Viruez-Soto J.A.,Hospital General Of Mexico Dr Eduardo Liceaga |
Vallejo-Narvaez C.M.,Hospital General Of Mexico Dr Eduardo Liceaga |
Torrez-Morales F.,Hospital General Of Mexico Dr Eduardo Liceaga |
Briones-Vega C.G.,Institute Genetica y Fertilidad |
And 2 more authors.
Gaceta Mexicana de Oncologia | Year: 2014
Insulinoma is the most frequent neuroendocrine pancreatic tumor with an estimated incidence of 1-4 cases per million of habitants by year, with a lower incidence during pregnancy with no more of 30 cases reported in the literature. The objective is to relate a case of insulinoma treated successfully in 18-year-old patient with 16.5-week pregnancy. A 31-year-old patient, with dizziness 3 years ago associated to tonic-clonic seizures, pregnancy was confirmed and was transferred to the Critical Care Obstetrics Unit of the Hospital General de México "Dr. Eduardo Liceaga". Endogenous hyperinsulinism was confirmed. She received glucose solution. Magnetic resonance and endoscopic ultrasound were performed. A therapeutic reunion including Biliopancreatic Surgery, Endocrinology, Perinatology and Critical Care Obstetrics was performed, with ulterior surgical treatment with enucleation of the 2.5 x 2 x 2 cm insulinoma located in the head of pancreas. The infusion of glucose solution was interrupted progressively with acceptable glycemic values. The patient was transferred to perinatology with viable pregnancy of 18.5-week. The histopathology as the immunohistochemical test confirmed insulinoma. This case shows the importance of the insulinoma diagnosis in a young pregnant woman during the second trimester with clinical data of hypoglycemia and multidisciplinary consensus of surgical treatment at an opportune moment, avoiding this way an indirect maternal death and fetal morbi-mortality. © 2014 Gaceta Mexicana de Oncología.