Federal University of Pernambuco

Recife, Brazil

Federal University of Pernambuco is a public university located in Recife, Brazil, established in 1946. UFPE has 70 undergraduate courses and 175 postgraduate courses. As of 2007, UFPE had 35,000 students and 2,000 professors. The university has three campi: Recife, Vitória de Santo Antão, and Caruaru. Its main campus, or "Cidade Universitária", has 10 centers in 149 hectares. It is located in the west part of Recife, in the Várzea neighborhood. The Law School or Faculty of Law is located downtown. UFPE ranks among the top Brazilian universities, being the ninth university both in size and scientific production, and the seventh among the federal institutes. UFPE's Center for Exact and Natural science is consistently the strongest in research production in the university. CAPES ratings are Physics Department , the Center of Informatics and the Chemistry Department .UFPE has been elected twice as the best university of north and northeast Brazil by Guia do Estudante and Banco Real .Each year over 6,000 seats are offered in a competitive entry exam . The median and average competition rate is of about 10 applicants for each seat. Wikipedia.

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Santos-Magalhaes N.S.,Federal University of Pernambuco | Mosqueira V.C.F.,Federal University of Ouro Preto
Advanced Drug Delivery Reviews | Year: 2010

Despite the fact that we live in an era of advanced technology and innovation, infectious diseases, like malaria, continue to be one of the greatest health challenges worldwide. The main drawbacks of conventional malaria chemotherapy are the development of multiple drug resistance and the non-specific targeting to intracellular parasites, resulting in high dose requirements and subsequent intolerable toxicity. Nanosized carriers have been receiving special attention with the aim of minimizing the side effects of drug therapy, such as poor bioavailability and the selectivity of drugs. Several nanosized delivery systems have already proved their effectiveness in animal models for the treatment and prophylaxis of malaria. A number of strategies to deliver antimalarials using nanocarriers and the mechanisms that facilitate their targeting to Plasmodium spp.-infected cells are discussed in this review. Taking into account the peculiarities of malaria parasites, the focus is placed particularly on lipid-based (e.g., liposomes, solid lipid nanoparticles and nano and microemulsions) and polymer-based nanocarriers (nanocapsules and nanospheres). This review emphasizes the main requirements for developing new nanotechnology-based carriers as a promising choice in malaria treatment, especially in the case of severe cerebral malaria. © 2009 Elsevier B.V. All rights reserved.

Schiel N.,Federal Rural University of Pernambuco | Souto A.,Federal University of Pernambuco
Developmental Neurobiology | Year: 2017

Callithrix jacchus are small-bodied Neotropical primates popularly known as common marmosets. They are endemic to Northeast Brazil and occur in contrasting environments such as the humid Atlantic Forest and the dry scrub forest of the Caatinga. Common marmosets live in social groups, usually containing only one breeding pair. These primates have a parental care system in which individuals help by providing assistance to the infants even when they are not related to them. Free-ranging groups use relatively small home ranges (0.5–5 hectares) and have an omnivorous diet. Because of the shape of their teeth, they actively gouge tree bark to extract and consume exudates. When foraging for live prey, they adjust their strategy according to the type of prey. The successful use of appropriate hunting strategies depends not only on age but also on prey type and seems to be mediated by learning and experience. Indeed, common marmosets have shown unexpected cognitive abilities, such as true imitation. All these aspects seem to have contributed to the ecological success of this species. Callithrix jacchus has been widely studied, especially in captivity; even so, a number of questions remain to be answered about its biology, ecology, and behavior, both in captivity and the wild. A richer understanding of marmosets' natural behavior and ecology can have a significant impact on shaping ongoing and future neuroscience research. © 2016 Wiley Periodicals, Inc. Develop Neurobiol 77: 244–262, 2017. © 2016 Wiley Periodicals, Inc.

U-Pb zircon ages of igneous and metaigneous rocks in orogenic belts provide important information concerning the occurrence and duration of magmatic and metamorphic events whereas detrital zircon ages of metasedimentary sequences place constrains on the sources and deposition ages of supracrustal rocks. With these data, it is possible to compare and establish correlations between different provinces or between domains of the same province. A sufficiently large dataset of U-Pb ages is now available from the Borborema Province, northeastern Brazil, allowing the use of statistical methods to identify age peaks. 210 U-Pb crystallization ages from magmatic rocks and ca. 2300 U-Pb zircon ages of detrital grains from metasedimentary rocks were compiled. The igneous age spectrum shows two large age clusters. The first spans about 300Ma, from 2.25Ga to 1.97Ga. Orthogneissic complexes in the Rio Grande do Norte Domain have ages mainly between 2.22 and 2.15Ga whereas in the remainder of the province they more commonly range from 2.18 to 2.0Ga. The long duration of this magmatism is comparable to that of Neoproterozoic and Phanerozoic accretionary/collisional orogens and is inferred to have resulted from amalgamation of preexisting crustal blocks and juvenile material to the active margin of the Rio Grande do Norte Domain. The other large cluster of ages is much narrower, from 650Ma to 550Ma, which is more consistent with the duration of orogenesis in collisional belts. Orogenic granitoids older than 600Ma were not yet identified in the Rio Grande do Norte Domain, perhaps reflecting a thicker lithosphere that delayed initiation of the Brasiliano Orogeny.In contrast with the igneous rock-zircon record, the detrital zircon record requires sources with ages that span almost the whole Proterozoic eon. The presence of zircons ages in the 1.5-1.0Ga and 0.85-0.65Ga intervals, which contrasts with their absence, in the first case, or rarity, in the second case, amongst the igneous rocks, may be explained by derivation from igneous sources as yet undiscovered or removed by erosion, and/or by provenance from distal sources. The occurrence of 2.15-2.05Ga-old detrital zircons in the Rio Grande do Norte Domain and of Tonian zircons in this domain and in the Ceará Central and Médio Coreaú domains imply the inexistence of physical barriers separating the northern and southern domains of the Borborema Province during the Neoproterozoic. The results are consistent with deposition in an intracratonic setting that became the site of lithospheric extension in response to far-field stresses. The ages of the youngest detrital zircons (650-630Ma) indicate that deposition ended just before or at the beginning of the Brasiliano Orogeny. © 2014 Elsevier Ltd.

Melo F.P.,Federal University of Pernambuco
Trends in ecology & evolution | Year: 2013

With the decreasing affordability of protecting large blocks of pristine tropical forests, ecologists have staked their hopes on the management of human-modified landscapes (HMLs) to conserve tropical biodiversity. Here, we examine key forces affecting the dynamics of HMLs, and propose a framework connecting human disturbances, land use, and prospects for both tropical biodiversity and ecosystem services. We question the forest transition as a worldwide source of new secondary forest; the role played by regenerating (secondary) forest for biodiversity conservation, and the resilience of HMLs. We then offer a conceptual model describing potential successional trajectories among four major landscape types (natural, conservation, functional, and degraded) and highlight the potential implications of our model in terms of research agendas and conservation planning. Copyright © 2013 Elsevier Ltd. All rights reserved.

Guerra M.,Federal University of Pernambuco
Plant Biosystems | Year: 2012

Detailed comparative karyotype analyses have proved to be an important tool for taxonomy and for understanding chromosome evolution. The basic principle of cytotaxonomy is that closely related species share a more similar karyotype than less related ones. However, phylogenetic studies have demonstrated that some karyotype features are more often recurrent than previously thought, meaning that similarity is not all. Two other criticisms to the cytotaxonomical interpretation are intraspecific variation, traditionally neglected, and the interpretation of chromosomal alterations based only on classical structural changes, without any investigative support. Chromosome numbers and nuclear DNA content are among the most reliable and practical characters for cytotaxonomical analyses involving a large number of species, whereas chromosome mapping with molecular probes is more recommended for a restricted number of species. In both cases, a robust phylogenetic tree is necessary to understand the relationships between species and their karyotype evolution. Evolutionary inferences based only on putative karyological trends are no longer sustainable. © 2012 Copyright Taylor and Francis Group, LLC.

Ivar Do Sul J.A.,Federal University of Pernambuco | Costa M.F.,Federal University of Pernambuco
Environmental Pollution | Year: 2014

Recently, research examining the occurrence of microplastics in the marine environment has substantially increased. Field and laboratory work regularly provide new evidence on the fate of microplastic debris. This debris has been observed within every marine habitat. In this study, at least 101 peer-reviewed papers investigating microplastic pollution were critically analysed (Supplementary material). Microplastics are commonly studied in relation to (1) plankton samples, (2) sandy and muddy sediments, (3) vertebrate and invertebrate ingestion, and (4) chemical pollutant interactions. All of the marine organism groups are at an eminent risk of interacting with microplastics according to the available literature. Dozens of works on other relevant issues (i.e., polymer decay at sea, new sampling and laboratory methods, emerging sources, externalities) were also analysed and discussed. This paper provides the first in-depth exploration of the effects of microplastics on the marine environment and biota. The number of scientific publications will increase in response to present and projected plastic uses and discard patterns. Therefore, new themes and important approaches for future work are proposed. © 2013 Elsevier Ltd. All rights reserved.

Agency: European Commission | Branch: FP7 | Program: CP-FP-SICA | Phase: SSH.2012.2.1-2 | Award Amount: 1.33M | Year: 2013

DESAFIO means challenge in both Portuguese and Spanish. The guiding concept of our proposal is to make a contribution towards tackling what is arguably one of the major challenges facing Brazil and Latin American countries in the 21st century: eradicating structural social inequality in the access to essential water and sanitation services. The overarching objective of our proposal is assessing existing experiences and developing new strategies that bring about sustainable, appropriate, and innovative socio-technical solutions to foster economic and social development through social transformation in vulnerable communities, particularly with reference to access to safe water supply and sanitation in urban, peri-urban, and rural areas of South America, with a particular emphasis on Brazil. These strategies will be developed through research and networking that actively engages beneficiary communities, practitioners, local authorities, and other relevant actors in their planning, design, assessment, implementation, monitoring, validation, and diffusion. Our transdisciplinary approach is predicated on a close interaction with non-academic actors in the production and validation of knowledge, among other things to underpin policy and behavioural transformations. We have selected a number of case studies that will cover a range of situations and characteristics, from informal settlements in the urban periphery of world megacities (Rio de Janeiro, Brazil) and in peri-urban areas of provincial capitals (Cali, Colombia), favelas located in the heart of booming mid-range urban centres (Recife, Brazil), to small rural villages (Mondomo, Colombia) and communities in semi-arid areas (Cear and Minas Gerais, Brazil and Santa Fe, Argentina). We will endeavour to draw lessons and develop recommendations that are applicable to other socio-cultural and economic contexts across the developing world.

The present invention provides fluorescent nanoparticle composites themselves, the process of preparing such composites, to systems for rapid diagnosis (as kits) containing such composites, and to the use of such composites. In a preferential embodiment, the composites of the present invention have an affinity for biological molecules, such as DNA. The present invention also comprises the preparation of probes containing biological material, upon which are added fluorescent nanoparticle composites, making viable a rapid and economic biological diagnosis of, for example, diseases and genetic traits, notably in the medical and veterinarian fields. There is yet the fact that the absorption of radiation in the ultraviolet and visible regions provides advantageous use of its fluorescent properties in photovoltaic or electroluminescent devices, such as organic LEDs, or for the increase in luminous gain of fluorescent lamps, which represents another characteristic of the invention.

Federal University of Pernambuco | Date: 2015-01-12

Disclosed is a process for retrieval of nucleotide sequence. The process includes mixing iron chloride tetrahydrate with iron (III) chloride hexahydrate in solution; adding ammonium hydroxide to the mixture and stirring to form maghemite nanoparticles; stirring the maghemite nanoparticles in a solution with an inorganic acid, a surfactant and a monomer precursor of a conducting polymer; initiating polymerization of the monomer by adding the inorganic acid and an oxidizing agent to the stirred solution and further stirring to yield Polyaniline/maghemite nanocomposites; adding the nanocomposites to an first aqueous solution of the nucleotide sequence and stirring so as to electrostatically interact the nanocomposites with the nucleotide sequence; and weakening the electrostatic interaction between the nanocomposite and the nucleotide sequence to recover the nanocomposite independently of the nucleotide sequence.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.3.3 | Award Amount: 8.15M | Year: 2011

The design of innovative products and services that take advantage of Systems of Systems (SoS) technology is in its infancy. It is hampered by the complexity caused by the heterogeneity and independence of SoS constituent systems and the difficulty of communication between diverse stakeholders. The state of the art in SoS engineering lacks models and tools that help developers to make trade-off decisions during design and evolution, and assist in working out and recording precise contracts between constituents and the global SoS. This leads to sub-optimal design and expensive rework during integration and in service.\nCOMPASS will augment existing industry tools and practice with an underlying modelling language in which SoS architectures and contracts can be expressed. A formal semantic foundation the first to be developed specifically for SoS engineering will enable this language to support analysis of global SoS properties. The language and methods will be supported by an open, extendible tools platform with integrated prototype plug-ins for model construction, dynamic analysis by simulation and test automation, static analysis by model-checking and proof, and links to an established architectural modelling language (SysML). These strengthened foundations and tools will support enhanced methods guidelines that help users embed this new technology in industrial SoS practice.\nTechnical advances in COMPASS are focussed on industry needs evaluated through substantial industry-led case studies in three diverse and complementary areas. These will be augmented by challenge problems solicited from a range of SoS stakeholders and developer organisations through a special interest group. The open platform, tools plug-ins, semantics, development guidelines, industry case study experience and challenge problems will ensure that COMPASSs outputs can be readily exploited by SoS developers and stakeholders as well as in future research and development.

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