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La Jolla, CA, United States

Patent
Fate Therapeutics | Date: 2013-02-22

The invention is directed, in part, to compositions comprising small molecule compounds to treat or prevent hearing loss. Compositions of the present invention also promote sensory hair cell regeneration. Particular compositions comprise ellipticine derivatives, and optionally one or more small molecules that increase Atoh1 expression or activity, and optionally one or more growth factors.


Patent
Fate Therapeutics | Date: 2012-01-11

The invention provides novel Wnt polypeptides that have enhanced solubility and improved biologic drug-like properties, and polynucleotides encoding the Wnt polypeptides of the invention. The Wnt polypeptides of the invention can be used therapeutically, such as, for example, in methods of preventing or treating muscle loss and/or promoting muscle hypertrophy and growth.


Patent
Fate Therapeutics | Date: 2013-06-27

Provided are improved vessels for cell culture, cell storage, treatment of cells, and cell therapy. The improved vessels comprise one or more devices temperature indicating devices, elapsed time indicating devices and/or devices that indicate environmental conditions of the vessel contents, such as pH, oxygen and carbon dioxide concentration, and glucose concentration.


Patent
Fate Therapeutics | Date: 2014-09-05

The invention is directed, in part, to compounds of structure (I) to treat or prevent hearing loss. Compounds of the present invention also promote sensory hair cell regeneration. Particular compositions comprise compounds of structure (I), and optionally one or more small molecules that increase the proliferation of supporting cells.


Patent
Fate Therapeutics | Date: 2012-11-29

The invention provides compositions comprising stem and/or progenitor cells that have been treated to enhance the therapeutic properties of the cells for treating ischemia. In particular, the present invention relates to the use of stem and/or progenitor cells having enhanced therapeutic properties to treat an ischemic tissue, a tissue damaged by ischemia, or at least one symptom associated with an ischemic tissue or a tissue damaged by ischemia.

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