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This study sought to characterize the elderly and their participation in group educational activities, and to verify the sociodemographic and health factors associated with non-participation. It was a cross-sectional survey carried out with 2,142 elderly individuals, using descriptive analysis, Student's t-test and logistical regression (p<0.05). In both groups, the majority of participants were women, 60 - 70 years of age, married with an income of one minimum salary. The elderly participants predominately showed 1-4 years of education, with non-participants 4 - 8. The morbidities most cited by the elderly who participated in educational activities were: hypertension and vision problems. Among non-participants, vision and spinal problems prevailed. In both groups, the greatest percentage was 1 - 3 incapacities. The age range of 80 years and above was associated with a greater chance of non-participation in activities. It is necessary to plan actions that favor participation, thereby contributing to monitor their health conditions. Source

Rocha Rodrigues D.B.,Federal University of Triangulo Mineiro
Clinical & developmental immunology | Year: 2012

Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi. The immune system plays an important role in the reduction of parasite load, but may also contribute to the development of lesions observed during the chronic phase of the disease. We analyzed cytokines produced by inflammatory heart cells in 21 autopsy samples obtained from patients with Chagas' disease divided according to the presence or absence of heart failure (HF). Left ventricular sections were analyzed by immunohistochemistry using antibodies against human IL-4, IFN-γ, TGF-β, TNF-α, and NOS2. In situ mRNA expression was quantified by a Low Density Array. The number of IFN-γ-positive cells was significantly higher than IL-4 positive cells. TNF-α, TGF-β and NOS2 were detected in 65%, 62% and 94% of samples respectively. There was an association between TNF-α-producing cells and the presence of HF. Subjects with HF presented higher levels of STAT4 mRNA, whereas FoxP3 and STAT6 levels were similar in the two groups. A Th1 cytokine pattern predominated in the cardiac inflammatory cell infiltrate of Chagas' disease patients associated with HF. High degree of fibrosis was associated with low NOS2 expression. These results support the idea that Th1 immune responses are involved in heart lesions of Chagas' disease patients. Source

Serqueira E.O.,Federal University of Triangulo Mineiro | Dantas N.O.,Federal University of Uberlandia
Optics Letters | Year: 2014

We report rare evidence of energy transfer from CdSe quantum dots (QDs) to Nd3 ions in a SNAB glass system using absorption electronic transitions of ion as a nonresonant excitation source. However, the luminescence band was observed at 880 nm (4F3?2 ? 4I9?2 transition) under 409 nm excitation only when Nd3 ions were embedded in the SNAB glass system with CdSe QDs. This happened because the Nd3 ions absorbed the photons emitted by CdSe QDs with 409 nm excitation. Band overlap of the QD luminescence band and the ion optical absorption bands caused photon absorption and produced valleys in the QD luminescence spectrum. This overlap contributed to reduction in the lifetime 4F3?2 state. © 2013 Optical Society of America. Source

Caseli L.,Federal University of Sao Paulo | Siqueira J.R.,Federal University of Triangulo Mineiro
Langmuir | Year: 2012

The search for optimized architectures, such as thin films, for the production of biosensors has been challenged in recent decades, and thus, the understanding of molecular interactions that occur at interfaces is essential to improve the construction of nanostructured devices. In this study, we investigated the possibility of using carbon nanotubes in hybrid Langmuir-Blodgett (LB) films of lipids and urease to improve the catalytic performance of the immobilized enzyme. The molecular interactions were first investigated at the air-water interface with the enzyme adsorbed from the aqueous subphase onto Langmuir monolayers of dimyristoylphosphatidic acid (DMPA). The transfer to solid supports as LB films and the subsequent incorporation of carbon nanotubes in the hybrid film permitted us to evaluate how these nanomaterials changed the physical properties of the ultrathin film. Colorimetric measurments indicated that the presence of nanotubes preserved and enhanced the enzyme activity of the film, even after 1 month. These results show that the use of such hybrid films is promising for the development of biosensors with an optimized performance. © 2012 American Chemical Society. Source

We present closed formulas for computing the differential geometry properties of the intersection curve of n-1 implicit hypersurfaces in Rn. These closed formulas include second curvature, third curvature, normal curvature, first geodesic curvature and first geodesic torsion for implicit curves in n-dimensions. © 2012 Elsevier B.V. All rights reserved. Source

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