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Sandu N.,University Paris - Sud | Sadr-Eshkevari P.,Farzan Clinical Research Institute | Schaller B.J.,University Paris - Sud
Journal of Medical Case Reports | Year: 2011

We describe the discovery of the trigemino-cardiac reflex by Schaller in 1999 and the continued improvement of the knowledge about the trigemino-cardiac reflex involved in neurosurgery, especially in skull base surgery, during the past several years. The achieved medical progress could be gained only by the practical experience described by different case reports and later case series that have been published in several principal scientific journals. Additionally, we explain the scientific as well as clinical importance of the communication of the case reports on TCR. Special reference has been given to the validity of the case reports for new phenomena in clinical medicine. © 2011 Sandu et al; licensee BioMed Central Ltd. Source


Shariati A.,Ahvaz Jundishapur University of Medical Sciences | Jahani S.,Ahvaz Jundishapur University of Medical Sciences | Hooshmand M.,Ahvaz Jundishapur University of Medical Sciences | Khalili N.,Farzan Clinical Research Institute
Complementary Therapies in Medicine | Year: 2012

Objective: Our purpose was to investigate the effects of acupressure on sleep quality in hemodialysis patients. Design: Randomized clinical trial. Setting: The setting of the study was dialysis wards located in two university hospitals (Imam and Golestan) in Ahvaz, Iran. Interventions: 48 end-stage renal disease patients on hemodialysis who scored 5 points or higher on the Pittsburgh Sleep Quality Index (PSQI) were enrolled to the study. Acupressure group received acupressure intervention on the Shenmen (He7) and He Gu (Li4) points in the hands and Sanyingjao (sp6) point in the feet for 4 weeks beside routine care and control group received only routine care. Main outcome measures: subjective sleep quality, latency and duration, habitual sleep efficiency; sleep disturbances, daytime functional status, and use of sleeping medications. Results: The result indicated significant differences between the acupressure group and the control group after intervention in PSQI global scores (p<0.001) and all sleep quality indices between two groups after intervention: subjective sleep quality (p<0.001), sleep latency (p<0.001), sleep duration (p<0.001), sleep efficiency (p=0.006), sleep disturbance (p<0.001), the use of sleeping medication (p=0.028), and daytime dysfunction (p<0.001). Conclusion: This study supports the effectiveness of acupressure in improving sleep quality of end-stage renal disease patients as a noninvasive therapy. © 2012 Elsevier Ltd. Source


Faraji F.,Arak University of Medical Sciences | Zarinfar N.,Arak University of Medical Sciences | Zanjani A.T.,Islamic Azad University of Arak | Morteza A.,Farzan Clinical Research Institute
Pain Physician | Year: 2012

Background: Recent studies have shown a positive correlation between Helicobacter pylori (H. pylori)infection and migraine headache. Objective: To study the impact of H. pylori eradication on migraine headache. Study Design: Double blind, randomized, controlled clinical trial. Setting: Sixty-four patients diagnosed with migraine-type headache were included in the study. The patients were randomly allocated into 2 groups: a treatment group that received migraine treatment and H.pylori eradication treatment, and a control group that received migraine treatment and a placebo in place of H. pylori eradication treatment. Methods: There were 25 women and 7 men in the treatment group and 22 women and 10 men in the control group. The MIDAS (Migraine Disability Assessment) questionnaire was used to assess the severity of symptoms, before and after treatment. Result: There was no significant difference between treatment group patients and control group patients with respect to age (44.6 ± 8.8 vs. 43.8 ± 13.8), clinical symptoms and signs. In the beginning of the study, patients in the treatment group had a higher MIDAS compared to patients in the control group (28.87 ± 6.18 vs. 25.43 ± 7.13, P < 0.05). There was no significant difference between the treatment and control groups, with respect to the MIDAS, after treatment (20.09 ± 1.14 vs. 20.00 ± 1.150, P = 0.5). General linear model, repeated measures demonstrated that the reduction in the MIDAS score was more prominent in the treatment group (Mean Square 164.25, F: 2.02, P = 0.05). Limitations: Short-term follow up. Conclusion: H. pylori eradication may have a beneficial role on migraine headache. This shows the significance of H. pylori treatment in the management of migraine headache among Iranian patients. Source


Fallahi Khoshknab M.,University of Social Welfare and Rehabilitation Sciences | Sheikhona M.,Razi Psychiatric Center | Rahgozar M.,University of Social Welfare and Rehabilitation Sciences | Sodagari F.,Farzan Clinical Research Institute
Journal of Psychiatric and Mental Health Nursing | Year: 2014

This study was aimed at assessing the impact of group psychoeducation therapy on family burden in caregivers of Iranian patients with schizophrenia during the acute phase of the disease. Using a randomized-controlled trial design, 71 caregivers of patients with schizophrenia were randomly assigned to either a 4-week group psychoeducational programme (n = 36) or the control group (n = 35). Family burden was assessed by Family Burden Index Schedule (FBIS) at the beginning, and after a month of psychoeducation therapy as a follow-up. FBIS assesses family burden in six different dimensions with score ranging from 0 to 48, higher scores indicating higher burdens. At baseline mean, FBIS score was not significantly different between the cases and the controls. After the intervention, the mean total FBIS score was significantly lower in the case group compared with the control group (P < 0.001). In the intervention group, FBIS score change was significant through the study in all dimensions as well as the total score (P < 0.001). A significant reduction in family burden has been achieved by implementing group psychoeducational programmes for inpatients with acute phase schizophrenia in Iranian population. © 2013 John Wiley & Sons Ltd. Source


Sharifi A.,Kerman Medical University | Sharifi L.,Kerman Medical University | Morteza A.,Farzan Clinical Research Institute
International Ophthalmology | Year: 2012

Here we aimed to define keratometric and refractive astigmatism in a series of patients who underwent phacoemulsification, using small corneal incision and implantation of foldable intraocular lenses. Furthermore, we compared keratometric astigmatism and refractive astigmatism of the patients both before and after surgery. We performed a follow-up study of patients with newly diagnosed cataract before and after phacoemulsification surgery. Eighty eyes from 78 patients with a mean age of 62.9 ± 12.03 (32-86) years were studied. Thirty-nine (48.8 %) were male and 41(51.2 %) were female. All subjects underwent 3.5 mm corneal incision with the temporal (75 patients; 94 %) or superior (5 patients; 6 %) approach. The patients were followed for a mean of 74.21 ± 71.25 (30-400) days. Patients had higher values of keratometric measurements after surgery compared to those before surgery [45.81 ± 0.11 (45.06-45.94) vs. 45.2 ± 0.20 (44.6-45.41)] (p < 0.001). There was no significant difference in the keratometric astigmatism, refractive astigmatism and keratometry axis pre- and postoperatively. The mean keratometric astigmatism was 0.9 ± 0.54 (0.00-4.00) diopters (D) preoperatively and 0.93 ± 0.45 (0.00-4.00) D postoperatively (p = 0.444). The keratometric axis was 97.7 ± 9.4 preoperatively and 115 ± 15.8 postoperatively (p = 0.185). Refractive astigmatism was 1.15 ± 0.77 (5-180) with the refractive axis of 89.7 ± 5.89 (5-180) degrees in the follow-up (p = 0.752). Ninety percent of the patients had <1.00 D difference in the keratometric and refractive astigmatism, postoperatively. In conclusion while there is no significant difference in postoperative keratometric and refractive astigmatism in most of the eyes, about 10 % show >1 D difference in these measurements. © 2012 Springer Science+Business Media B.V. Source

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