Sickle cell disease: From molecular aspects to clinical practice. A case report and a literature analysis [Dŕpanocytose : Des aspects moĺculaires à la pratique clinique. À propos dun cas et revue de la litt́rature]
Huynh-Moynot S.,Fdration dAnesthsie ranimation et des Urgences |
Moynot J.-C.,Fdration de Chirurgie |
Commandeur D.,Fdration dAnesthsie ranimation et des Urgences |
Des Deserts M.D.,Fdration dAnesthsie ranimation et des Urgences |
And 3 more authors.
Annales de Biologie Clinique | Year: 2011
Sickle cell disease is the genetic disease most frequently detected at birth in France. The comprehension and knowledge of its pathophysiology allow to establish the principles of management for the drepanocytic patient, especially in the perioperative phase. In the light of recent recommendations published for anesthesia of a drepanocytic adult, this clinical case revealed allows to reexamine that subject, with a focus on biological aspects, which are transfusional strategy and antibioprophylaxy. The presented observation is a concrete feature of daily collaboration between clinician and biologist, which is an essential point of the ISO standard EN 15189 concerning laboratories' accreditation.