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Aracaju, Brazil

The Federal University of Sergipe is a Brazilian public institution based in Sergipe, with campi sprawling through the cities of São Cristóvão , Aracaju, Itabaiana, Laranjeiras and Lagarto. Founded in 1967 by the junction of the State's existing colleges, it became its second university and its first, and so far only, public one. As traditionally seen in Brazilian educational system, in which state-banked universities tend to offer better quality of education, it became the State's most reputable and disputed higher education institution, ranking among the country's 40 best universities and Latin America's top 200. Wikipedia.

De Sousa D.P.,Federal University of Sergipe
Molecules | Year: 2011

Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes. © 2011.

AIMS: To evaluate the antinociceptive effects of citronellal (CTL) on formalin-, capsaicin-, and glutamate-induced orofacial nociception in mice and to investigate whether such effects might involve a change in neural excitability. METHODS: Male mice were pretreated with CTL (50, 100, and 200 mg/kg, ip), morphine (5 mg/kg, ip), or vehicle (distilled water plus one drop of Tween 80 0.2%) before formalin (20 microL, 2%), capsaicin (20 microL, 2.5 microg) or glutamate (40 microL, 25 microM) injection into the right vibrissa. Sciatic nerve recordings were made using the single sucrose gap technique in rats. The data obtained were analyzed by ANOVA followed by Dunnett's test for the behavioral analyses and by the Student t test for CAP evaluation. RESULTS: Pretreatment with CTL was effective in reducing nociceptive face-rubbing behavior in both phases of the formalin test, which was also naloxone-sensitive. CTL produced significantly antinociceptive effect at all doses in the capsaicin- and glutamate- tests. Rota-rod testing indicated that such results were unlikely to be provoked by motor abnormality. Recordings using the single sucrose gap technique revealed that CTL (10 mM) could reduce the excitability of the isolated sciatic nerve through a diminution of the compound action potential amplitude by about 42.4% from control recordings. CONCLUSION: These results suggest that CTL might represent an important tool for management and/or treatment of orofacial pain.

Viana A.,Federal University of Sergipe
Computers and Mathematics with Applications | Year: 2015

This paper is devoted to study local existence, uniqueness, and continuous dependence upon the initial data of mild solutions for a diffusive non-autonomous Lotka-Volterra system. Initial data are taken in the Besov space Bp,q,Nσ. © 2015 Elsevier Ltd. All rights reserved.

Lima A.F.,Federal University of Sergipe
Journal of Physics and Chemistry of Solids | Year: 2014

First principles calculations based on density functional theory have been employed to study the electronic, magnetic and optical properties of Co 3O4 in a cubic normal spinel structure. Exchange and correlation effects between electrons were treated by a B3PW91 hybrid functional, which produced better results than others scheme, such as GGA+U or PBE0 hybrid functionals or mBJ semilocal potential. The work focuses on clarifying the nature of the optical absorption bands, which have motivated various theoretical and experimental works in the literature. The calculated optical absorption spectrum was compared with available experimental data. On the basis of this calculated electronic and magnetic structure, the optical absorption peaks (theoretical and experimental) could be satisfactorily explained in terms of d3d charge transfer transitions between both CO2 +→CO2+ and CO3+→CO3+ions. The calculations also predicted that the crystal field splittings at both octahedral and tetrahedral sites in the Co3O4 compound are of the same magnitude. © 2013 Elsevier Ltd. All rights reserved.

Ambrosio R.C.,Federal University of Sergipe | Gewirth A.A.,University of Illinois at Urbana - Champaign
Analytical Chemistry | Year: 2010

Surface-enhanced Raman scattering (SERS) spectra were collected continuously during cyclic voltammetric measurements on silver electrodes in alkaline aqueous solution at room temperature. Three water librational modes as well as the bending mode peak were observed in cathodic potential range. The 2D-COS analysis of spectra collected in LiOH and KOH solutions showed that the librational bands appear prior to the bending band on the cathodic scan, while in CsOH solution the potential dependence of these bands was identical. A comparison of librational band frequencies revealed that the water molecules around Cs+ cations arranged on the electrode surface were poorly hydrogen bonded in contrast to Li+ and K+. The water bending band of spectra collected in LiOH solution was found to be the convolution of two contributions, consistent with a two state model of water arranged on an electrode surface. © 2010 American Chemical Society.

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