compare the effect of three kinds of bone substitutes, platelet-rich fibrin, Bio-Oss bone subsitute and autogenous cancellous bone, in repair of bone defects. METHODS: Four areas of cylindrical critical bone defects with a diameter of 6.0 mm and depth of 10.0 mm were prepared in the medial femoral condyle of beagle dogs. Three areas o f bone defects were implanted with autologous platelet-rich fibrin, Bio-Oss bone subsitutes and autologous cancellous bone, respectively. The remaining one area of bone defect was not implanted any substance, as control group. X-ray and Micro-CT detections in bone defect area were conducted after 12 weeksof surgery. RESULTS AND CONCLUSION: (1) X-ray: the density of platelet-rich fibrin group was more higher, but still slightly lower than that of the surrounding normal bone tissue; the density of the Bio-Oss bone substitute group was more lower, but stiil higher than that of the surrounding bone tissues; the density of autologous cancellous bone group was more higher, which was close to that of the surrounding bone tissues; circular low-density images were visible in the control group. (2) Micro-CT: platelet-rich fibrin group was similar with the autogenous cancellous bone group, and their density was slightly lower than that of the surrounding normal bone tissues; the trabecular bone exlibited a clear regular arrangement, and no obvious interface; the Bio-Oss bone substitute group showed a high density image with clear interface; the bone defect area was stiil clearly visible in the control group, with a low-density image. The bone volume fraction and trabecular number in the platelet-rich fibrin and autologous cancelous bone groups were both higher than those in the Bio-Oss bone substitute group (P < 0.05). These results demonstrate that platelet-rich fibrin and autogenous cancellous bone have a similar bone repair effect. © 2016, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.

Loading The First Peoples Hospital of Liangshan Yi Autonomous Prefecture collaborators
Loading The First Peoples Hospital of Liangshan Yi Autonomous Prefecture collaborators