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Mediouni M.,2500 Boul Of Luniversite | Volosnikov A.,Federal State Budgetary Institution
Journal of Orthopaedics | Year: 2015

Generally, in some universities of medicine, orthopaedic training procedures represent a difficult task due to the inadequacies of the systems, the resources, and the use of technologies. This article explains the challenges and the needs for more research in the issue of orthopaedic simulation around the world. © 2015 Prof. P K Surendran Memorial Education Foundation. Source

Federal State Budgetary Institution and Moscow State Technical University | Date: 2010-12-24

The invention pertains to the field of nuclear physics and can be used in system for identifying nuclear explosions based on the measured activities in the atmosphere of naturally-occurring radioactive gases (NORG). The technical result is an increase in the determination efficiency and in the reliability of punctual estimations of deposits from various types of fission in the global activity for each krypton and xenon isotope.

Sakhno N.G.,Federal State Budgetary Institution | Gunar O.V.,Federal State Budgetary Institution
Russian Journal of Biopharmaceuticals | Year: 2016

The article described the typed of cellular products, featured of its production and quality control. The data on microbial contaminants species, potential sources of contamination and ways to eliminate it are given. Particular attention is paid to rapid microbiological methods of sterility testing. The prospects of its development and implementation to cellular products sterility control are discussed. © 2016, Folium Ltd. All rights reserved. Source

Ershov F.I.,Federal State Budgetary Institution | Narovlyansky A.N.,Federal State Budgetary Institution
Voprosy Virusologii | Year: 2015

Domestic researchers succeeded to create a group of original Interferon inducers (II) with a high chemotherapeutic index and suitable for the prevention and treatment of viral infections and a number of other diseases. Clinical application of II concerns, first of all, a wide range of viral infections: influenza and other acute respiratory viral infections, herpes, hepatitis, encephalitis, rabies, slow and mixed infections, etc. The accumulated experience is generalized and the conclusion is made about the main advantages of II, which induce a balanced synthesis of endogenous interferon without antigenicity of its own. It is emphasized that a single injection of II "includes" synthesis of IFN in certain populations of ceils and organs and provides a relatively long circulation of IFN at a therapeutic level and creation of long-term anti-virus resistance. It Is concluded that, in general, interferon inducers with pronounced antiviral and immunomodulatory properties are currently used as effective tools for the prevention and treatment of a variety of diseases. The fact that II different in their chemical nature act at different stages of reproduction of viruses and affect various links of the innate and adaptive immunity explains the increased scope of the application of this group of drugs in medical practice. Source

Karetnikova V.,Kemerovo State Medical Academy | Gruzdeva O.,Federal State Budgetary Institution | Uchasova E.,Federal State Budgetary Institution | Osokina A.,Kemerovo State Medical Academy | Barbarash O.,Kemerovo State Medical Academy
BMC Endocrine Disorders | Year: 2016

Background: Patients with myocardial infarction (MI) have a high mortality. Therefore, new risk markers and predictors of an adverse outcome for MI are required. The role of hyperglycemia in the development of cardiovascular complications in MI patients is still unclear. Methods: A total of 529 consecutive patients with the diagnosis of ST-segment elevation acute coronary syndrome within 24 h of the onset of symptoms were included in the study. All of the patients underwent blood glucose measurement at admission to hospital. The glycemic profile, including measurement of blood glucose levels early in the night and in the morning (3 a.m. and 5 a.m.), was assessed in 77 patients with diabetes on days 6-10 of the course of MI to monitor the efficiency of blood glucose-lowering therapy and to detect hypoglycemic episodes. Results: In-hospital mortality showed relationship between the level of blood glucose on admission and in-hospital mortality in patients with MI with ST-segment elevation in combination with diabetes mellitus. There was a direct linear relationship between blood glucose levels and in-hospital mortality in patients without diabetes. Conclusion: Episodes of hypoglycemia recorded in MI patients with diabetes in the hospital stage of treatment do not determine the prognosis, but enable identification of patients with an unfavorable course in the postinfarction period. © 2016 Karetnikova et al. Source

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