Euroscreen SA

Gosselies, Belgium

Euroscreen SA

Gosselies, Belgium
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Patent
Novartis and Euroscreen S.A. | Date: 2014-10-23

The present invention relates to modulators of the interaction between G-protein coupled receptor 15(GPR15) and c10orf99. The modulator maybe a small chemical molecule, antibody or other therapeutic protein. Methods of medical treatment and methods of identifying modulators are also described.


Compounds of formula I are useful in treating and/or preventing inflammatory diseases.


The present invention relates to novel compounds of Formula I and their use in therapeutic treatments. The invention further relates to a novel chiral synthesis of 5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines using N-sp3 protective groups. The invention also provides intermediates for use in the synthesis of compounds of Formula I.


The present invention is directed to novel compounds of formula I and their use as therapeutic compounds.


Novel compounds of Formula I and their use in therapeutic treatments.


The present invention is directed to novel compounds of formula I and their use as therapeutic compounds.

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