Midey A.J.,Excelllms Corporation |
Krueger C.A.,Excelllms Corporation |
Osgood M.A.,Excelllms Corporation |
Wu J.,Excelllms Corporation |
Wu C.,Excelllms Corporation
American Laboratory | Year: 2013
Electrospray-ionization High performance ion mobility spectrometry (ESI-HPIMS) is a sensitive and selective method for analyzing compounds relevant to current food safety priorities. HPIMS has two key components, a source for introducing and ionizing samples and the HPIMS analyzer for separating them. The instrument operates at atmospheric pressure, eliminating vacuum pumps needed for low pressures, and uses air as the mobility drift medium. The ions from the ESI source have desolvation region prior to injection into the drift region using a Bradbury-Nielsen gate. After the mobility based separation in the drift region, the ions are detected at a Faraday plate detector. HPIMS supports advances in ion mobility instrument construction to provide the speed and simplicity of IMS with figures-of-merit comparable to high-performance and ultra-high-performance liquid chromatography methods used in food screening.