Federal Medical Biophysical Center

Moscow, Russia

Federal Medical Biophysical Center

Moscow, Russia

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PubMed | Federal Medical Biophysical Center, Ukrainian Academy of Sciences, University of Milan Bicocca, Robert Wood Johnson Medical Center and 10 more.
Type: Journal Article | Journal: BMC public health | Year: 2017

The disasters at Seveso, Three Mile Island, Bhopal, Chernobyl, the World Trade Center (WTC) and Fukushima had historic health and economic sequelae for large populations of workers, responders and community members.Comparative data from these events were collected to derive indications for future preparedness. Information from the primary sources and a literature review addressed: i) exposure assessment; ii) exposed populations; iii) health surveillance; iv) follow-up and research outputs; v) observed physical and mental health effects; vi) treatment and benefits; and vii) outreach activities.Exposure assessment was conducted in Seveso, Chernobyl and Fukushima, although none benefited from a timely or systematic strategy, yielding immediate and sequential measurements after the disaster. Identification of exposed subjects was overall underestimated. Health surveillance, treatment and follow-up research were implemented in Seveso, Chernobyl, Fukushima, and at the WTC, mostly focusing on the workers and responders, and to a lesser extent on residents. Exposure-related physical and mental health consequences were identified, indicating the need for a long-term health care of the affected populations. Fukushima has generated the largest scientific output so far, followed by the WTCHP and Chernobyl. Benefits programs and active outreach figured prominently in only the WTC Health Program. The analysis of these programs yielded the following lessons: 1) Know who was there; 2) Have public health input to the disaster response; 3) Collect health and needs data rapidly; 4) Take care of the affected; 5) Emergency preparedness; 6) Data driven, needs assessment, advocacy.Given the long-lasting health consequences of natural and man-made disasters, health surveillance and treatment programs are critical for management of health conditions, and emergency preparedness plans are needed to prevent or minimize the impact of future threats.


Grigoriev Y.,Federal Medical Biophysical Center
Environmentalist | Year: 2012

Today world population lives in a new electromagnetic environment, characterized with (i) around the clock enforcement of chronic exposure of all age and gender groups to a wide range of modulated electromagnetic fields (EMF) from base stations; (ii) daily, repeated from early childhood throughout entire life exposure to EMF RF mobile phone the brain and vestibular receptor apparatus and auditory analyzers, located directly "under the EMF beam" in the inner ear. On the other hand, the world science and epidemiology is missing well-planned and executed research results of prolonged exposure of EMF RF on the brain. International recommendations and domestic guidelines do not include changing conditions of RF EMF on the population: the brain has become a critical organ, and the children entered the risk group. The population continues to actively use the mobile phone. In this situation the problem of assessing the risk of mobile communications has become a social and ethical. © 2011 Springer Science+Business Media, LLC.


Kyzlasov P.S.,Federal Medical Biophysical Center | Voskanyan S.E.,Federal Medical Biophysical Center | Paklina O.V.,Federal Medical Biophysical Center
Cellular Transplantation and Tissue Engineering | Year: 2013

The paper presents results of an experimental study on the efficiency of cationic surfactant for the prevention of adhesion formation after intraperitoneal operations. According to the literature of the world the incidence of abdominal adhesive disease has a significant downward trend, due to the lack of adequate preventive measure and determine the need for new tools have protivospaechnym action. The studies were conducted on 60 Wistar rats. In the study group was modeled adhesive disease of the abdominal cavity, then before suturing wounds laporatomnoy performed abdominal introduction proverhnostno-active substance, «Miramistin». According to the histological study in a group of animals, which was administered prophylactically Miramistin, there were statistically significant χ2 criterion examined Yatescorrected for the frequency of adhesions and reduced the severity of adhesions. © Human stem cells institute, 2013.


Grigoriev Y.G.,Federal Medical Biophysical Center | Grigoriev O.A.,Federal Medical Biophysical Center | Ivanov A.A.,Federal Medical Biophysical Center | Lyaginskaya A.M.,Federal Medical Biophysical Center | And 7 more authors.
Bioelectromagnetics | Year: 2010

This paper presents the results of a replication study performed to investigate earlier Soviet studies conducted between 1974 and 1991 that showed immunological and reproductive effects of long-term low-level exposure of rats to radiofrequency (RF) electromagnetic fields. The early studies were used, in part, for developing exposure standards for the USSR population and thus it was necessary to confirm the Russian findings. In the present study, the conditions of RF exposure were made as similar as possible to those in the earlier experiments: Wistar rats were exposed in the far field to 2450 MHz continuous wave RF fields with an incident power density in the cages of 5 W/m2 for 7 h/day, 5 days/week for a total of 30 days, resulting in a whole-body SAR of 0.16 W/kg. Effects of the exposure on immunological parameters in the brain and liver of rats were evaluated using the complement fixation test (CFT), as in the original studies, and an additional test, the more modern ELISA test. Our results, using CFT and ELISA, partly confirmed the findings of the early studies and indicated possible effects from non-thermal RF exposure on autoimmune processes. The RF exposure resulted in minor increases in formation of antibodies in brain tissue extract and the exposure did not appear to be pathological. In addition, a study was conducted to replicate a previous Soviet study on effects from the injection of blood serum from RF-exposed rats on pregnancy and foetal and offspring development of rats, using a similar animal model and protocol. Our results showed the same general trends as the earlier study, suggesting possible adverse effects of the blood serum from exposed rats on pregnancy and foetal development of intact rats, however, application of these results in developing exposure standards is limited. Copyright © 2010 Wiley-Liss, Inc.


PubMed | Federal Medical Biophysical Center
Type: Journal Article | Journal: Bioelectromagnetics | Year: 2010

This paper presents the results of a replication study performed to investigate earlier Soviet studies conducted between 1974 and 1991 that showed immunological and reproductive effects of long-term low-level exposure of rats to radiofrequency (RF) electromagnetic fields. The early studies were used, in part, for developing exposure standards for the USSR population and thus it was necessary to confirm the Russian findings. In the present study, the conditions of RF exposure were made as similar as possible to those in the earlier experiments: Wistar rats were exposed in the far field to 2450 MHz continuous wave RF fields with an incident power density in the cages of 5 W/m for 7 h/day, 5 days/week for a total of 30 days, resulting in a whole-body SAR of 0.16 W/kg. Effects of the exposure on immunological parameters in the brain and liver of rats were evaluated using the complement fixation test (CFT), as in the original studies, and an additional test, the more modern ELISA test. Our results, using CFT and ELISA, partly confirmed the findings of the early studies and indicated possible effects from non-thermal RF exposure on autoimmune processes. The RF exposure resulted in minor increases in formation of antibodies in brain tissue extract and the exposure did not appear to be pathological. In addition, a study was conducted to replicate a previous Soviet study on effects from the injection of blood serum from RF-exposed rats on pregnancy and foetal and offspring development of rats, using a similar animal model and protocol. Our results showed the same general trends as the earlier study, suggesting possible adverse effects of the blood serum from exposed rats on pregnancy and foetal development of intact rats, however, application of these results in developing exposure standards is limited.

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