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Shuai W.,First Affiliated Hospital to General Hospital of PLA
Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation | Year: 2011

Clinical experiments are always used to evaluate the safety and validity of medical devices. The experiments have two types of clinical trying and testing. Ethic review must be done by the ethics committee of the medical department with the qualification of clinical research, and the approval must be made before the experiments. In order to ensure the safety and validity of clinical experiments of medical devices in medical institutions, the contents, process and approval criterions of the ethic review were analyzed and discussed.


Du J.,First Affiliated Hospital to General Hospital of PLA | Liu H.,Chongqing Medical University | Liu R.,First Affiliated Hospital to General Hospital of PLA | Yao Y.,First Affiliated Hospital to General Hospital of PLA | And 4 more authors.
Journal of Huazhong University of Science and Technology - Medical Science | Year: 2011

The therapeutic effects of intensive insulin therapy in treatment of traumatic shock combined with multiple organ dysfunction syndrome (MODS) were investigated. A total of 114 patients with traumatic shock combined with MODS were randomly divided into two groups: control group (n=56) treated with conventional therapy, and intensive insulin therapy group (n=58) treated with conventional therapy plus continuous insulin pumping to control the blood glucose level at range of 4.4-6.1 mmol/L. White blood cells (WBC) counts, prothrombin time (PT), serum creatinine (SCr), alanine aminotransferase (ALT), serum albumin and PaO2 were measured before and at the day 1, 3, 5, 7 and 14 after treatment. The incidence of gastrointestinal dysfunction, the incidence of MODS, hospital stay and the mortality were also observed and compared. After intensive insulin therapy, the WBC counts, SCr, ALT and PT were significantly reduced (P<0.05), but the level of serum albumin was significantly increased (P<0.05) at the day 3, 5, 7 and 14. In the meantime, the PaO2 was significantly elevated at the day 3, 5 and 7 (P<0.01) after intensive insulin therapy. The incidence of gastrointestinal dysfunction, the incidence of MODS, the length of hospital stay and the mortality were markedly decreased (P<0.01). The results suggest early treatment with intensive insulin therapy is effective for traumatic shock combined with MODS and can decrease the length of hospital stay and the mortality. © 2011 Huazhong University of Science and Technology and Springer-Verlag Berlin Heidelberg.


Zhang Y.,First Affiliated Hospital to General Hospital of PLA | Zhang H.,First Affiliated Hospital to General Hospital of PLA | Clarke H.D.,Mayo Medical School | Hattrup S.J.,Mayo Medical School
Journal of Arthroplasty | Year: 2012

All charges for patients undergoing unilateral and bilateral hip or knee arthroplasties at 1 hospital in Beijing, China, were identified and assigned to 1 of 11 charge categories: hospital room, nursing, radiology, laboratory, anesthesia, surgery, prosthesis, pharmacy, blood transfusion, materials, and miscellaneous. The prosthesis and pharmacy charges at this institution accounted for approximately 80% of the total charges; compared with published data from institutions in North America and Taiwan, these 2 charges accounted for a greater percentage of total charges. In distinction, labor costs in China accounted for a lower percentage of total charges. Importantly, because the percentage of costs covered by medical insurance was relatively low, a substantial financial burden was imposed on patients that may limit access to joint arthroplasty in China. © 2012 Elsevier Inc.

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