Middlebury, VT, United States
Middlebury, VT, United States
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PubMed | Royal Womens Hospital, Faraday Inc., Michael Murphy Research, University of Melbourne and Cancer Council Victoria
Type: Journal Article | Journal: Sexual health | Year: 2016

Background The study evaluated acceptability, invitation letters and the test kit for a trial of human papillomavirus (HPV) self-sampling among never- and under-screened women in Australia.Victorian women, 30-69 years, who had never had a Pap test or were overdue for one, participated. Four focus groups including eight to nine participants segmented by age (30-49 and 50-69 years) and screening history (never- and under-screened) were conducted in August 2013. Discussions were recorded and transcribed verbatim and data analysed using thematic content analysis.The response to the concept of HPV self-sampling was positive. Decision-making was largely influenced by the content of a pre-invitation letter. Appealing features of self-sampling were cost (free), convenience (home-based) and anticipated less discomfort (with a swab) than a Pap test. Small kits that fit in mailboxes were preferred over post office parcel collection. The perceived barriers include concerns about test accuracy and lack of confidence that a home-based test would give the same results as a physician administered test. Women wanted information on the timing of receipt of the results and information about the organisation providing the test.HPV self-sampling is a possible alternative for Australian women who are reluctant to have a Pap test and may increase the likelihood of participation in cervical cancer screening if womens concerns about it can be addressed. The findings of this study are relevant for researchers, policymakers and practitioners implementing self-sampling for under-screened women as part of cervical screening programs.

Gracia-Fernandez C.,Faraday Inc. | Tarrio-Saavedra J.,University of La Coruña | Lopez-Beceiro J.,University of La Coruña | Gomez-Barreiro S.,University College Dublin | And 2 more authors.
Journal of Thermal Analysis and Calorimetry | Year: 2011

The use of pressure cell attached to a temperature modulated differential scanning calorimeter (TMDSC) is investigated to perform modulated DSC experiments at high pressures (TMPDSC). No previous reports were found on the use of TMPDSC. In this study, the proposed method is applied to the study of the pressure effect on the curing reaction of an epoxy system. Curing quasi-isothermal modulated experiments were performed at different pressures to evaluate the vitrification time. Linear heating modulated tests were also successfully performed at different pressures to separate the reversing glass transition effect from the residual exothermic cure reaction. The curing enthalpy, conversion versus temperature, and glass transition of the fully cured thermoset were also evaluated. All the studied parameters resulted to be affected by the pressure in the range from atmospheric pressure to 35 bar. It was observed that the curing enthalpy, the reaction rate and the conversion at any given time increase with any pressure increment. The usefulness of TMDSC to characterize the curing of thermosets is extended by PTMDSC to situations, i.e., aeronautics industry, where pressure curing is needed. © 2011 Akadémiai Kiadó, Budapest, Hungary.

Gracia-Fernandez C.A.,Faraday Inc. | Gomez-Barreiro S.,University College Dublin | Lopez-Beceiro J.,University of La Coruña | Tarrio Saavedra J.,University of La Coruña | And 2 more authors.
Polymer Testing | Year: 2010

Measurements of the glass transition temperature obtained by dynamic mechanical analysis (DMA) and temperature modulated differential scanning calorimetry (TMDSC) are reported to be different. This was mainly attributed to the frequency effect. To obtain comparable measurements, experimental conditions were studied. Although some experimental issues had to be fixed, it was possible to apply the same frequency and temperature using quasi-isothermal conditions in both instruments. The method was tested with three different polymer samples. It was then found that when choosing a suitable response parameter, i.e. the phase angle, the dynamic glass transition temperature values obtained by both methods are practically the same. © 2010 Elsevier Ltd. All rights reserved.

Gertig D.M.,Faraday Inc. | Gertig D.M.,University of Melbourne | Brotherton J.M.L.,Faraday Inc. | Brotherton J.M.L.,University of Melbourne | And 4 more authors.
BMC Medicine | Year: 2013

Background: Australia was one of the first countries to introduce a publicly funded national human papillomavirus (HPV) vaccination program that commenced in April 2007, using the quadrivalent HPV vaccine targeting 12- to 13-year-old girls on an ongoing basis. Two-year catch-up programs were offered to 14- to 17- year-old girls in schools and 18- to 26-year-old women in community-based settings. We present data from the school-based program on population-level vaccine effectiveness against cervical abnormalities in Victoria, Australia.Methods: Data for women age-eligible for the HPV vaccination program were linked between the Victorian Cervical Cytology Registry and the National HPV Vaccination Program Register to create a cohort of screening women who were either vaccinated or unvaccinated. Entry into the cohort was 1 April 2007 or at first Pap test for women not already screening. Vaccine effectiveness (VE) and hazard ratios (HR) for cervical abnormalities by vaccination status between 1 April 2007 and 31 December 2011 were calculated using proportional hazards regression.Results: The study included 14,085 unvaccinated and 24,871 vaccinated women attending screening who were eligible for vaccination at school, 85.0% of whom had received three doses. Detection rates of histologically confirmed high-grade (HG) cervical abnormalities and high-grade cytology (HGC) were significantly lower for vaccinated women (any dose) (HG 4.8 per 1,000 person-years, HGC 11.9 per 1,000 person-years) compared with unvaccinated women (HG 6.4 per 1,000 person-years, HGC 15.3 per 1,000 person-years) HR 0.72 (95% CI 0.58 to 0.91) and HR 0.75 (95% CI 0.65 to 0.87), respectively. The HR for low-grade (LG) cytological abnormalities was 0.76 (95% CI 0.72 to 0.80). VE adjusted a priori for age at first screening, socioeconomic status and remoteness index, for women who were completely vaccinated, was greatest for CIN3+/AIS at 47.5% (95% CI 22.7 to 64.4) and 36.4% (95% CI 9.8 to 55.1) for women who received any dose of vaccine, and was negatively associated with age. For women who received only one or two doses of vaccine, HRs for HG histology were not significantly different from 1.0, although the number of outcomes was small.Conclusion: A population-based HPV vaccination program in schools significantly reduced cervical abnormalities for vaccinated women within five years of implementation, with the greatest vaccine effectiveness observed for the youngest women. © 2013 Gertig et al.; licensee BioMed Central Ltd.

Faraday Inc. | Date: 2012-08-31


Faraday Inc. | Date: 2016-02-08

Electric bicycles.

Faraday Inc. | Date: 2012-06-21

bicycles and electric bicycles.

Faraday Inc. | Date: 2013-04-01

An electric bicycle and electric bicycle frame including batteries or a battery pack stored in one or more tubes of the frame. In some cases, a pair of top tubes extend rearward of the bicycle seat tube, and an electronics housing may be disposed between the rearward extending top tube portions. Alternatively or in addition, a removable bottom bracket shell portion and a removable bottom bracket insert may be provided, to allow convenient access to the interior portions of the down tube and/or seat tube of the frame. A battery pack and/or a battery electronics management unit may be conveniently within one or both of the down tube and the seat tube.

Faraday Inc. | Date: 2012-09-24

An electric bicycle and electric bicycle frame including batteries stored in a pair of substantially parallel top tubes. In some cases, the top tubes extend rearward of the bicycle seat tube, and an electronics housing may be disposed between the rearward extending top tube portions.

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