New Ulm, MN, United States
New Ulm, MN, United States

Firmenich SA is a private Swiss company in the perfume and flavor business. It is the largest privately owned company in the field and ranks number two worldwide., Firmenich has created perfumes for over 100 years and produced a number of well-known flavors. Firmenich employs 6,200 people in 64 countries. Major competitors include Givaudan, International Flavors and Fragrances and Symrise. It bought Noville in 2006 and in 2007 acquired Danisco Flavor division. Wikipedia.


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Patent
Firmenich | Date: 2017-05-10

The present invention relates to the field of organic synthesis and more specifically it concerns a process for the preparation of homoallylic alcohol derivatives as defined in formula (I) via a reaction of alkene of formula (II) with an aldehyde.


Patent
Firmenich | Date: 2017-03-22

Provided herein is a method of making a concentrated solution of (S)-1-(3-(((4- amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3- methylbutan-1-one, or a salt or solvate thereof, comprising adding to an aqueous solution: a) a food grade polymer that is soluble in water at or above 0.1% by weight at 20 C to the aqueous solution; b) a sweetener; and c) (S)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5- yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one wherein the concentration of (S)-1- (3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1- yl)-3-methylbutan-1-one, or a salt or solvate thereof, is greater than or equal to 1 ppm, by weight of the total weight of the solution, at 3 C when the pH is less than or equal to 4 or it is greater than or equal to 7 ppm, by weight of the total weight of the solution, at 25 C when the pH is less than or equal to 4. Further provided herein are solutions and beverages prepared by the methods.


Patent
Firmenich | Date: 2015-06-25

The present invention relates to organic-inorganic hybrid core-shell microcapsules encapsulating an active ingredient such as a perfume and having a shell made from the hydrolysis and condensation reaction of particular polyalkoxysilane macro-monomeric compositions.


Patent
Firmenich | Date: 2017-03-15

The present invention relates to a method of producing drimenol and/or drimenol derivatives by contacting at least one polypeptide with farnesyl diphosphate. The method may be performed in vitro or in vivo. The present invention also provides amino acid sequences of polypeptides useful in the method of the invention and nucleic acid encoding the polypeptides of the invention. The method further provides host cells or organisms genetically modified to express the polypeptides of the invention and useful to produce drimenol and /or drimenol derivatives.


Patent
Firmenich and Interquim S.A. | Date: 2017-04-12

A method of enhancing the sweetness of sweetener in a food or beverage product comprising adding Naringenin to the product in an amount of 50 ppm to 200 ppm by weight of the total weight of the product wherein the Naringenin does not block the bitter taste of the product when compared to the beverage without Naringenin. Also provided here is a food or beverage product comprising Naringenin in an amount of from 50 to 200 ppm, by weight, of the total weight of the product, and a sweetener wherein the product is not a product selected from coffee, tea, a cosmetic and a pharmaceutical.


Patent
Firmenich | Date: 2017-03-01

The present invention relates to a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof which is useful as perfuming ingredients.


Patent
Firmenich | Date: 2017-06-07

Provided herein are methods of improving the dissolution rate in water of a compound of Formula (F) in the form of any one of its stereoisomers or a mixture thereof, and wherein n is an integer from 0 to 2; the dotted line represents a carbon-carbon single or double bond; and each of R1 to R4, when taken independently from each other, represents a hydrogen atom or represents a R5 or OR5 group, R5 representing a C1 to C5 alkyl group; and optionally one of the groups R1 to R4 represents -OH; and/or when R1 and R2 are taken together, and/or R3 and R4 are taken together, represent a OCH20 group, provided said groups taken together are adjacent substituents of the phenyl group.


Provided herein is a method of reducing postprandial concentrations of glucose in a subjects blood comprising administering to the subject, prior to or during a meal, an effective amount of a combination of a marine peptide and a fish nucleotide, sufficient to reduce the glucose concentration in the subjects blood. Further provided herein is a method of reducing postprandial concentration of ghrelin in a subjects blood, comprising administering to the subject, prior to or during a meal, an effective amount of a combination of a marine peptide and a fish nucleotide sufficient to increase the blood component wherein the combination is administered to the subject.


Patent
Firmenich | Date: 2017-06-07

Provided herein is a method of flavouring a food comprising grinding a flavour bead onto a food or beverage prior to or contemporaneous with the use of the food or beverage, wherein the particle is in the form of an extruded, glassy bead, comprising a fibrous carrier composition encapsulating a flavour ingredient or composition active ingredient, characterised in that the bead has a cross-section diameter comprised between 3 mm and 15 mm. Further provided here is a flavour mill comprising the bead. The particle or bead comprises an encapsulating carrier composition essentially made of fibrous materials, which are both sugarless and non-cariogenic and an encapsulant, such as a flavour material.


Reversible covalent bond formation under thermodynamic control adds reactivity to self-assembled supramolecular systems, and is therefore an ideal tool to assess complexity of chemical and biological systems. Dynamic combinatorial/covalent chemistry (DCC) has been used to read structural information by selectively assembling receptors with the optimum molecular fit around a given template from a mixture of reversibly reacting building blocks. This technique allows access to efficient sensing devices and the generation of new biomolecules, such as small molecule receptor binders for drug discovery, but also larger biomimetic polymers and macromolecules with particular three-dimensional structural architectures. Adding a kinetic factor to a thermodynamically controlled equilibrium results in dynamic resolution and in self-sorting and self-replicating systems, all of which are of major importance in biological systems. Furthermore, the temporary modification of bioactive compounds by reversible combinatorial/covalent derivatisation allows control of their release and facilitates their transport across amphiphilic self-assembled systems such as artificial membranes or cell walls. The goal of this review is to give a conceptual overview of how the impact of DCC on supramolecular assemblies at different levels can allow us to understand, predict and modulate the complexity of biological systems. © The Royal Society of Chemistry.

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