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Florianopolis, Brazil

The Federal University of Santa Catarina is a public university in Florianópolis, the capital city of Santa Catarina in southern Brazil. Ranked as the 4th best overall university in Latin America by the Webometrics Ranking of World Universities, it is one of the leading Latin American research universities, being the third largest university in Brazil and the fifth in Latin America, noted for its engineering school, and the only Federal University in the state of Santa Catarina. UFSC is internationally known for the quality of its courses in mechanical engineering, control engineering, sanitary engineering, electrical engineering and dentistry.The organization of its campus is done in the 11 Centers of Education , divided by field of study. Every Center of Education is divided in departments, the largest one being Department of Mechanical Engineering. The oldest is the Center of Juridic science, that is itself the department of Law, which was the first of UFSC's departments to be officially recognized in 1932. Wikipedia.


Torii A.J.,Federal University of Technology of Parana | Lopez R.H.,Federal University of Santa Catarina
Journal of Hydraulic Engineering | Year: 2012

This paper presents the application of the adaptive response surface approach to the reliability analysis of water distribution networks. In this case, the response of the system is approximated by an analytical solution (response surface) and then the reliability problem is solved using first-order reliability methods. This approach is then extended to the analysis of networks that may have to work under several different configurations. This can be a consequence of repairing operations or some other unexpected event, for example. Finally, two numerical examples are presented to discuss the main aspects of the proposed approach. © 2012 American Society of Civil Engineers.


Molkov Y.I.,Drexel University | Zoccal D.B.,University of Sao Paulo | Zoccal D.B.,Federal University of Santa Catarina | Moraes D.J.A.,University of Sao Paulo | And 3 more authors.
Journal of Neurophysiology | Year: 2011

Hypertension elicited by chronic intermittent hypoxia (CIH) is associated with elevated activity of the thoracic sympathetic nerve (tSN) that exhibits an enhanced respiratory modulation reflecting a strengthened interaction between respiratory and sympathetic networks within the brain stem. Expiration is a passive process except for special metabolic conditions such as hypercapnia, when it becomes active through phasic excitation of abdominal motor nerves (AbN) in late expiration. An increase in CO2 evokes late-expiratory (late-E) discharges phase-locked to phrenic bursts with the frequency increasing quantally as hypercapnia increases. In rats exposed to CIH, the late-E discharges synchronized in AbN and tSN emerge in normocapnia. To elucidate the possible neural mechanisms underlying these phenomena, we extended our computational model of the brain stem respiratory network by incorporating a population of presympathetic neurons in the rostral ventrolateral medulla that received inputs from the pons, medullary respiratory compartments, and retrotrapezoid nucleus/parafacial respiratory group (RTN/pFRG). Our simulations proposed that CIH conditioning increases the CO2 sensitivity of RTN/pFRG neurons, causing a reduction in both the CO2 threshold for emerging the late-E activity in AbN and tSN and the hypocapnic threshold for apnea. Using the in situ rat preparation, we have confirmed that CIHconditioned rats under normal conditions exhibit synchronized late-E discharges in AbN and tSN similar to those observed in control rats during hypercapnia. Moreover, the hypocapnic threshold for apnea was significantly lowered in CIH-conditioned rats relative to that in control rats. We conclude that CIH may sensitize central chemoreception and that this significantly contributes to the neural impetus for generation of sympathetic activity and hypertension. © 2011 the American Physiological Society.


Prim S.R.,Santa Catarina State University | Folgueras M.V.,Santa Catarina State University | de Lima M.A.,Santa Catarina State University | Hotza D.,Federal University of Santa Catarina
Journal of Hazardous Materials | Year: 2011

Pigments that meet environmental and technology requirements are the focus of the research in the ceramic sector. This study focuses on the synthesis of ceramic pigment by encapsulation of hematite in crystalline and amorphous silica matrix. Iron oxide from a metal sheet rolling process was used as chromophore. A different content of hematite and silica was homogenized by conventional and high energy milling. The powders obtained after calcinations between 1050 and 1200°C for 2. h were characterized by X-ray diffraction and SEM analysis. The pigments were applied to ceramic enamel and porcelain body. The effect of pigment was measured by comparing L*. a*. b* values of the heated samples. Results showed that the color developed is influenced by variables such as oxide content employed, conditions of milling and processing temperature. The results showed that the use of pigment developed does not interfere in microstructural characteristics of pigmented material. The best hue was obtained from samples with 15. wt% of chromophore, heated at 1200°C in amorphous silica matrix. © 2011 Elsevier B.V.


Celeste R.K.,Federal University of Rio Grande do Sul | Bastos J.L.,Federal University of Santa Catarina
Revista de Saude Publica | Year: 2014

To estimate the mid-point of an open-ended income category and to assess the impact of two equivalence scales on income-health associations. Data were obtained from the 2010 Brazilian Oral Health Survey (Pesquisa Nacional de Saúde Bucal-SBBrasil 2010). Income was converted from categorical to two continuous variables (per capita and equivalized) for each mid-point. The median mid-point was R$ 14,523.50 and the mean, R$ 24,507.10. When per capita income was applied, 53% of the population were below the poverty line, compared with 15% with equivalized income. The magnitude of income-health associations was similar for continuous income, but categorized equivalized income tended to decrease the strength of association.


This article discusses training and continuing medical education for indigenous health workers and health professionals in indigenous health under the guidelines of the Brazilian National Healthcare Policy for Indigenous Peoples, which is currently behind schedule and incomplete as part of the official government agenda. Based on inter-sector proposals for health training by the Ministries of Health and Education, the article highlights the case of indigenous healthcare, emphasizing that government initiatives in this area still need to incorporate the concept of continuing education, a powerful tool for fostering intercultural dialogue and orienting health practices.


Tavares R.S.,Federal University of Para | da Silva D.M.,Federal University of Santa Catarina
Revista gaúcha de enfermagem / EENFUFRGS | Year: 2013

This study aimed to know the types of support offered by the network of social support and implications on hypertensive life. Qualitative study whose methodology was based on Grounded Theory. 35 people were interviewed between October 2008 and August 2010, 22 hypertensive compulsorily enrolled in HIPERDIA at a Health Unit in Belém / PA, 5 family members, 5 health professionals and 3 representatives of community institutions, referenced by hypertensive patients, as members of the network support Data were subjected to coding procedures: analysis, comparison and categorization. The category "Identifying the types of social support offered to people in their living with hypertension" was the Intervening Condition of the Theory The types of emotional informational and instrumental support originated mainly from family relationships and may mean alternative treatments,featuring a care focused on people with hypertension and their network of relationships which requires attention from healthcare professionals, including nurses.


Costa L.C.,Federal University of Santa Catarina
Revista brasileira de epidemiologia = Brazilian journal of epidemiology | Year: 2010

This study aimed to estimate the prevalence of dissatisfaction with body image and associated socio-economic, behavioral and dietary factors in female university students from a public university in Florianopolis, SC. Body image was assessed by the Body Shape Questionnaire (BSQ-34) in a sample of 220 students. Nutritional status was investigated by body mass index (BMI), waist circumference (WC), and body fat percentage (%BF). Socio-economic characteristics (age, monthly household income, and parental schooling) as well as energy intake and going on restrictive diets were also investigated. Factors associated with dissatisfaction with body image were analyzed by multivariate Poisson regression analysis. The prevalence of dissatisfaction with body image was 47.3% (95% CI 40.7; 53.9). Nutritional status by BMI and going on a diet to lose weight were the variables associated with body dissatisfaction. Results showed a high prevalence of indicators of rejection of their physical fitness among university students, which signals toward the need for nutritional education actions at universities in order to clarify and prevent abnormal eating attitudes among students.


Amestoy S.C.,Federal University of Santa Catarina
Revista brasileira de enfermagem | Year: 2010

Qualitative study, descriptive and exploratory which aimed to ascertain the role of an institution of higher education and hospital training and continuing education of nurse-leaders. Was developed during the months of February and March 2008, with the participation of eleven nurses from a large hospital in the southern region of Rio Grande do Sul. For data collection was carried out semi-structured interviews and focus groups. Using the Content Analysis for the treatment of data, two categories emerged: the role of higher education institution in the training of nurses, leaders and role of the hospital in continuing education of nurses-leaders. There is the existence of gaps related to the teaching of leadership and development of competence in the hospital context.


The purpose of this descriptive, retrospective, documental study is to describe the use of peripherally inserted central catheters (PICC) in a neonatal and pediatric intensive care unit regarding their insertion, maintenance, and removal. This study also characterized the population which received the catheter through descriptive and statistical analysis of 176 instruments filled out by nurses, in a two year period. The population attended consisted of 125 patients, mainly premature (43.2%) and male (60%). The basilic and cephalic (43.2%) veins were primarily used for the insertion of a 1.9Fr (85.8%) catheter. The success rate was 98.9% in the punctures, but anticipated removal occurred due to obstruction (25%), infiltration (18%), suspected contamination (16.6%), traction (13.9%), rupture (11.2%), accidental removal (8.3%), phlebitis (4.2%), cyanosis (1.4%), and migration (1.4%), with an average period of permanence of 14.5 days. In order to maintain the catheter professional education and preparation are required to qualify care.


Vettore M.V.,University of Sheffield | de Amorim Marques R.A.,Area Tecnica de Saude Bucal | Peres M.A.,University of Adelaide | Peres M.A.,Federal University of Santa Catarina
Revista de Saude Publica | Year: 2014

OBJECTIVE: To estimate the prevalence and geographical distribution of periodontal disease in the Brazilian adult population and its associations with contextual and individual social inequalities. METHODS: Data from adults aged 35 to 44 who participated in the 2010 Brazilian Brazilian Oral Health Survey (SBBrasil 2010) (n = 9,564) were used. The Community Periodontal Index (CPI) and clinical attachment loss (CAL) were used to defi ne "moderate to severe" periodontal disease (CPI > 2 and CAL > 0) and "severe" periodontal disease (CPI > 2 and CAL > 1). Contextual social inequalities assessed were Human Development Index and income inequalitiy (Gini Index). Other contextual variables were integration of oral health teams in the Family Health Programme and the percentage of adult smokers. Multilevel logistic regression models for participants with complete data (n = 4,594) were used to estimate odds ratios (OR) and 95% confi dence intervals (95%CI) between social inequalities and periodontal disease. RESULTS: The prevalence of "moderate to severe" and "severe" periodontal disease in Brazilian adults was 15.3% and 5.8%, respectively, with considerable variation across municipalities. Of the contextual variables, income inequality was independently associated with "severe" periodontal disease (OR = 3.0, 95%CI 1.5;5.9). Lower oral health teams coverage was associated with both defi nitions of periodontal disease whereas the percentage of smokers remained associated with "moderate to severe" periodontal disease. Older adults, brown skin color, males and those with lower family income and less schooling were more likely to both periodontal conditions. CONCLUSIONS: In Brazil, the prevalence of periodontal disease varied across the municipalities and according to defi nition of periodontal disease. Income inequality played a signifi cant role in the occurrence of "severe" periodontal disease. Individual characteristics of social position were associated with both forms of periodontal disease.


Ghisi E.,Federal University of Santa Catarina
Water Resources Management | Year: 2010

Rainwater harvesting has been studied in different countries as a way of easing water availability problems and reducing potable water demand in buildings. The most important factor relating to the efficiency of a rainwater system is the correct sizing of the rainwater tank. Therefore, the objective of this article is to assess the influence of rainfall, roof area, number of residents, potable water demand and rainwater demand on rainwater tank sizing. The analysis was performed by using computer simulation and by considering daily rainfall data for three cities located in the state of São Paulo, Brazil. The roof areas considered were 50, 100, 200 and 400 m2; the potable water demands were 50, 100, 150, 200, 250 and 300 l per capita per day; the rainwater demands were taken as a percentage of the potable water demand, i.e., 10% to 100% at increments of 10%; and the number of residents was two and four. Results indicated a wide variation of rainwater tank sizes for each city and also for each parameter. The main conclusion that can be made from the study is that rainwater tank sizing for houses must be performed for each specific situation, i. e., considering local rainfall, roof area, potable water demand, rainwater demand and number of residents. Therefore, sizing rainwater tanks according to local tradition is not recommended as it may incur low efficiency. © Springer Science+Business Media B.V. 2009.


Paduani C.,Federal University of Santa Catarina | Jena P.,Virginia Commonwealth University
Chemical Physics Letters | Year: 2013

First-principles calculations based on the density functional theory (DFT) are performed to study the structure, stability and electron affinity of sodium and magnesium borohydrides. With successive attachments of BH4 complexes to the metal atom a superhalogen behavior is identified for the Na(BH4)2 and Mg(BH4)3 clusters, whose electron affinities reach 5.07 eV and 5.13 eV, respectively. As Mg(BH 4)3 cluster is used as a building block to decorate the Mg atom the electron affinity is pushed up to a higher level (6.18 eV) which classifies the Mg[Mg(BH4)3]3 moiety as a hyperhalogen. © 2012 Elsevier B.V. All rights reserved.


Mafra Jr. L.L.,Federal University of Parana | Tavares C.P.S.,Federal University of Parana | Schramm M.A.,Federal University of Santa Catarina
Journal of Applied Phycology | Year: 2014

In southern Brazil, mixotrophic dinoflagellates belonging to the Dinophysis acuminata complex have recently been involved in diarrheic shellfish poisoning episodes through the production of lipophilic toxins such as okadaic acid (OA) and dinophysistoxin-1 (DTX-1). The present investigation used a combination of laboratory cultures and field surveys at three large estuarine systems in that region to examine toxin retention in Dinophysis spp. cells under optimum or growth-limiting conditions. This study represents the first successful culture of a Dinophysis isolate from the Atlantic South America region. Starved D. acuminata complex cells reached 5.6-fold higher cellular OA quotas (up to 18 pg cell-1) than Mesodinium rubrum-fed cultures 20 days after inoculation in the laboratory. Moreover, in field samples, light-limited cells at the bottom of a stratified water column were less abundant, yet 6.6- to 11-fold more toxic (up to 26.4 pg OA and 1.7 pg DTX-1 cell-1) than those located at the illuminated surface. This phenomenon of toxin retention by slow-dividing cells may partially explain the enormous variation in cell toxin quota found within Dinophysis spp. populations from a single location, and it may have serious implications for cell count-based monitoring program in bivalve aquaculture areas. In fact, only low to moderate OA levels were detected in the digestive glands of oysters Crassostrea spp. (up to 17.8 ng g-1) and the guts and livers of filter-feeding fish (44.7 ng g-1) during the present study, despite the relatively high Dinophysis cell densities (up to 19,500 cells L-1) found in the field. © 2013 Springer Science+Business Media Dordrecht.


de Freitas Lins Neto E.M.,Federal Rural University of Pernambuco | Peroni N.,Federal University of Santa Catarina | de Albuquerque U.P.,Federal Rural University of Pernambuco
Economic Botany | Year: 2010

Traditional Knowledge and Management of Umbu (Spondias tuberosa, Anacardiaceae): An Endemic Species from the Semi-Arid Region of Northeastern Brazil. Spondias tuberosa, or umbu, is an arboreal species that is important both as an alternative economic and subsistence resource for rural communities in the semi-arid, northeastern regions of Brazil. The aim of this work was to study the knowledge, uses, local gathering practices, and management systems of S. tuberosa that are part of the traditions of the communities in this region. An ethnobotanical survey was conducted in two stages in a rural community in the state of Pernambuco. In the first stage, all of the dwellings were visited and both the men and the women who were responsible for their house were interviewed. In the second stage, people who were identified as having a direct relationship with the resource were questioned more thoroughly about the species. Knowledge of S. tuberosa is equally distributed in the community; there are no significant differences in knowledge between men and women, or across age groups. The food category is the most important for both human and animal nourishment. The main forms of local management are tolerance and gathering of fruit. Fruit gathering is directly affected by, in order of importance, taste (sweet-sour), size, and quantity of fruit pulp. The usefulness of S. tuberosa contributes considerably to the tolerance of this species in both managed areas and as part of the native vegetation. © 2010 The New York Botanical Garden.


Kupek E.,Federal University of Santa Catarina
Revista da Sociedade Brasileira de Medicina Tropical | Year: 2014

Previous studies have shown high residual risk of transfusing a blood donation contaminated by human immunodefi ciency virus (HIV) or hepatitis C virus (HCV) in Brazil and motivated the development of a Brazilian platform for simultaneous detection of both viruses by nucleic acid amplifi cation test (NAT) denominated HIV/HCV Bio-Manguinhos/ Fundação Oswaldo Cruz (FIOCRUZ). The objective of this study was to verify seroprevalence, incidence and residual risk for both viruses before and after the implementation of NAT. Methods: Over 700,000 blood samples from all blood banks in the southern Brazilian State of Santa Catarina were analyzed during the period between January 2007 and July 2013. Results: Compared with the period preceding the NAT screening, HIV prevalence increased from 1.38 to 1.58 per 1,000 donors, HIV incidence rate increased from 1.22 to 1.35 per 1,000 donor-years, and HIV residual risk dropped almost 2.5 times during the NAT period. For HCV, seroprevalence increased from 1.22 to 1.35 per 1,000 donors, incidence dropped from 0.12 to 0.06 per 1,000 donor-years, and residual risk decreased more than 3 times after the NAT implementation. Conclusions: NAT reduced the duration of the immunologic window for HIV and HCV, thus corresponding to approximately 2.5- and 3-fold respective residual risk reductions. © 2014 Sociedade Brasileira de Medicina Tropical. All rights reserved.


Zwald M.L.,Washington University in St. Louis | Hipp J.A.,Washington University in St. Louis | Corseuil M.W.,Federal University of Santa Catarina | Dodson E.A.,Washington University in St. Louis
Preventing Chronic Disease | Year: 2014

Introduction: Attributes of the built environment can influence active transportation, including use of public transportation. However, the relationship between perceptions of the built environment and use of public transportation deserves further attention. The objectives of this study were 1) to assess the relationship between personal characteristics and public transportation use with meeting national recommendations for moderate physical activity through walking for transportation and 2) to examine associations between personal and perceived environmental factors and frequency of public transportation use. Methods: In 2012, we administered a mail-based survey to 772 adults in St Louis, Missouri, to assess perceptions of the built environment, physical activity, and transportation behaviors. The abbreviated International Physical Activity Questionnaire was used to assess walking for transportation and use of public transportation. The Neighborhood Environment Walkability Scale was used to examine perceptions of the built environment. Associations were assessed by using multinomial logistic regression. Results: People who used public transportation at least once in the previous week were more likely to meet moderate physical activity recommendations by walking for transportation. Age and employment were significantly associated with public transportation use. Perceptions of high traffic speed and high crime were negatively associated with public transportation use. Conclusion: Our results were consistent with previous research suggesting that public transportation use is related to walking for transportation. More importantly, our study suggests that perceptions of traffic speed and crime are related to frequency of public transportation use. Future interventions to encourage public transportation use should consider policy and planning decisions that reduce traffic speed and improve safety.


Bershad N.J.,1621 Santiago Drive | Bermudez J.C.M.,Federal University of Santa Catarina
Digital Signal Processing: A Review Journal | Year: 2011

Normalized forms of adaptive algorithms are usually sought in order to obtain convergence properties independent of the input signal power. Such is the case of the well-known Normalized LMS (NLMS) algorithm. The Least-Mean Fourth (LMF) adaptive algorithm has been shown to outperform LMS in different situations. However, the LMF stability is dependent on both the signal power and on the adaptive weights initialization. This paper studies the behavior of two normalized forms of the LMF algorithm for Gaussian inputs. Contrary to what could be expected, the mean-square stability of both normalized algorithms is shown to be dependent upon the input signal power. Thus, the usefulness of the NLMF algorithm is open to question. © 2011 Elsevier Inc. All rights reserved.


Sanmartin F.A.,Andres Bello University | Laurindo J.B.,Federal University of Santa Catarina | Segura L.A.,Andres Bello University
Drying Technology | Year: 2011

This work presents results of Monte Carlo simulations of isothermal drying of a nonhygroscopic porous media initially saturated with a sugar solution. The porous media is represented by a two-dimensional network of cubic pores connected by throats with a given radius distribution. The considered network had just one open side (the three other sides were sealed) from which water evaporation occurred. Water evaporation, hydraulic flow, and diffusivity of sucrose in water are considered in the physical model. It was considered that drying occurred under isothermal conditions (low drying rates) and that the capillary forces surpass the viscous forces, as in invasion percolation. It was also considered that water evaporation inside the network of pores and throats causes solution concentration, which remains at the corners, allowing hydraulic connection throughout the whole network. At each simulation step, a single meniscus moves through a particular pore segment with the higher displacing force. As drying progresses, air replaces the solution. Determination of the mechanism prevailing at any given drying stage requires calculation of evaporation. In other words, each step of the simulation involves finding the solution to three systems of equations: the vapor pressure field in the vapor phase, the pressure field in the liquid phase, and the solutes' concentration in the liquid phase. Herein, we report results of drying curves calculated as a function of the sucrose and water saturation and of the distribution of liquid, sucrose, and vapor as drying advances. The results presented in this work showed that network models are a powerful tool for investigating the influence of the main mechanisms controlling drying at its different stages; that is, from liquid saturation condition to very low saturation (end of drying). Despite the applied simplifications, the model can capture the main aspects of drying of liquids and solutions present in porous media. © 2011 Taylor & Francis Group, LLC.


Leite da Silva A.M.,Federal University of Itajuba | Rezende L.S.,Federal University of Itajuba | Honorio L.M.,Federal University of Juiz de fora | Manso L.A.F.,Federal University of Santa Catarina
IET Generation, Transmission and Distribution | Year: 2011

This study presents a performance comparison of metaheuristics to solve transmission expansion planning (TEP) problems in power systems. The proposed methodology includes the search for the least cost solution, bearing in mind investments and operational costs related to ohmic transmission losses. The multi-stage nature of the TEP is also taken into consideration. Case studies on a small system and on a real sub-transmission network are presented and discussed. © 2011 © The Institution of Engineering and Technology.


Oliveira S.V.G.,Regional University of Blumenau | Barbi I.,Federal University of Santa Catarina
IEEE Transactions on Industrial Electronics | Year: 2011

This paper presents a new three-phase step-up dc-dc converter with a three-phase high-frequency (HF) isolation transformer in an average current-mode controlled closed loop. This converter was developed for industrial applications where the dc input voltage is lower than the output voltage, for instance, in installations fed by battery units, photovoltaic arrays, or fuel cell systems. The converter's main characteristics are reduced input ripple current, step-up voltage, HF transformer, reduced output-voltage ripple due to three-pulse output current, and the presence of only three active switches connected to the same reference, this being a main advantage of this converter. By means of a specific switch modulation, the converter allows two operational regions, each one depending upon the number of switches in overlapping conditions-if there are two switches, it is called R2 region, and if there are three switches, it is called R3 region. An average current-mode control strategy is applied to input-current and output-voltage regulation. Theoretical expressions and experimental results are presented for a 6.8-kW prototype, operating in the R2 region, and for a 3.4-kW prototype, operating in the R3 region, both in continuous conduction mode. © 2009 IEEE.


Boissier O.,Ecole Nationale Superieure des Mines de Saint - Etienne CMP | Bordini R.H.,Federal University of Rio Grande do Sul | Hubner J.F.,Federal University of Santa Catarina | Ricci A.,University of Bologna | Santi A.,University of Bologna
Science of Computer Programming | Year: 2013

This paper brings together agent oriented programming, organisation oriented programming and environment oriented programming, all of which are programming paradigms that emerged out of research in the area of multi-agent systems. In putting together a programming model and concrete platform called JaCaMo which integrates important results and technologies in all those research directions, we show in this paper, with the combined paradigm, that we prefer to call "multi-agent oriented programming", the full potential of multi-agent systems as a programming paradigm. JaCaMo builds upon three existing platforms: Jason for programming autonomous agents, Moise for programming agent organisations, and CArtAgO for programming shared environments. This paper also includes a simple example that illustrates the approach and discusses some real-world applications that have been or are being developed with JaCaMo. © 2012 Elsevier B.V. All rights reserved.


Stadnik M.J.,Federal University of Santa Catarina
Phytoparasitica | Year: 2014

Ulvan is an algal polysaccharide known for its ability to induce resistance to plant diseases such as the Glomerella leaf spot of apple caused by Colletotrichum gloeosporiodes. This study was aimed at investigating microscopically, in tests in vitro and in vivo, whether ulvan interferes in the development of pre-infective structures of C. gloeosporioides. Conidial germination and appressoria formation were monitored hourly on agar and cellophane, and at 48 h on water- and ulvan-treated susceptible as well as resistant apple leaves. Amendment of agar with ulvan (10 mg ml−1) enhanced the germination and resulted in longer germ tubes at 7 h of incubation. On cellophane it significantly delayed appressoria formation up to 8 h, but later after 14 h increased the number of appressoria per conidium. Spraying of susceptible leaves with ulvan 6 days before inoculation decreased disease severity by 50%. This was associated with inhibition of appressoria formation and stimulus in growth of germ tubes, without interfering with conidial germination, when compared with both water-treated control and resistant plants. Appressorium formation occurred preferentially on anticlinal walls of epidermal cells and its location was not influenced by host resistance or by ulvan treatment. This study suggests a new mode of action for ulvan interfering with appressorium formation that could protect apple plants against C. gloeosporioides infection. © 2014, Springer Science+Business Media Dordrecht.


De Franca J.A.,State University Londrina | Stemmer M.R.,Federal University of Santa Catarina | Franca M.B.D.M.,State University Londrina | Piai J.C.,State University Londrina
Pattern Recognition | Year: 2012

In computer vision, camera calibration is a necessary process when the retrieval of information such as angles and distances is required. This paper addresses the multi-camera calibration problem with a single dimension calibration pattern under general motions. Currently, the known algorithms for solving this problem are based on the estimation of vanishing points. However, this estimate is very susceptible to noise, making the methods unsuitable for practical applications. Instead, this paper presents a new calibration algorithm, where the cameras are divided into binocular sets. The fundamental matrix of each binocular set is then estimated, allowing to perform a projective calibration of each camera. Then, the calibration is updated for the Euclidean space, ending the process. The calibration is possible without imposing any restrictions on the movement of the pattern and without any prior information about the cameras or motion. Experiments on synthetic and real images validate the new method and show that its accuracy makes it suitable also for practical applications. © 2012 Elsevier Ltd.


Information is essential for nursing care because nurses in subsidizing clinical decision making for the resolution and reduction of health problems. This review integrative study identified publications in national and international journals the major data standards, terminologies and classification systems used in health care and nursing. The research was conducted on MEDLINE, CINAHL and SCIELO using the keywords: Information Systems, Nursing Informatics, Medical Informatics, Computerized Medical Records Systems, Terminology and Nomenclature of Medicine Systematized. It was selected 91 articles which were analyzed in two empirical categories: "data standards for health care and nursing" and "terminologies and classification systems in nursing" From the various data standards, terminologies and classification systems, it is important that nursing take ownership of them aiming to improve and renew the quality of care.


Schmoeller R.,Federal University of Santa Catarina
Revista gaúcha de enfermagem / EENFUFRGS | Year: 2011

This study reviews theoretical production concerning workloads and working conditions for nurses. For that, an integrative review was carried out using scientific articles, theses and dissertations indexed in two Brazilian databases, Virtual Health Care Library (Biblioteca Virtual de Saúde) and Digital Database of Dissertations (Banco Digital de Teses), over the last ten years. From 132 identified studies, 27 were selected. Results indicate workloads as responsible for professional weariness, affecting the occurrence of work accidents and health problems. In order to adequate workloads studies indicate some strategies, such as having an adequate numbers of employees, continuing education, and better working conditions. The challenge is to continue research that reveal more precisely the relationships between workloads, working conditions, and health of the nursing team.


Boing A.F.,Federal University of Santa Catarina | Antunes J.L.F.,University of Sao Paulo
Ciencia e Saude Coletiva | Year: 2011

This study sought to describe the main characteristics of epidemiological studies that investigated the association between socioeconomic conditions and head and neck cancer. Research was carried out on the Medline (International Science Literature), Lilacs (Latin American and Caribbean Health Sciences Literature) and Scielo (Scientific Electronic Library Online) databases, as well as the references cited in the articles obtained through the primary search of the aforementioned databases. The publication period considered included 38 years (1970-2007) and the analysis was restricted to articles in Spanish, English or Portuguese. Twenty-five studies were selected, 15 that outlined case-control, four ecological and six that combined information from official databases, such as censuses and cancer or death records. Most cases reported an association between lower socioeconomic conditions and head and neck cancer. The most used indexes were occupation and education. Few studies investigated medication, aiming to point out which proximal factors operate in the investigated association. Additional studies, with uniform criteria to effect the adjustments in the regression models and sufficient samples, are required to inquire this dimension.


Acevedo N.C.,Iowa State University | Block J.M.,Federal University of Santa Catarina | Marangoni A.G.,University of Guelph
Langmuir | Year: 2012

The effects of processing using a scraped surface heat exchanger (SSHE) before and after adding unsaturated monoglyceride (UM) on blends of fully hydrogenated soybean oil (FHSO) and soybean oil (SO) were studied. Mixtures of 40:60 and 45:55 FHSO:SO were melted at 80 °C for 30 min and crystallized statically or in the SSHE (shear rate of 25 s-1) at a cooling rate of 9 °C/min. Upon shearing and UM addition, polymorphic transformations toward more (β) or less (β') stable forms were governed by the combination between system concentration, composition, and crystallization conditions, as determined by differential scanning calorimetry and powder X-ray diffraction. Nuclear magnetic resonance was used to measure the solid fat content (SFC) development which showed to increase with processing conditions due to the high nucleation rate induced. Processing conditions greatly affected the nano- and microcrystalline structures which were characterized by polarized light microscopy (PLM), cryogenic transmission electron microscopy (Cryo- TEM), and Scherrer analysis of the powder X-ray diffraction data. Crystallization under shear promoted the longitudinal growth of the nanoplatelets; nevertheless, meso structural elements showed a decrease in their dimensions under the same crystallization conditions. The relative oil loss determined gravimetrically was inversely related to the elastic modulus and yield stress of the sheared fat blends, and values were closer to the desirable usability ranges for bakery applications. Our results suggest that fully hydrogenated fats can be functionalized by crystallization in a SSHE and/or by judicious addition of an unsaturated emulsifier. © 2012 American Chemical Society.


Altimari P.,University of Rome La Sapienza | Mancusi E.,University of Sannio | Mancusi E.,Federal University of Santa Catarina
Chemical Engineering and Processing: Process Intensification | Year: 2013

We study the stabilisation of travelling temperature wave trains in periodically forced networks of catalytic reactors where methanol synthesis takes place. Temperature wave train solutions reproduce the inter-stage cooling effect of multistage fixed bed reactors and are therefore particularly attractive in terms of methanol conversion. However, these solutions are generally stable within narrow operating windows and always coexist with solutions characterised by lower methanol conversion. We implement a feedback control strategy with the switching time as a manipulated variable to ensure the stability of temperature wave trains. The reaction front velocity is estimated during each cycle based on temperature measurements. This allows the switching time to be computed so that the reaction front does not cross a prescribed set-point position. Indications on how to place temperature sensors and to select the set-point and controller parameters are provided. Numerical simulations demonstrating the ability of the implemented control law to prevent the transition to undesired solutions in the presence of disturbances both in the operating regime and during start-up are reported. © 2012 Elsevier B.V.


Pawlowski A.,University of Almeria | Guzman J.L.,University of Almeria | Normey-Rico J.E.,Federal University of Santa Catarina | Berenguel M.,University of Almeria
Journal of Process Control | Year: 2012

This paper deals with the measurable disturbance rejection problem in Generalized Predictive Control (GPC). First, it is analyzed how the unconstrained GPC algorithm with implicit disturbance compensation can be interpreted as a typical feedback plus feedforward control scheme, where the main feature is that the feedforward action includes future estimations of the measurable disturbances. Then, it is shown that classical GPC cannot always eliminate the effect of measurable disturbances even using perfect disturbance models and having exact disturbance estimations along the prediction horizon. To overcome this problem a particular GPC tuning condition is proposed, which allows the improved GPC controller to eliminate the disturbance effect even in those cases where causality and instability problems can appear in the relation between the dynamics of the load disturbance and the process output with the dynamics of the control signal and the process output. Since the new tuning condition for disturbance compensation in GPC leads to a high bandwidth in the feedback loop, a two degrees of freedom control scheme within the Filtered Smith Predictor (FSP)-based GPC framework has been implemented to improve the robustness capabilities of the control law. Simulation examples are presented to show the main advantages of the proposed control scheme, including a realistic simulation based on a greenhouse climate control problem where estimators for the main process disturbances are also designed. © 2012 Elsevier Ltd. All rights reserved.


Alves M.M.,Federal University of Santa Catarina | Svaiter B.F.,IMPA
Mathematical Programming | Year: 2016

In a recent Math. Program. paper, Eckstein and Silva proposed a new error criterion for the approximate solutions of augmented Lagrangian subproblems. Based on a saddle-point formulation of the primal and dual problems, they proved that dual sequences generated by augmented Lagrangians under this error criterion are bounded and that their limit points are dual solutions. In this note, we prove a new result about the convergence of Fejér-monotone sequences in product spaces (which seems to be interesting by itself) and, as a consequence, we obtain the full convergence of the dual sequence generated by augmented Lagrangians under Eckstein and Silva’s criterion. © 2014, Springer-Verlag Berlin Heidelberg and Mathematical Optimization Society.


Ramos C.F.,State University of Rio de Janeiro | Zamoner A.,Federal University of Santa Catarina
Frontiers in Endocrinology | Year: 2014

Leptin is primarily expressed in white adipose tissue; however, it is expressed in the hypothalamus and reproductive tissues as well. Leptin acts by activating the leptin receptors (Ob-Rs). Additionally, the regulation of several neuroendocrine and reproductive functions, including the inhibition of glucocorticoids and enhancement of thyroxine and sex hormone concentrations in human beings and mice are leptin functions. It has been suggested that thyroid hormones (TH) could directly regulate leptin expression. Additionally, hypothyroidism compromises the intracellular integration of leptin signaling specifically in the arcuate nucleus. Two TH receptor isoforms are expressed in the testis, TRa and TRb, with TRa being the predominant one that is present in all stages of development. The effects of TH involve the proliferation and differentiation of Sertoli and Leydig cells during development, spermatogenesis, and steroidogenesis. In this context, TH disorders are associated with sexual dysfunction. An endocrine and/or direct paracrine effect of leptin on the gonads inhibits testosterone production in Leydig cells. Further studies are necessary to clarify the effects of both hormones in the testis during hypothyroidism. The goal of this review is to highlight the current knowledge regarding leptin and TH in the testis. © 2014 Ramos and Zamoner.


Study of the prevalence of smoking among school children, using secondary data from the Survey School "Doing Research - Monitoring of Smoking in School", conducted by the Centre for Oncologic Research of Santa Catarina. Included variables such as age, the starting in smoking, level of knowledge about the subject, among others. It was found that 41.6% of students smoked sometime in life, no statistical difference between the sexes. Among those who have tried, 38.3% did so between 7 and 11 years. The analysis provided a characterization of the prevalence of risk factors, subsidizing a more effective prevention of nursing and its integration in schools.


Zoccal D.B.,Federal University of Santa Catarina | Machado B.H.,University of Sao Paulo
Respiratory Physiology and Neurobiology | Year: 2010

It is well known that the respiration modulates sympathetic outflow in basal conditions. Recordings of sympathetic nerve activity demonstrated that central respiratory activity produces rhythmical oscillations in sympathetic discharge that appear mainly during inspiratory phase. This led us to hypothesize that changes in the mechanisms regulating the central entrainment between respiratory and sympathetic activities may contribute to sympathetic overactivity and hypertension. This issue was addressed using rats submitted to chronic intermittent hypoxia (CIH), in which we evaluated whether or not the sympathetic overactivity and hypertension observed in these animals were linked to changes in respiratory pattern. We verified that under baseline conditions, CIH rats exhibited a reduction in post-inspiratory activity of vagus nerve and an enhanced late-expiratory activity in abdominal motor nerve. As a consequence of this altered expiratory pattern, we observed that CIH rats showed an additional burst in sympathetic activity phase-locked with the enhanced late-E expiratory activity. These findings pointed out that the entrainment between pontine-medullary expiratory and sympathetic neurons of CIH rats is strengthened, indicating for the first time in this experimental model that changes in the coupling of respiratory and sympathetic activities may contribute to hypertension. Subsequent studies performed in other models of hypertension also demonstrated similar changes, supporting the concept that alterations in central mechanisms of respiratory-sympathetic coupling is a novel and important mechanism to be considered in the pathogenesis of hypertension. © 2010 Elsevier B.V.


Catapan R.C.,University of Lisbon | Oliveira A.A.M.,Federal University of Santa Catarina | Costa M.,University of Lisbon
Experimental Thermal and Fluid Science | Year: 2011

Industrial processes where the heating of large surfaces is required lead to the possibility of using large surface porous radiant burners. This causes additional temperature uniformity problems, since it is increasingly difficult to evenly distribute the reactant mixture over a large burner surface while retaining its stability and keeping low pollutant emissions. In order to allow for larger surface area burners, a non-uniform velocity profile mechanism for flame stabilization in a porous radiant burner using a single large injection hole is proposed and analyzed for a double-layered burner operating in open and closed hot (laboratory-scale furnace, with temperature-controlled, isothermal walls) environments. In both environments, local mean temperatures within the porous medium have been measured. For lower reactant flow rate and ambient temperature the flame shape is conical and anchored at the rim of the injection hole. As the volumetric flow rate or furnace temperature is raised, the flame undergoes a transition to a plane flame stabilized near the external burner surface. However, the stability range envelope remains the same in both regimes. © 2010 Elsevier Inc.


Loch-Neckel G.,Federal University of Santa Catarina | Koepp J.,Instituto Heliopolis Of Tecnologia Y Gestion Of La Innovacion
Revista de Neurologia | Year: 2010

Aim. To provide an updated view of the difficulties due to barriers and strategies used to allow the release of drugs in the central nervous system. Introduction. The difficulty for the treatment of many diseases of the central nervous system, through the use of intravenous drugs, is due to the presence of barriers that prevent the release of the same: the blood-brain barrier, bloodcerebro spinal fluid barrier and the blood-arachnoid barrier. Development. The blood-brain barrier is the main barrier for the transport of drugs in the brain that also acts as a immunologic and metabolic barrier. The endothelial cells of the blood-brain barrier are connected to a junction complex through the interaction of transmembrane proteins that protrude from de inside to the outside, forming a connection between the endothelial cells. The transport of substances to the brain depends on the mechanisms of transport present in the barrier and the diffusion of these compounds also depends on the physicochemical characteristics of the molecule. Some diseases alter the permeability of the blood-brain barrier and thus the passage of drugs. Strategies such as the use of methods for drug delivery in the brain have been investigated. Conclusions. Further details regarding the mechanisms of transport across the blood-brain barrier and the changes in neuropathology would provide important information about the etiology of diseases and lead to better therapeutic strategies. © 2010 Revista de Neurología.


Ruviaro M.,WEG Equipamentos Eletricos S.A. | Runcos F.,WEG Equipamentos Eletricos S.A. | Sadowski N.,Federal University of Santa Catarina | Borges I.M.,WEG Equipamentos Eletricos S.A.
IEEE Transactions on Industrial Electronics | Year: 2012

This paper analyzes a 90-kW brushless doubly fed three-phase induction machine in which a wound rotor circuit is connected to a rotary transformer. It presents the advantages of substituting brushes and slip rings by a rotary transformer. In addition, it shows the rotary transformer design and presents the doubly fed induction machine operation. The steady-state model considers electrical circuit techniques to provide information about current, power factor, and efficiency on load. Equivalent circuit parameters are obtained through laboratory tests under a prototype. Comparisons between simulation and measurement results attest the good performance of the adopted model. © 2011 IEEE.


Hanazaki N.,Federal University of Santa Catarina
Scientometrics | Year: 2015

Ethnobiology is a clearly interdisciplinary field, with several connections to other research approaches, such as studies examining traditional ecological knowledge (TEK). The central question investigated is if Brazilian studies are disproportionately attached to the prefix “ethno” when compared to the profiles of other countries with high contributions to these scientific fields. I used a bibliometric review to investigate this question and discussed several outcomes of the resulting patterns. I retrieved 8470 articles, 6117 using keywords associated with TEK and 2954 using keywords associated with ethnobiology and related subfields. A unique scenario emerges only for Brazil, where there is a stronger attachment to the ethno prefix than the rest of the world, which reflects the history of these scientific approaches and the context of scientific production. © 2015, Akadémiai Kiadó, Budapest, Hungary.


Objective To determine the association between low levels of physical activity and consumption of fruits and vegetables among adolescents. Methods This cross-sectional study included 2,057 adolescents aged 13 to 18 years from the city of Aracaju, Northeastern Brazil. We analyzed the level of physical activity, consumption of fruits and vegetables by standardized and validated questionnaires. The control variables were sex, age, socioeconomic status, maternal education, alcohol consumption and smoking. For data analysis, univariate and multivariate logistic regression were used, with a significance level of 5%. Results The prevalence of low levels of physical activity was 81.9%; the inadequate consumption of fruits ocurred in 79.1% and the inadequate consumption of vegetables in 90.6%. Adolescents who consumed few fruits daily had an increase in 40% of chance of being insufficiently active and, for those who consumed few vegetable,s the likelihood of being insufficiently active was 50% higher, compared to those who had adequate intake of these foods. Conclusions Low levels of physical activity were associated with inadequate fruit and vegetable intake among adolescents in a city in northeastern Brazil. These findings suggest that insufficiently active adolescents have other unhealthy behaviors that may increase the risk of chronic diseases in adulthood. © 2015 Associação de Pediatria de São Paulo. Published by Elsevier Editora Ltda. All rights reserved.


Maiello A.,SantAnna School of Advanced Studies | Viegas C.V.,Federal University of Santa Catarina | Frey M.,SantAnna School of Advanced Studies | D. Ribeiro J.L.,Federal University of Rio Grande do Sul
Environmental Science and Policy | Year: 2013

Scholars agree that governance of the public environment entails cooperation between science, policy and society. This requires the active role of public managers as catalysts of knowledge co-production, addressing participatory arenas in relation to knowledge integration and social learning. This paper deals with the question of whether public managers acknowledge and take on this task. A survey accessing Directors of Environmental Offices (EOs) of 64 municipalities was carried out in parallel for two regions - Tuscany (Italy) and Porto Alegre Metropolitan Region (Brazil). The survey data were analysed using the multiple correspondence method. Results showed that, regarding policy practices, EOs do not play the role of knowledge co-production catalysts, since when making environmental decisions they only use technical knowledge. We conclude that there is a gap between theory and practice, and identify some factors that may hinder local environmental managers in acting as catalyst of knowledge co-production, raising a further question for future research. © 2012 Elsevier Ltd.


Wysin G.M.,Kansas State University | Figueiredo W.,Federal University of Santa Catarina
Physical Review B - Condensed Matter and Materials Physics | Year: 2012

The dynamics of gyrotropic vortex motion in a thin circular nanodisk of soft ferromagnetic material is considered. The demagnetization field is calculated using two-dimensional Green's functions for the thin-film problem and fast Fourier transforms. At zero temperature, the dynamics of the Landau-Lifshitz-Gilbert equation is simulated using fourth-order Runge-Kutta integration. Pure vortex initial conditions at a desired position are obtained with a Lagrange multipliers constraint. These methods give accurate estimates of the vortex restoring force constant k F and gyrotropic frequency, showing that the vortex core motion is described by the Thiele equation to very high precision. At finite temperature, the second-order Heun algorithm is applied to the Langevin dynamical equation with thermal noise and damping. A spontaneous gyrotropic motion takes place without the application of an external magnetic field, driven only by thermal fluctuations. The statistics of the vortex radial position and rotational velocity are described with Boltzmann distributions determined by k F and by a vortex gyrotropic mass m G=G2/k F, respectively, where G is the vortex gyrovector. © 2012 American Physical Society.


Studies have been carried out to identify the best anthropometric predictor of chronic diseases in different populations. To verify the relation between anthropometric measures and risk factors (lipid profile and blood pressure) for cardiovascular diseases. Transversal study carried out with 180 males and 120 females, with mean age 39.6+/-10.6 years old. Body mass index (BMI), waist circumference (WC), body fat percentage (%BF), waist-to-hip ratio (WHR), lipid profile, glycemia and blood pressure were the variables assessed. BMI, WC and WHR were higher among males, and %BF were higher among females (p<0.001). The proportion of altered cases of WHR and %BF in relation to LDL-cholesterol and total cholesterol (TC) was higher among males. The individuals considered normal for WC presented alteration in the values of LDL-c, TC and HDL-cholesterol. There was a correlation between BMI and WC (males: r=0.97 and females: r=0.95; p<0.001). Among males, the best correlation (p<0.001) was presented between WC and WHR (r=0.82) and among females, %BF and WC (r=0.80). Triglycerides (TG) presented correlation to WHR (males: r=0.992; females r=0.95; p<0.001), and to WC (males: r=0.82; females r=0.79; p<0.001). In the multiple analysis (Prevalence ratio - PR, Confidence interval - CI), the BMI were associated with total cholesterol (PR=1.9; 95%CI 1.01-3.69; p=0.051) among males and slightly associated with TG/HDL-cholesterol (PR= 1.8; IC95% 1.01-3.45; p=0.062) among females. BMI and WHR were the anthropometric indicators with strongest relation to lipid profile in both sex groups. This data support the hypothesis that BMI and WHR may be considered as risk factors for cardiovascular disease.


Coutinho D.,Federal University of Santa Catarina | Wouwer A.V.,University of Mons
IET Control Theory and Applications | Year: 2013

This study proposes a multiple-input/multiple-output robust approach to the control of bioprocesses based on a cascaded-loop strategy. The internal loop is a classical input-to-output feedback linearising controller which is obtained from the nominal dynamics of the bioprocess. Then, the outer loop is designed based on the internal model principle to obtain zero steady-state tracking error (and disturbance rejection) for constant signals while ensuring the robust stability of the overall closed-loop system. In addition, a robust Luenberger-like observer is proposed to estimate unmeasured state variables for the feedback linearising control law. The approach is applied to the simultaneous control of biomass and substrate concentrations in a perfusion/chemostat bioreactor, where the simulation results demonstrate the effectiveness of the proposed control strategy. © 2013 The Institution of Engineering and Technology.


Veleirinho B.,University of Aveiro | Ribeiro-Do-Valle R.M.,Federal University of Santa Catarina | Lopes-Da-Silva J.A.,University of Aveiro
Materials Letters | Year: 2011

Novel hybrid fibrous membranes with potential application on the biomedical field were successfully developed via electrospinning of blend solutions of two biocompatible and biodegradable polymers, poly (3-hydroxybutyrate-co- hydroxyvalerate) [PHBV] and chitosan. The effect of solvent, using different proportions of trifluoracetic acid (TFA) and 1,1,1,3,3,3-hexafluoro-2- isopropanol (HFIP), PHBV/chitosan ratio, and chitosan molecular weight on solution spinnability, fiber morphology and size, and in vitro degradation were investigated. Continuous nanofiber structures were obtained from pristine PHBV to a PHBV/chitosan ratio of 2:3 (w/w), at 10% (w/v) total polymer concentration. In general, main fiber average diameters increased as chitosan content and molecular weight increased and decreased with the decrease of HFIP content in the solvent. In vitro dissolution tests revealed that the hybrid fibers show much higher degradation rates than the neat PHBV. © 2011 Elsevier B.V. All rights reserved.


Barneche D.R.,Macquarie University | Kulbicki M.,CIRAD - Agricultural Research for Development | Floeter S.R.,Federal University of Santa Catarina | Friedlander A.M.,University of Hawaii at Manoa | And 2 more authors.
Ecology Letters | Year: 2014

Fishes contribute substantially to energy and nutrient fluxes in reef ecosystems, but quantifying these roles is challenging. Here, we do so by synthesising a large compilation of fish metabolic-rate data with a comprehensive database on reef-fish community abundance and biomass. Individual-level analyses support predictions of Metabolic Theory after accounting for significant family-level variation, and indicate that some tropical reef fishes may already be experiencing thermal regimes at or near their temperature optima. Community-level analyses indicate that total estimated respiratory fluxes of reef-fish communities increase on average ~2-fold from 22 to 28 °C. Comparisons of estimated fluxes among trophic groups highlight striking differences in resource use by communities in different regions, perhaps partly reflecting distinct evolutionary histories, and support the hypothesis that piscivores receive substantial energy subsidies from outside reefs. Our study demonstrates one approach to synthesising individual- and community-level data to establish broad-scale trends in contributions of biota to ecosystem dynamics. © 2014 John Wiley & Sons Ltd/CNRS.


Paduani C.,Federal University of Santa Catarina
Molecular Physics | Year: 2014

In this work, first-principles calculations using the density functional theory are performed to study the structure, stability and electronic properties of lithium borohydrides (boranes) and lithium aluminohydrides (alanates). With the attachment of BH4 and AlH4 complexes to the Li atom, the electron affinity increases to 5.22 eV and 4.34 eV, in the clusters Li(BH4)2 and Li(AlH4)2, respectively, which indicate superhalogen behaviour. For the alanates, by decorating the Li atom with the superhalogen moiety, the electron affinity increases to 4.64 eV, in the large-sized cluster Li[Li(AlH4) 2]2. The substitution of Al for B leads to larger NBO charges on the H atoms, as a result of the electron- donating character of the Al atom. The results show that, besides larger gravimetrical storage capacities, the boranes also have higher electron affinities than the alanates in the large-sized clusters. The significant HOMO-LUMO differences indicate that the new moieties, which are highly reactive, are chemically very stable species. © 2013 Taylor & Francis.


de Mello A.L.F.,Federal University of Santa Catarina
Clinical Interventions in Aging | Year: 2015

Data on the oral health of the elderly depict a worrying situation, with an elevated prevalence of caries and moderate periodontal disease, frequent edentulism, and numerous cases of dry mouth and oral cancer. There is wide evidence that periodontitis is a risk factor for certain systemic diseases, and impaired oral health has been associated with mastication and nutritional problems, especially among the elderly, with highly negative effects on their quality of life. In this nonsystematic review, the authors discuss the importance of evaluating the oral health of the geriatric population in a comprehensive manner, beyond simple clinical assessments. © 2015 Gil-Montoya et al.


Grillo E.,Federal University of Santa Catarina
Epilepsy and Behavior | Year: 2015

Objective: This was a bibliographic search to address the quality of evidence in clinical reports supporting the assertion that brain MRI signal abnormalities are a direct consequence of seizures. Methods: The search on PubMed was performed by applying the following inclusion criteria: a) original case reports, b) in humans, c) as single case reports or series of patients, d) of visually detected acute MRI signal abnormalities, e) attributable directly to seizures, and f) published in English. Bibliographic references of initially selected publications were reviewed for additional articles. Full texts of selected publications were read for information regarding clinical, EEG, and MRI features. Moreover, claimed evidence supporting seizure-induced excitotoxicity was assessed. Results: The search resulted in 91 publications corresponding to 413 cases. There was a wide range of clinical features and EEG and MRI abnormalities. Premorbid or comorbid conditions were present in many cases, and some of them are potential causes of MRI changes. Claimed evidence for MRI signal abnormalities as a direct consequence of ictal activity was mostly based on the similarity with previous reports, animal models, reversibility, congruent EEG, MRI changes not respecting vascular territories, and ruling out other etiologies. Conclusions: Evidence supporting the notion of seizure-induced excitotoxicity is questionable in the studied reports of postictal MRI abnormalities. © 2015 Elsevier Inc.


Shoemaker C.A.,U.S. Department of Agriculture | Martins M.L.,Federal University of Santa Catarina | Xu D.-H.,U.S. Department of Agriculture | Klesius P.H.,U.S. Department of Agriculture
Parasitology Research | Year: 2012

The effect of Ichthyophthirius multifiliis (Ich) parasitism on survival, hematology and bacterial load in channel catfish, Ictalurus punctatus, previously exposed to Edwardsiella ictaluri was studied. Fish were exposed to E. ictaluri 1 day prior to Ich in the following treatments: (1) infected by E. ictaluri and Ich at 2,500 theronts/fish; (2) infected by E. ictaluri only; (3) infected by Ich at 2,500 theronts/fish only; and (4) non infected control. Mortality was significantly higher in fish previously exposed to E. ictaluri and then infected by Ich (71.1 %). Mortalities were 26.7 %, 28.9 % and 0 % for fish infected by E. ictaluri only, by Ich only and non-infected control, respectively. Quantitative polymerase chain reaction demonstrated the presence of E. ictaluri in the brain, gill, kidney and liver of fish infected with E. ictaluri regardless of Ich parasitism. At day 8, E. ictaluri parasitized fish had significantly more bacteria present in the brain, gill and liver, with no bacteria detected in these organs in the E. ictaluri-only treatment, suggesting that the bacteria persisted longer in parasitized fish. Decreased red blood cells count and hematocrit in fish at days 8 and 19 after co-infection suggests chronic anemia. Lymphocyte numbers significantly decreased in all infected treatments versus the non-infected controls at days 2, 8 and 19. Lymphopenia suggests that lymphocytes were actively involved in the immune response. Bacterial clearance was probably influenced by the stress of parasitism and/or the mucosal response induced by ectoparasitic Ich that resulted in the higher mortality seen in the co-infected treatment. © 2012 Springer-Verlag (outside the USA).


Dall'Agnol D.,Federal University of Santa Catarina
Journal of Medical Ethics | Year: 2016

This paper advances a new moral epistemology and explores some of its normative and practical, especially bioethical, implications. In the first part, it shows that there is moral knowledge and that it is best understood in terms of knowing-how. Thus, moral knowledge cannot be analysed purely in the traditional terms of knowing-that. The fundamental idea is that one knowshow to act morally only if she is capable of following the right normative standards. In the second part, the paper discusses ways of integrating two expressions of moral knowing-how, namely caring and respecting into a coherent normative theory. It builds up the concept of respectful care as the central ingredient of such a normative theory. Finally, it illustrates how respectful care may transform some of our current clinical bioethical practices.


Paduani C.,Federal University of Santa Catarina
Journal of Magnetism and Magnetic Materials | Year: 2011

Results of first-principles calculations of the electronic structure for the ordered compounds Ni3Pd and Pd3Ni at the equilibrium volume with L12 structure reveal that the Ni atoms carry an enhanced moment and that an induced moment is found on the Pd atoms. The Ni moment is higher in Pd3Ni, whereas the Pd moment differs only slightly for these compounds. Large bulk moduli are found (341.34 GPa for Ni3Pd and 314.35 GPa for Pd3Ni), and an abrupt collapse of the magnetic moment is observed in Pd3Ni under lattice compression. The results indicate good conductivity for these compounds as well as half-metallicity for Ni3Pd. © 2011 Elsevier B.V. All rights reserved.


Chen J.,University of Technology of Troyes | Richard C.,University of Nice Sophia Antipolis | Bermudez J.C.M.,Federal University of Santa Catarina | Honeine P.,University of Technology of Troyes
IEEE Transactions on Signal Processing | Year: 2011

Dynamic system modeling plays a crucial role in the development of techniques for stationary and nonstationary signal processing. Due to the inherent physical characteristics of systems under investigation, nonnegativity is a desired constraint that can usually be imposed on the parameters to estimate. In this paper, we propose a general method for system identification under nonnegativity constraints. We derive the so-called nonnegative least-mean-square algorithm (NNLMS) based on stochastic gradient descent, and we analyze its convergence. Experiments are conducted to illustrate the performance of this approach and consistency with the analysis. © 2011 IEEE.


Ruther R.,Federal University of Santa Catarina | Zilles R.,University of Sao Paulo
Energy Policy | Year: 2011

In the developed world, grid-connected photovoltaics (PVs) are the fastest-growing segment of the energy market. From 1999 to 2009, this industry had a 42% compound annual growth-rate. From 2009 to 2013, it is expected to grow to 45%, and in 2013 the achievement of grid parity - when the cost of solar electricity becomes competitive with conventional retail (including taxes and charges) grid-supplied electricity - is expected in many places worldwide. Grid-connected PV is usually perceived as an energy technology for developed countries, whereas isolated, stand-alone PV is considered as more suited for applications in developing nations, where so many individuals still lack access to electricity. This rationale is based on the still high costs of PV when compared with conventional electricity. We make the case for grid-connected PV generation in Brazil, showing that with the declining costs of PV and the rising prices of conventional electricity, urban populations in Brazil will also enjoy grid parity in the present decade. We argue that governments in developing nations should act promptly and establish the mandates and necessary conditions for their energy industry to accumulate experience in grid-connected PV, and make the most of this benign technology in the near future. © 2010 Elsevier Ltd.


Farina M.,Federal University of Santa Catarina | Rocha J.B.T.,Federal University of Santa Maria | Aschner M.,Vanderbilt University
Life Sciences | Year: 2011

Neurological disorders are common, costly, and can cause enduring disability. Although mostly unknown, a few environmental toxicants are recognized causes of neurological disorders and subclinical brain dysfunction. One of the best known neurotoxins is methylmercury (MeHg), a ubiquitous environmental toxicant that leads to long-lasting neurological and developmental deficits in animals and humans. In the aquatic environment, MeHg is accumulated in fish, which represent a major source of human exposure. Although several episodes of MeHg poisoning have contributed to the understanding of the clinical symptoms and histological changes elicited by this neurotoxicant in humans, experimental studies have been pivotal in elucidating the molecular mechanisms that mediate MeHg-induced neurotoxicity. The objective of this mini-review is to summarize data from experimental studies on molecular mechanisms of MeHg-induced neurotoxicity. While the full picture has yet to be unmasked, in vitro approaches based on cultured cells, isolated mitochondria and tissue slices, as well as in vivo studies based mainly on the use of rodents, point to impairment in intracellular calcium homeostasis, alteration of glutamate homeostasis and oxidative stress as important events in MeHg-induced neurotoxicity. The potential relationship among these events is discussed, with particular emphasis on the neurotoxic cycle triggered by MeHg-induced excitotoxicity and oxidative stress. The particular sensitivity of the developing brain to MeHg toxicity, the critical role of selenoproteins and the potential protective role of selenocompounds are also discussed. These concepts provide the biochemical bases to the understanding of MeHg neurotoxicity, contributing to the discovery of endogenous and exogenous molecules that counteract such toxicity and provide efficacious means for ablating this vicious cycle. © 2011 Elsevier Inc.


Lopez R.H.,Federal University of Santa Catarina | Beck A.T.,University of Sao Paulo
Journal of the Brazilian Society of Mechanical Sciences and Engineering | Year: 2012

In deterministic optimization, the uncertainties of the structural system (i.e. dimension, model, material, loads, etc) are not explicitly taken into account. Hence, resulting optimal solutions may lead to reduced reliability levels. The objective of reliability based design optimization (RBDO) is to optimize structures guaranteeing that a minimum level of reliability, chosen a priori by the designer, is maintained. Since reliability analysis using the First Order Reliability Method (FORM) is an optimization procedure itself, RBDO (in its classical version) is a double-loop strategy: the reliability analysis (inner loop) and the structural optimization (outer loop). The coupling of these two loops leads to very high computational costs. To reduce the computational burden of RBDO based on FORM, several authors propose decoupling the structural optimization and the reliability analysis. These procedures may be divided in two groups: (i) serial single loop methods and (ii) unilevel methods. The basic idea of serial single loop methods is to decouple the two loops and solve them sequentially, until some convergence criterion is achieved. On the other hand, uni-level methods employ different strategies to obtain a single loop of optimization to solve the RBDO problem. This paper presents a review of such RBDO strategies. A comparison of the performance (computational cost) of the main strategies is presented for several variants of two benchmark problems from the literature and for a structure modeled using the finite element method. Copyright © 2012 by ABCM.


Paduani C.,Federal University of Santa Catarina | Jena P.,Virginia Commonwealth University
International Journal of Hydrogen Energy | Year: 2013

The role of Ti and Ti-based catalysts such as TiCl3 and TiF 3 in the dehydrogenation of Mg(BH4)2 has been studied using a cluster approach and density functional theory. The optimized geometry of Mg(BH4)2 clusters mimics the structure it has in the crystalline form, but undergoes significant geometric distortion as well as changes in the natural bond orbital (NBO) charge after the addition of the catalysts. While all the catalysts lower the hydrogen desorption energy, elemental Ti appears to be the best catalyst followed by TiCl3 and TiF3. The lowering of the hydrogen desorption is shown to be due to the weakening of the BH bond which is caused by the interaction of Ti with H and Mg. Copyright © 2012, Hydrogen Energy Publications, LLC.


Blends of citric acid-modified thermoplastic starch (TPS) and low density polyethylene (LDPE) were prepared by reactive extrusion (REX) and characterized by scanning electron microscopy (SEM) of the fragile fracture surfaces, Fourier-transform infrared spectroscopy (FTIR), water absorption in 53% relative humidity environment and by X-ray diffraction. The modified TPS was prepared by the reactive extrusion of a mixture of corn starch, citric acid and glycerol (30%). TPS-LDPE blends were then prepared by the processing of TPS and PEBD both in pellets in a single screw extruder. It was observed an important compatibilization effect, attributed to the reduction of TPS melt viscosity and consequently the reduction of the interfacial tension between TPS and PEBD phases. The FTIR spectra showed shifting of starch bands confirming the compatibilization effect of citric acid. Important change on blend morphology as function of the TPS modification were observed, in particular for the blends prepared with the addition of 1,0 - 1,5% AC which showed a more homogeneous and finer dispersed phase.


Cardemil J.M.,Diego Portales University | Da Silva A.K.,Federal University of Santa Catarina
Applied Thermal Engineering | Year: 2016

This thermodynamically based study focuses on the thermal performance of power cycles using CO2 as the working fluid. The work considers numerous aspects that can influence the cycle's performance, such as the type of cycle (i.e., Rankine or Brayton), its configuration (i.e., with and without a recuperator), and different operational conditions (i.e., heat source temperature and the upper and lower operating pressures of the CO2). To account for all possible scenarios, a thermodynamic routine was especially implemented and linked to a library that contained all the thermodynamics properties of CO2. The results are mostly presented in terms of the absolute and relative 1st and 2nd Law efficiencies of CO2 as well as the cycle's scale, here represented by the global conductance (UA) of the heat exchangers used within the cycle. For the relative performance assessment, four other working fluids, commonly used in energy conversion cycles, were considered (i.e., ethane, toluene, D4 siloxane and water). As expected, the absolute performance results indicate a strong dependence of the cycle's efficiencies on the operational conditions. As for the relative performance, the results suggest that while the CO2's 1st Law efficiency might be lower than other fluids, its exergetic efficiency can be significantly higher. Furthermore, the calculations also indicate that the CO2's needed global conductance is potentially lower than competing fluids (e.g., toluene) for certain operational conditions, which suggests that CO2-based power plants can be more compact, since they might require smaller heat exchangers to produce a reference power output of 1 kW. © 2015 Elsevier Ltd. All rights reserved.


De Lima K.F.,Pontifical Catholic University of Parana | Lenzi A.,Federal University of Santa Catarina | Barbieri R.,Pontifical Catholic University of Parana | Barbieri R.,Santa Catarina State University
Applied Acoustics | Year: 2011

The aim of this work is to show the application of shape and parametric optimization techniques in the study of reactive silencers with extended inlet and outlet ducts. Parametric optimization is employed to evaluate the appropriate size of the inlet and outlet ducts. Shape optimization is employed to establish the proper profile of these ducts in order to improve the acoustic features of these mufflers in a specific frequency range. The objective function used in the optimization processes is defined through the average transmission loss (TL) for the desired frequency range. This type of objective function is strongly non-linear and the genetic algorithm, GA, was chosen as a mathematical method for determining the maximum of this function. The Finite Element Method with an axisymmetric formulation along with the modified four-parameter method are used to calculate the TL(ω). The Hermite polynomials were used in the shape optimization in order to obtain local boundary approximations with C 1 continuity. The results showed the optimization efficiency of the inlet ducts profile for acting in specific frequency ranges with gains up to 20 dB with respect to silencers without shape optimization. The numerical analyses agree well with experimental results. © 2010 Elsevier Ltd. All rights reserved.


MacHado M.V.T.,Federal University of Rio Grande do Sul | Da Silva M.L.L.,Federal University of Santa Catarina
Physical Review C - Nuclear Physics | Year: 2011

The cross sections for the glueball candidates in quasireal photon-photon collisions and on central diffraction processes (i.e., double Pomeron exchange) in heavy-ion interactions at the Relativistic Heavy-Ion Collider (RHIC) and the Large Hadron Collider (LHC) are computed. The rates for these distinct production channels are compared, and they may be a fruitful approach to the investigation of glueballs. © 2011 The American Physical Society.


Pelinson A.M.,Federal University of Santa Catarina | Shapiro I.L.,Federal University of Juiz de fora
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2011

The anomaly-induced effective action is a useful tool for deriving the contributions coming from quantum effects of massless conformal fields. It is well known that such corrections in the higher derivative vacuum sector of the gravitational action provide the same exponential inflation (Starobinsky model) as the cosmological constant term. At the same time, the presence of a classical electromagnetic field breaks down the exponential solution. In this Letter we explore the role of the anomaly-induced term in the radiation sector and, furthermore, derive the "equation of state" and the scaling laws for all terms in the Einstein equations. As one could expect, the scaling law for the vacuum anomaly-induced effective action is the same as for the cosmological constant. © 2010 Elsevier B.V.


Cruz M.P.,Federal Rural University of Pernambuco | Peroni N.,Federal University of Santa Catarina | Albuquerque U.P.,Federal Rural University of Pernambuco
Journal of Ethnobiology and Ethnomedicine | Year: 2013

Background: Despite being an ancient practice that satisfies basic human needs, the use of wild edible plants tends to be forgotten along with associated knowledge in rural communities. The objective of this work is to analyze existing relationships between knowledge, use, and management of native wild edible plants and socioeconomic factors such as age, gender, family income, individual income, past occupation and current occupation. Methods: The field work took place between 2009 and 2010 in the community of Carão, Altinho municipality, in the state of Pernambuco in northeastern Brazil. We conducted semi-structured interviews with 39 members of the community regarding knowledge, use and management of 14 native wild edible plants from the Caatinga region, corresponding to 12 vegetable species. In parallel, we documented the socioeconomic aspects of the interviewed population (age, gender, family income, individual income, past occupation and current occupation). Results: Knowledge about edible plants was related to age but not to current occupation or use. Current use was not associated with age, gender or occupation. The association between age and past use may indicate abandonment of these resources.Conclusion: Because conservation of the species is not endangered by their use but by deforestation of the ecosystems in which these plants grow, we suggest that the promotion and consumption of the plants by community members is convenient and thereby stimulates the appropriation and consequent protection of the ecosystem. To promote consumption of these plants, it is important to begin by teaching people about plant species that can be used for their alimentation, disproving existing myths about plant use, and encouraging diversification of use by motivating the invention of new preparation methods. An example of how this can be achieved is through events like the " Preserves Festival". © 2013 Cruz et al.; licensee BioMed Central Ltd.


Barbosa Jr. J.R.,Federal University of Santa Catarina | Sigwalt R.A.,Whirlpool Corp.
International Journal of Refrigeration | Year: 2012

The air-side thermal-hydraulic performance of spiral wire-on-tube condensers is investigated experimentally in this paper. Sixteen prototypes have been manufactured and tested in an open-loop wind tunnel calorimeter. The influence of the following geometric parameters has been evaluated: the number of tube passes, the radial and longitudinal tube spacings and the wire spacing. Measurements of the air-side thermal conductance and pressure drop were carried out for air flow rates ranging from 70 to 220 m 3 h -1. The data were correlated using empirical relationships for the Colburn j-factor and the Darcy friction factor. The agreement with the experimental data presented RMS deviations of 0.9% for the air-side heat transfer and 1.3% for the frictional pressure drop dimensionless parameters. A quantitative analysis based on the core volume goodness factors for heat transfer and pressure drop is presented to provide the most viable configuration from the point of view of application in a refrigerator. © 2012 Elsevier Ltd and IIR. All rights reserved.


Pereima R.S.,Federal University of Santa Catarina
Revista brasileira de enfermagem | Year: 2010

The article offers a reflection of blood donation in an hemocenter of Santa Catarina, with a mechanic and organic solidarity approach. It discuss the way of life in contemporary globalization and the cult of speed in a context pervaded by uncertainties and adversities. People live in a fast world, making social interaction difficult, contributing to the weakening of values and attitudes that could improve the quality of life. Considering the difficulties of everyday contemporary society, concerning Brazilian hemotherapy history on blood donation, there is a perception that attitudes and values, such as solidarity, have been modifying in subtle ways with a background of current events. It searches for understanding of blood donation as mechanic and organic solidarity.


Hayashi L.,Federal University of Santa Catarina | Reis R.P.,Institute Pesquisas Jardim Botanico Do Rio Of Janeiro
Brazilian Journal of Pharmacognosy | Year: 2012

Kappaphycus alvarezii (Rhodophyta, Gigartinales) is a red algae widely cultivated as the main source of raw material for the carrageenan industry. This hydrocolloid is normally used in the food industry as a gelling and stabilizing agent. The facility of its commercial farming based on vegetative propagation promoted the success of the aquaculture of this macroalgae that consequently stimulated studies focusing on new potential uses of this resource. This work presents a brief review of the studies related to K. alvarezii cultivation in southern and southeastern Brazil, the latest discoveries in the world concerning pharmacological studies with this species and the advantages of the use of carrageenan as a source of dietary fiber, cholesterol reducer, and antioxidant, anti-viral and anti-cancer compounds, as well as the effects in hemagglutination activity.


De Lima R.C.R.,Santa Catarina State University | Avancini S.S.,Federal University of Santa Catarina | Providencia C.,University of Coimbra
Physical Review C - Nuclear Physics | Year: 2013

The effect of strong magnetic fields on the properties of the pasta structure is calculated within a Thomas-Fermi approach using relativistic mean-field models to modulate stellar matter. It is shown how quantities such as the size of the clusters and Wigner-Seitz cells, the surface tension, and the transition between configurations are affected. It is expected that these effects may give rise to large stresses in the pasta phase if the local magnetic field suffers fluctuations. © 2013 American Physical Society.


Klanovicz J.,Federal University of Santa Catarina
Historia, Ciencias, Saude - Manguinhos | Year: 2010

The article explores the links between the controversial apprehension of contaminated apples in southern Brazil in 1989 and the reactions of the apple industry to press reports on the use of pesticides in Brazilian orchards. The issue is framed within a broader analysis of the notions of toxicity and 'danger' surrounding the consumption of healthier food and the idea of 'food security,' notions that have begun taking hold in public and private life. It is argued that apple growers' responses to the problem can be better understood through a historical reading of the interactions between the biology of the apple tree, the agroecology of this monoculture, and the structures, actors, and discourses of the human and non-human groups in Brazil's apple-producing region.


Heidemann I.T.S.B.,Federal University of Santa Catarina | Almeida M.C.P.,University of Sao Paulo
Public Health Nursing | Year: 2011

Objective: The study analyzes the possibility of incorporating health promotion measures into the work processes of Family Health Program teams at a primary health care clinic in Brazil. Design and Sample: We used the participatory research concept developed in 1968 by Freire. The study sample comprised the end-users of the health care system, together with 3 multidisciplinary teams. A total of 77 health care users and 55 health professionals participated in the study. Measures: Culture circles composed of health care professionals, and users from different areas investigated generative topics, encoded/decoded topics, and engaged in critical probing for clarification. Topics affecting quality of life and health were heuristically evaluated. Results: Although most topics were related to changing the focus of health care facilities, some were related to subsidizing community-based interventions, improving environmental strategies, individual skills, and public policies. Incorporating the novel health promotion measures and creating an expanded full-treatment clinic are important steps toward that goal. Conclusions: Topics that can stimulate dialogue among the members of the culture circles include creating an environment of closer cultural contact, with repercussions for work processes, family health models, and general health models, as well as the inclusion of social aspects in the decision-making processes related to health issues that affect the living conditions of the population. © 2010 Wiley Periodicals, Inc.


von Keyserlingk M.A.G.,University of British Columbia | Hotzel M.J.,Federal University of Santa Catarina
Journal of Agricultural and Environmental Ethics | Year: 2014

Over the last decade many emerging economies, and in particular Brazil, have established themselves as major players in global food animal production. Within these countries much of the increase in food animal production has been achieved by the adoption of intensive housing systems similar to those found in most industrialized countries. However, it is now well established that many of these systems are associated with numerous welfare problems, particularly with respect to restriction of movement. Previous work has shown that people living in industrialized’ countries broadly support farm animal welfare reform, and that similar criticisms may be voiced from citizens living in developing countries as they become more aware of confinement housing and potentially contentious husbandry practices. Given the developments that have taken place in other countries, there are lessons that could be learned and applied by emerging economies that would undoubtedly ease or prevent the challenges observed in other countries. Thus, we briefly describe the vehicles used by different countries when addressing animal welfare that may provide insights into identifying possible challenges and potential solutions for Brazil and other emerging economies. Where available we review the associated science and identify gaps where more research is needed. We conclude by providing a possible roadmap on how farm animal welfare reform may be addressed in emerging countries. Solutions will need to be tailored, culturally relevant, and science must play a key role in supporting animal welfare reform in the emerging countries. © 2014, Springer Science+Business Media Dordrecht.


The study tried to understand the meaning of hospitalization for children and teenagers with chronic diseases substantiated on Symbolic Interactionism and developed from the qualitative Assistential Converging Research whose participants were a child and three teenagers. Data collection took place through a nursing interaction process, participating observation, sensible listening and child drawing. During the analysis, the meaning of hospitalization was expressed as being ill, away from home, feeling pain, sadness, suffering, wishing to cry, nervousness, aggressiveness and losing freedom. It was also understood as treatment, cure, support, friends, reciprocity with nature and "pleasant experiences" through care, passion, love, happiness and games. The participants' ability to show their view of the situation in which they are inserted was highlighted in their drawings, imbued with meanings and life lessons.


Mazo G.Z.,Santa Catarina State University | Benedetti T.R.B.,Federal University of Santa Catarina
Revista Brasileira de Cineantropometria e Desempenho Humano | Year: 2010

The International Physical Activity Questionnaire (IPAQ) estimates the weekly energy expenditure for physical activities (PA). This instrument was validated for use with Brazilian older adults. The need to adapt the structure and application of the IPAQ arose from the difficulties of older adults to correctly measure the number of days, time and intensity of PA (domains) during a normal week and the difficulties encountered by the interviewers in field research. The adapted IPAQ consists of five domains and 15 questions and is applied by interview because of the low educational level of Brazilian older adults. The instrument is applied in its long form to permit better discrimination of PA in each domain and refers to a normal week to help recall morning, afternoon and evening activities. In addition, it includes details about mild, moderate and vigorous intensity. The training of the interviewers is fundamental. The report of the IPAQ adapted for older adults should be delivered in minutes per week and should use the classification active (≤ 150 min/week). The IPAQ adapted for older adults is an international instrument that is valid for the Brazilian elderly population. The instrument is a noninvasive easily applied method of low cost that reaches large population groups, among other advantages.


This article refers to the research discussion based on methodology of content analysis, which aims at making explicit the horizon of rationality of the services provided for alcohol users and other drugs in the Great Florianópolis region, to contribute to the establishment of qualitative parameters in the evaluation of health services. It was verified that there is a hegemonic conception about the drugs dependence phenomenon as well as the way to intervene in this phenomenon, synthesis of different and, sometimes, contradictory rationalities. The model of this conception is based on the notion of disease, on the pursue for abstinence, on the struggle to control de addiction, operating medical-therapeutic and moral apparatus. On the basis of this conception, there is a subjectivist, moralist and psychopathologizing perspective, constituting a historical and not very critical view of the social production around the use of drugs, grounded on a rationality of metaphysical predominance, even when blended with other rationalities such as the scientific. In this article we will discuss the importance of correlating the "horizon of rationality" in the health services with the problematic of effectiveness and efficiency of treatments on the area of drugs dependency.


Cupuassu (Theobroma grandiflorum), a specie native to Amazonia, has been planted commercially in Brazil to satisfy the demand for the flavorful juice obtained from the pulp around its seeds. The trees are notorious for low and irregular fruit production. Data gathered over two seasons from trees in a germplasm collection in Pará, Brazil, showed that some of them fruited more regularly than others. Differences in fruit production correlated to differences in flower production. Tree-to-tree variation in flower production, fruit production, and consistency of both over time suggest considerable scope for improving yields by selection. Hand pollinations resulted in a much higher frequency of fruit set than open pollinations, indicating that lack of effective pollination is also a reason for low yield. However, attempts to increase the level of effective pollination are handicapped by low knowledge about the pollinators of cupuassu and their behavior.


It is an experience report developed next to nurses of a public hospital of Florianópolis-SC, about pain measurement of cancer patient in palliative cares. A total of six nurses had participated of six meeting distributed at three educative moments of this practical. The analysis of undertaken dialogue evidenced that, for the nurses, measurable and objective data are not only enough to measure pain. According to them, it is imperative consider biopsicosociais aspects, valuing integrally the pain that the patient relates. The concluding nurses detach that she has necessity to construct a pain measurement systematization to allow strengthens the importance of pain control to base the practical one, make possible the register of information and the continued education.


That was a convergent-care study, carried out in a maternity ward in the Southern Region of Brazil from April to May 2009, with the purpose to comprehend the meanings of premature mother-child skin-to-skin contact and relevant nursing contributions. Data were collected through participant observation and interviews involving nine mothers. Four categories were identified: a) predelivery orientation surrounding premature mother-child skin-to-skin contact; b) establishing premature mother-child skin-to-skin contact; c) meanings of premature mother-child skin-to-skin contact for the mother; and d) nursing contributions in establishing premature mother-child skin-to-skin contact. It was concluded that the meanings of premature mother-child skin-to-skin contact attributed by these mothers is positive, and that nursing's contribution in establishing such contact is significant.


This article presents some guidelines for organizing the working process in Primary Health Care (PHC) and Family Health Strategy (FHS) concerning the challenges of providing access and balancing the everyday healthcare services activities which includes health promotion and prevention of diseases, as well as access for those suffering ill-health. Firstly, it addresses some specific ideas about the importance of access to the quality of the health care services, followed by a brief critique - based on Geoffrey Rose’s concepts - to the high-risk preventive strategy that has had high impact on health care organizational routines. Secondly, it contextualizes health promotion and its relations to individual health care in PHC/FHS, discussing the synergic potential of care and health promotion in their individual and collective dimensions to transcend the biomedical-mechanistic model. Finally, based on the above topics and concerning their operational consequences, as well as using a concrete example, it outlines general guidelines for organizing the working process and the agenda of doctors and nurses in the FHS, in order to facilitate both balance and synergy between access to health care and prevention/promotion, aiming to strengthen the FHS as local coordinator of care and main entrance of the Brazilian National Health System. © 2015, UNIV SAOPAULO. All rights reserved.


De Figueiredo Locks G.,Federal University of Santa Catarina
Revista Brasileira de Anestesiologia | Year: 2012

Background and objectives: Shivering is a cause of discomfort and dissatisfaction in patients undergoing cesarean section. The objective of this study paper was to assess the impact of intrathecal administration of sufentanil on the incidence of shivering after cesarean section. Method: In a prospective blinded, randomized clinical trial, pregnant women undergoing cesarean section under spinal anesthesia were enrolled. Pregnant women in labor, febrile, obese, with pregnancy-induced hypertension, anesthetic block failure or surgical complications were excluded. Patients were randomly assigned to two groups. In Group I, 10. mg of 0.5% hyperbaric bupivacaine combined with 80. mcg of morphine and 2.5. mcg of sufentanil were administered. In Group II, 10. mg of 0.5% hyperbaric bupivacaine combined with 80. mcg of morphine were administered. In the post-anesthesia care unit, patients were evaluated for signs of shivering by an investigator blinded to the patient's group allocation. Results: The sample consisted of 80 patients. In both groups there was a decrease in axillary temperature of patients after cesarean section (p. < 0.001). This decrease was not different between groups (p. < 0.21). In Group I, the incidence of tremor was 32.5% (13/40) and in Group II it was 62.5% (25/40) (p. < 0.007); RR 0.53 (CI 95% 0.32-0.87). Conclusions: It has been suggested that the addition of sufentanil to hyperbaric bupivacaine and morphine during spinal anesthesia for cesarean section provides a decrease in the incidence of shivering in the immediate postoperative period. © 2012 Elsevier Editora Ltda.


Barros C.C.,Federal University of Santa Catarina | Hama Y.,University of Sao Paulo
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2011

Experiments at RHIC have shown that in 200 GeV Au-Au collisions, the Λ and ̄Λ- hyperons are produced with very small polarizations (Abelev et al., 2007) [1], almost consistent with zero. These results can be understood in terms of a model that we proposed (Barros and Hama, 2008) [2]. In this Letter, we show how this model may be applied in such collisions, and also will discuss the relation of our results with other models, in order to explain the experimental data. © 2011 Elsevier B.V.


Alloy M.D.,University Federal da Fronteira Sul | Menezes D.P.,Federal University of Santa Catarina
Physical Review C - Nuclear Physics | Year: 2011

In this paper, we calculate the diffusion coefficients that are related to the neutrino opacities considering the formation of nuclear pasta and homogeneous matter at low densities. Our results show that the mean-free paths are significantly altered by the presence of nuclear pasta in stellar matter when compared with the results obtained with homogeneous matter. These differences in neutrino opacities certainly influence the Kelvin-Helmholtz phase of protoneutron stars and consequently the results of supernova explosion simulations. © 2011 American Physical Society.


Favaro C.E.,Federal University of Santa Catarina
Historia, Ciencias, Saude - Manguinhos | Year: 2010

During their settlement of the so-called Old Italian Colonies of Rio Grande do Sul, immigrants constructed a set of positive values that were to serve as an emotional support and a means of outside communication. When women immigrants embroidered images and sayings on wall hangings or kitchen towels made of rustic fabric, they helped nourish the dream of a better life, sought by all and achieved by some. The objects crafted by these twentiethcentury Penelopes bear witness to a way of doing, thinking, and acting. Local museums and exhibits have fostered the recovery of old-time embroidery techniques and themes; sold at open-air markets and regional festivals, these products represent income for women whose age excludes them from the formal labor market.


Taneja I.J.,Federal University of Santa Catarina
Applied Mathematics and Information Sciences | Year: 2013

In this paper we have considered an inequality having 11 divergence measures. Out of them three are logarithmic such as Jeffryes-Kullback-Leiber [4] [5] J-divergence. Burbea-Rao [1] Jensen-Shannon divergence and Taneja [7] arithmetic-geometric mean divergence. The other three are non-logarithmic such as Hellinger discrimination, symmetric χ2divergence, and triangular discrimination. Three more are considered are due to mean divergences. Pranesh and Johnson [6] and Jain and Srivastava [3] studied different kind of divergence measures.We have considered measures arising due to differences of single inequality having 11 divergence measures in terms of a sequence. Based on these differences we have obtained many inequalities. These inequalities are kept as nested or sequential forms. Some reverse inequalities and equivalent versions are also studied. © 2013 NSP. Natural Sciences Publishing Cor.


De Cezaro A.,Grande Rio University | Leitao A.,Federal University of Santa Catarina | Tai X.-C.,University of Bergen
Inverse Problems | Year: 2013

We investigate level-set-type methods for solving ill-posed problems with discontinuous (piecewise constant) coefficients. The goal is to identify the level sets as well as the level values of an unknown parameter function on a model described by a nonlinear ill-posed operator equation. The PCLS approach is used here to parametrize the solution of a given operator equation in terms of a L2 level-set function, i.e. the level-set function itself is assumed to be a piecewise constant function. Two distinct methods are proposed for computing stable solutions of the resulting ill-posed problem: the first is based on Tikhonov regularization, while the second is based on the augmented Lagrangian approach with total variation penalization. Classical regularization results (Engl H W et al 1996 Mathematics and its Applications (Dordrecht: Kluwer)) are derived for the Tikhonov method. On the other hand, for the augmented Lagrangian method, we succeed in proving the existence of (generalized) Lagrangian multipliers in the sense of (Rockafellar R T and Wets R J-B 1998 Grundlehren der Mathematischen Wissenschaften (Berlin: Springer)). Numerical experiments are performed for a 2D inverse potential problem (Hettlich F and Rundell W 1996 Inverse Problems 12 251-66), demonstrating the capabilities of both methods for solving this ill-posed problem in a stable way (complicated inclusions are recovered without any a priori geometrical information on the unknown parameter). © 2013 IOP Publishing Ltd.


Caponi S.,Federal University of Santa Catarina
Historia, Ciencias, Saude - Manguinhos | Year: 2010

When Kraepelin laid the foundations of what we now understand as psychiatry, he was faithful to the nineteenth-century hygienist's penchant for approaching social problems in terms of medical categories. With Kraepelin's writings on the issue of degeneration as a backdrop, the article analyzes how the methodology he introduced for researching psychiatric illnesses is indebted to Morel's theory of degeneration. The article explores not only Kraepelin's concern with defining a classification of mental pathologies just as well grounded as the classifications of biological pathologies, but also his use of comparative statistics and his explanations of morbid heredity.


Martins M.L.,Federal University of Santa Catarina | Shoemaker C.A.,U.S. Department of Agriculture | Xu D.,U.S. Department of Agriculture | Klesius P.H.,U.S. Department of Agriculture
Aquaculture | Year: 2011

Limited information is available on vaccine performance in parasitized fish. The objective of this study was to determine if parasitism of fish affected vaccine efficacy. Antibody level, hematology and survival of Nile tilapia vaccinated with a modified S. iniae bacterin were compared among non-parasitized fish, fish parasitized by Trichodina heterodentata and Gyrodactylus cichlidarum, and fish parasitized by T. heterodentata, G. cichlidarum and Ichthyophthirius multifiliis (Ich). Among vaccinated fish, fish free from parasites (Trichodina, Gyrodactylus and Ich) had the highest antibody level (0.43, SE = 0.14). Significantly (p < 0.05) lower anti- S. iniae antibody was noted in parasitized vaccinated fish (0.30, SE = 0.08). Among the vaccinated treatments, fish parasitized by Trichodina, Gyrodactylus and Ich showed the lowest survival (80.0%, SE = 10.0), significantly (p < 0.05) lower than vaccinated fish free from parasites (97.5%, SE = 2.5) or parasitized by Trichodina and Gyrodactylus (95.0%, SE = 5.0). Following challenge with S. iniae, non-vaccinated fish free from parasites showed the higher survival (47.5%, SE = 2.5) than non-vaccinated fish parasitized by Trichodina and Gyrodactylus (37.5%, SE = 2.5). Non-vaccinated fish parasitized by all 3 parasites showed the lowest survival (27.5%, SE = 2.5) post challenge. Relative percent survival (RPS) demonstrated a decrease in vaccine performance for the group of fish that were parasitized with Trichodina and Gyrodactylus and Ich. RPS was 72% compared to 95 and 92%, respectively, in the other vaccinated treatments following challenge. This study demonstrated a reduction in vaccine performance in parasitized tilapia and highlights the importance of monitoring or controlling parasite levels in the aquaculture setting to optimize vaccine efficacy. © 2011 Elsevier B.V.


Marcelino L.F.,University of South Santa Catarina | Patricio Z.M.,Federal University of Santa Catarina
Ciencia e Saude Coletiva | Year: 2011

The high incidence of obese people submitted to bariatric surgery as treatment for obesity has prompted the need to carry out a survey to ascertain the repercussions of this treatment on the health of a group of individuals subjected to such surgery. Data were collected via in-depth interviews, focusing on identification of the background to the situation that led to the decision to submit to obesity surgery and the quality of daily life after treatment. The analysis showed that the constant difficulties and frustrations in combating obesity and the expectation of the definitive cure led to the decision to submit to surgery in that group. However, life after surgery was characterized as a continuous process of challenges with further hurdles in order to learn how to live again on a day-to-day basis and return to full health. This also presents challenges for the health team as it involves greater investment in public health, improvement strategies for prevention and control of obesity of the population and comprehensive care actions for those individuals. Such complexity requires interdisciplinary expertise with an approach in line with the emotional and socio-cultural issues of this population group.


Ritter D.E.,Federal University of Santa Catarina
Dental Press Journal of Orthodontics | Year: 2014

This article reports the orthodontic diagnosis and treatment planning carried out with a 14-year and 5-month-old female patient with esthetic and functional complaints. She presented an Angle Class I malocclusion, anterior crossbiteand severe crowding in both maxillary and mandibular arches, in addition to a lightly concave straight facial profile. Orthodontic treatment did not require extraction. Crossbite was corrected by protrusion of upper teeth, which contributed to alignment and leveling of teeth, in addition to improving the patient's facial profile. The case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as a requirement for the BBO certification. © 2014 Dental Press Journal of Orthodontics.


Paduani C.,Federal University of Santa Catarina
International Journal of Hydrogen Energy | Year: 2014

The structure and electronic properties of sodium and magnesium aluminohydrides (alanates) and borohydrides (boranates) are systematically investigated in first-principles calculations using density functional theory. A study of the result of successive attachments of AlH4 and BH4 complexes to Na and Mg reveals superhalogen behavior for the clusters Na(AlH4)2, Na(BH4)2, Mg(AlH4)3 and Mg(BH4)3, whose electron affinities are 4.93 eV, 5.07 eV, 5.20 eV and 5.13 eV, respectively, which far exceed that of chlorine (3.6 eV). The energetics of the H-removal from these clusters is also investigated and the results show that the hydrogen release is substantially less energy demanding for the superhalogen moieties. The energy cost for H-removal decreases from 3.72 eV in Na(AlH4) to 0.49 eV in Na(AlH4)2, and from 4.63 eV in Mg(BH4)2 to 0.37 eV in Mg(BH4)3. For the closed shell clusters, the alanates have superior performance with respect to the release of hydrogen as compared with the boranates. For the superhalogens, the energy cost for H-removal from Na(AlH4)2 is half of that one for the Na(BH4)2 cluster, whereas for the Mg clusters Mg(AlH4)3 and Mg(BH4)3 it is nearly equivalent (0.41 eV and 0.37 eV, respectively). This arises from the formation of an insurgent dimerized unit where the H atoms exhibit considerable loss of bonding charge. © 2014 Hydrogen Energy Publications, LLC.


Bottion A.J.B.,Federal Center for Technological Education of Minas Gerais | Barbi I.,Federal University of Santa Catarina
IEEE Transactions on Industrial Electronics | Year: 2015

This paper proposes a modular isolated dc-dc converter, based on the input-series and output-series association of the full-bridge PWM dc-dc converter with capacitive filter. The main attribute of the proposed architecture is its ability to provide self-balance of the input and output voltages across the individual converters, without voltage loop control scheme, both in the steady-state and transient operations. Circuit operation, theoretical analysis, and modeling are included in this paper, along with experimental results taken from a laboratory prototype with four modules, 1600-Vdc total input voltage, 1600-Vdc total output voltage, 4-kW output power, and 40-kHz switching frequency. Possible applications include high-voltage power supplies, solid-state transformers, dc current distribution systems, and renewable electric energy systems. © 2015 IEEE.


Dobigeon N.,National Polytechnic Institute of Toulouse | Tourneret J.-Y.,National Polytechnic Institute of Toulouse | Richard C.,University of Nice Sophia Antipolis | Bermudez J.C.M.,Federal University of Santa Catarina | And 2 more authors.
IEEE Signal Processing Magazine | Year: 2014

When considering the problem of unmixing hyperspectral images, most of the literature in the geoscience and image processing areas relies on the widely used linear mixing model (LMM). However, the LMM may be not valid, and other nonlinear models need to be considered, for instance, when there are multiscattering effects or intimate interactions. Consequently, over the last few years, several significant contributions have been proposed to overcome the limitations inherent in the LMM. In this article, we present an overview of recent advances in nonlinear unmixing modeling. © 1991-2012 IEEE.


Waterkemper R.,Federal University of Santa Catarina
Revista gaúcha de enfermagem / EENFUFRGS | Year: 2010

The purpose of this study is to reveal nurses' ideas and contributions on the assessment of cancer patients' pain in palliative care through a proposal of work education based on Paul Freire's problematizing education theory. We used Juan Charles Maguerez's "problematization arc" as a strategy for data collection. The study included six nurses. The results pointed to three categories: (1) the meaning of pain, (2) the way pain assessment is practiced by nurses and (3) contributions to care. Cancer pain is a total pain. It exceeds the physical dimension of disease and extends to psychological and social dimensions. The deployment of systematic pain care routines, enclosed in the systematization of nursing care makes it possible to better redirect the actions, therefore achieving a most complete and effective pain management.


Chen H.,University of Sydney | Li Y.,University of Sydney | Rebelatto J.L.,Federal University of Technology of Parana | Uchoa-Filho B.F.,Federal University of Santa Catarina | Vucetic B.,University of Sydney
IEEE Transactions on Signal Processing | Year: 2015

In this paper, we consider a wireless-powered cooperative communication network consisting of one hybrid access-point (AP), one source, and one relay. In contrast to conventional cooperative networks, the source and relay in the considered network have no embedded energy supply. They need to rely on the energy harvested from the signals broadcasted by the AP for their cooperative information transmission. Based on this three-node reference model, we propose a harvest-then-cooperate (HTC) protocol, in which the source and relay harvest energy from the AP in the downlink and work cooperatively in the uplink for the source's information transmission. Considering a delay-limited transmission mode, the approximate closed-form expression for the average throughput of the proposed protocol is derived over Rayleigh fading channels. Subsequently, this analysis is extended to the multi-relay scenario, where the approximate throughput of the HTC protocol with two popular relay selection schemes is derived. The asymptotic analyses for the throughput performance of the considered schemes at high signal-to-noise radio are also provided. All theoretical results are validated by numerical simulations. The impacts of the system parameters, such as time allocation, relay number, and relay position, on the throughput performance are extensively investigated. © 1991-2012 IEEE.


Sumar R.R.,Federal University of Technology | Coelho A.A.R.,Federal University of Santa Catarina | Dos Santos Coelho L.,Pontifical Catholic University of Parana
Information Sciences | Year: 2010

Despite the popularity of PID (Proportional-Integral-Derivative) controllers, their tuning aspect continues to present challenges for researches and plant operators. Various control design methodologies have been proposed in the literature, such as auto-tuning, self-tuning, and pattern recognition. The main drawback of these methodologies in the industrial environment is the number of tuning parameters to be selected. In this paper, the design of a PID controller, based on the universal model of the plant, is derived, in which there is only one parameter to be tuned. This is an attractive feature from the viewpoint of plant operators. Fuzzy and neural approaches - bio-inspired methods in the field of computational intelligence - are used to design and assess the efficiency of the PID controller design based on differential evolution optimization in nonlinear plants. The numerical results presented herein indicate that the proposed bio-inspired design is effective for the nonlinear control of nonlinear plants. © 2010 Elsevier Inc. All rights reserved.


Gallegos E.A.,Federal University of Santa Catarina | Senise C.R.,Federal University of Pampa | Da Silva A.J.,University of Sao Paulo
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2013

We deform the well-known three-dimensional N=1 Wess-Zumino model by adding higher derivative operators (Lee-Wick operators) to its action. The effects of these operators are investigated both at the classical and quantum levels. © 2013 American Physical Society.


dos Santos J.L.,Federal University of Santa Catarina
Revista gaúcha de enfermagem / EENFUFRGS | Year: 2012

The purpose of this study is to analyze the risks and vulnerability found in professional healthcare and the safe practices adopted based on academic research in the field of healthcare and nursing, by means of an integrative review. The articles were found in the LILACS and SCIELO databases,from the years 2005-2010, in a search for the descriptors vulnerability, risk, and occupational and personal health risks, establishing a sample of 21 articles. In basic healthcare, risks and vulnerabilities are related to the lack of resources needed for work, physical violence and emotional strain. In a hospital context, the problems are related to accidents with biological materials caused by improper use and failure to adopt protective measures, as well as excessive work and self-confidence. The importance of implementing public policies in worker health to improve working conditions and provide greater satisfaction and professional awareness is emphasized.


Romanha A.J.,Federal University of Santa Catarina
Journal of Antimicrobial Chemotherapy | Year: 2014

Objectives: Toevaluate in vitro interactions between paromomycin sulphateandthe antileishmanial drugs meglumine antimoniate, amphotericin B, miltefosine and azithromycin against intracellular Leishmania (Leishmania) infantum chagasi, Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis amastigotes in peritoneal mouse macrophages. Methods: First, drug susceptibilitywas assessed in 3, 5 and 7 day assays, followed by drug interaction assays with a modified fixed-ratio method. An overall mean sum fractional inhibitory concentration (∑FIC) was calculated for each combination and each Leishmania species. The nature of the interactions was classified as synergistic if the mean ∑FIC was ≤0.5, indifferent if the mean ∑FIC was <0.5-4.0 and antagonistic if the mean ∑FIC was >4.0. Results: In vitro synergismwas observed for the combinations of paromomycin plus miltefosine [at50% and 90% inhibitory concentrations (IC50 and IC90, respectively)] and paromomycin plus amphotericin B (at the IC90 level) against L. (L.) amazonensis, paromomycin plus meglumine antimoniate (at the IC50 and IC90 levels) and paromomycin plus amphotericin B (at the IC50 level) against L. (V.) braziliensis, and paromomycin plus miltefosine, paromomycin plus amphotericin B (both at the IC90 level) and paromomycin plus azithromycin (at the IC50 level) against L. (L) infantum chagasi. Conclusions: This work provides a preclinical dataset that supports future studies on multidrug treatment schedules against NewWorld leishmaniasis. © The Author 2013. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved.


Yacubian E.M.,University of Sao Paulo | Wolf P.,Danish Epilepsy Center | Wolf P.,Federal University of Santa Catarina
Seizure | Year: 2015

Purpose There is increasing awareness that reflex epileptic mechanisms provide unique insight into ictogenesis in human epilepsies. Among the complex triggers of seizures, this review considers orofacial reflex myocloni (ORM) from the aspects of history and delineation, clinical and electroencephalographic presentation, syndromatic relations, prevalence, mechanisms of ictogenesis and nosological implications, treatment and prognosis. Methods We reviewed all published articles and case reports on ORM in order to clarify clinical and electroencephalographic findings, treatment and outcome. Results ORM, besides Reading Epilepsy (RE), is closely related to idiopathic generalized epilepsies especially Juvenile Myoclonic Epilepsy (JME) where hyperexcitability of the network supporting linguistic communication seems to provide the precondition for eliciting reflex myocloni in the perioral muscles active in the precipitating task. Conclusion The conclusions on ictogenesis derived from ORM support the concept of both, RE and JME, as system disorders of the brain. © 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.


Mansur D.S.,Federal University of Santa Catarina | Smith G.L.,Tennis Court Road | Ferguson B.J.,Tennis Court Road
Microbes and Infection | Year: 2014

Recent years have seen a great advance in knowledge of how a host senses infection. Nucleic acids, as a common denominator to all pathogens, are at the centre of several of the sensing pathways, especially those involved with the recognition of viruses. In this review we discuss the current knowledge on how intracellular DNA is sensed by the mammalian host. © 2014.


Alberto E.E.,Federal University of Santa Maria | Alberto E.E.,State University of New York at Buffalo | Braga A.L.,Federal University of Santa Catarina | Detty M.R.,State University of New York at Buffalo
Tetrahedron | Year: 2012

The design and synthesis of imidazolium-containing diselenides 4a-c is described. The introduction of the N-methylimidazolium group gives freely soluble compounds in water, unlike the majority of common organic diselenides. Catalytic amounts of 4a-c effectively promote bromination of organic substrates using a safe and inexpensive NaBr/H 2O 2 system in water. Kinetics experiments revealed that the bromination of 4-pentenoic acid has a first-order dependence with respect to both NaBr and H 2O 2 concentrations The rate of reaction was also sensitive to the pH of the solution. Preparative reactions showed that, compared to 4a, diphenyl diselenide 5 was a poor catalyst and the ionic liquid 1-benzyl-3-methylimidazolium bromide 6 showed no catalytic activity with H 2O 2 indicating synergy from the combined functionality. © 2012 Elsevier Ltd. All rights reserved.


This qualitative study sought to analyze the meanings attributed to domestic violence against the elderly by professionals in Primary Healthcare. A total of 10 health professionals from different backgrounds from a renowned health unit for care of the elderly took part, and the data was collected through semi-structured interviews. Taking the Grounded Theory as a benchmark, the data were integrated and organized into categories, subcategories and elements of analysis. The results revealed the participants' expectation that the family acts as support and protection for the elderly and that domestic violence violates this principle. The significance of abuse of the elder was found to be grounded in the idea "of the frail and dependent elderly person," limiting the viewing of cases that do not fit this profile.


This article addresses conceptual and methodological aspects of the relations between discrimination and health from an epidemiological perspective. Definitions of discrimination and related constructs are reviewed, and the main theories underlying their association with health are presented. Scales developed to assess discrimination are discussed, in conjunction with a new instrument, devised to operationalize the concept in Brazilian epidemiological surveys. As a relatively unpredictable and uncontrollable source of psychosocial stress, discrimination has been consistently associated with adverse health outcomes and behaviors, particularly mental disorders, smoking, and alcohol use. However, progress in the area depends partly on dealing with aspects related to the assessment of the phenomenon, such as the definition of a construct map and simultaneous measurement of different types of discrimination. Research involving these aspects will enhance our understanding of discrimination and its health consequences, thus increasing our ability to reduce its social occurrence.


Foletto E.L.,Federal University of Santa Maria | Jahn S.L.,Federal University of Santa Maria | De Fatima Peralta Muniz Moreira R.,Federal University of Santa Catarina
Journal of Applied Electrochemistry | Year: 2010

Zinc stannate (Zn2SnO4) powder was prepared by a hydrothermal process at 200 °C for 12 h. The material was characterized by X-ray-diffraction (XRD) and N2 adsorption-desorption isotherms. The synthesized sample presented a pure phase, an average nanocrystal size of about 19 nm, a surface area (BET) of about 41.8 m2 g-1 and total pore volume of about 0.19 cm3 g-1. Its photocatalytic activity was tested by the degradation of the leather azo-dye, Direct Black 38, in aqueous solution under UV irradiation. Adsorption kinetic data showed that the pseudo-second-order model was the most appropriate for the dye studied. Adsorption onto the Zn2SnO4 surface followed the Langmuir isotherm. The catalyst showed highly photocatalytic activity towards degradation of the dye, almost equal to that of the TiO2-P25 Degussa photocatalyst. The results indicate that Zn2SnO4 could be employed for the removal of dyes from wastewaters. © 2009 Springer Science+Business Media B.V.


Brunelli J.C.,Federal University of Santa Catarina | Sakovich S.,National Academy of Sciences of Belarus
Journal of Mathematical Physics | Year: 2013

We obtain the bi-Hamiltonian structure for some of the two-component short pulse equations proposed in the literature to generalize the original short pulse equation when polarized pulses propagate in anisotropic media. © 2013 American Institute of Physics.


Louwaars N.P.,Wageningen University | De Boef W.S.,Federal University of Santa Catarina | De Boef W.S.,Wageningen University
Journal of Crop Improvement | Year: 2012

Public sector seed programs in most sub-Saharan African countries targeted the dissemination of quality seed of improved varieties in the 1970 and '80s, assuming that the informal seed system would disappear. The orientation in 1990s shifted toward withdrawal of the public sector, promoting privatization and liberalization of the seed market. The informal seed system remained dominant. Integrated seed sector development aims to better link informal and formal seed systems, and balance public and private sector involvement. It explores variation among seed value chains, with the aim of making seed programs and policies more coherent with farmers' practices and more effective at reaching food security. © 2012 Taylor and Francis Group, LLC.


Azevedo C.L.N.,University of Campinas | Bolfarine H.,University of Sao Paulo | Andrade D.F.,Federal University of Santa Catarina
Computational Statistics and Data Analysis | Year: 2011

Item response theory (IRT) comprises a set of statistical models which are useful in many fields, especially when there is interest in studying latent variables. These latent variables are directly considered in the Item Response Models (IRM) and they are usually called latent traits. A usual assumption for parameter estimation of the IRM, considering one group of examinees, is to assume that the latent traits are random variables which follow a standard normal distribution. However, many works suggest that this assumption does not apply in many cases. Furthermore, when this assumption does not hold, the parameter estimates tend to be biased and misleading inference can be obtained. Therefore, it is important to model the distribution of the latent traits properly. In this paper we present an alternative latent traits modeling based on the so-called skew-normal distribution; see Genton (2004). We used the centred parameterization, which was proposed by Azzalini (1985). This approach ensures the model identifiability as pointed out by Azevedo et al. (2009b). Also, a Metropolis-Hastings within Gibbs sampling (MHWGS) algorithm was built for parameter estimation by using an augmented data approach. A simulation study was performed in order to assess the parameter recovery in the proposed model and the estimation method, and the effect of the asymmetry level of the latent traits distribution on the parameter estimation. Also, a comparison of our approach with other estimation methods (which consider the assumption of symmetric normality for the latent traits distribution) was considered. The results indicated that our proposed algorithm recovers properly all parameters. Specifically, the greater the asymmetry level, the better the performance of our approach compared with other approaches, mainly in the presence of small sample sizes (number of examinees). Furthermore, we analyzed a real data set which presents indication of asymmetry concerning the latent traits distribution. The results obtained by using our approach confirmed the presence of strong negative asymmetry of the latent traits distribution. © 2010 Elsevier B.V. All rights reserved.


Alves J.A.,Federal University of Santa Catarina
Revista brasileira de reumatologia | Year: 2011

Some studies have reported that adding leflunomide (LEF) to the treatment of rheumatoid arthritis (RA) in patients who do not respond to methotrexate (MTX) improved efficacy but increased the risk of liver toxicity. This study aimed at assessing the incidence of liver toxicity in patients with active RA using the LEF and MTX combination therapy in comparison with that of patients on MTX monotherapy. Between February and September 2009, 97 consecutive patients followed up at the University Hospital of the Universidade Federal de Santa Catarina, Brazil, were enrolled. RA patients on MTX alone or using the LEF and MTX combination had their medical records systematically reviewed. The alanine/aspartate aminotransferase enzymes were retrospectively analyzed since the beginning of treatment with MTX or MTX plus LEF. Hepatotoxicity was defined as an increase of at least two-fold the upper limits of normal of the liver enzymes. 71 RA patients were included in the study: 36.6% were using 20-25 mg/week of MTX alone and 63.4% were using 20-25 mg/week of MTX plus 20 mg/day of LEF. Of the patients on the combination therapy, 11.1% had abnormal levels of liver enzymes versus 11.5% of the patients on monotherapy (P = 1.0). Abnormal aminotransferase levels have been seen with both MTX and LEF monotherapies in patients with RA. In our study, no difference was found between the percentages of aminotransferase elevations of patients being treated with MTX alone or in combination with LEF. The combination of MTX and LEF in RA patients is generally safe and well tolerated.


de Vasconcelos F.A.G.,Federal University of Santa Catarina | Filho M.B.,Institute Medicina
Ciencia e Saude Coletiva | Year: 2011

This paper aims to trace the history of the scientific field of Food and Nutrition in Public Health in Brazil (FNPH), trying to describe the contexts that allowed the construction, consolidation and redefinition of the field, to identify the Brazilian scientists who contributed to this process and address the scientific concepts or paradigms that guided the actions of these scientists. As methodological criteria of analysis three cross sections corresponding to contexts of history in this field were established: The first one covers the period from 1930 to 1963, the second one between 1964 and 1984 and the third one considers the period from 1985 to 2010. We conclude that the field of FNPH assumed the current configuration from the mid-1970's, within the so-called Brazilian health movement, whose main ideas were the achievement of health reform and the construction of the Unified Health System. We reaffirm the importance of multidisciplinary character and the premise of the important role of the field of FNPH in ensuring the human right to healthy food, a component of the set of conditions necessary for health promotion, disease prevention, surveillance and health recovery and improvement of quality of life for all Brazilians.


Dupin E.,French National Center for Scientific Research | Calloni G.W.,French National Center for Scientific Research | Calloni G.W.,Federal University of Santa Catarina | Le Douarin N.M.,French National Center for Scientific Research
Cell Cycle | Year: 2010

In the amniote embryo, the neural crest (NC) has the unique capacity to give rise to neuronal and glial cells in the peripheral nervous system (PNS), melanocytes and mesenchymal cells including those forming the head skeleton and connective tissues. In the trunk, mesenchymal cells are derived from the mesoderm. The question was raised whether the NC-derived head mesenchyme arises from a lineage separate from the neuralmelanocytic one, or if both skeletogenic and neural-melanocytic derivatives originate from a common putative stem cell in the early cephalic NC. We discuss here these issues and present experimental data that provide evidence for the multipotency of NC cells (NCC), focusing on those at the origin of the craniofacial skeleton. Recent work of in vitro clonal culture revealed that the vast majority (92% of clonogenic cells) of the cephalic quail NCC are capable to yield osteo-blasts together with neurones, glial cells and melanocytes. A common pluripotent progenitor for chondrocytes, osteocytes, neurones, glial cells, melanocytes and myofibroblasts has been identified and is present in the early cephalic NC at the frequency of 7 to 13% of clonogenic cells depending on the environmental conditions. Together with recent reports that multipotent NC-related progenitors persist in adult tissues in rodents and humans, these results reinforce a stem cell model for the generation and maintenance of NC-derived lineages during embryogenesis and in adult tissue homeostasis. © 2010 Landes Bioscience.


Castro L.B.,Federal University of Santa Catarina
Physical Review C - Nuclear Physics | Year: 2012

We address the behavior of the Dirac equation with scalar (S), vector (V), and tensor (U) interactions under the γ5 discrete chiral transformation. By using this transformation, in a simple way, we can obtain solutions for the Dirac equation with spin (Δ=VS=0) and pseudospin (Σ=V+S=0) symmetries, which includes a tensor interaction. As an application, the Dirac equation with scalar, vector, and tensor Cornell radial potentials is considered, and the correct solution to this problem is obtained. © 2012 American Physical Society.


Normey-Rico J.E.,Federal University of Santa Catarina | Garcia P.,Polytechnic University of Valencia | Gonzalez A.,Polytechnic University of Valencia
Journal of Process Control | Year: 2012

This paper focuses on the robust stability analysis of the filtered Smith predictor (FSP) dead-time compensator for uncertain processes with time-varying delays. For this purpose, a delay-dependent LMI-based condition is used to compute a maximum delay interval and tolerance to model uncertainties such that the closed-loop system remains stable. Some simulation results illustrate that the proposed controller gives larger delays intervals or better performance than similar approaches proposed in literature applied both to stable and unstable processes. © 2012 Elsevier Ltd. All rights reserved.


Giachini A.J.,Federal University of Santa Catarina | Castellano M.A.,U.S. Department of Agriculture
Mycotaxon | Year: 2011

Taxonomy of the Gomphales has been revisited by combining morphology and molecular data (DNA sequences) to provide a natural classification for the species of Gomphus sensu lato. Results indicate Gomphus s.l. to be non-monophyletic, leading to new combinations and the placement of its species into four genera: Gomphus sensu stricto (3 species), Gloeocantharellus (11 species), Phaeoclavulina (41 species), and Turbinellus (5 species). © 2011. Mycotaxon, Ltd.


Frazao P.,University of Sao Paulo | Peres M.A.,Federal University of Santa Catarina | Cury J.A.,University of Campinas
Revista de Saude Publica | Year: 2011

This paper aimed to analyze the fluoride concentration in drinking water, taking into account the balance between the benefits and risks to health, in order to produce scientific backing for the updating of the Brazilian legislation. Systematic reviews studies, official documents and meteorological data were examined. The temperatures in Brazilian state capitals indicate that fluoride levels should be between 0.6 and 0.9 mg F/l in order to prevent dental caries. Natural fluoride concentration of 1.5 mg F/l is tolerated for consumption in Brazil if there is no technology with an acceptable cost-benefit ratio for adjusting/removing the excess. Daily intake of water with a fluoride concentration > 0.9 mg F/l presents a risk to the dentition among children under the age of eight years, and consumers should be explicitly informed of this risk. In view of the expansion of the Brazilian water fluoridation program to regions with a typically tropical climate, Ordinance 635/75 relating to fluoride added to the public water supply should be revised.


Fadel L.M.,Federal University of Santa Catarina
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2014

This paper presents an experience-centered web design model. This model was constructed identifying a series of heuristics that characterize the quality of experience. This series was the start point to select a set of variables that could be used to design the user experience. Thus, user experience is designed using variables such as: challenge, focused attention and clear goals and feedback. These variables were analyzed in terms of the three dimensions of user experience which were established from the literature review: emotional, functional and aesthetics dimensions. This analysis was used to create a model for an experience-centered web design. In addition, this paper suggests that this model can be used in different applications of experience-centered design. © 2014 Springer International Publishing Switzerland.


Silva D.,Federal University of Santa Catarina
2012 International Symposium on Network Coding, NetCod 2012 | Year: 2012

This paper addresses the linear dependency problem that arises in random linear network coding (RLNC) when a small field size is used. We show that, by appropriate precoding with maximum-rank-distance (MRD) codes, the linear dependency problem can be virtually eliminated, even over a binary field. Besides simplifying operations at the intermediate nodes, decreasing the field size has the benefit of reducing the header overhead from coding coefficients, which comprises a large fraction of the total overhead for practical (short to moderate) packet lengths. Thus, for a moderate increase in decoding complexity, the total overhead of RLNC can be significantly reduced. The proposed scheme can be applied to any form of generation-based RLNC, including schemes that use overlapping generations. ©2012 IEEE.


Silva J.A.,Federal University of Santa Catarina
Nutrition and cancer | Year: 2012

Inflammation is a common feature in cancer. The presence and magnitude of the chronic systemic inflammatory responses may produce progressive nutritional decline. This study aims at investigating whether there are changes in inflammation markers and/or in nutritional status of patients with colorectal cancer undergoing chemotherapy who were supplemented with fish oil. The clinical trial was conducted with 23 patients randomly distributed in 2 groups. The supplemented group (SG) consumed 2 g of fish oil containing 600 milligrams of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) for 9 wk. Nutritional and inflammatory markers status was available, both at a baseline (M0), and after 9 wk of chemotherapy (M9) in the SG and in the nonsupplemented group (NSG). Statistical analysis was conducted with STATA 11.0 software. SG and NSG presented the same baseline characteristics (P > 0.05). Nutritional status indicators such as body mass index and body weight were modified only in the NSG when comparing baseline and M9, P = 0.03 and P = 0.01 respectively, whereas in SG these indicators did not vary. Patients supplemented with fish oil (SG) showed a clinically relevant decrease in the C-reactive protein/albumin relation (P = 0.005). Low doses of fish oil supplement can positively modulate the nutritional status and the C-reative protein/albumin ratio.


da Silveira S.J.,Federal University of Santa Catarina | Henrique de Oliveira F.,Santa Catarina State University
Journal of Urban Planning and Development | Year: 2014

Current scientific literature reinforces the observation that there has been an increase in frequent occurrences of floods in urban areas and emphasizes that the main reason for the increase of flooding is the reaction of the environment to the effects of anthropic action. Considering this scenario of flooding caused by man, this study aims to present a review of the literature on the influence of soil sealing, define sustainable allotment (SA) in line with the local behavior of the hydrological cycle, and propose the establishment of a technical requirement on the part of Brazilian municipalities of a minimum permeable area soil that should be left in each plot (plot territorial) of allotments that fits the sustainable concept. The research method was based on the observation of the behavior of some Brazilian cities [Antonio Carlos (SC), Biguaçu (SC), Criciúma (SC), Curitiba (PR), Ribeirão Preto (SP), São José (SC), and São José dos Campos (SP)] as well as other countries [Lisbon and Sintra (Portugal), Kitchener, Quebec, and Vancouver (Canada), and Liverpool (England)], especially in the areas of the infiltration minimum required to obtain a building permit. Research was also conducted to verify the respective regulations of maximum rates of land occupation and the minimum size defined for each lot, to avoid and/or minimize the occurrences of urban flooding. After a survey of normative data, six distinct simulations (minimum areas and average urban residential lots), were taken to verify the impact of the requirement of minimum area considered permeable. Finally, it is clear that for implementing a sustainable allotment, it is necessary to leave at least 25% of the area of permeable soil batch, resulting in a reduction of up to twice the volume of rainwater when compared with land in urban areas where the requirement does not apply. © 2014 American Society of Civil Engineers.


Lazzarotto C.,Federal University of Santa Catarina
Annals of hepatology | Year: 2013

Bacterial infection is a frequent complication in patients with decompensated liver cirrhosis and is related to high mortality rates during follow-up of these individuals. We sought to evaluate the diagnostic value of C-reactive protein (CRP) and procalcitonin (PCT) in diagnosing infection and to investigate the relationship between these biomarkers and mortality after hospital admission. Prospective study that included cirrhotic patients admitted to the hospital due to complications of the disease. The diagnostic accuracy of CRP and PCT for the diagnosis of infection was evaluated by estimating the sensitivity and specificity and by measuring the area under the receiver operating characteristics curve (AUROC). A total of 64 patients and 81 hospitalizations were analyzed during the study. The mean age was 54.31 ± 11.87 years with male predominance (68.8%). Significantly higher median CRP and PCT levels were observed among infected patients (P < 0.001). The AUROC of CRP and PCT for the diagnosis of infection were 0.835 ± 0.052 and 0.860 ± 0.047, respectively (P = 0.273). CRP levels > 29.5 exhibited sensitivity of 82% and specificity of 81% for the diagnosis of bacterial infection. Similarly, PCT levels > 1.10 showed sensitivity of 67% and specificity of 90%. Significantly higher levels of CRP (P = 0.026) and PCT (P = 0.001) were observed among those who died within three months after admission. CRP and PCT were reliable markers of bacterial infection in subjects admitted due to complications of liver cirrhosis and higher levels of these tests are related to short-term mortality in those patients.


Silva D.A.S.,Federal University of Santa Catarina
Perceptual and Motor Skills | Year: 2015

This study investigated the relationship between sufficient amounts of physical activity among Brazilian adolescents and the economic and social indicators of the cities where they live. Data from a large national survey including 109,104 boys and girls ages 13 to 15 yr. (47.8% boys, 52.2% girls) were analyzed. The economic and social indicators were the Human Development Index (HDI), which is a comparative measure to rank cities according to their degree of human development, the Gini index (income inequality), population density, and maternal education. Stepwise regression was used to identify associations between physical activity and economic and social indicators of the cities. The physical activity of Brazilian adolescents was associated with the social and economic conditions of the cities where they live. The amount of physical activity of girls was greater in the cities with fewer income inequalities. For boys, physical activity was greater in the cities with a higher HDI and fewer income inequalities. © Perceptual & Motor Skills 2015.


Holsbach Costa M.,Federal University of Santa Catarina
Computers in Biology and Medicine | Year: 2014

This work presents a complementary broadband noise reduction scheme for hearing aid applications. It is designed to attenuate uncorrelated and small-correlation-length acoustic noise with controlled speech distortion. Noisy speech signals are pre-processed by the proposed strategy before being subjected to an existing narrowband noise reduction system. The clean speech signal is estimated by a convex combination of the unprocessed speech signal and the output of a linear predictor. The convex combination coefficient is adjusted to provide noise suppression while avoiding significant unvoiced utterance distortions. The proposed method is optimized to minimize speech mean-square prediction-error. A low-cost adaptive implementation is proposed and compared to the conventional adaptive linear predictor showing an improved performance, as predicted by theory. Four different objective quality measures and subjective assessment performed by normal hearing volunteers indicate that the combined use of the proposed technique with a narrowband noise reduction system consistently improves speech quality for a range of signal to noise ratios. Low-cost digital hearing aids that make use of the conventional adaptive predictor for broadband noise reduction can be easily modified to incorporate the new proposal with a minimum amount of extra computational resources. © 2013 Elsevier Ltd.


Franca F.S.,Federal University of Santa Catarina
In vivo (Athens, Greece) | Year: 2014

The present study investigated the relationship between intestinal bifidobacteria and intake of commercial dietary oils of different fatty acids compositions on the development of aberrant crypt foci (ACF). Wistar rats were grouped according to diet and treatment with dimethylhydrazine (DMH): standard diet (CN), canola oil (CAN), olive oil (OLI), corn oil (COR), standard diet and DMH (CNDMH), canola oil and DMH (CANDMH), olive oil and DMH (OLIDMH) and corn oil and DMH (CORDMH). Diets and DMH did not alter the amount of bifidobacteria, fecal pH and serum total cholesterol level. DMH-treated groups had lower serum triglyceride levels compared to respective controls without DMH. Olive and corn oil diets resulted in higher hepatic cholesterol levels than standard diet under treatment with DMH. The numbers of ACF/field and cell proliferation were lower under treatment with CANDMH and OLIDMH, suggesting a protective effect of these oils on colorectal carcinogenesis.


Nazareno A.G.,Federal University of Santa Catarina | Jump A.S.,University of Stirling
Molecular Ecology | Year: 2012

Predicted parallel impacts of habitat fragmentation on genes and species lie at the core of conservation biology, yet tests of this rule are rare. In a recent article in Ecology Letters, Struebig (2011) report that declining genetic diversity accompanies declining species diversity in tropical forest fragments. However, this study estimates diversity in many populations through extrapolation from very small sample sizes. Using the data of this recent work, we show that results estimated from the smallest sample sizes drive the species-genetic diversity correlation (SGDC), owing to a false-positive association between habitat fragmentation and loss of genetic diversity. Small sample sizes are a persistent problem in habitat fragmentation studies, the results of which often do not fit simple theoretical models. It is essential, therefore, that data assessing the proposed SGDC are sufficient in order that conclusions be robust. © 2012 Blackwell Publishing Ltd.


Paduani C.,Federal University of Santa Catarina | Jena P.,Virginia Commonwealth University
Journal of Nanoparticle Research | Year: 2012

New types of magnetic hyperhalogen compounds are theoretically characterized by density functional theory and hybrid functional for exchangecorrelation potentials. A systematic study of the structure and geometries of neutral and anionic MgF n;Mg(BF 4) n = 1 → 3), and GdF n; Gd(BF 4) n (n= 1 → 4) clusters, performed at the B3LYP/sdd level for Gd and B3LYP/6-311++G(3df) level for F, B and Mg using the Gaussian-03 suite of programs, show that MgF 3 and GdF 4 with electron affinities of 6.18 and 6.85 eV, respectively, behave as superhalogens while Mg(BF 4) 3 and Gd(BF 4) 4 with electron affinities of 9.24 and 9.70 eV, respectively, behave as hyperhalogens. In addition, the magnetic moment on the Gd atom remains close to its atomic value irrespective of whether it is attached to F or BF 4 moieties. © Springer Science+Business Media B.V. 2012.


Kremer L.P.,Federal University of Santa Catarina | da Rocha R.M.,Federal University of Parana
Biological Invasions | Year: 2016

Predation may often influence native species dynamics and so may be important for the control of introduced species as well. Here, we examine how predation can regulate fouling communities on artificial substrates in the coast of Brazil. Specifically, we tested whether predators limit colonization and establishment of introduced species. A predation experiment using plastic plates as experimental replicates (predator excluded and not excluded) was carried out in Ceará, Bahia, São Paulo and Santa Catarina, between 3°S and 27°S. Ninety-eight species colonized the plates, 14 of which were introduced. While species richness was similar among the treatments (except in Santa Catarina), community structure varied by treatment and introduced species were less abundant in the predation treatment at all sites. Also, predation was selective and controlled introduced, poorly defended, species, specifically ascidians. Thus, biotic resistance driven by predation was not ubiquitous but apparently targets one group of major economic and environmental impact. As a consequence, introduced barnacles were released from competition with dominant ascidians and thus the ecosystem service (biotic resistance) performed by fish alone was unable to completely avoid or control the introduction of non-native species. Control measures must rely on various approaches, but if we want fish to contribute in this control, it is very important to conserve the local native assembly of predators in order to reap their benefits in this ecosystem service. © 2016 Springer International Publishing Switzerland


Kneur J.-L.,CNRS Charles Coulomb Laboratory | Pinto M.B.,Federal University of Santa Catarina | Ramos R.O.,State University of Rio de Janeiro
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2013

The phase diagram and thermodynamic properties of the (2+1)-dimensional Gross-Neveu model are studied in the presence of a constant magnetic field. The optimized perturbation theory (OPT) is used to obtain results going beyond the large-N approximation. The free energy and the complete phase diagram of the model, in terms of temperature, chemical potential, and magnetic field are obtained and studied in details. We find that some of the main qualitative changes induced by the OPT finite N corrections concern the region of intermediate to high chemical potentials where this approximation adds a term proportional to λâŸ̈ψ +ψ⟩2/N to the free energy. Then, depending on the sign of λ (relative to the critical coupling) and magnitude of the magnetic field, we observe a weakening (when λ<0) or enhancement (when λ>0) of the chiral broken region in the magnetized fermionic system. By comparing the results from the OPT and the large-N approximation, we conclude that finite N effects favor the phenomenon of inverse magnetic catalysis when the coupling constant is negative. We show that with the OPT the value of the coexistence chemical potential at vanishing temperature tends to decrease for large values of the magnetic field. This is opposite to what is seen in the large-N approximation, where for large magnetic fields the coexistence chemical potential starts again to increase. Likewise, at finite temperature, the value of the chemical potential at the tricritical point also decreases with the magnetic field in the OPT case. Consequently, the shape of the phase diagrams predicted by the OPT and by the large-N approximation look very different in the presence of high magnetic fields. Finally, for small values of magnetic field and temperature, we identify the presence of possible intermediate nonchiral phase transitions when varying the chemical potential. We show that these phenomena are not an artifact of the large-N approximation and that they also occur within the OPT framework. These intermediate transitions are interpreted to be a consequence of the de Haas-van Alphen oscillations. We also explain why this type of phenomenon can happen in general for negative couplings but not for positive couplings. © 2013 American Physical Society.


Objective: To analyze dissertations and theses produced by graduate programs in nutrition in Brazil from 2003 to 2012. We sought to identify: a) The number of studies produced per year b) the scientific approach (quantitative, qualitative, or mixed), and c) the area of knowledge in the scientific field of nutrition. Methods: This is a descriptive study. We investigated seven graduate programs linked to the area of nutrition of the Coordination for the Improvement of Higher Education Personnel, which had the web pages listing the studies. The analysis procedures included reading the titles, identifying the advisor's lines of research, reading the summaries, and reading the methods section. Results: In the study period 758 dissertations and 204 theses were defended, signifying an increase of 229.0% for the all programs. The hegemony of the quantitative approach shows the influence of the philosophical trends linked to positivism and the biological sciences, attracting interest from 92.5% of researchers. The qualitative and mixed approaches contributed only to 7.3% of the studies, expressing the influence of the social sciences and humanities and of the philosophical trends' dialectics and phenomenology about a small group of researchers. Conclusion: The distribution of dissertations and theses in the six areas of knowledge reaffirms the complexity, breadth, epistemological, and methodological heterogeneity; and the configuration of the field of knowledge production in food and nutrition, requiring the construction of collective political projects, seeking the interdisciplinarity of the different areas that structure the field.


Badin A.A.,Federal University of Parana | Barbi I.,Federal University of Santa Catarina
IEEE Transactions on Power Electronics | Year: 2011

This paper proposes an isolated three-phase rectifier power-factor correction using two single-phase buck preregulators in continuous conduction mode. The use of the Scott transformer renders a simple and robust rectifier to operate with unity power factor. With only two active switches, the rectifier is able to generate symmetrical currents in the line and a regulated voltage output without any necessary synchronous switches. The proposed control technique with sinusoidal pulse width modulation uses a feedforward of the output inductor current and only one voltage control regulates the output. Complete simulation results under closed-loop operation are given and a 12-kW prototype has been implemented in the laboratory, which demonstrated to operate successfully with excellent performance, and thus can feasibly be implemented in higher power applications. © 2010 IEEE.


D'Orsi E.,Federal University of Santa Catarina | Xavier A.J.,University of South Santa Catarina | Ramos L.R.,University of Sao Paulo
Revista de Saude Publica | Year: 2011

OBJECTIVE: To identify risk factors for functional capacity loss in elderly people. METHODS: Epidoso (Epidemiology of the Elderly) cohort study with elderly people living in São Paulo (Southeastern Brazil). A total of 326 participants in the first interview (1991-1992) who were independent or had mild dependence (one or two activities of daily living) were selected. Those who presented functional loss in the second (1994-1995) or third interviews (1998-1999) were compared to those who did not present it. The incidence of functional loss was calculated according to sociodemographic variables, life habits, cognitive status, morbidity, hospitalization, self-rated health, tooth loss, social support and leisure activities. Crude and adjusted relative risks with 95% confidence intervals were estimated through bivariate and multiple analyses with Poisson regression. The criterion for the inclusion of the variables in the model was p < 0.20 and for exclusion, p > 0.10. RESULTS: The incidence of functional loss was 17.8% (13.6; 21.9). The risk factors in the final model were: age group 70-74 years RR=1.9 (0.9;3.9); age group 75-79 years RR=2.8 (I.4;5.5); age group 80 years or older RR=5.4 (3.0;9.6); score in the mini-mental state examination <24 RR=1.8 (1.1;2.9); asthma RR=2.3 (1.3;3.9); hypertension RR= 1.7 (1.1;2.6); and diabetes RR=1.7 (0.9;3.0). The protective factors were: paid work RR=0.3 (0.1; 1.0); monthly relationship with friends RR=0.5 (0.3;0.8); watching TV RR=0.5 (0.3;0.9); and handcrafting RR=0.7 (0.4; 1.0). CONCLUSIONS: The prevention of functional loss should include adequate control of chronic diseases, like hypertension, asthma and diabetes, as well as cognitive stimulation. Work, leisure and relationships with friends should be valued due to their protective effect.


Castro L.B.,Federal University of Santa Catarina | Castro L.B.,Federal University of Maranhao | De Castro A.S.,Sao Paulo State University
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2014

It is shown that the Hamiltonian version of the Duffin-Kemmer-Petiau theory with electromagnetic coupling brings about a source term at the current. It is also shown that such a source term disappears from the scenario if one uses the correct physical form for the Duffin-Kemmer-Petiau field, regardless of the choice for representing the Duffin-Kemmer-Petiau matrices. This result is used to fix the ambiguity in the electromagnetic coupling in the Duffin-Kemmer-Petiau theory. Moreover, some widespread misconceptions about the Hermiticity in the Duffin-Kemmer-Petiau theory are discussed. © 2014 American Physical Society.


Carvalho A.O.,University of Campinas | Bruzi G.,Federal University of Santa Catarina | Giannini M.,University of Campinas | Magne P.,University of Southern California
Journal of Prosthetic Dentistry | Year: 2014

Statement of problem Various computer-aided design and computer-aided manufacturing (CAD/CAM) materials are available to fabricate complete crowns. The type of material may have an effect on the longevity of these restorations. Purpose To evaluate the fatigue resistance, load-to-failure, failure mode, and antagonistic wear of complete molar computer-aided design and computer-aided manufacturing (CAD/CAM) crowns made of resin nanoceramic (RNC), feldspathic glass ceramic (FEL), or lithium disilicate (LD) placed with a simplified cementation process. Material and methods Forty-five molars received a standardized complete crown preparation and were restored with CAD/CAM crowns (1.5-mm thickness, n=15) made of RNC, FEL, and LD. After cementation, the restorations were submitted to cyclic isometric loading: 200 (×5000), 400, 600, 800, 1000, 1200, and 1400 N at a maximum of 30000 cycles each. Surviving specimens were axially loaded until failure or to a maximum load of 4500 N. The specimens were analyzed as to failure mode: catastrophic, possibly repairable, and repairable. The groups were compared by using the life table survival analysis and the t test (α=.05). Results All the specimens survived the fatigue process until the 800-N step. The survival rate of RNC was 80%, LD 93.3%, and FEL 6.6%. The survival of RNC and LD crowns did not differ from each other but exceeded that of FEL. Postfatigue load-to-failure test was 2500 N (FEL), 3122 N (RNC), and 3237 N (LD). No catastrophic failure occurred in the fatigue test, whereas all of the specimens in the load-to-failure test exhibited catastrophic fractures. Crowns made of RNC seemed to generate the least amount of antagonistic wear. Conclusions Posterior crowns made of RNC and LD were not statistically different, and both had significantly higher fatigue resistance than FEL. All materials survived beyond the normal range of masticatory forces, and all failures were possibly re-restorable except those in the load-to-failure test. RNC crowns seemed to cause less wear of the antagonist.


Peres M.A.,Federal University of Santa Catarina
American journal of public health | Year: 2011

We assessed whether 3 models of life course socioeconomic status (critical period, accumulation of risk, and social mobility) predicted unsound teeth in adulthood among a Brazilian cohort. Life course data were collected on the 5914 live-born infants in the 1982 Pelotas Birth Cohort study. Participants' oral health was assessed at 15 (n = 888) and 24 (n = 720) years of age. We assessed family income trajectories and number of episodes of poverty in the life course through Poisson regressions, yielding unadjusted and adjusted prevalence ratios for number of unsound teeth at age 24 years. The adjusted prevalence ratio for participants born into poverty was 30% higher than for those who were not. Participants who were always poor had the highest prevalence of unsound teeth; those who were downwardly or upwardly mobile also had more unsound teeth than did other participants, after adjustment for confounders. More episodes of poverty were associated with greater prevalence of unsound teeth in adulthood. Poverty at birth and during the life course was correlated with the number of unsound teeth at 24 years of age.


Gandhi R.A.,Diabetes Research Unit | Marques J.L.B.,Diabetes Research Unit | Marques J.L.B.,Federal University of Santa Catarina | Selvarajah D.,Diabetes Research Unit | And 2 more authors.
Diabetes Care | Year: 2010

OBJECTIVE- Although a clear link between diabetic peripheral neuropathy (DPN) and autonomic neuropathy is recognized, the relationship of autonomic neuropathy with subtypes of DPN is less clear. This study aimed to investigate the relationship of autonomic neuropathy with painless and painful DPN. RESEARCH DESIGN AND METHODS- Eighty subjects (20 healthy volunteers, 20 with no DPN, 20 with painful DPN, 20 with painless DPN) underwent detailed neurophysiological investigations (including conventional autonomic function tests [AFTs]) and spectral analysis of short-term heart rate variability (HRV), which assesses sympathovagal modulation of the heart rate. Various frequency-domain (including low frequency [LF], high frequency [HF], and total power [TP]) and time-domain (standard deviation of all normal-to-normal R-R intervals [SDNN] and root mean square of successive differences [RMSSD]) parameters were assessed. RESULTS- HRV analysis revealed significant differences across the groups in LF, HF, TP, SDNN, and RMSSD (ANOVA P < 0.001). Subgroup analysis showed that compared with painless DPN, painful DPN had significantly lower HF (3.59 ± 1.08 [means ± SD] vs. 2.67 ± 1.56), TP (5.73 ± 1.28 vs. 4.79 ± 1.51), and SDNN (2.91 ± 0.65 vs. 1.62 ± 3.5), P < 0.05. No significant differences were seen between painless DPN and painful DPN using an AFT. CONCLUSIONS- This study shows that painful DPN is associated with significantly greater autonomic dysfunction than painless DPN. These changes are only detected using spectral analysis of HRV (a simple test based on a 5-min electrocardiogram recording), suggesting that it is a more sensitive tool to detect autonomic dysfunction, which is still under-detected in people with diabetes. The greater autonomic dysfunction seen in painful DPN may reflect more predominant small fiber involvement and adds to the growing evidence of its role in the pathophysiology of painful DPN. © 2010 by the American Diabetes Association.


Uarrota V.G.,Federal University of Santa Catarina
Journal of Agronomy | Year: 2010

This study was conducted in the experimental college of agriculture and forestry, in Maputo-Mozambique, in order to evaluate the response of cowpea (Vigna unguiculata L. Walp.) to irrigation and phosphorus and test the hypothesis that high levels of phosphorus improves the tolerance of plants to water stress. We used a variety IT 18 of cowpea, short cycle and ended. The experiment was subdivided into building plots complete block design with five repetitions, the irrigation factor was fixed at the main plot with two levels (with irrigation and without irrigation) and phosphorus factor in sub-plots with 3 levels (0, 20 and 40 kg ha-1 of phosphorus). The fertilization strongly influenced the yield and the number of pods per plant in both irrigation conditions. The effect of fertilizing phosphorus was higher under irrigation. The interaction was significant only for grain yield and number of pods, which means that the effect of phosphorus in these two variables has not been the same for the two levels of irrigation, high levels of phosphate fertilizer (P2O5) have improved the tolerance of cowpea when not irrigated. © 2010 Asian Network for Scientific Information.


Rona L.D.,Instituto Oswaldo Cruz | Carvalho-Pinto C.J.,Federal University of Santa Catarina | Peixoto A.A.,Instituto Oswaldo Cruz
Malaria Journal | Year: 2010

Background. Anopheles cruzii (Diptera: Culicidae) has long been known as a vector of human and simian malaria parasites in southern and south-eastern Brazil. Previous studies have provided evidence that An. cruzii is a species complex, but the status of the different populations and the number of sibling species remains unclear. A recent analysis of the genetic differentiation of the timeless gene among An. cruzii populations from south and south-east Brazil has suggested that the population from Itatiaia, Rio de Janeiro State (south-east Brazil), is in a process of incipient speciation. Methods. A ∼180 bp fragment of cpr, a gene encoding the NADPH-cytochrome P450 reductase, an enzyme involved in metabolic insecticide resistance and odorant clearance in insects, was used in this study as a molecular marker to analyse the divergence between five An. cruzii populations from south and south-east Brazil. Results. Analysis of the genetic differentiation in the cpr gene revealed very high F STvalues and fixed differences between Itatiaia and the other four populations studied (Florianápolis, Cananéia, Juquitiba and Santa Teresa). In addition, the data also provided preliminary evidence that seems to indicate the occurrence of two sympatric sibling species in Itatiaia. Conclusions. Population genetics analysis of An. cruzii samples from different localities using a fragment of the cpr gene suggests that the Itatiaia sample represents at least one new sibling species in this complex. © 2010 Rona et al; licensee BioMed Central Ltd.


Costa J.A.F.,Federal University of Santa Catarina
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2010

Self-organizing maps (SOM) had been used for input data quantization and visual display of data, an important property that does not exist in most of clustering algorithms. Effective data clustering using SOM involves two or three steps procedure. After proper network training, units can be clustered generating regions of neurons which are related to data clusters. The basic assumption relies on the data density approximation by the neurons through unsupervised learning. This paper presents a gradient-based SOM visualization method and compares it with U-matrix. It also discusses steps toward clustering using SOM and morphological operators. Results using benchmark datasets show that the new method is more robust to choice of parameters in the filtering phase than the conventional method. The paper also proposes an enhancing method to map visualization taking advantage of the neurons activity, which improve cluster detection especially in small maps. © 2010 Springer-Verlag Berlin Heidelberg.


Winck D.R.,Federal University of Santa Catarina
Revista brasileira de enfermagem | Year: 2010

The objective of this literature review is to identify how aspects related to legal responsibilities of the obstetrics nurse and the obstetrics nursing assistant have been approached in Brazilian publications. After researching the following databases for the period of 1980 to 2009; BDENF, CINAHL, LILACS, and SciELO, seven articles which dealt with judicial aspects were selected for this study. It was clear that none of these focused upon legal responsibilities for obstetrical nurses. Error prevention was highlighted among the majority of these publications, as well as civil and ethical responsibilities. However, the majority point out administrative sanctions and penal responsibilities. These aspects need to be researched in greater depth and reported upon, for they may contribute to more qualified formal education for nurses concerning the legal implications of their practice.


Minuzzi R.B.,Federal University of Santa Catarina
Revista Brasileira de Engenharia Agricola e Ambiental | Year: 2010

The objective of this work was to analyse the monthly variability of maximum temperature, minimum temperature, average temperature and rainfall in Santa Catarina, in three different periods from 1955 to 2008, in order to: 1) identify points with climatic change behavior, and 2) determine the climatic trends for these periods. To identify the points of climatic changes of time series the Standard Normal Homogeneity Test (SNHT) was used. The Regression Analysis and Mann-Kendall tests were used to assess the meteorological variables trends in different periods divided into points of descontinnity. Changes were identified in the behavior of the maximum temperature (minimum temperature) during 1995 to 1997 (from 1988 to 1991) showing a tendency to decrease (increase) since the mid 1950s. Considering the average temperature and the rainfall there is no defined period of change in temporal behavior, but a slight trend of increase.


Noskoski O.A.,Southern Federal Institute of Education and Technology | Bermudez J.C.M.,Federal University of Santa Catarina | De Almeida S.J.M.,Catholic University of Pelotas
IEEE Transactions on Signal Processing | Year: 2013

Identification of systems with sparse impulse response encounters large applicability. Numerous techniques have been proposed to identify such systems efficiently. One strategy that leads to specially good results is to detect the active (nonzero) response samples and update only the corresponding adaptive coefficients. Wavelet-based approaches have been shown to be specially effective to this end. This paper proposes a new region-based wavelet-packet (RBWP) algorithm for efficient identification of systems with sparse impulse responses with arbitrary frequency spectra and with any delay of the effective response. The discrete wavelet packet transform (DWPT) is adaptively tailored to the energy distribution of the unknown system's response spectrum. The new algorithm leads to a reduced number of active weights and to a reduced computational complexity, when compared with competing wavelet-based algorithms. Monte Carlo simulation results show good performances regarding convergence speed and robustness to design parameter choice. © 1991-2012 IEEE.


Gonzalez Delgado R.M.,Institute Astrofisica Of Andalucia Csic | Cid Fernandes R.,Federal University of Santa Catarina
Monthly Notices of the Royal Astronomical Society | Year: 2010

High spectral resolution evolutionary synthesis models have become a routinely used ingredient in extragalactic work, and as such deserve thorough testing. Star clusters are ideal laboratories for such tests. This paper applies the spectral fitting methodology outlined in Paper I to a sample of clusters, mainly from the Magellanic Clouds and spanning a wide range in age and metallicity, fitting their integrated light spectra with a suite of modern evolutionary synthesis models for single stellar populations. The combinations of model plus spectral library employed in this investigation are Galaxev/STELIB, Vazdekis/MILES, SEDcommat/GRANADA and Galaxev/MILES+GRANADA, which provide a representative sample of models currently available for spectral fitting work. A series of empirical tests are performed with these models, comparing the quality of the spectral fits and the values of age, metallicity and extinction obtained with each of them. A comparison is also made between the properties derived from these spectral fits and literature data on these nearby, well studied clusters. These comparisons are done with the general goal of providing useful feedback for model makers, as well as guidance to the users of such models. We find the following. (i) All models are able to derive ages that are in good agreement both with each other and with literature data, although ages derived from spectral fits are on average slightly older than those based on the S-colour-magnitude diagram (S-CMD) method as calibrated by Girardi et al. (ii) There is less agreement between the models for the metallicity and extinction. In particular, Galaxev/STELIB models underestimate the metallicity by ∼0.6 dex, and the extinction is overestimated by 0.1 mag. (iii) New generations of models using the GRANADA and MILES libraries are superior to STELIB-based models both in terms of spectral fit quality and regarding the accuracy with which age and metallicity are retrieved. Accuracies of about 0.1 dex in age and 0.3 dex in metallicity can be achieved as long as the models are not extrapolated beyond their expected range of validity. © 2010 The Authors. Journal compilation © 2010 RAS.


Cid Fernandes R.,Federal University of Santa Catarina | Gonzalez Delgado R.M.,Institute Astrofisica Of Andalucia Csic
Monthly Notices of the Royal Astronomical Society | Year: 2010

High-resolution spectral models for simple stellar populations (SSP) developed in the past few years have become a standard ingredient in studies of stellar population of galaxies. As more such models become available, it becomes increasingly important to test them. In this and a companion paper, we test a suite of publicly available evolutionary synthesis models using integrated optical spectra in the blue-near-UV range of 27 well-studied star clusters from the work of Leonardi and Rose spanning a wide range of ages and metallicities. Most (23) of the clusters are from the Magellanic Clouds. This paper concentrates on the methodological aspects of spectral fitting. The data are fitted with SSP spectral models from Vazdekis and collaborators, based on the Medium-resolution INT Library of Empirical Spectra. Best-fitting and Bayesian estimates of age, metallicity and extinction are presented, and degeneracies between these parameters are mapped. We find that these models can match the observed spectra very well in most cases, with small formal uncertainties in t, Z and AV. In some cases, the spectral fits indicate that the models lack a blue old population, probably associated with the horizontal branch. This methodology, which is mostly based on the publicly available code starlight, is extended to other sets of models in Paper II, where a comparison with properties derived from spatially resolved data (colour-magnitude diagrams) is presented. The global aim of these two papers is to provide guidance to users of evolutionary synthesis models and empirical feedback to model makers. © 2010 The Authors. Journal compilation © 2010 RAS.


Moyano C.F.,Queensland University of Technology | Salgado R.S.,Federal University of Santa Catarina
Electric Power Systems Research | Year: 2010

This work proposes a parameterized formulation of the optimal power flow (OPF) problem, which is aimed at preventing the divergence of the OPF iterative process. A parameter, whose function is to adjust the power demand and/or operational limits in case of absence of feasible solutions, is added to the objective function of the original optimization problem. This modified problem is solved through the nonlinear version of the predictor-corrector interior point method. Besides indicating the potential reasons for non-convergence of the iterative process, the proposed methodology also provides the possible actions that could be taken to determine an operational solution. Numerical results obtained with test systems of different sizes illustrate the application of the proposed strategy. © 2010 Elsevier B.V. All rights reserved.


Neves M.A.,Federal University of Santa Catarina | Binder M.,Clark University | Halling R.,New York Botanical Garden | Hibbett D.,Clark University | Soytong K.,King Mongkuts University of Technology Thonburi
Fungal Diversity | Year: 2012

The phylogeny of Phylloporus (Boletaceae) has not been well studied, and the taxonomic relationships of this genus have varied considerably among authors. The following study presents phylogenetic relationships of Phylloporus based on two nuclear ribosomal DNA regions, ITS and LSU. The ITS dataset includes 39 collections and the LSU dataset contains 50 collections of Phylloporus. A combined analysis of both genes did not resolve the deeper nodes in the phylogeny, but the results suggest that Phylloporus is monophyletic and a sister group of the Xerocomus subtomentosus group. The lamellate hymenophore configuration is a synapomorphy that distinguishes Phylloporus from the other genera in the family. The placement of a lamellate genus within Boletaceae suggests that hymenophore evolution is not well understood in the family. This is the first phylogeny of Phylloporus and includes 20 species from different geographic regions. Six taxa of Phylloporus from the Old World are here presented. Phylloporus cyanescens is a new combination for an Australasian taxon formerly named as a variety of P. bellus (Massee) Corner. Phylloporus pumilus is described from Indonesia, and 4 species are described from Thailand: P. castanopsidis, P. dimorphus, P. infuscatus, and P. rubiginosus. © The Mushroom Research Foundation 2012.


Sichieri R.,Pontifical Catholic University of Rio de Janeiro | Dos Santos Barbosa F.,Pontifical Catholic University of Rio de Janeiro | Moura E.C.,Federal University of Santa Catarina
British Journal of Nutrition | Year: 2010

To ascertain the association of BMI and obesity with short stature, a cross-sectional telephone survey was conducted in 2006, using a multilevel approach, adjusting for individual-and city-level measures of socio-economic status. The study probabilistic sample consisted of 54369 adults (>18 years) living in households with access to telephone lines in each urban area of the twenty-six Brazilian state capitals and federal district. Odds of being currently obese and obese at age 20 years were compared between short stature individuals (5th percentile) and those with normal stature. After controlling for individual-and city-level sociodemographic characteristics and behaviours, high BMI was strongly associated with short stature individuals (P=0001). Among short stature women the adjusted OR of being obese was 30 (95% CI 22, 42) compared with those with stature greater than the 5th percentile. Among men this adjusted OR was 20 (95% CI 15, 26). When comparisons were made for BMI at age 20 years the OR were even larger (6 for men and 8 for women). Despite the growing body of evidence that environmental factors such as poor food choices and physical inactivity are the main determinants of the worldwide obesity epidemic, the greater difference in BMI and prevalence of obesity in the Brazilian capitals was explained mainly by individual factors. We found a strong association between obesity and short stature after adjustment for diet, physical activity, and many environmental factors. Intra-and inter-generational consequences of undernutrition are an alternative explanation for the regional disparities in obesity in Brazil. © 2010 The Authors.


De Vasconcelos F.A.G.,Federal University of Santa Catarina
Revista de Nutricao | Year: 2016

This article aims to perform a narrative review of the book "The mansions and the shanties" written by the Brazilian sociologist Gilberto Freyre, published for the first time in 1936. The study analyzed Gilberto Freyre's contribution to the process of interpreting the formation and modification of the eating habits and patterns of the Brazilian society. The analysis is limited to a review, from a dietician's perspective, of text clippings where Freyre seeks to reconstruct and interpret the process of formation and modification of eating habits and patterns in the context of a patriarchal society. The text will try to answer the questions: what, how much, how, when, where, and with whom were the dwellers of mansions and shanties eating? Comparison of the eating habits of the rural patriarchal society with those of the emerging urban patriarchal society has shown Freyre's clear trend of aversion to the "Europeanization" of eating habits and his affection for traditional culinary values. The new eating habits of mansions and plantation houses were portrayed with disdain, denoting an author who remained stuck to the culinary traditions of a rural patriarchal society, to taste memories, especially of the sweets, cakes, and desserts created, adapted, and savored in Pernambuco state sugar mills.


de Vasconcelos F.A.G.,Federal University of Santa Catarina | Calado C.L.A.,Federal University of Rio Grande do Norte
Revista de Nutricao | Year: 2011

Objective: This study made a historical analysis of the 70 years of the profession of dietician in Brazil, attempted to analyze the increase in the number of undergraduate nutrition courses and dieticians in the country and analyzed the identity of the Brazilian dietician in the current context. Methods: The empirical basis was based on the number of professionals and courses offered by the Federal Council of Dieticians and on the Federal Council of Dieticians research Insertion of Professional Dieticians in Brazil, done in 2005. Results: There were 391 courses of nutrition in Brazil (324 private and 67 public), enrolling 49,185 students yearly in August 2009. In June 2009, there were 60,554 registered dieticians in the country, resulting in a ratio of one dietician per 3,162 inhabitants. According to the 2005 Federal Council of Dieticians' research, Brazilian dieticians have the following profile: 96.5% are females, 79.4% aged 20 to 40 years, 53.6% are single, 79.1% are Caucasian, 41.7% were working in clinical nutrition, 32.2% in food services, 9.4% in academia, 8.8% in public health, 4.1% in sports nutrition and 3.7% in the food industry. Conclusion: The analysis shows a steep increase in number of courses and professionals and diversification of the dietician's areas of expertise. Additionally, within the seven major areas of expertise recognized by the Federal Council of Dieticians, there is a major process of division of their work objects. It is likely that changes in the labor market and work areas will take place in the near future because of the greater number of professionals in the market and their geographical redistribution.


Forgerini F.L.,Federal University of Amazonas | Figueiredo W.,Federal University of Santa Catarina
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics | Year: 2010

We present some results of Monte Carlo simulations for the deposition of particles of different sizes on a two-dimensional substrate. The particles are linear, height one, and can be deposited randomly only in the two x and y directions of the substrate and occupy an integer number of cells of the lattice. We show there are three different regimes for the temporal evolution of the interface width. At the initial times we observe an uncorrelated growth, with an exponent β1 characteristic of the random deposition model. At intermediate times, the interface width presents an unusual behavior, described by a growing exponent β2, which depends on the size of the particles added to the substrate. If the linear size of the particle is two we have β2 < β1, otherwise we have β2 > β1, for all other particle sizes. After the growth reaches the saturation regime where the interface width becomes constant and is described by the roughness exponent α, which is nearly independent of the size of the particle. Similar results are found in the surface growth due to the electrophoretic deposition of polymer chains. Contrary to one-dimensional results the growth exponents are nonuniversal. © 2010 The American Physical Society.


Fadel Miguel L.F.,Federal University of Santa Catarina | Holdorf Lopez R.,Federal University of Santa Catarina | Fadel Miguel L.F.,Federal University of Rio Grande do Sul
Journal of Sound and Vibration | Year: 2013

This paper presents a hybrid stochastic/deterministic optimisation algorithm to solve the target optimisation problem of vibration-based damage detection. The use of a numerical solution of the representation formula to locate the region of the global solution, i.e., to provide a starting point for the local optimiser, which is chosen to be the Nelder-Mead algorithm (NMA), is proposed. A series of numerical examples with different damage scenarios and noise levels was performed under impact and ambient vibrations. Thereafter, an experimental study of three cantilever beams with several different damage scenarios was conducted. To test the accuracy and efficiency of the optimisation algorithm, its results were compared to previous procedures available in the literature, which employed different solutions such as the genetic algorithm (GA), the harmony search algorithm (HS) and the particle swarm optimisation (PSO) algorithm. The performance of the proposed optimisation scheme was more accurate and required a lower computational cost than the GA, HS and PSO algorithms, emphasising the capacity of the proposed methodology for its use in damage diagnosis and assessment. In addition, the methodology was able to handle incomplete measurements and truncated mode shapes, which is of paramount importance for dealing with operational conditions in long-term structural health monitoring (SHM) applications. © 2013 Elsevier B.V. All rights reserved.


Hausmann R.,Regional University of Blumenau | Barbi I.,Federal University of Santa Catarina
IEEE Transactions on Power Electronics | Year: 2011

A new three-phase multilevel dc-ac converter with four-state switching cell is presented in this paper. Initially, the power stage diagram is presented and discussed. Its main characteristics are described and the more relevant waveforms, generated by simulation, are shown. After that, the converter operation is presented and all topological states are shown. The vectorial interpretation of the load voltage is shown to all available vectors of load voltage in the new topology. Next, the operation of the converter with sinusoidal pulse width modulation is discussed and some relevant figures are presented. In the sequence, the four-state switching cell is presented and the presence of the three-phase coupled inductor to provide significant reduction in harmonic distortion is discussed. A prototype with 15-kW output power was build with switching frequency equal to 9 kHz and dc link voltage was 300 V. Finally, the related results obtained from the implemented prototype are presented and briefly discussed. © 2011 IEEE.


Khan A.A.,Aligarh Muslim University | Baig U.,Aligarh Muslim University | Khalid M.,Federal University of Santa Catarina
Journal of Industrial and Engineering Chemistry | Year: 2013

Electrically conductive polyaniline-titanium(IV)molybdophosphate (PANI-TMP) cation exchange nanocomposite was studied as sensing material for aliphatic alcohols (methanol, ethanol and 1-propanol) at room temperature. The nanocomposite was synthesized by sol-gel mixing of polyaniline (PANI) into inorganic precipitate of titanium(IV)molybdophosphate (TMP) and characterized by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction analysis (XRD), thermogravimetric analysis (TGA) and ultraviolet-visible spectroscopy (UV-Vis). The composite showed good ion-exchange capacity, electrical conductivity and resistivity response towards alcohol vapours. It was observed that the sensor show good reversible response towards methanol vapours compared to ethanol and 1-propanol vapours. These studies suggest that the nanocomposite cation exchanger could be a good sensing material for methanol vapours at room temperature (25 °C). © 2012 The Korean Society of Industrial and Engineering Chemistry.


Da Silva Coqueiro R.,State University of Southwest Bahia | Ferreti Borgatto A.,Federal University of Santa Catarina
Journal of Nutrition, Health and Aging | Year: 2010

Objective: To assess the association of nutritional status with sex, age, race/color, education, smoking, physical activity, hypertension, diabetes, and hospitalization in older adults residing in the city of Havana, Cuba. Methods: This was a cross-sectional, population-based household survey. A total of 1,905 persons (1,197 women and 708 men; ≥ 60 years) were examined between 1999 and 2000, selected by probabilistic sampling. Nutritional status was assessed by body mass index (BMI): BMI < 22,0 kg/m2 = underweight; BMI > 27,0 kg/m2 = overweight. Multinomial logistic regression analysis (crude and adjusted) was used. Results: The estimation of the prevalence of underweight was 33.0% and that of overweight was 29.6%. The adjusted regression model showed that the probability of underweight was higher in older age groups (OR = 1.63, 70-79 years; OR = 2.05, ≥ 80 years) and among smokers (OR = 1.83). There was negative association between underweight, and hypertension and diabetes. Hypertension (OR = 1.99) was positively associated with overweight. The lower likelihood of overweight was observed among men, smokers, and those aged 80 years and more. Conclusion: The elderly population of Havana presents a vulnerable nutritional status in view of the prevalence of underweight and overweight. Increasing age, smoking, gender, and hypertension are the factors positively associated with vulnerable nutritional status. © 2010 Serdi and Springer Verlag France.


Frenking G.,University of Marburg | Caramori G.F.,Federal University of Santa Catarina
Angewandte Chemie - International Edition | Year: 2015

Hydrogen bonds: An approach based on energy decomposition analysis is discussed in the analysis of the bonding energy in hydrogen-bonded anion-anion and cation-cation complexes (see picture). The electrostatic Coulombic energy between the two fragments in the complexes is calculated based on the electron density distribution and not based on point charges. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Neiva de Figueiredo J.,Saint Josephs University | Mayerle S.F.,Federal University of Santa Catarina
Renewable Energy | Year: 2014

Anaerobic bio-digestion/energy generation complexes using animal waste raw materials represent an important component of renewable energy initiatives and policies worldwide, and are significant contributors to broaden sustainability efforts. In such projects bio-power feasibility depends heavily on generation complex access to biomass which is of costly transportation. As a result, an important component of renewable energy planning is the optimization of a logistics system to guarantee low-cost access to animal waste. This access is a function of local characteristics including number and geographic location of organic waste sources, operating and maintenance costs of the generation facility, energy prices, and marginal contribution of biomass collected and delivered to the anaerobic bio-digestion unit. Because biomass exhibits high transportation costs per unit of energy ultimately generated, and because different types of biomass have different biogas-generating properties, design of the supply logistics system can be the determinant factor towards economic viability of energy generation from an anaerobic bio-digestion plant. Indeed, to address this problem it is helpful to consider the farms, the logistics system, the anaerobic bio-digestion plant, and the generation plant as subsystems in an integrated system. Additionally, the existence of an outlet for manure may allow farmers to significantly raise boundaries of one constraint they face, namely disposing of animal waste, therefore permitting increases in farm production capacity. This paper suggests and outlines a systematic methodology to address the design of such systems. © 2014 Elsevier Ltd.


Rodrigues R.R.,Federal University of Santa Catarina | McPhaden M.J.,National Oceanic and Atmospheric Administration
Geophysical Research Letters | Year: 2014

The Brazilian Northeast (NE) is strongly affected by El Niño-Southern Oscillation (ENSO). During La Niña events, the precipitation over the NE is generally above average. However, during the last La Niña event in 2011-2012, the NE went through its worst drought in the last 30 years. In this study, observations and numerical simulations are used to determine what made the 2011-2012 event different from other events. We find that eastern Pacific (canonical) La Niña events cause a cooling of the tropical North Atlantic and warming of the tropical South Atlantic that lead to a southward migration of the Intertropical Convergence Zone, which in turn brings rain to the NE. On the other hand, La Niña events with the cooling concentrated in the central Pacific cause the opposite meridional sea surface temperature (SST) gradient in the tropical Atlantic, leading to droughts over the NE. The 2011-2012 event was of the latter type. This study also shows that it is possible to predict the sign of the NE rainfall anomaly during ENSO events using a simple SST index. Key Points ENSO drives SST anomalies in the tropical Atlantic Central and eastern Pacific events cause opposite precipitation responses A simple inter-basin SST index can be used to predict Northeast precipitation ©2014. American Geophysical Union. All Rights Reserved.


Da Silva J.N.,Federal University of Rio Grande do Sul | Salcedo E.,Federal University of Santa Catarina | De Oliveira A.B.,Federal University of Ouro Preto | Barbosa M.C.,Federal University of Rio Grande do Sul
Journal of Chemical Physics | Year: 2010

Using molecular dynamic simulations, we study a system of particles interacting through a continuous core-softened potentials consisting of a hard core, a shoulder at closest distances, and an attractive well at further distance. We obtain the pressure-temperature phase diagram of this system for various depths of the tunable attractive well. Since this is a two length scale potential, density, diffusion, and structural anomalies are expected. We show that the effect of increasing the attractive interaction between the molecules is to shrink the region in pressure in which the density and the diffusion anomalies are present. If the attractive forces are too strong, particle will be predominantly in one of the two length scales and no density of diffusion anomaly is observed. The structural anomalous region is present for all the cases. © 2010 American Institute of Physics.


Horai R.,U.S. National Institutes of Health | Zarate-Blades C.R.,U.S. National Institutes of Health | Zarate-Blades C.R.,Federal University of Santa Catarina | Dillenburg-Pilla P.,U.S. National Institutes of Health | And 10 more authors.
Immunity | Year: 2015

Activated retina-specific T cells that have acquired the ability to break through the blood-retinal barrier are thought to be causally involved in autoimmune uveitis, a major cause of human blindness. It is unclear where these autoreactive T cells first become activated, given that their cognate antigens are sequestered within the immune-privileged eye. We demonstrate in a novel mouse model of spontaneous uveitis that activation of retina-specific T cells is dependent on gut commensal microbiota. Retina-specific T cell activation involved signaling through the autoreactive T cell receptor (TCR) in response to non-cognate antigen in the intestine and was independent of the endogenous retinal autoantigen. Our findings not only have implications for the etiology of human uveitis, but also raise the possibility that activation of autoreactive TCRs by commensal microbes might be a more common trigger of autoimmune diseases than is currently appreciated. It is unknown where and how T cells reactive to self antigens residing behind blood-tissue barriers first become activated. Caspi and colleagues show that retina-specific T cells receive an activation signal in the gut from a crossreactive antigen dependent on commensal microbiota and trigger autoimmunity in the eye. © 2015 Elsevier Inc.


Zonin V.J.,Federal University of Santa Catarina | Valle Antunes J.A.,University of the Rio dos Sinos Valley | Pinto Leis R.,University of the Rio dos Sinos Valley
Energy Policy | Year: 2014

Energy crises reverberate within societies and encourage worldwide change in this industry. In this context, Brazil has been consolidating the National Program for the Production and Use of Biodiesel (Programa Nacional de Produção e Uso do Biodiesel-PNPB). This article analyzes BSBIOS and PETROBRAS BIOFUELS, which is a company that is incorporated under the PNPB. After providing an overview, the manuscript focuses on the criteria used for the selection of the agricultural raw materials used in the biodiesel industry. A reference model that considered the economic, technological, and social dimensions was developed; these dimensions were analyzed in relation to the production matrices of the soybean, canola, sunflower, and castor plants. The company strategically opted to establish programs for promoting the production of only soybean and canola. In the short term, the company has accepted the evidence that the main source of raw materials is soybean production. This decision was made considering the multicriteria analysis that was developed, which involved a number of economic, technological, and social aspects. Consequently, this analysis used in the decision-making process exhibits both a macro (the national and international environment) and a micro perspective (the companies' reality). © 2014 Published by Elsevier Ltd.


Oliveira L.H.,Sao Paulo State University | Moura A.P.D.,Sao Paulo State University | Longo E.,Sao Paulo State University | Varela J.A.,Sao Paulo State University | Rosa I.L.V.,Federal University of Santa Catarina
Journal of Alloys and Compounds | Year: 2013

Rare earth complexes (RE) can be incorporated in silica matrixes, originating organic/inorganic hybrid materials with good thermal stability and high rare earth emission lines. In this work, the hybrid material was obtained by the polymeric precursor method and ultrasonic dispersed with spherical silica particles prepared by the Stöber Method. The Raman spectra indicated that the Eu3+ ions are involved in a polymeric structure formed as consequence of the chelation and polyesterification reactions of this ion with citric acid and ethylene glycol. After the ultrasonic stirring, 2-hydroxynicotinic ligand will also compose this polymeric rigid structure. The TGA/DTA analysis showed that this polymeric material was thermal decomposed at 300 °C. Moreover, this process allows the chelating process of the 2-hydroxynicotinic acid ligand to the Eu3+ ions. The 29Si NMR showed that the ultrasonic dispersion of the reactants was not able to promote the functionalization of the silica particles with the 2-hydroxynicotinic acid ligand. Moreover, heat treatment promotes the [Eu(HnicO2)3] complex particles incorporation into silica pores. At this temperature, the TGA curve showed that only the thermal degradation of ethylene glycol and citric acid used during the experimental procedure occurs. The silica and hybrid materials are composed by spherical and aggregated particles with particle size of approximately 450 nm, which can be influenced by the heat treatment. These materials also present an absorption band located at 337 nm. The photoluminescent study showed that when the hybrid samples were excited at 337 nm wavelength, the ligand absorbs the excitation light. Part of this energy is transferred to the Eu3+ ion, which main emission, 5D0→ 7F2, is observed in the emission spectrum at 612 nm. As the heating temperature increases to 300 C, the energy transfer is more favorable. The lifetime values showed that the Eu3+ emission is enhanced due to the energy transfer process in the powders. © 2013 Elsevier B.V. All rights reserved.


Kneur J.-L.,CNRS Charles Coulomb Laboratory | Pinto M.B.,Federal University of Santa Catarina
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2015

A recently developed variant of the so-called optimized perturbation theory (OPT), making it perturbatively consistent with renormalization group (RG) properties, RGOPT, was shown to drastically improve its convergence for zero temperature theories. Here the RGOPT adapted to finite temperature is illustrated with a detailed evaluation of the two-loop pressure for the thermal scalar λφ4 field theory. We show that already at the simple one-loop level this quantity is exactly scale-invariant by construction and turns out to qualitatively reproduce, with a rather simple procedure, results from more sophisticated resummation methods at two-loop order, such as the two-particle irreducible approach typically. This lowest order also reproduces the exact large-N results of the O(N) model. Although very close in spirit, our RGOPT method and corresponding results differ drastically from similar variational approaches, such as the screened perturbation theory or its QCD-version, the (resummed) hard thermal loop perturbation theory. The latter approaches exhibit a sensibly degrading scale dependence at higher orders, which we identify as a consequence of missing RG invariance. In contrast RGOPT gives a considerably reduced scale dependence at two-loop level, even for relatively large coupling values λ/24∼O(1), making results much more stable as compared with standard perturbation theory, with expected similar properties for thermal QCD. © 2015 American Physical Society.


Farias R.L.S.,Federal University of Sao Joao del Rei | Farias R.L.S.,Federal University of Santa Maria | Gomes K.P.,Federal University of Sao Joao del Rei | Krein G.,Sao Paulo State University | Pinto M.B.,Federal University of Santa Catarina
Physical Review C - Nuclear Physics | Year: 2014

Although asymptotic freedom is an essential feature of QCD, it is absent in effective chiral quark models like the Nambu-Jona-Lasinio and linear sigma models. In this work we advocate that asymptotic freedom plays a key role in the recently observed discrepancies between results of lattice QCD simulations and quark models regarding the behavior of the pseudocritical temperature Tpc for chiral-symmetry restoration in the presence of a magnetic field B. We show that the lattice predictions that Tpc decreases with B can be reproduced within the Nambu-Jona-Lasinio model if the coupling constant G of the model decreases with B and the temperature. Without aiming at numerical precision, we support our claim by considering a simple ansatz for G that mimics the asymptotic-freedom behavior of the QCD coupling constant 1/αs∼ln(eB/ΛQCD2) for large values of B. © 2014 American Physical Society.


Luiz O.J.,Macquarie University | Madin J.S.,Macquarie University | Ross Robertson D.,Smithsonian Tropical Research Institute | Rocha L.A.,Golden Gate | And 2 more authors.
Proceedings of the Royal Society B: Biological Sciences | Year: 2012

How do biogeographically different provinces arise in response to oceanic barriers to dispersal? Here, we analyse how traits related to the pelagic dispersal and adult biology of 985 tropical reef fish species correlate with their establishing populations on both sides of two Atlantic marine barriers: the Mid-Atlantic Barrier (MAB) and the Amazon-Orinoco Plume (AOP). Generalized linear mixed-effects models indicate that predictors for successful barrier crossing are the ability to raft with flotsam for the deep-water MAB, non-reef habitat usage for the freshwater and sediment-rich AOP, and large adult-size and large latitudinal-range for both barriers. Variation in larval-development mode, often thought to be broadly related to larval-dispersal potential, is not a significant predictor in either case. Many more species of greater taxonomic diversity cross the AOP than the MAB. Rafters readily cross both barriers but represent a much smaller proportion of AOP crossers than MAB crossers. Successful establishment after crossing both barriers may be facilitated by broad environmental tolerance associated with large body size and wide latitudinal-range. These results highlight the need to look beyond larval-dispersal potential and assess adult-biology traits when assessing determinants of successful movements across marine barriers. © 2011 The Royal Society.


Miguel L.F.F.,Federal University of Rio Grande do Sul | Fadel Miguel L.F.,Federal University of Santa Catarina
Expert Systems with Applications | Year: 2012

Mass optimization on shape and sizing with multiple natural frequency constraints are highly nonlinear dynamic optimization problems. Multiple natural frequency constraints normally cause difficult dynamic sensitivity analysis and, in addition, two different types of design variables, nodal coordinates and cross-sectional areas, often lead to divergence. Thus, the choice of the appropriated method to solve this kind of problem is of paramount importance. Within this context, in this paper two of the most recent metaheuristic algorithms developed in the last decade, Harmony Search (HS) and Firefly Algorithm (FA), are used, for the first time here, to solve truss shape and sizing optimization with multiple natural frequency constraints. Since these metaheuristic algorithms are not a gradient-based search, they avoid most of the pitfalls of any gradient-based search algorithms. The effectiveness of Harmony Search and Firefly Algorithm is demonstrated through four benchmark structural optimization problems for solving shape and sizing optimization of trusses with multiple frequency constraints. The results showed that both metaheuristic algorithms reached, in a relatively low computational time, better results than the literature in three of the four examples considered, and in the other example the structure is approximately equal to the best one found, emphasizing the excellent capacity of both methods. © 2012 Elsevier Ltd. All rights reserved.


Kneur J.-L.,Montpellier University | Pinto M.B.,Lawrence Berkeley National Laboratory | Pinto M.B.,Federal University of Santa Catarina | Ramos R.O.,State University of Rio de Janeiro | Ramos R.O.,University of Edinburgh
Physical Review C - Nuclear Physics | Year: 2010

The optimized perturbation theory (OPT) method is applied to the SU(2) version of the Nambu-Jona-Lasinio (NJL) model both at zero and at finite temperature and/or density. At the first nontrivial order, the OPT exhibits a class of 1/Nc corrections which produce nonperturbative results that go beyond the standard large-Nc or mean-field approximation. The consistency of the OPT method with the Goldstone theorem at this order is established, and appropriate OPT values of the basic NJL (vacuum) parameters are obtained by matching the pion mass and decay constant consistently. Deviations from standard large-Nc relations induced by OPT at this order are derived, for example, for the Gell-Mann-Oakes-Renner relation. Next, the results for the critical quantities and the phase diagram of the model, as well as a number of other thermodynamical quantities of interest, are obtained with OPT and then contrasted with the corresponding results at large Nc. © 2010 The American Physical Society.


Silva J.C.D.,NASA | Silva J.C.D.,Federal University of Santa Catarina | Saxena A.,NASA | Balaban E.,NASA | Goebel K.,NASA
Expert Systems with Applications | Year: 2012

Sensors are vital components for control and advanced health management techniques. However, sensors continue to be considered the weak link in many engineering applications since often they are less reliable than the system they are observing. This is in part due to the sensors' operating principles and their susceptibility to interference from the environment. Detecting and mitigating sensor failure modes are becoming increasingly important in more complex and safety-critical applications. This paper reports on different techniques for sensor fault detection, disambiguation, and mitigation. It presents an expert system that uses a combination of object-oriented modeling, rules, and semantic networks to deal with the most common sensor faults, such as bias, drift, scaling, and dropout, as well as system faults. The paper also describes a sensor correction module that is based on fault parameters extraction (for bias, drift, and scaling fault modes) as well as utilizing partial redundancy for dropout sensor fault modes). The knowledge-based system was derived from the results obtained in a previously deployed Neural Network (NN) application for fault detection and disambiguation. Results are illustrated on an electro-mechanical actuator application where the system faults are jam and spalling. In addition to the functions implemented in the previous work, system fault detection under sensor failure was also modeled. The paper includes a sensitivity analysis that compares the results previously obtained with the NN. It concludes with a discussion of similarities and differences between the two approaches and how the knowledge based system provides additional functionality compared to the NN implementation. © 2012 Elsevier Ltd. All rights reserved.


Panda P.K.,University of Coimbra | Providencia C.,University of Coimbra | Menezes D.P.,Federal University of Santa Catarina
Physical Review C - Nuclear Physics | Year: 2010

In the present article, we investigate stellar matter obtained within the quark-meson-coupling (QMC) model for fixed temperature and with the entropy of the order of 1 or 2 Boltzmann units per baryon for neutrino-free matter and matter with trapped neutrinos. A new prescription for the calculation of the baryon effective masses in terms of the free energy is used. Comparing the results of the present work with those obtained from the nonlinear Walecka model, smaller strangeness and neutrino fractions are predicted within QMC. As a consequence, QMC has a smaller window of metastability for conversion into a low-mass blackhole during cooling. © 2010 The American Physical Society.


Goncalves V.P.,Federal University of Pelotas | Kugeratski M.S.,Federal University of Santa Catarina | Navarra F.S.,University of Sao Paulo
Physical Review C - Nuclear Physics | Year: 2010

Heavy quark production has been very well studied over the last years both theoretically and experimentally. Theory has been used to study heavy quark production in ep collisions at HERA, in pp collisions at Tevatron and RHIC, in pA and dA collisions at RHIC, and in AA collisions at CERN-SPS and RHIC. However, to the best of our knowledge, heavy quark production in eA has received almost no attention. With the possible construction of a high energy electron-ion collider, updated estimates of heavy quark production are needed. We address the subject from the perspective of saturation physics and compute the heavy quark production cross section with the dipole model. We isolate shadowing and nonlinear effects, showing their impact on the charm structure function and on the transverse momentum spectrum. © 2010 The American Physical Society.


de Oliveira C.R.,Federal University of Santa Catarina
Physics Letters, Section A: General, Atomic and Solid State Physics | Year: 2010

It is argued that Dirichlet is the physical boundary condition at the origin for the one-dimensional hydrogen atom: The three-dimensional hydrogen atom is confined to a tube, and the limit as the diameter of the tube cross section goes to zero is taken. It is shown that the energy expectations are finite only in case of Dirichlet boundary condition. © 2010 Elsevier B.V. All rights reserved.


Costa E Silva I.P.,Federal University of Santa Catarina
Classical and Quantum Gravity | Year: 2010

The Gannon-Lee singularity theorems give well-known restrictions on the spatial topology of singularity-free (i.e. non-spacelike geodesically complete), globally hyperbolic spacetimes. In this paper, we revisit these classic results in the light of recent developments, especially the failure in higher dimensions of a celebrated theorem by Hawking on the topology of black hole horizons. The global hyperbolicity requirement is weakened, and we expand the scope of the main results to allow for the richer variety of spatial topologies which are likely to occur in higher dimensional spacetimes. © 2010 IOP Publishing Ltd.


Bernardes L.S.C.,Federal University of Santa Catarina | Carvalho I.,University of Sao Paulo
Current Medicinal Chemistry | Year: 2013

According to World Health Organization (WHO), trypanosomiasis and leishmaniasis are the most challenging among the neglected tropical diseases. Comparative studies between Leishmania spp and Trypanosoma cruzi have been conducted aiming to find a broad spectrum antiprotozoal agent acting against both parasites. Among the potential molecular target, Trypanothione reductase (TR) is considered an ideal enzyme since it is involved in the unique thiol-based metabolism observed in the Trypanosomatidae family and is a validated target for the search of antitrypanosomatidae drugs. In this review we intend to describe the currently available therapy to treat trypanosomatidae diseases and to highlight important aspects of trypanothione reductase as a target for the search of new and selective inhibitors, such as tricyclic, diphenylsulfide, bicyclic and heterocyclic, polyamine, natural product, N-oxide and nitroheterocyclic, aryl β- aminocarbonyl and α,β-unsaturated carbonyl derivatives. © 2013 Bentham Science Publishers.


Queiroz L.P.,Federal University of Santa Catarina
Headache | Year: 2013

Objective/Background. Some headache syndromes have few cases reported in the literature. Their clinical characteristics, pathogenesis, and treatment may have not been completely defined. They may not actually be uncommon but rather under-recognized and/or underreported. Methods. A literature review of unusual headache syndromes, searching PubMed and ISI Web of Knowledge, was performed. After deciding which disorders to study, relevant publications in scientific journals, including original articles, reviews, meeting abstracts, and letters or correspondences to the editors were searched. Findings. This paper reviewed the clinical characteristics, the pathogenesis, the diagnosis, and the treatment of five interesting and unusual headache syndromes: exploding head syndrome, red ear syndrome, neck-tongue syndrome, nummular headache, and cardiac cephalgia. Conclusions. Recognizing some unusual headaches, either primary or secondary, may be a challenge for many non-headache specialist physicians. It is important to study them because the correct diagnosis may result in specific treatments that may improve the quality of life of these patients, and this can even be life saving. © 2013 American Headache Society.


Weihmann L.,Pontifical Catholic University of Parana | Martins D.,Federal University of Santa Catarina | Dos Santos Coelho L.,Pontifical Catholic University of Parana
Expert Systems with Applications | Year: 2012

The global optimization problem is not easy to solve and is still an open challenge for researchers since an analytical optimal solution is difficult to obtain even for relatively simple application problems. Conventional deterministic numerical algorithms tend to stop the search in local minimum nearest to the input starting point, mainly when the optimization problem presents nonlinear, non-convex and non-differential functions, multimodal and nonlinear. Nowadays, the use of evolutionary algorithms (EAs) to solve optimization problems is a common practice due to their competitive performance on complex search spaces. EAs are well known for their ability to deal with nonlinear and complex optimization problems. The primary advantage of EAs over other numerical methods is that they just require the objective function values, while properties such as differentiability and continuity are not necessary. In this context, the differential evolution (DE), a paradigm of the evolutionary computation, has been widely used for solving numerical global optimization problems in continuous search space. DE is a powerful population-based stochastic direct search method. DE simulates natural evolution combined with a mechanism to generate multiple search directions based on the distribution of solutions in the current population. Among DE advantages are its simple structure, ease of use, speed, and robustness, which allows its application on several continuous nonlinear optimization problems. However, the performance of DE greatly depends on its control parameters, such as crossover rate, mutation factor, and population size and it often suffers from being trapped in local optima. Conventionally, users have to determine the parameters for problem at hand empirically. Recently, several adaptive variants of DE have been proposed. In this paper, a modified differential evolution (MDE) approach using generation-varying control parameters (mutation factor and crossover rate) is proposed and evaluated. The proposed MDE presents an efficient strategy to improve the search performance in preventing of premature convergence to local minima. The efficiency and feasibility of the proposed MDE approach is demonstrated on a force optimization problem in Robotics, where the force capabilities of a planar 3-RRR parallel manipulator are evaluated considering actuation limits and different assembly modes. Furthermore, some comparison results of MDE approach with classical DE to the mentioned force optimization problem are presented and discussed. © 2011 Elsevier Ltd. All rights reserved.


Quincozes-Santos A.,Federal University of Rio Grande do Sul | Bobermin L.D.,Federal University of Rio Grande do Sul | Latini A.,Federal University of Santa Catarina | Wajner M.,Federal University of Rio Grande do Sul | And 3 more authors.
PLoS ONE | Year: 2013

Resveratrol, a polyphenol presents in grapes and wine, displays antioxidant and anti-inflammatory properties and cytoprotective effect in brain pathologies associated to oxidative stress and neurodegeneration. In previous work, we demonstrated that resveratrol exerts neuroglial modulation, improving glial functions, mainly related to glutamate metabolism. Astrocytes are a major class of glial cells and regulate neurotransmitter systems, synaptic processing, energy metabolism and defense against oxidative stress. This study sought to determine the protective effect of resveratrol against hydrogen peroxide (H2O2)-induced cytotoxicity in C6 astrocyte cell line, an astrocytic lineage, on neurochemical parameters and their cellular and biochemical mechanisms. H2O2 exposure increased oxidative-nitrosative stress, iNOS expression, cytokine proinflammatory release (TNFα levels) and mitochondrial membrane potential dysfunction and decreased antioxidant defenses, such as SOD, CAT and creatine kinase activity. Resveratrol strongly prevented C6 cells from H2O2-induced toxicity by modulating glial, oxidative and inflammatory responses. Resveratrol per se increased heme oxygenase 1 (HO1) expression and extracellular GSH content. In addition, HO1 signaling pathway is involved in the protective effect of resveratrol against H2O2-induced oxidative damage in astroglial cells. Taken together, these results show that resveratrol represents an important mechanism for protection of glial cells against oxidative stress. © 2013 Quincozes-Santos et al.


Riboldi B.P.,Federal University of Rio Grande do Sul | Vinhas A.M.,Federal University of Rio Grande do Sul | Moreira J.D.,Federal University of Rio Grande do Sul | Moreira J.D.,Federal University of Santa Catarina
Food Chemistry | Year: 2014

Acrylamide (AA) is a probable human carcinogen found in carbohydrate-rich foods that have been heated to high temperatures. AA dietary exposure has been associated to development of health problems. We perform a systematic review to elucidate the association of dietary AA exposure and human health problems. Articles were screened by reading titles and abstracts before the full text of eligible articles was read (κ = 0.824). Data were harvested by two reviewers and checked by a third. Forty-one articles were analyzed and assessment of dietary exposure proved to be far from uniform and suffered from limitations that possibly impact on the validity of outcomes with relation to human health. Risk assessment of dietary acrylamide exposure is in need of high quality methods for evaluating dietary exposure and validated acrylamide content databases. © 2014 Elsevier Ltd. All rights reserved.


Pereira L.F.A.,Federal University of Rio Grande do Sul | Flores J.V.,Grande Rio University | Bonan G.,Schneider Electric | Coutinho D.F.,Federal University of Santa Catarina | Gomes Da Silva J.M.,Federal University of Rio Grande do Sul
IEEE Transactions on Industrial Electronics | Year: 2014

This paper deals with the synthesis problem of multiple resonant controllers for uninterruptible-power-supply systems in a robust control framework. The controller parameters aiming the tracking of sinusoidal reference signals (with zero steady-state error) and the rejection of harmonic components of the output voltage (when supplying energy to time-varying nonlinear loads) are determined by means of a convex optimization problem subject to a set of linear-matrix-inequality constraints. Results from a 5.0-kVA experimental setup are considered to illustrate and validate the proposed approach. © 1982-2012 IEEE.


Queiroz L.P.,Federal University of Santa Catarina
Current Pain and Headache Reports | Year: 2013

Studying the epidemiology of fibromyalgia (FM) is very important to understand the impact of this disorder on persons, families and society. The recent modified 2010 classification criteria of the American College of Rheumatology (ACR), without the need of tender points palpation, allows that larger and nationwide surveys may be done, worldwide. This article reviews the prevalence and incidence studies done in the general population, in several countries/continents, the prevalence of FM in special groups/settings, the association of FM with some sociodemographic characteristics of the population, and the comorbidity of FM with others disorders, especially with headaches. © 2013 Springer Science+Business Media New York.


Filho V.C.B.,Federal University of Parana | De Campos W.,Federal University of Parana | Lopes A.D.S.,Federal University of Santa Catarina
Revista de Saude Publica | Year: 2012

Objective: To analyze alcohol and tobacco use among Brazilian adolescents and identify higher-risk subgroups. Methods: A systematic review of the literature was conducted. Searches were performed using four databases (LILACS, MEDLINE /PubMed, Web of Science, and Google Scholar), specialized websites and the references cited in retrieved articles. The search was done in English and Portuguese and there was no limit on the year of publication (up to June 2011). From the search, 59 studies met all the inclusion criteria: to involve Brazilian adolescents aged 10-19 years; to assess the prevalence of alcohol and/or tobacco use; to use questionnaires or structured interviews to measure the variables of interest; and to be a school or population-based study that used methodological procedures to ensure representativeness of the target population (i.e. random sampling). Results: The prevalence of current alcohol use (at the time of the investigation or in the previous month) ranged from 23.0% to 67.7%. The mean prevalence was 34.9% (refl ecting the central trend of the estimates found in the studies). The prevalence of current tobacco use ranged from 2.4% to 22.0%, and the mean prevalence was 9.3%. A large proportion of the studies estimated prevalences of frequent alcohol use (66.7%) and heavy alcohol use (36.8%) of more than 10%. However, most studies found prevalences of frequent and heavy tobacco use of less than 10%. The Brazilian literature has highlighted that environmental factors (religiosity, working conditions, and substance use among family and friends) and psychosocial factors (such as confl icts with parents and feelings of negativeness and loneliness) are associated with the tobacco and alcohol use among adolescents. Conclusions: The results suggest that consumption of alcohol and tobacco among adolescents has reached alarming prevalences in various localities in Brazil. Since unhealthy behavior tends to continue from adolescence into adulthood, public policies aimed towards reducing alcohol and tobacco use among Brazilians over the medium and long terms may direct young people and the subgroups at higher risk towards such behavior.


Bastos J.L.,Federal University of Santa Catarina | Faerstein E.,State University of Rio de Janeiro | Celeste R.K.,Federal University of Rio Grande do Sul | Barros A.J.D.,Federal University of Pelotas
Revista de Saude Publica | Year: 2012

Objective: To develop an instrument to assess discrimination effects on health outcomes and behaviors, capable of distinguishing harmful differential treatment effects from their interpretation as discriminatory events. Methods: Successive versions of an instrument were developed based on a systematic review of instruments assessing racial discrimination, focus groups and review by a panel comprising seven experts. The instrument was refined using cognitive interviews and pilot-testing. The final version of the instrument was administered to 424 undergraduate college students in the city of Rio de Janeiro, Southeastern Brazil, in 2010. Structural dimensionality, two types of reliability and construct validity were analyzed. Results: Exploratory factor analysis corroborated the hypothesis of the instrument's unidimensionality, and seven experts verified its face and content validity. The internal consistency was 0.8, and test-retest reliability was higher than 0.5 for 14 out of 18 items. The overall score was higher among socially disadvantaged individuals and correlated with adverse health behaviors/conditions, particularly when differential treatments were attributed to discrimination. Conclusions: These findings indicate the validity and reliability of the instrument developed. The proposed instrument enables the investigation of novel aspects of the relationship between discrimination and health.


de Farias Junior J.C.,Federal University of Paraiba | Lopes A.S.,Federal University of Santa Catarina | Mota J.,University of Porto | Hallal P.C.,Federal University of Pelotas
Revista de Saude Publica | Year: 2012

OBJECTIVE: To estimate the proportion of physically active adolescents and identify associated factors. METHODS: The sample was composed of 2,874 high school students (public and private schools) aged 14 to 19 years in the city of João Pessoa, Northeastern Brazil. Physical activity level was measured by means of a questionnaire and considered physically active if ≥ 300 minutes/week. Sociodemographic variables were analyzed, as well as nutritional status, sedentary behavior, self-report of health status and participation in physical education classes. The prevalence ratio was used as association measure, estimated by means of Poisson regression. RESULTS: The prevalence of physical activity was 50.2% (95%CI: 47.3;53.1). Male adolescents were more physically active than female adolescents (66.3% vs. 38.5%; p<0.001). The factors directly associated with practice of physical activity were: father's higher level of schooling for the male sex and mother's higher level of schooling for the female sex, positive self-reported health status, and participation in physical education classes. CONCLUSIONS: The majority of the adolescents was classifi ed as physically active, particularly the male youths. Adolescents with parents whose level of schooling was higher, with positive health status perception, and who participated in physical education classes were more likely to be physically active.


Castro-Vargas H.I.,National University of Colombia | Rodriguez-Varela L.I.,National University of Colombia | Ferreira S.R.S.,Federal University of Santa Catarina | Parada-Alfonso F.,National University of Colombia
Journal of Supercritical Fluids | Year: 2010

In this work the supercritical fluid extraction (SFE) with carbon dioxide (CO2) and with ethyl acetate (EtAc) and ethanol (EtOH) as co-solvents was applied to obtain the phenolic fraction from guava seeds (Psidium guajava L.). The extraction was explored at various operating conditions, using 10, 20 and 30 MPa and 40, 50 and 60 °C. The use of EtAc and EtOH as co-solvents in SFE was also studied. The supercritical process was compared with traditional techniques such as Soxhlet extraction using EtAc and EtOH as solvents. The quality of the different extracts, obtained using SFE and Soxhlet methods and different solvents, was evaluated through the antioxidant activity, obtained by the collection methods of scavenging DPPH and bleaching of β-carotene, and also through the total phenolic content (TPC) of the samples, by the Folin-Ciocalteu method. The antioxidant potential indicates the use of ethanol as co-solvent as the best modifier in SFE, used in concentration of 10% (w/w) at 50 °C and 30 MPa. The quality of the extracts obtained by SFE with EtOH varied with the operating conditions of temperature and pressure, with higher values obtained at 10 and 20 MPa for TPC results and also antioxidant methods. The process yield of the phenolic fraction was also evaluated for all the extraction procedures studied (SFE and Soxhlet), with results varying from 0.380 to 1.738% (w/w). © 2009 Elsevier B.V. All rights reserved.


Del Duca G.F.,Federal University of Santa Catarina | Thume E.,Federal University of Pelotas | Hallal P.C.,Federal University of Pelotas
Revista de Saude Publica | Year: 2011

Objective: To estimate the prevalence of home care among older adults and to identify associated factors. Methods: Population-based cross-sectional study including 598 individuals aged ≥ 60 years. Subjects were selected through a two-stage cluster sampling strategy in the city of Pelotas, Southern Brazil, between 2007 and 2008. Home care was defined as a positive answer to the following question: "Do you have someone here in your home to take care of you?" Data on potential associated factors for home care were collected using a standardized questionnaire. Poisson regression models with robust variance were used in the crude and in the adjusted analyses. The analysis took into account the clustering of the sample. Results: The prevalence of home care was 49.5% (95%CI: 44.5;54.5). Among those who have a caretaker, 39.5% reported to be cared for by their spouse, while 4.7% of subjects reported having a professional caretaker. In the adjusted analysis, home care was positively associated with male sex, having a partner, increased age and disability for instrumental activities of daily living. Home care was inversely associated with schooling and physical activity levels. Conclusions: The high prevalence of home care observed may overburden family members responsible for the most of the care provided. These findings are important for the planning of health interventions aimed the assistance of the elderly and their families. Particular attention should be paid to individuals with advanced age, low educational level and with disability for activities instrumental to daily living.


Bueno L.,Federal University of Santa Catarina | Dias A.S.,Federal University of Rio Grande do Sul | Steele J.,University College London
Quaternary International | Year: 2013

Between 13,000 and 8000 14C BP, eastern South America was settled by a stable and diversified population of hunter-gatherers. Archaeological excavation in the past twenty years has yielded increasingly consistent evidence of occupation in different regions of Brazil since the end of the Pleistocene, with dates at least contemporary to the Clovis Horizon in North America. This is addressed by documenting and analysing the quantity, quality and distribution of archaeological 14C dates from Brazil during this period. A total of 277 dates from 90 sites are tabulated, mapped, and included in the analysis. During the Late Pleistocene there was a pioneer phase of human colonization, with dispersal inland through the major river systems. Subsequently, the Early Holocene saw the first phase of established settlement of Brazil's interior. There seems to be an archaeological threshold reached at ca. 10,500 years 14C BP: numbers of sites increase, there is evidence of settlement of all major biomes, and there is clear evidence of inter-regional cultural diversity. © 2013 Elsevier Ltd and INQUA.


Garcia-Villarreal O.A.,Federal University of Santa Catarina
Interactive Cardiovascular and Thoracic Surgery | Year: 2015

The Cox-maze III procedure is the gold standard for the surgical treatment of atrial fibrillation. Because of its complexity, this procedure has not been widely accepted by cardiac surgeons. We describe a technique that allows one to work on the mitral valve while more safely performing the standard 'cut-and-sew' Cox-maze III procedure at the same time. © 2015 The Author. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.


Guivant J.S.,Federal University of Santa Catarina
Ambiente e Sociedade | Year: 2016

This article presents the core ideas of Ulrich Beck and his legacy is evaluated. The first part introduces the most widely known concepts, disseminated in the national and international contexts, centered on the works from the period following the publication of his book "Risk Society: Towards a New Modernity". The quest for transforming sociology, both theoretically and methodologically, was a central drive in the approach proposed by Beck, questioning the zombie concepts permeating the area. From social theory, Beck started to significantly influence other areas within the discipline, highlighting environmental sociology and risk theories. The second part presents more recent works, focusing on the cosmopolitanization concept. This is not part of a normative proposal, but rather an analytical one of a process that has seized our contemporary world, largely independently of our intentions. Reading this part of his work is highly relevant to understand both the intellectual and political challenges permeating the complex metamorphoses of our time. The axle of the final part is his last research into climate change and how Beck and his team were facing the need of empirically translating the richness of the sociologist's ideas and insights. Fundamentally, the aim of this article is to highlight how his legacy opens innumerable and creative possibilities of recreating the social sciences field.


Cahan P.,Manton Center for Orphan Disease Research | Cahan P.,Harvard University | Cahan P.,Harvard Stem Cell Institute | Li H.,Rochester College | And 10 more authors.
Cell | Year: 2014

Somatic cell reprogramming, directed differentiation of pluripotent stem cells, and direct conversions between differentiated cell lineages represent powerful approaches to engineer cells for research and regenerative medicine. We have developed CellNet, a network biology platform that more accurately assesses the fidelity of cellular engineering than existing methodologies and generates hypotheses for improving cell derivations. Analyzing expression data from 56 published reports, we found that cells derived via directed differentiation more closely resemble their in vivo counterparts than products of direct conversion, as reflected by the establishment of target cell-type gene regulatory networks (GRNs). Furthermore, we discovered that directly converted cells fail to adequately silence expression programs of the starting population and that the establishment of unintended GRNs is common to virtually every cellular engineering paradigm. CellNet provides a platform for quantifying how closely engineered cell populations resemble their target cell type and a rational strategy to guide enhanced cellular engineering. © 2014 Elsevier Inc.


Bogaerts P.,Biocontrol | Coutinho D.,Federal University of Santa Catarina
Computers and Chemical Engineering | Year: 2014

This paper proposes a robust nonlinear observer for bioreactors combining the classical asymptotic observer and a nonlinear Luenberger-like observer. The resulting hybrid observer considers a new definition of the hybridization parameter which reflects the kinetic model confidence. The nonlinear observer is tuned on the basis of robust H-infinity approach and the differential-algebraic representation (DAR) of nonlinear systems. A simulated case study concerning fed-batch animal cell cultures is presented to demonstrate the potentials and advantages of the proposed approach for state estimation of bioreactors. © 2013 Elsevier Ltd.


Tesser C.D.,Federal University of Santa Catarina | Norman A.H.,Durham University
Saude e Sociedade | Year: 2014

This article presents interpretative hypothesis about the absence of institutional rules for healthcare access to Primary Health Care (PHC) in Brazil, specifically in Family Health Strategy (FHS). Access now is characterized by deviation and/or undervaluation in its operational aspect of providing rapid access to longitudinal clinical care. The hypothesis for this problem has been contextualised along two main axes: SUS institutional norms and the internal debate within the Collective Health field. In the first axis we discuss the North-American influence on Brazilian public health and the understanding of PHC as a “basic package” of healthcare services; the priority given to health promotion in the institutional health policies, as well as the Embracement (the only policy to stimulate the easy access in PHC/FHS) and the sizing of users/FHS team ratio. All that gives support for expanding and resizing the users/FHS ratio. The second axis, discuss Brazil’s relative isolation from the experience of developed countries with strong PHC; the critique of the relationship between biomedicine and capitalism; the emphasis on health promotion and disease prevention as the priority working objectives in PHC/FHS; the distance kept by the academic environment of the reality of FHS services; Brazilian social stratification, which fosters the use of subsidized private health systems by elites and middle classes. Finally, we argue that easy access to longitudinal healthcare should be regarded as fundamental for achieving the four dimensions which must converge into the PHC/FHS action: the ethical-political, anthropological and epidemiological dimensions and the social determinants on health and disease. © 2014, UNIV SAOPAULO. All rights reserved.


da Silva M.L.B.,EMBRAPA - Empresa Brasileira de Pesquisa Agropecuaria | Corseuil H.X.,Federal University of Santa Catarina
International Biodeterioration and Biodegradation | Year: 2012

Groundwater samples from a gasohol contaminated aquifer were analyzed to investigate the effects of nitrate injection on microbial communities associated with benzene, toluene, ethylbenzene and xylenes (BTEX) biodegradation. Real-time quantitative PCR was used to quantify total bacteria (16S rDNA), nitrate-, iron-, sulfate-reducing bacteria and methanogens. Anaerobic BTEX degradation potential was assessed by targeting the bssA gene which encodes for benzylsuccinate synthase (BSS), an enzyme that initiates the biodegradation of toluene and xylenes. Aerobic BTEX biodegradation potential was assessed by targeting the catabolic genes: toluene dioxygenase (TOD), naphthalene dioxygenase (NAH), ring hydroxylating monooxygenase (RMO), phenol hydroxylase (PHE), and/or biphenyl dioxygenase (BPH). 16S rDNA gene copies were higher (∼4×10 5cellsml -1) at the plume centerline coinciding with the highest concentrations of BTEX (∼26mg-totall -1) and ethanol (∼3mgl -1). Regions with high nitrate consumption coincided with the increased nitrate-reducing bacteria population. The establishment of Fe(III)-reducing zones were unlikely associated with bacteria belonging to Geobacter genus. Sulfate-reducing bacteria and methanogens were not detected corroborating with the geochemical footprints. Nitrate did not stimulate the fortuitous growth of anaerobic BTEX degraders as indicated by the absence of bssA amplification. Nitrate alleviated the high biological oxygen demand (BOD) associated with BTEX and ethanol biodegradation thus maintaining microaerophilic niche that supported the growth of aerobic BTEX degraders as indicated by the presence of PHE gene copy numbers (∼2×10 5PHEgenecopiesml -1). Among the genes tested, the non-functional 16S rDNA showed significant correlation (r 2=0.94; p<0.05) with BTEX (but not ethanol) first-order (k') biodegradation rates. Further investigations are required, however, to validate qPCR accuracy and reliability to estimate contaminants removal rates for a wide range of contaminated sites. © 2011 Elsevier Ltd.


Dorea J.G.,University of Brasilia | Farina M.,Federal University of Santa Catarina | Rocha J.B.T.,Federal University of Santa Maria
Journal of Applied Toxicology | Year: 2013

Ethylmercury (etHg) is derived from the metabolism of thimerosal (o-carboxyphenyl-thio-ethyl-sodium salt), which is the most widely used form of organic mercury. Because of its application as a vaccine preservative, almost every human and animal (domestic and farmed) that has been immunized with thimerosal-containing vaccines has been exposed to etHg. Although methylmercury (meHg) is considered a hazardous substance that is to be avoided even at small levels when consumed in foods such as seafood and rice (in Asia), the World Health Organization considers small doses of thimerosal safe regardless of multiple/repetitive exposures to vaccines that are predominantly taken during pregnancy or infancy. We have reviewed in vitro and in vivo studies that compare the toxicological parameters among etHg and other forms of mercury (predominantly meHg) to assess their relative toxicities and potential to cause cumulative insults. In vitro studies comparing etHg with meHg demonstrate equivalent measured outcomes for cardiovascular, neural and immune cells. However, under in vivo conditions, evidence indicates a distinct toxicokinetic profile between meHg and etHg, favoring a shorter blood half-life, attendant compartment distribution and the elimination of etHg compared with meHg. EtHg's toxicity profile is different from that of meHg, leading to different exposure and toxicity risks. Therefore, in real-life scenarios, a simultaneous exposure to both etHg and meHg might result in enhanced neurotoxic effects in developing mammals. However, our knowledge on this subject is still incomplete, and studies are required to address the predictability of the additive or synergic toxicological effects of etHg and meHg (or other neurotoxicants). © 2013 John Wiley & Sons, Ltd.


Kneur J.-L.,CNRS Charles Coulomb Laboratory | Pinto M.B.,Federal University of Santa Catarina
Physical Review Letters | Year: 2016

We use the scalar model with quartic interaction to illustrate how a nonperturbative variational technique combined with renormalization group (RG) properties efficiently resums perturbative expansions in thermal field theories. The resulting convergence and scale dependence of optimized thermodynamical quantities, here illustrated up to two-loop order, are drastically improved as compared to standard perturbative expansions, as well as to other related methods such as the screened perturbation or (resummed) hard-thermal-loop perturbation, that miss RG invariance (as we explain). Being very general and easy to implement, our method is a potential analytical alternative to dealing with the phase transitions of field theories such as thermal QCD. © 2016 American Physical Society.


de Souza J.G.,Federal University of Santa Catarina
Quintessence international (Berlin, Germany : 1985) | Year: 2013

To assess the impact of local and systemic factors on additional peri-implant bone loss. From a total of 253 patients, 193 were selected (126 women) and restored with 722 implants, in place for at least 1 year. Patients had previously attended the supportive periodontal/peri-implant therapy program at the Department of Implant Dentistry at the Federal University of Santa Catarina, Brazil. The study was divided according to physiologic (PBL < 2 mm) or additional bone loss (ABL >= 2 mm) evaluated from the time of prosthesis placement to the reassessment visit. Data collection and analysis included evaluation of systemic factors, such as history of periodontal disease, heart disease, hypertension, diabetes mellitus, hyperthyroidism/hypothyroidism, osteoporosis, kidney disease, alcohol abuse, smoking habits, chemotherapy, radiation therapy, menopause, and hormone replacement. Analysis of local factors included implant platform, diameter, location, time in function, and type of prosthesis. No systemic factors influenced ABL (P > .05). Considering local factors, only time in function and type of prosthesis influenced ABL (P < .05). Fixed partial dental prostheses and full-arch fixed prostheses present higher rates of ABL. In addition, all types of prostheses showed greater ABL when in function for more than 4 years.


This study aimed to understand the nurses' contributions in the network of relationships and interactions of community health workers (CHW) in a city located in the south of the country. The Grounded Theory was used and twenty individuals were interviewed, among health professionals and users of the health center, divided into three sample groups. The nurse is recognized as a key element in the network of relationships and interactions of the CHW with the community, being viewed as a leader. Although showing signs of an authoritarian leadership, the nurse promotes dialogue and acts as a facilitator of teamwork in health promotion. It was concluded that the nurses of the Family Health Strategy have a significant role in the health team, providing clinical support to organize the care, and management, to foster good relations, direct the activities and conduct the flow of information.


Junior O.C.A.,Santa Catarina State University | Rabelo R.J.,Federal University of Santa Catarina
International Journal of Networking and Virtual Organisations | Year: 2013

This paper presents an exploratory and qualitative work of a novel model for the selection of the most adequate logistics providers to compose virtual organisations. It includes a performance measurement model and a supporting methodology that considers the intrinsic dynamics, autonomy and temporality of virtual organisations, involving both intra and inter-organisational strategic indicators. The model is flexible in terms of both allowing performance indicator weight relaxation and being adapted according to the organisation's governance model. A software prototype was developed and interviews with specialists were carried out to evaluate the model. Results are discussed at the end. Copyright © 2013 Inderscience Enterprises Ltd.


Kurzawe F.,Federal University of Rio Grande do Sul | Iannuzzi R.,Federal University of Rio Grande do Sul | Merlotti S.,Federal University of Santa Catarina | Rohn R.,Sao Paulo State University
Review of Palaeobotany and Palynology | Year: 2013

This is the second contribution on the Permian permineralized flora of the Parnaíba Basin, NE Brazil that focuses on the gymnosperm woods from the Motuca Formation. We describe five new species of gymnospermous woods Damudoxylon buritiranaense sp. nov., Damudoxylon humile sp. nov., Damudoxylon roessleri sp. nov., Kaokoxylon punctatum sp. nov. and Taeniopitys tocantinensis sp. nov., and one new form, Taeniopitys sp. 1. The woods vary widely in their anatomy, mainly in their pith features, from simple parenchymatic to solenoid piths with canals and ducts, as well as different cells, such as secretory and sclerenchymatic ones. However, they have one characteristic in common - araucarian pitting in the radial walls of the tracheids. © 2013 Elsevier B.V.


Fiaschi P.,Federal University of Santa Catarina
Brittonia | Year: 2016

Abstract. Dendropanax fluminensis, a new species of Araliaceae from the Atlantic Forest of Rio de Janeiro state, Brazil, is here described and illustrated. It is compared with morphologically similar species from the Brazilian Atlantic Forest, especially D. monogynus, from which it can be distinguished by the inflorescences with 2–5 secondary axes, shorter pedicels in flower and in fruit, and 3- or 4-carpellate ovaries. The new species has been found in lowland rainforests from sea-level to about 200 m elevation in the central portion of Rio de Janeiro state. Information on the geographic distribution, habitat preferences, and conservation status according with IUCN Red List categories and criteria are also presented. © 2016 The New York Botanical Garden


Castro L.B.,Federal University of Santa Catarina | Castro L.B.,Federal University of Maranhao | De Oliveira L.P.,University of Sao Paulo
Advances in High Energy Physics | Year: 2014

We point out a misleading treatment in the recent literature regarding analytical solutions for nonminimal vector interaction for spin-one particles in the context of the Duffin-Kemmer-Petiau (DKP) formalism. In those papers, the authors use improperly the nonminimal vector interaction endangering in their main conclusions. We present a few properties of the nonminimal vector interactions and also present the correct equations to this problem. We show that the solution can be easily found by solving Schrödinger-like equations. As an application of this procedure, we consider spin-one particles in presence of a nonminimal vector linear potential. © 2014 L. B. Castro and L. P. de Oliveira.


The objective of this research is to analyze the financial results of companies of the away-from-home food supply service segment, and disclose this analysis so that it could be a source of information to assist in the preparation of the strategic and financial planning of such companies. To this end, the following specific objectives were defined: to develop a statement of income and expenditure (SIE) per company surveyed; to calculate the main financial indicators of these companies, such as profitability, cost of goods sold (COGS), average wages, labor costs, real estate occupancy, and taxation; to verify the average consumption per customer (food allowance); to identify the correlation between the various types of costs and financial results; and to analyze the main financial reasons causing negative results among the companies that responded to the survey. Regarding the methodological procedures, the present study is characterized as a descriptive and quantitative research. The data were collected by means of electronic questionnaires applied to 126 commercial establishments located in the municipality of Florianopolis, affiliated to the Brazilian Association of Bars and Restaurants (ABRASEL), in 2013. Concerning the results, the research achieved its previously described specific goals, with emphasis on the percentage of loss-making companies (27%); minimum correlation between salary level and employee turnover; and strong negative correlation between fixed costs and financial results. This research is important because there is no published information on the financial results of companies of this sector, and it will serve to guide entrepreneurs in the planning of companies from this segment.


Lourenco E.M.,Federal University of Parana | Costa A.S.,Federal University of Santa Catarina | Ribeiro Jr. R.,Federal University of Parana
IEEE Transactions on Power Systems | Year: 2010

This paper extends the conventional power flow formulation in order to enable the solution of networks modeled at the bus section level. The proposed extension is centered on a methodology to represent zero impedance branches successfully employed in state estimation studies. Accordingly, the active and reactive power flows through switches and circuit breakers are treated as new state variables along with the complex voltage at the network nodes. Information regarding device statuses is included into the power flow problem as new (and linear) equations, producing a solvable non-redundant set of algebraic equations. Applications of the proposed modifications in connection with the power flow solution via Newton-Raphson's method are presented and discussed. The proposed approach provides an efficient tool to directly determine the power flow distribution over selected substations of the network, avoiding unreliable artifices and tedious post-processing procedures required when a conventional power flow formulation is applied. The IEEE 24-bus and IEEE 30-bus test systems are employed to illustrate and evaluate the proposed approach, considering distinct substation layouts. © 2009 IEEE.


Philpott A.,University of Auckland | De Matos V.,Plan4 Engineering SS | Finardi E.,Federal University of Santa Catarina
Operations Research | Year: 2013

We consider a class of multistage stochastic linear programs in which at each stage a coherent risk measure of future costs is to be minimized. A general computational approach based on dynamic programming is derived that can be shown to converge to an optimal policy. By computing an inner approximation to future cost functions, we can evaluate an upper bound on the cost of an optimal policy, and an outer approximation delivers a lower bound. The approach we describe is particularly useful in sampling-based algorithms, and a numerical example is provided to show the efficacy of the methodology when used in conjunction with stochastic dual dynamic programming. © 2013 INFORMS.


Normey-Rico J.E.,Federal University of Santa Catarina | Guzman J.L.,University of Almeria
Industrial and Engineering Chemistry Research | Year: 2013

This paper presents a unified approach, which is based on a PID approximation of the filtered Smith predictor, for tuning PID controllers for stable, integrative, and unstable dead-time processes. The proposed control tuning method is simple to analyze and use. Case studies are included to illustrate the advantages of the proposed tuning rules. Comparisons with other existing methods are also presented to show that the proposed unified method provides promising results. Furthermore, tuning rules to obtain a reasonable trade-off between robustness and performance are derived. © 2013 American Chemical Society.


Costa P.,University of Coimbra | Ferreira M.,University of Coimbra | Menezes D.P.,Federal University of Santa Catarina | Moreira J.,University of Coimbra | Providencia C.,University of Coimbra
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2015

The effect of a strong magnetic field on the location of the critical end point (CEP) in the QCD phase diagram is discussed under different scenarios. In particular, we consider the contribution of the vector interaction and take into account the inverse magnetic catalysis obtained in lattice QCD calculations at zero chemical potential. The discussion is realized within the (2+1) Polyakov-Nambu-Jona-Lasinio model. It is shown that the vector interaction and the magnetic field have opposite competing effects, and that the winning effect depends strongly on the intensity of the magnetic field. The inverse magnetic catalysis at zero chemical potential has two distinct effects for magnetic fields above 0.3GeV2: it shifts the CEP to lower chemical potentials, hinders the increase of the CEP temperature and prevents a too large increase of the baryonic density at the CEP. For fields eB<0.1GeV2 the competing effects between the vector contribution and the magnetic field can move the CEP to regions of temperature and density in the phase diagram that could be more easily accessible to experiments. © 2015 American Physical Society.


Taneja I.J.,Federal University of Santa Catarina
Information (Switzerland) | Year: 2013

Jensen-Shannon, J-divergence and Arithmetic-Geometric mean divergences are three classical divergence measures known in the information theory and statistics literature. These three divergence measures bear interesting inequality among the three non-logarithmic measures known as triangular discrimination, Hellingar's divergence and symmetric chi-square divergence. However, in 2003, Eve studied seven means from a geometrical point of view, which are Harmonic, Geometric, Arithmetic, Heronian, Contra-harmonic, Root-mean square and Centroidal. In this paper, we have obtained new inequalities among non-negative differences arising from these seven means. Correlations with generalized triangular discrimination and some new generating measures with their exponential representations are also presented. © 2013 by the authors; licensee MDPI, Basel, Switzerland.


Schlindwein-Zanini R.,Federal University of Santa Catarina
Revista Neurociencias | Year: 2010

In the elderly, the individual changes over time (physical, psychological, social and neuropsychological aspects) and according to his/her environment. In aged people the high incidence of depression and dementias can bring deficits in cognition, memory, language, executive functions, praxias and gnosias, intervening in their autonomy, and in their social and professional performance. Thus, it is important to carry out studies on this theme. Objective. A literature review of the neuropsychological aspects of the elderly and their neuropsychological evaluation, especially those which relate to dementias, was carried out. Method. Literature review. Research in the following bases of data Bireme, Scielo e Pubmed. And books and teses. Conclusion. A neuropsychological evaluation is recommended, mainly, in the identification of cognitive decline in the elderly, in the evaluation of the impairment of cerebral areas in the case of neurological alterations, in the differential diagnosis of psychological/psychiatric and neurological syndromes; and in guiding a rehabilitation intervention.


Horewicz V.V.,Federal University of Santa Catarina
The International journal of oral & maxillofacial implants | Year: 2013

The host response to infection differs between peri-implantitis and periodontitis, but the mechanisms underlying these differences are not understood. In this study, the distribution of dendritic cell subpopulations in healthy peri-implant mucosa (HPIM) was compared to that of healthy gingiva (HG). HPIM and HG specimens were obtained from nonsmoking, systemically healthy subjects. Immunohistochemistry was used to quantify the number of Langerhans cells (LCs) (CD1a+) and interstitial dendritic cells (IDCs) (factor XIIIa+) in the oral epithelium, sulcular/junctional epithelia, and lamina propria without inflammatory infiltration and with inflammatory infiltration. Fourteen HPIM and 13 HG specimens were obtained from subjects aged 29 to 55 years. The lamina propria of the HPIM had fewer LCs than that of the HG (HPIM: 7.99 ± 10.76, HG: 25.68 ± 16.98; P = .003). There was no significant difference in the number of CD1a+ cells in the oral epithelium or the sulcular/junctional epithelia between the HPIM and the HG (P ≥ .23). A greater number of IDCs was observed in the lamina propria with inflammatory infiltration of the HPIM compared to the HG (HPIM: 57.02 ± 35.70, HG: 33.89 ± 26.98; P = .06). In the lamina propria of HPIM, fewer LCs and more IDCs were observed. These differences may be associated with reduced stimulation of the innate and acquired immune responses initiated by LCs and the greater matrix remodeling of peri-implant tissue associated with IDCs.


Restrepo A.,Technological University of Pereira | Bazzo E.,Federal University of Santa Catarina | Miyake R.,Tractebel Engineering
Journal of Cleaner Production | Year: 2015

This paper presents the first results concerning a life cycle assessment of the energetic coal obtained from a southern Brazil underground mine, through the rooms and pillars technique, and used for electric power generation. The main purpose was to identify, according to the technology in question, the environmental impacts associated with the production of 1 kg of energetic coal. Two methods of assessment were considered: the Eco-indicator 99 analyzing five environmental categories: carcinogens, respiratory inorganics, ecotoxicity, acidification and land use, and the Intergovernmental Panel on Climate Change, focusing in global warming category over 100 years. The life cycle inventory was obtained from data collected in situ during coal mining and its beneficiation process. Short and long term scenarios were analyzed. In case of long term, due to the highest contribution of tailings, the weighting showed that the carcinogens category was the most representative, followed by respiratory inorganics, land use and ecotoxicity categories. For short term, the respiratory inorganics was found as the most representative category, with important contributions of explosives, electricity and diesel consumption. For both scenarios, the global warming potential index showed 0.0856 kg of CO2-eq per kg of energetic coal, which is a low value when compared with reported values for similar processes. © 2014 Elsevier Ltd. All rights reserved.


Pimenta F.M.,Federal University of Santa Catarina | Assireu A.T.,Federal University of Itajuba
Renewable Energy | Year: 2015

A wind-hydro hybrid system is proposed to improve Brazil's use of its renewable energy portfolio. In this scheme, winds from local or remote locations supply extra generation, so that the hydroelectric outflow can be reduced accordingly to wind production. The water savings, in turn, lead to a significant improvement of the reservoir's storage. A simple model is developed and applied to the Itumbiara hydroelectric reservoir of midwest Brazil. Scenarios for different wind contributions are compared to historical observations from 1994 to 2011. Results suggest that, if implemented, the hybrid system should improve the country's energy security. Hydroelectric reservoirs might be able to confront interannual climate variability without risks to the energy supply. A positive impact on the multiple use of reservoirs is expected for fish-farming, irrigation, recreation, navigation and water supply. © 2014 Elsevier Ltd.


Gomes W.J.S.,Federal University of Santa Catarina
12th International Conference on Applications of Statistics and Probability in Civil Engineering, ICASP 2015 | Year: 2015

When dealing with structural risk optimization by means of Monte Carlo simulation methods, the total expected cost usually becomes a noisy function and it is not possible to directly calculate its derivatives. In fact, even the estimation of these derivatives becomes a challenging task. On the other hand, gradient-based optimization methods are among the most efficient ones for this kind of problem, but they require derivatives. In this paper, a new method, which allows estimating gradients of the total expected cost with respect to design variables, is used to perform risk optimization of trusses by a gradient-based optimization method. The proposed methodology is employed in the solution of a bi-dimensional and a spatial truss. The results show that this methodology presents a significantly smaller computational cost when compared to a similar procedure using finite differences and indicates that the quality of the gradients is slightly better as well.


Lettnin D.,Federal University of Santa Catarina
LATS 2016 - 17th IEEE Latin-American Test Symposium | Year: 2016

The amount of embedded software present in our daily routines has been increasing with more electronic devices being introduced in many different areas. As a consequence, concerns with safety and reliability has led to the development of a series of mechanisms for verification and design of such systems. Although Bounded model checking (BMC), for example, has received much attention lately, practical use might be restricted, considering systems complexity. In this paper, we show a methodology for combining BMC with Electronic System Level Design and Virtual Platforms. Our approach has the potential to improve system level verification, through simulation, and to accelerate the development process with Virtual Platforms. © 2016 IEEE.


Pinto M.B.,Federal University of Santa Catarina | Koch V.,Lawrence Berkeley National Laboratory | Randrup J.,Lawrence Berkeley National Laboratory
Physical Review C - Nuclear Physics | Year: 2012

The surface tension of quark matter plays a crucial role for the possibility of quark matter nucleation during the formation of compact stellar objects, because it determines the nucleation rate and the associated critical size. However, this quantity is not well known and the theoretical estimates fall within a wide range, γ 0 5-300MeV/fm2. We show here that once the equation of state is available one may use a geometrical approach to obtain a numerical value for the surface tension that is consistent with the model approximations adopted. We illustrate this method within the two-flavor linear σ model and the Nambu-Jona-Lasinio model with two and three flavors. Treating these models in the mean-field approximation, we find γ 0 7-30MeV/fm2. Such a relatively small surface tension would favor the formation of quark stars and may thus have significant astrophysical implications. We also investigate how the surface tension decreases towards zero as the temperature is raised from zero to its critical value. © 2012 American Physical Society.


Scaratti D.,University of West Santa Catarina | Calvo M.C.M.,Federal University of Santa Catarina
Revista de Saude Publica | Year: 2012

OBJECTIVE: To develop a composite indicator to evaluate the quality of municipal management of primary health care. METHODS: The evaluation model focuses on aspects of health system management. Fifty-fi ve performance indicators were used and classifi ed according to the criteria of relevance, effectiveness, effi cacy and effi ciency. The measures were aggregated through an additive data envelopment analysis model for measures of value, merit and quality. Data was utilized from 36 municipalities in Santa Catarina State (Southern Brazil), with populations between 10 thousand and 50 thousand residents in 2006. RESULTS: The results are presented as monotonic measures over the interval [0, 1] (score = 1: effi cient; other values: ineffi cient). Five municipalities had a score of 1 in the quality of management for actions promoting access, while eight municipalities received a score of 1 in the quality of management of actions for service provision; the other municipalities were classifi ed as ineffi cient (score < 1) for both dimensions. CONCLUSIONS: The quality of municipal management in primary health care can be evaluated with a composite indicator, constructed through linear programming techniques, which simultaneously considers the criteria of relevance, effectiveness, effi cacy and effi ciency and expresses them as measures of value, merit and quality.


Kirby A.J.,University of Cambridge | Nome F.,Federal University of Santa Catarina
Accounts of Chemical Research | Year: 2015

Conspectus Historically, the chemistry of phosphate transfer - a class of reactions fundamental to the chemistry of Life - has been discussed almost exclusively in terms of the nucleophile and the leaving group. Reactivity always depends significantly on both factors; but recent results for reactions of phosphate triesters have shown that it can also depend strongly on the nature of the nonleaving or "spectator" groups. The extreme stabilities of fully ionised mono- and dialkyl phosphate esters can be seen as extensions of the same effect, with one or two triester OR groups replaced by O-. Our chosen lead reaction is hydrolysis-phosphate transfer to water: because water is the medium in which biological chemistry takes place; because the half-life of a system in water is an accepted basic index of stability; and because the typical mechanisms of hydrolysis, with solvent H2O providing specific molecules to act as nucleophiles and as general acids or bases, are models for reactions involving better nucleophiles and stronger general species catalysts. Not least those available in enzyme active sites.Alkyl monoester dianions compete with alkyl diester monoanions for the slowest estimated rates of spontaneous hydrolysis. High stability at physiological pH is a vital factor in the biological roles of organic phosphates, but a significant limitation for experimental investigations. Almost all kinetic measurements of phosphate transfer reactions involving mono- and diesters have been followed by UV-visible spectroscopy using activated systems, conveniently compounds with good leaving groups. (A "good leaving group" OR∗is electron-withdrawing, and can be displaced to generate an anion R∗O- in water near pH 7.) Reactivities at normal temperatures of P-O-alkyl derivatives - better models for typical biological substrates - have typically had to be estimated: by extended extrapolation from linear free energy relationships, or from rate measurements at high temperatures.Calculation is free from these limitations, able to handle very slow reactions as readily as very fast ones, and capable of predicting rate constants with levels of accuracy acceptable to the experimentalist. We present an updated overview of phosphate transfer, with particular reference to the mechanisms of the reactions of alkyl derivatives and triesters. The intention is to present a holistic (not comprehensive!) overview of the reactivity of typical phosphate esters, in terms familiar to the working chemist, at a level sufficient to support informed predictions of reactivity for structures of interest. © 2015 American Chemical Society.


This study aimed to highlight and analyze the nurses' practices in care management described in the scientific production in Brazil and internationally, through an integrative review. It was examined articles published between 2005 and 2010, in the LILACS, SciELO, BDENF and CINAHL databases, with the descriptors Management and Administration, in conjunction with Care and Nursing, and the terms Nursing Management and Nursing Care, totaling 27 publications. The management of care performed by nurses is directly related to the search for quality care and better working conditions through actions such as: care realization, human and material resources management, leadership, assistance planning, nursing team training, care coordination and evaluation of nursing actions.


Amestoy S.C.,Federal University of Santa Catarina
Revista brasileira de enfermagem | Year: 2010

The aim of this study is make a theorical-reflection about the importance of using dialogical leadership in hospital institutions through Freirean referencial. The dialogical leadership pattern differs from the coercive and autocratic methods, for being reasoned on the establishment of an efficient communicational process, able to stimulate autonomy, co-responsibility and appreciation of each member from nurse team. The dialogical leadership, unlike the directive one, is a management instrument, that pursuits to minimize the conflicts and stimulate the formation of healthy interpersonal relationships, which can contribute to the improvement of organizational atmosphere and quality care provided to health services users.


Timmer W.,CRS Clinical Research Services Mannheim GmbH | Moroni-Zentgraf P.,Boehringer Ingelheim | Cornelissen P.,Boehringer Ingelheim | Unseld A.,Boehringer Ingelheim | And 2 more authors.
Respiratory Medicine | Year: 2015

Introduction: Once-daily tiotropium Respimat® 5 μg is an efficacious add-on therapy to inhaled corticosteroids (ICS) with or without long-acting β2-agonists in patients with symptomatic asthma. The objective of this study was to investigate whether the dosing regimen of tiotropium (once- versus twice-daily), delivered via the Respimat® SoftMist™ inhaler, affected 24-h bronchodilator efficacy and safety versus placebo Respimat® in patients with asthma who were symptomatic despite medium-dose ICS therapy. Methods: A randomised, double-blind, placebo-controlled, crossover study with 4-week treatment periods of tiotropium 5 μg (once-daily, evening) and 2.5 μg (twice-daily, morning and evening). The primary efficacy end point was forced expiratory volume in 1 s (FEV1) area under the curve from 0 to 24 h (AUC)(0-24h) at the end of each treatment period. Secondary end points included peak forced expiratory volume in 1 s measured within 24 h of the last evening inhalation (peak FEV1(0-24h)), trough FEV1 measured prior to evening dosing, morning and evening peak expiratory flow (PEFam and PEFpm) and pharmacokinetic assessments. Results: 94 patients were randomised (mean age 44.3 years; mean asthma duration 21.3 years) and 89 (94.7%) completed the study. Significant and comparable bronchodilation was achieved over a 24-h period with both tiotropium dosing regimens. FEV1 AUC(0-24h) response (mean ± standard error) was significantly greater with both tiotropium dosing regimens (once-daily 5 μg: 158 ± 24 mL; twice-daily 2.5 μg; 149 ± 24 mL; both p < 0.01) when compared with placebo. Improvements in peak FEV1(0-24h), trough FEV1 and pre-dose PEFam/pm with both dosing regimens versus placebo were statistically significant (all p < 0.01), with no statistically significant differences between the tiotropium treatment regimens. Total systemic exposure and tolerability were comparable between treatment regimens. Conclusions: Lung function improvements with tiotropium Respimat® add-on to medium-dose ICS were sustained and similar for once-daily 5 μg and twice-daily 2.5 μg, supporting tiotropium Respimat® 5 μg as a once-daily bronchodilator that provides efficacy over the whole 24-h dosing interval in patients with symptomatic asthma. ClinicalTrials.gov identifier: NCT01152450. © 2015 The Authors.


This study aims to present the application of the Method of Paulo Freire in a research with professionals of family health teams, users and community leaders about the use of the notion of health promotion. It describes how to obtain and analyze data in the Culture Circles performed in three phases: thematic research, coding /decoding and unveiling critical. This methodology contributed reflections of health practices of participants, allowing alternatives to transform them. The theoretical limits for their payment, among them the difficulty of deconstruction of the authoritarian conferred by the power of professional knowledge.


Petronilho S.,University of Aveiro | Maraschin M.,Federal University of Santa Catarina | Coimbra M.A.,University of Aveiro | Rocha S.M.,University of Aveiro
Industrial Crops and Products | Year: 2012

Medicinal plant research is universally on the rise. Researchers, as well as the general public, recognize that natural products, predominantly those derived from plants, may exhibit health benefits. The tendency is to consider natural products as non-toxic and presenting fewer side effects than those used by conventional medicine. However, information concerning the real human health benefits of natural products is yet seldom available, which is a drawback for their possible valuation. Chamomile is one of the most widely used medicinal plants and its sesquiterpenic-related products are an example of this informative weakness. Several health benefits have been claimed for chamomile extracts and for a large number of sesquiterpenic compounds known to occur in chamomile. However, a deep knowledge concerning the compounds responsible for each specific effect, as well as the mechanisms behind them has not been stated, or, if it exists, is dispersed in literature. Thus, this review comprises a deep survey on the reported potential health benefits of chamomile-related sesquiterpenic compounds, and takes into account the models used for their evaluation: in vitro or in vivo. In spite of the relevance of the in vitro and animal studies reported in literature, where the data obtained are very promising concerning the potential health benefits of chamomile-related sesquiterpenic compounds, their extension to human trials is essential. Several aspects related to this actual challenge are discussed. © 2012 Elsevier B.V.


Restrepo A.,Technological University of Pereira | Bazzo E.,Federal University of Santa Catarina
Renewable Energy | Year: 2016

An exergy approach to environmental impacts is proposed as an exergoenvironmental analysis methodology to be applied in a power plants modified for burning in a co-firing process, including external impacts originated from the routes of the coal and the biomass. A new Global Greenhouse Gases (iGHG Global) index is also presented in order to compare different co-firing scenarios. The methodology took into account the global warming impact category using the Global Warming Potential (GWP) index. The operating details were obtained from an existing 50 MWe PC power plant. Two scenarios were analyzed: (A) burning only pulverized coal; and (B) burning pulverized coal and rice straw in a co-firing process. The results showed a total of exergoenvironmental impact of 16.43 kg CO2-eq/s for scenario A and 12.3 kg CO2-eq/s for scenario B, that is, around 25.13% lower. In relation with the exergoenvironmental performance variables, the steam generator showed the highest environmental impact associated with the exergy destruction (B ˙D,k). Also, when scenario B was considered, the relative difference of specific environmental impact (rb,k) shows an important reduction around 30% lower in the steam generator. The (iGHG Global) index indicated values of 0.5 to scenario A and 0.564 to the scenario B. © 2016 Elsevier Ltd.


Paduani C.,Federal University of Santa Catarina
Physica E: Low-Dimensional Systems and Nanostructures | Year: 2016

Calculations using density functional theory are performed to study supramolecular assemblage of high spin halide complexes based on the gadolinium chloride. With the addition of Cl atoms to both Gd and B in number that exceeds their formal valence by 1 the calculated vertical detachment energy increases to 6.08 and 5.57 eV in GdCl4 and BCl4, respectively, indicating superhalogen behavior. By using BCl4 and GdCl4 clusters as building blocks to decorate the Gd atom the vertical detachment energy increases to 7.12 and 7.70 eV in the anionic clusters Gd(BCl4)4 - and Gd(GdCl4)4 -, respectively, which is indicative of hyperhalogen behavior. High spin multiplicities in the ferromagnetic state are observed for these clusters indicating therein outstanding paramagnetic response. © Elsevier B.V. All rights reserved.


Prediger R.D.S.,Federal University of Santa Catarina
Journal of Alzheimer's Disease | Year: 2010

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting approximately 1% of the population older than 60 years. Classically, PD is considered to be a motor system disease and its diagnosis is based on the presence of a set of cardinal motor signs (rigidity, bradykinesia, rest tremor) that are consequence of a pronounced death of dopaminergic neurons in the substantia nigra pars compacta. Nowadays there is considerable evidence showing that non-dopaminergic degeneration also occurs in other brain areas which seems to be responsible for the deficits in olfactory, emotional and memory functions that precede the classical motor symptoms in PD. The present review attempts to examine results reported in epidemiological, clinical and animal studies to provide a comprehensive picture of the antiparkinsonian potential of caffeine. Convergent epidemiological and pre-clinical data suggest that caffeine may confer neuroprotection against the underlying dopaminergic neuron degeneration, and influence the onset and progression of PD. The available data also suggest that caffeine can improve the motor deficits of PD and that adenosine A2A receptor antagonists such as istradefylline reduces OFF time and dyskinesia associated with standard 'dopamine replacement' treatments. Finally, recent experimental findings have indicated the potential of caffeine in the management of non-motor symptoms of PD, which do not improve with the current dopaminergic drugs. Altogether, the studies reviewed provide strong evidence that caffeine may represent a promising therapeutic tool in PD, thus being the first compound to restore both motor and non-motor early symptoms of PD together with its neuroprotective potential. © 2010 IOS Press and the authors. All rights reserved.