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Geva S.,University of Cambridge | Bennett S.,Adolescent and Family Unit | Warburton E.A.,University of Cambridge | Patterson K.,MRC Cognition and Brain science Unit
Aphasiology | Year: 2011

Background: Patients with aphasia often complain that there is a poor correlation between the words they think (inner speech) and the words they say (overt speech). Aims: This study tried to characterise the relation between inner speech and overt speech in post-stroke aphasia. Methods & Procedures: We tested language abilities, speech apraxia, and performance on inner speech tasks, including homophone and rhyme judgements, of 27 patients with chronic post-stroke aphasia. Outcomes & Results: The patients with aphasia were distributed across the entire spectrum of abilities related to both inner and overt speech. For most patients, performance levels of inner and overt speech were similar. However, some patients had relatively better-preserved inner speech with a marked deficit in overt speech, while in others the opposite pattern was observed. Conclusions: The results are discussed within the framework of current models of language, and their implications for language therapy and aphasia diagnosis are outlined. © 2010 Psychology Press.


Wright B.,Adolescent and Family Unit | Beverley D.,York Hospital
Clinical Child Psychology and Psychiatry | Year: 2012

We report here on a case of severe pervasive refusal syndrome. This is of interest for three reasons. Firstly, most reported cases are adolescent girls; our case is regarding an adolescent boy. Secondly, he was successfully treated at home and thirdly, the serology showed an apparent infective pre-cursor to the illness with evidence of possible autoimmune serology.A 14-year old boy deteriorated from a picture where diagnosed CFS/ME developed into Pervasive Refusal Syndrome. This included the inability to move or speak, with closed eyes, multiple tics, facial grimacing, heightened sensitivity to noise (hyperacusis) and touch (hyperaesthesia), and inability or unwillingness to eat anything except small amounts of sloppy food. Successful rehabilitation is reported.Finally the issue of nomenclature is discussed, raising the question whether Pervasive Refusal Syndrome would be better renamed in a way that does not imply that the condition is always volitional and oppositional, as this can distract focus away from an alliance between family and clinicians. © 2011 The Author(s).


Whitaker S.,University of Huddersfield | Gordon S.,Adolescent and Family Unit
British Journal of Developmental Disabilities | Year: 2012

Seventeen 16-year-olds in special education were given both the Wechsler Adult Intelligence Scale (WAIS)-III and the Wechsler Intelligence Scale for Children (WISC)-IV in counterbalanced order. It was found that there was a significant floor effect on the WISC-IV due to low raw scores and raw scores of 0 being given a scaled score of 1. Extrapolating the relationship between raw scores and scaled scores down below raw score, one showed that the WISC-IV may be overestimating some low intelligence quotients (IQs) by several IQ point due to this floor effect. © The British Society of Developmental Disabilities 2012.


Tindall L.,Adolescent and Family Unit | Varley D.,Adolescent and Family Unit | Wright B.,Adolescent and Family Unit
Mental Health Review Journal | Year: 2016

Purpose - The purpose of this paper is to focus upon the challenges faced by a research team when conducting a computerised cognitive behaviour therapy (CCBT) trial for adolescents with low mood/ depression and how solutions were sought to eliminate these difficulties in future child and adolescent mental health clinical research. Design/methodology/approach - The authors have presented a number of problems faced by the research team when conducting a randomised controlled trial (RCT) concerning adolescents with low mood/depression. Findings - From examining the problems faced by the research team, the authors have provided key pieces of advice for prospective adolescent mental health RCTs. This advice includes developing clear project plans, setting strategies to encourage and maintain study information in the community and support recruitment, and keeping your organisation appraised of study needs and network and involve governance departments, IT and finance departments in these discussions early. Originality/value - RCTs, particularly those focusing on child and adolescent mental health, can face a number of difficulties throughout its stages of completion (from protocol development to follow-up analysis). Studies involving the use of technologies add a layer of complexity to this. This review will be of value to researchers aiming to run a high-quality RCT concerning child and adolescent mental health. © Emerald Group Publishing Limited.


PubMed | Adolescent and Family Unit
Type: Journal Article | Journal: Journal of autism and developmental disorders | Year: 2011

Twenty-two children with autism spectrum disorders who had not responded to supported behaviour management strategies for severe dysomnias entered a double blind, randomised, controlled crossover trial involving 3 months of placebo versus 3 months of melatonin to a maximum dose of 10 mg. 17 children completed the study. There were no significant differences between sleep variables at baseline. Melatonin significantly improved sleep latency (by an average of 47 min) and total sleep (by an average of 52 min) compared to placebo, but not number of night wakenings. The side effect profile was low and not significantly different between the two arms.

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