Billerica, MA, United States
Billerica, MA, United States

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An apparatus, method and products thereof provide an accelerated neutral beam derived from an accelerated gas cluster ion beam for processing materials.


An apparatus, method and products thereof provide an accelerated neutral beam derived from an accelerated gas cluster ion beam for processing materials.


A bone implantable medical device made from a biocompatible material, preferably comprising titanic or zirconia, has at least a portion of its surface modified to facilitate improved integration with bone. The implantable device may incorporate a surface infused with osteoinductive agent and/or may incorporate holes loaded with a therapeutic agent. The infused surface and/or the holes may be patterned to determine the distribution of and amount of osteoinductive agent and/or therapeutic agent incorporated. The rate of release or elution profile of the therapeutic agent may be controlled. Methods for producing such a bone implantable medical device are also disclosed and employ the use of ion beam irradiation, preferably gas cluster ion beam irradiation for improving bone integration.


A method of modifying a surface of implantable medical device provides coating at least a first portion of the surface of the medical device with a therapeutic agent to form a coated surface region; and irradiating at least a portion of the coated surface region with a gas cluster ion beam infusing the therapeutic agent into the at least a portion of the coated surface region.


Patent
Exogenesis | Date: 2014-05-21

A film and method of forming a film provides an unmodified starting layer of a starting material, the starting layer having opposed first and second surfaces and an initial thickness, T_(1), and a modified surface layer of thickness T_(2 )which is less than T_(1), formed in at least a portion of the second surface, wherein a portion of the modified surface layer is not supported by unmodified starting material removed from the first surface opposite the modified surface layer.


A method of improving the surface of an object treats the surface with a neutral beam formed from a gas cluster ion mean to create a surface texture and/or increase surface area.


Patent
Exogenesis | Date: 2014-02-04

An apparatus and method for producing a deflection of a Neutral Beam derived from a gas-cluster ion-beam deflects the gas-cluster ion-beam prior to dissociation of gas clusters and removal of tons.


Patent
Exogenesis | Date: 2015-12-31

In one embodiment, a drug delivery system and method provide a member including a combination of a drug substance and a polymer or other material, and an encapsulating layer formed in an outer surface of the member by gas cluster ion beam irradiation of the outer surface of the member, which encapsulating layer is adapted to determine one or more characteristics of the drug delivery system.


Patent
Exogenesis | Date: 2015-11-16

The present disclosure describes methods, systems, and program products for generating an enhanced database, such as a geospatial database, and for searching an enhanced database, such as a geospatial database. The disclosed methods, systems, and program products incorporate a process for assigning labels to objects, such as polygons, linestrings, and points, based on the relationship between such polygons, linestrings, and points.


A method for treating a silicon substrate, and a silicon substrate, provide a surface treated with an accelerated neutral beam.

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