European Center for Knee Research

Leuven, Belgium

European Center for Knee Research

Leuven, Belgium
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Soenen M.,Polyclinique du Parc | Soenen M.,Lille University Hospital Center | Baracchi M.,University of Florence | De Corte R.,European Center for Knee Research | And 3 more authors.
Journal of Arthroplasty | Year: 2013

When a stemmed TKA is needed in a femur in which a THA is already present, choosing an appropriate length for the TKA stem is crucial. Many surgeons intuitively fear that the distance between the stem tips correlates with the femur risk for fracture (RF). However, to date, no biomechanical data to support this intuition are available. Therefore, in this study, the RF in such a configuration was determined and compared for several activities, using a finite element modeling technique. During gait and sideways falling no difference in RF among different stem lengths was shown. However, a clear threshold appears during four-point bending. Stem tip distances shorter than 110. mm dramatically increased RF and, in osteoporotic bone, will certainly lead to fracture (RF. >. 1) and thus should be avoided. © 2013 Elsevier Inc.

Catani F.,Rizzoli Orthopaedic Institute | Innocenti B.,European Center for Knee Research | Belvedere C.,Rizzoli Orthopaedic Institute | Labey L.,European Center for Knee Research | And 2 more authors.
Clinical Orthopaedics and Related Research | Year: 2010

In vivo fluoroscopy is a well-known technique to analyze joint kinematics of the replaced knee. With this method, however, the contact areas between femoral and tibial components, fundamental for monitoring wear and validating design concepts, are hard to identify. We developed and tested a novel technique to assess condylar and post-cam contacts in TKA. The technique uses in vivo motion data of the replaced knee from standard fluoroscopy as input for finite element models of the prosthesis components. In these models, tibiofemoral contact patterns at the condyles and post-cam articulations were calculated during various activities. To test for feasibility, the technique was applied to a bicruciate posterior-stabilized prosthesis. Sensitivity of the finite element analysis, validation of the technique, and in vivo tests were performed. To test for potential in the clinical setting, five patients were preliminarily analyzed during chair rising-sitting, stair climbing, and step up-down. For each task and patient, the condylar contact points and contact line rotation were calculated. The results were repeatable and consistent with corresponding calculations from traditional fluoroscopic analysis. Specifically, natural knee kinematics, which shows rolling back and screw home, seemed replicated in all motor tasks. Post-cam contact was observed on both the anterior and posterior faces. Anterior contact is limited to flexion angle close to extension; posterior contact occurs in deeper flexion but is dependent on the motor task. The data suggest the proposed technique provides reliable information to analyze post-cam contacts. © 2009 The Association of Bone and Joint Surgeons®.

Vandenneucker H.,University Hospital Leuven | Labey L.,European Center for Knee Research | Victor J.,Ghent University | Vander Sloten J.,Catholic University of Leuven | And 2 more authors.
Knee Surgery, Sports Traumatology, Arthroscopy | Year: 2014

Methods: Six fresh-frozen cadavers were fixed on a custom-made mechanical knee rig. Full 3D kinematics was analysed during passive flexion–extension cycles, open chain extension, with and without mechanical resistance, as well as deep knee squats, using infrared motion capture cameras and retroflective markers. Measurements were taken for the native knee and after prosthetic trochlear resurfacing with and without patellar resurfacing in three different patellar thicknesses.Purpose: Although controversy still remains, isolated patellofemoral arthroplasty recently gained in popularity as a treatment option for patellofemoral osteoarthritis. It has compared to total knee arthroplasty the advantage of preserving the tibiofemoral articulation, which in theory would allow the preservation of natural tibiofemoral kinematics. Today, however, no data exist to support this assumption. This study was therefore performed in order to investigate the effect of isolated patellofemoral arthroplasty on the native three-dimensional tibiofemoral kinematic behaviour and whether a change in patellar thickness would have an influence.Results: Compared to the natural knee, patellofemoral arthroplasty resulted in significant changes in tibiofemoral kinematics, which were most pronounced in the most loaded motor tasks. Increased internal tibial rotation was noted in the mid- and high flexion ranges, reaching at 120° of flexion a mean difference of 4.5° ± 4.3° (p < 0.0001) during squat motion, over the whole flexion range during open chain motion and in deeper flexion beyond 50° (mean at 70°, 1.9° ± 3.7°) during resisted open chain. During squats, also, a more posterior translation of the lateral femoral condyle was observed. The effect was accentuated in case of patella overstuffing, whereas kinematics was closer to normal with patellar thinning.Conclusion: Isolated patellofemoral arthroplasty alters natural tibiofemoral kinematics, and the effects become more pronounced in case of increased patellar thickness. Therefore, it might be recommended to aim for a slight over-resection of patellar bone if sufficient bone stock is available. © 2014, Springer-Verlag Berlin Heidelberg.

Innocenti B.,European Center for Knee Research | Pianigiani S.,University of Florence | Labey L.,European Center for Knee Research | Victor J.,AZ St Lucas | Bellemans J.,Catholic University of Leuven
Journal of Biomechanics | Year: 2011

Total knee arthroplasty (TKA) is a very successful procedure, but pain or difficulties during activities still persist in patients. Patient outcomes in TKA surgery can be affected by implant design, alignment or patient-related anatomical factors. This paper presents a numerical sensitivity analysis of several TKA types: a fixed bearing, posterior stabilized prosthesis, a high flexion fixed bearing guided motion prosthesis, a mobile bearing prosthesis and a hinge prosthesis. Each prosthesis was virtually implanted on the same cadaver leg model and it underwent a loaded squat, in 10. s, between 0° and 120°, similar to several previous experimental tests performed on knee kinematics simulators. The aim of this examination was to investigate the sensitivity of the patello-femoral (PF) and tibio-femoral (TF) contact forces to patient-related anatomical factors, and component position in the different implant types. The following parameters were used for the sensitivity study: the proximo-distal patellar position, the patellar component tilting, the tibial component position and orientation, the locations of the medial and lateral collateral ligaments with respect to femur and tibia and the patellar tendon length. The sensitivity analysis showed that PF contact forces are mostly affected by patella height (increases up to 67% for one TKA type in patella-alta configuration), by an anterior tibial component translation (increases up to 30%), and by patellar component tilting (increases up to 29%); TF contact forces are mostly affected by the anterior displacement of the insertion points of the medial collateral ligament with respect to the reference position (increases up to 48%). © 2011 Elsevier Ltd.

Victor J.,AZ St Lucas | Labey L.,European Center for Knee Research | Wong P.,European Center for Knee Research | Innocenti B.,European Center for Knee Research | Bellemans J.,University Hospitals Leuven
Journal of Orthopaedic Research | Year: 2010

A comparative kinematics study was conducted on six cadaver limbs, comparing tibiofemoral kinematics in five conditions: unloaded, under a constant 130 N ankle load with a variable quadriceps load, with and without a simultaneous constant 50 N medial and lateral hamstrings load. Kinematics were described as translation of the projected centers of the medial (MFT) and lateral femoral condyles (LFT) in the horizontal plane of the tibia, and tibial axial rotation (TR) as a function of flexion angle. In passive conditions, the tibia rotated internally with increasing flexion to an average of -16° (range: -12/-20°, SD=3.0°). Between 0 and 408 flexion, the medial condyle translated forwards 4 mm (range: 0.8/5.5 mm, SD=2.5 mm), followed by a gradual posterior translation, totaling -9 mm (range: -5.8/ -18.5 mm, SD=4.9 mm) between 40-140° flexion. The lateral femoral condyle translated posteriorly with increasing flexion completing -25mm(range: -22.6 to -28.2 mm, SD=2.5 mm). Dynamic, loaded measurements simulating a deep knee bend were carried out in a knee rig. Under a fixed ankle load of 130 N and variable quadriceps loading, tibial rotation was inverted, mean TR=4.7° (range: -3.38/11.8° SD=5.4°), MFT=-0.5 mm (range:=-4.3/2.4 mm, SD=2.4 mm), LFT=3.3 mm (range:=-3.6/10.6 mm, SD=5.1 mm). Compared to the passive condition, all these excursions were significantly different (p≤0.015). Adding medial and lateral hamstrings force of 50 N each reduced TR, MFT, and LFT significantly compared to the passive condition. In general, loading the knee with hamstrings and quadriceps reduces rotation and translation compared to the passive condition. Lateral hamstring action is more influential on knee kinematics than medial hamstrings action. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

Vandenneucker H.,University Hospitals Leuven | Labey L.,European Center for Knee Research | Vander Sloten J.,Catholic University of Leuven | Desloovere K.,University Hospital Leuven | Bellemans J.,University Hospitals Leuven
Knee Surgery, Sports Traumatology, Arthroscopy | Year: 2014

Purpose: The objectives of this in vitro project were to compare the dynamic three-dimensional patellofemoral kinematics, contact forces, contact areas and contact pressures of a contemporary patellofemoral prosthetic implant with those of the native knee and to measure the influence of patellar resurfacing and patellar thickness. The hypothesis was that these designs are capable to reproduce the natural kinematics but result in higher contact pressures.Methods: Six fresh-frozen specimens were tested on a custom-made mechanical knee rig before and after prosthetic trochlear resurfacing, without and with patellar resurfacing in three different patellar thicknesses. Full three-dimensional kinematics were analysed during three different motor tasks, using infrared motion capture cameras and retroflective markers. Patellar contact characteristics were registered using a pressure measuring device.Results: The patellofemoral kinematic behaviour of the patellofemoral arthroplasty was similar to that of the normal knee when the patella was resurfaced, showing only significant (p < 0.0001) changes in patellar flexion. Without patellar resurfacing, significant more patellar flexion, lateral tilt and lateral rotation was noticed. Compared to the normal knee, contact pressures were significantly elevated after isolated trochlear resurfacing. However, the values were more than doubled after patellar resurfacing. Changes in patellar thickness only influenced the antero-posterior patellar position. There was no other influence on the kinematics, and only a limited influence on the contact pressures in the low flexion angles.Conclusion: The investigated design reproduced the normal patellofemoral kinematics acceptable well when the patella was resurfaced. From a kinematic point of view, patellar resurfacing may be advisable. However, the substantially elevated patellar contact pressures remain a point of concern in the decision whether or not to resurface the patella. This study therefore not only adds a new point in the discussion whether or not to resurface the patella, but also supports the claimed advantage that a patellofemoral arthroplasty is capable to reproduce the natural knee kinematics. © 2014 European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA)

Verlinden C.,University Hospital Leuven | Uvin P.,University Hospital Leuven | Labey L.,University Hospital Leuven | Labey L.,European Center for Knee Research | And 4 more authors.
Journal of Bone and Joint Surgery - Series B | Year: 2010

Malrotation of the femoral component is a cause of patellofemoral maltracking after total knee arthroplasty. Its precise effect on the patellofemoral mechanics has not been well quantified. We have developed an in vitro method to measure the influence of patellar maltracking on contact. Maltracking was induced by progressively rotating the femoral component either internally or externally. The contact mechanics were analysed using Tekscan. The results showed that excessive malrotation of the femoral component, both internally and externally, had a significant influence on the mechanics of contact. The contact area decreased with progressive maltracking, with a concomitant increase in contact pressure. The amount of contact area that carries more than the yield stress of ultra-high molecular weight polyethylene significantly increases with progressive maltracking. It is likely that the elevated pressures noted in malrotation could cause accelerated and excessive wear of the patellar button. ©2010 British Editorial Society of Bone and Joint Surgery.

Seitlinger G.,General Hospital Oberndorf | Seitlinger G.,General and Orthopaedic Hospital Stolzalpe | Scheurecker G.,Institute for CT and MR Imaging Am Schillerpark | Hogler R.,General and Orthopaedic Hospital Stolzalpe | And 3 more authors.
American Journal of Sports Medicine | Year: 2012

Background: In patients with patellar instability, a pathological tibial tubercle-trochlear groove (TT-TG) distance is a risk factor. However, the TT-TG distance gives no information about the location of the malformation.Hypothesis: Not all patients with a pathological TT-TG distance (≥20 mm) had lateralization of the tibial tubercle.Study Design: Cohort study (diagnosis); Level of evidence, 2.Methods: Fifty-eight knees in 49 patients with 2 or more patellar dislocations and 60 knees in 30 volunteers with no history of dislocation were analyzed using magnetic resonance imaging (MRI). The tibial tubercle-posterior cruciate ligament (TT-PCL) distance was defined as the mediolateral distance between the tibial tubercle midpoint and the medial border of the posterior cruciate ligament. The distance was measured parallel to the dorsal aspect of the proximal tibia (dorsal tibia condylar line). Three observers performed the measurements. Significant differences in the TT-PCL distance between the patient and the control group were estimated using an unpaired t test. The inter- and intraobserver variability of the measurement was performed.Results: The intraclass correlation coefficients for inter- and intraobserver variability of the TT-PCL distance were higher than 0.74 and 0.93, respectively. A statistically significant difference (P <.05) was found between the TT-PCL distance in the control group (mean [SD], 18.4 [3.35] mm) and in patients (21.9 [4.30] mm). The mean (SD) TT-TG was 18.9 (5.16) mm in the patient group and 11.9 (4.67) mm in the control group (P <.05). In the control group, 95% had a TT-PCL distance <24 mm. In the patient group, 22 of 58 knee joints (38%) had a TT-PCL distance ≥24 mm. Seventeen of 40 knee joints (43%) with a TT-TG distance ≥20 mm had a TT-PCL distance <24 mm.Conclusion: Only 57% of the patients with a pathological TT-TG distance (≥20 mm) had lateralization of the tibial tubercle in relation to the posterior cruciate ligament. The TT-PCL distance is an alternative method for determining the position of the tibial tubercle. © 2012 The Author(s).

Seitlinger G.,General Hospital Oberndorf | Seitlinger G.,General and Orthopaedic Hospital Stolzalpe | Scheurecker G.,Institute for CT and MR Imaging am Schillerpark | Hogler R.,General and Orthopaedic Hospital Stolzalpe | And 3 more authors.
Knee Surgery, Sports Traumatology, Arthroscopy | Year: 2014

Purpose: The aim of this study was to measure the tibia tubercle trochlea groove distance (TT–TG) as a function of knee flexion. Our hypothesis was that there is a different pattern in healthy volunteers and patients with patella instability (PFI).Methods: Thirty-six knees of 30 patients with at least one dislocation of the patella and 30 knees of 30 healthy volunteers as control group were analysed with magnetic resonance imaging by three different observers. The TT–TG was measured in steps of 15° between 0° and 90° of knee flexion. Furthermore, the alignment of the leg (MA), the femur torsion (FTor) and the tibia torsion (TTor) was calculated.Results: The TT–TG was higher in patients compared to volunteers and in extension compared to flexion. This difference was statistically significant (p < 0.05). Most of the patients with a TT–TG above 20 mm in extension showed a high decrease in flexion to normal values. In some patients, this compensating mechanism fails. MA, FTor and TTor were not different in patients and control group (n.s.).Conclusion: The TT–TG distance is dynamic and decreased significantly during flexion in knees with PFI and healthy volunteers. However, there were a small number of patients in the PFI group where this compensation mechanism did not work. Therefore, the decision to perform a tibia tubercle osteotomy should not be based on one single measurement in extension or 30° of knee flexion.Level of evidence: II. © 2014, Springer-Verlag Berlin Heidelberg.

Tibesku C.O.,Sporthopaedicum Straubing | Innocenti B.,European Center for Knee Research | Wong P.,European Center for Knee Research | Salehi A.,Smith and Nephew Inc. | Labey L.,European Center for Knee Research
Archives of Orthopaedic and Trauma Surgery | Year: 2012

Purpose: Long-term success of contemporary total knee replacements relies to a large extent on proper implant alignment. This study was undertaken to test whether specimen-matched cutting blocks based on computed axial tomography (CT) scans could provide accurate rotational alignment of the femoral component. Methods: CT scans of five fresh frozen full leg cadaver specimens, equipped with infrared reflective markers, were used to produce a specimen-matched femoral cutting block. Using those blocks, the bone cuts were made to implant a bi-compartmental femoral component. Rotational alignment of the components in the horizontal plane was determined using an optical measurement system and compared with all relevant rotational reference axes identified on the CT scans. Results: Average rotational alignment for the bi-compartmental component in the horizontal plane was 1.9° (range 0°-6.3°; standard deviation 2.6°). One specimen that showed the highest deviation from the planned alignment also featured a completely degraded medial articular surface. Conclusions: The CT-based specimen-matched cutting blocks achieved good rotational alignment accuracy except for one specimen with badly damaged cartilage. In such cases, imaging techniques that visualize the cartilage layer might be more suitable to design cutting blocks, as they will provide a better fit and increased surface support. © 2011 Springer-Verlag.

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