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May H.-O.,FH Darmstadt | Mausbach P.,Cologne University of Applied Sciences
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics | Year: 2012

The behavior of thermodynamic response functions and the thermodynamic scalar curvature in the supercritical region have been studied for a Lennard-Jones fluid based on a revised modified Benedict-Webb-Rubin equation of state. Response function extrema are sometimes used to estimate the Widom line, which is characterized by the maxima of the correlation lengths. We calculated the Widom line for the Lennard-Jones fluid without using any response function extrema. Since the volume of the correlation length is proportional to the Riemannian thermodynamic scalar curvature, the locus of the Widom line follows the slope of maximum curvature. We show that the slope of the Widom line follows the slope of the isobaric heat capacity maximum only in the close vicinity of the critical point and that, therefore, the use of response function extrema in this context is problematic. Furthermore, we constructed the vapor-liquid coexistence line for the Lennard-Jones fluid using the fact that the correlation length, and therefore the thermodynamic scalar curvature, must be equal in the two coexisting phases. We compared the resulting phase envelope with those from simulation data where multiple histogram reweighting was used and found striking agreement between the two methods. © 2012 American Physical Society.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SEC-2011.3.4-1 | Award Amount: 18.18M | Year: 2012

Significant efforts have been invested to strengthen border ID checks with biometrics Travel Documents embedding electronic chips (ePassport). However, problems appeared regarding fraud in the ePassport issuing process, citizen losing control on their personal data, difficulties in certificates management, and shortcomings in convenience, speed, and efficiency of ID checks, including the access to various remote data bases. FIDELITY is a multi-disciplinary initiative which will analyse shortcomings and vulnerabilities in the whole ePassports life cycle and develop technical solutions and recommendations to overcome them. FIDELITY will demonstrate privacy enhanced solutions to: -Secure issuing processes: authentication of documents, preventing impersonation fraud -Improve ePassport security and usability: authentication processes, ID check speed, accuracy of biometrics, management of certificates, access to remote data bases, convenience of biometric sensors and inspection devices -Better manage lost and stolen passports -Strengthen privacy: privacy-by-design applied to all phases of the ePassport life cycle, systematic anomysation of data and separation of data streams, using novel privacy-enhancing-technologies FIDELITY will strengthen trust and confidence of stakeholders and citizens in ePassports, provide more reliable ID checks, hence hinder criminal movements, and ease implementation of E/E records providing better analysis of migration flows. FIDELITY solutions will be designed for backwards compatibility to be deployed progressively in the existing infrastructure. The FIDELITY consortium is composed of market-leading companies, innovative SME, renowned academia, ethical-sociological-legal experts, and end-users, which will help to define requirements and recommendations and assess results. They will, with the other partners actively promote the project results towards stakeholders and international working groups that elaborate future ePassport standards.

Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: SEC-2013.3.4-2 | Award Amount: 2.26M | Year: 2014

The project ORIGINS aims to study the security of the extended border and more particularily passport breeder document security. The underlying idea of ORIGINS is to improve the security and therefore to restore the confidence in the application process and issuance of e-passports, by filling the gaps in security of breeder documents. Indeed, while some assurance approaches have been implemented in a few countries, they remain insufficient to provide breeder documents in complete security and trustworthiness at a time when this is increasingly necessary. This project will therefore investigate exhaustively the current state of passport breeder documents requirements and issuing practices in Member States/Associated Countries. The identification of common security gaps will lead to the recommendation of possible solutions to overcome the security weaknesses in breeder documents. The project will provide support for issuance bodies and border control communities. It will also promote the standardisation of breeder documents by creating a dedicated working group at a European level. These objectives will be achieved through the establishment of a strong networking environment between key actors in the sector (passport breeder document and e-passport communities, border control community, ministries, industry, SMEs, universities, NGOs, the European Commission, the European Parliament and the Council, ), exchange and dissemination of good practices between relevant communities, the definition and organisation of joint or common initiatives, meetings, conferences, events and with an appropriate management of the action. Broad communication and dissemination actions will be undertaken throughout the project lifecycle. At the same time, it is expected that ORIGINS results will continue to live beyond the end of the project, in particular via think-tank groups built during the project, standardisation groups and the implementation of ORIGINS recommendations.

Wolff K.E.,FH Darmstadt
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2011

Based on Formal Concept Analysis the notion of a Temporal Conceptual Semantic System is introduced as a formal conceptual representation for temporal systems with arbitrary discrete or continuous semantic scales. In this paper, we start with an example of a weather map with a moving high pressure zone to explain the basic notions for Temporal Conceptual Semantic Systems. The central philosophical notion of an object is represented as a formal concept or, more flexible, as a tuple of concepts. Generalizing the idea of a volume of an object in physics we introduce the notion of a trace of an object in some space. This space is described as a continuous or discrete concept lattice. Combining the notion of a trace of an object with the notion of a time granule yields the notion of a state of an object at some time granule. This general notion of a state allows for a clear conceptual understanding of particles, waves and Heisenberg's Uncertainty Relation. Besides these theoretical aspects, Temporal Conceptual Semantic Systems can be used very effectively in practice. That is shown for data of a distillation column using a nested transition diagram. © 2011 Springer-Verlag.

Blendowske R.,FH Darmstadt
Optometry and Vision Science | Year: 2015

Purpose. This article proposes a simple model that describes the quantitative relationship between unaided visual acuity and blur attributed to refractive errors. Methods. The standard model for describing the relationship between visual acuity and blur, as published by Raasch, is used as a starting point to develop a simpler model based on heuristic arguments. The basis of Raasch's data is augmented by published findings in the range of low-level refractive errors. Sphero-cylindrical refractive errors are transformed into a single blur quantity b, also termed dioptric distance, which serves as an input in both models. The possible influence of the cylinder axis and the pupil size is not included. Results. The quite simple model for the unaided minimum angle of resolution, MAR ∝ 1+ b2, nicely matches available data and improves the SE of the regression by a factor of 2 in comparison to Raasch's model. Conclusions. Both models considered in this article describe measurement data equally well. They differ in terms of complexity and functional form. The simple model provides a valid description for low-level refractive errors, where Raasch's model fails. Actual uncertainties in experimental data on unaided visual acuity, especially the frequent lack of information on pupil diameter, prevent meaningful numerical comparison and the refinement of both models. However, theoretical arguments are provided in support of the simple model. Copyright © 2015 American Academy of Optometry.

Braun M.,FH Darmstadt
IEEE Transactions on Information Theory | Year: 2015

We visit generator matrices A0, A1, A2, ⋯ of all k-dimensional subspaces of the n-dimensional vector space over the field with two elements such that two consecutive matrices Ai and Ai+1 differ in exactly one bit. © 2014 IEEE.

Wolff K.E.,FH Darmstadt
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2010

In this paper we introduce the notion of a Temporal Relational Semantic System (TRSS) as a relational extension of a Temporal Conceptual Semantic System (TCSS) as defined by the author in 2007. TCSSs allow to represent states of distributed objects in concept lattices of specified views, the TRSSs enable the user to work in a conceptually simple way with arbitrary relational structures changing temporally. The flexible tools of conceptual scaling can now be applied also to relational structures. That yields for example a clear theoretical notion of the state of a temporal relation at some time granule. The main notions in TRSSs are visualized in some diagrams constructed from an example of a TRSS. © 2010 Springer-Verlag Berlin Heidelberg.

Agency: European Commission | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2014 | Award Amount: 450.00K | Year: 2014

The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to create a holistic informatics platform for rapidly integrating genomic sequences, electronic health records (EHRs) and research repositories to enable personalised medicine strategies for malignant melanoma treatment. The consortium has engaged in a pre-proposal process with active clinical end users who have highlighted the need for more innovative approaches for the treatment of cancer - in particular the treatment of malignant melanoma, including inter alia the ability to rapidly query of geno-phenotype associations in melanoma such as the recently discovered rs2301641 SNP variability with ABCB5 function and CDK4 gene indicators . Hence we aim to develop a scalable HPC framework that allows the semantic interlinking between spatially distributed electronic patients health records, associated genomic sequences and published research, thereby allowing clinicians to make reasoned queries over vast knowledge bases for the diagnosis, treatment and management of malignant melanoma.

The invention relates to novel HDAC inhibitors and a method of making such HDAC inhibitors. The present invention provides novel HDAC inhibitors having a perfluorinated linker between the metal-binding group and the cap group.

The invention is a device for influencing transfer of vibration between two units, one is mounted so that it can vibrate and the other is mounted to be quieted. A parallel circuit is connected indirectly or directly with both units, which comprises at least one elastically deformable element, with an associated first force path and at least one force generator, providing a second force path, oriented parallel to the first force path and associated with a lever, connected indirectly or directly with the one unit, which lever at one end is rotated about a first axis of rotation oriented orthogonally to both force paths.

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