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Ngadiarti I.,Politeknik Kesehatan Kemenkes Jakarta 2 | Ngadiarti I.,Esa Unggul University | Kusharto C.M.,Bogor Agricultural University | Briawan D.,Bogor Agricultural University | And 2 more authors.
Pakistan Journal of Nutrition | Year: 2013

The relationship between fatty acid composition with levels of amyloid beta and tau proteins in the cerebrospinal fluid is not widely known. The aim of this study was to assess the influence of catfish oil (CFO) and fermented catfish oil (FCFO) on cognitive functions (biology markers) aged female cynomolgus monkey (Cynomolgus fascicularis). Twelve aged female Cynomolgus were divided into 4 groups, each were fed with atherogenic iso calory with 0.2% cholesterol and 30% E (12% w/w), 3% from soybean oil, 9% from different fat sources, beeftallow (BFT), catfish oil (CFO), fermented cat fish oil (FCFO) and soybean oil (SBO). Cerebrospinal fluid was taken through suboccipital then kept at 20°C. Cognitive biology markers which were analyzed by using Tau and A[342ELISA kits. Changes in level of amyloid beta, tau protein and ratio of tau protein and amyloid beta were not statistically significant in the cynomolgus group four that were fed with BFT, FCFO, CFO and SBO, despite a trend toward increased levels of amyloid beta and decreased level of the tau protein /amyloid beta ratio were found in the group given with FCFO and CFO. In summary, FCFO and CFO intake capable to improve the cognitive function based on biological biomarkers. © Asian Network for Scientific Information, 2013.


Sandjaja,National Health Research Institute | Sandjaja,Indonesian Nutrition Foundation for Food Fortification formerly Koalisi Fortifikasi Indonesia | Jusat I.,Indonesian Nutrition Foundation for Food Fortification formerly Koalisi Fortifikasi Indonesia | Jusat I.,Esa Unggul University | And 9 more authors.
Public Health Nutrition | Year: 2015

Objective To assess oil consumption, vitamin A intake and retinol status before and a year after the fortification of unbranded palm oil with retinyl palmitate. Design Pre-post evaluation between two surveys. Setting Twenty-four villages in West Java. Subjects Poor households were randomly sampled. Serum retinol (adjusted for subclinical infection) was analysed in cross-sectional samples of lactating mothers (baseline n 324/endline n 349), their infants aged 6-11 months (n 318/n 335) and children aged 12-59 months (n 469/477), and cohorts of children aged 5-9 years (n 186) and women aged 15-29 years (n 171), alongside food and oil consumption from dietary recall. Results Fortified oil improved vitamin A intakes, contributing on average 26 %, 40 %, 38 %, 29 % and 35 % of the daily Recommended Nutrient Intake for children aged 12-23 months, 24-59 months, 5-9 years, lactating and non-lactating women, respectively. Serum retinol was 2-19 % higher at endline than baseline (P<0·001 in infants aged 6-11 months, children aged 5-9 years, lactating and non-lactating women; non-significant in children aged 12-23 months; P=0·057 in children aged 24-59 months). Retinol in breast milk averaged 20·5 μg/dl at baseline and 32·5 μg/dl at endline (P<0·01). Deficiency prevalence (serum retinol <20 μg/dl) was 6·5-18 % across groups at baseline, and 0·6-6 % at endline (P≤0·011). In multivariate regressions adjusting for socio-economic differences, vitamin A intake from fortified oil predicted improved retinol status for children aged 6-59 months (P=0·003) and 5-9 years (P=0·03). Conclusions Although this evaluation without a comparison group cannot prove causality, retinyl contents in oil, Recommended Nutrient Intake contributions and relationships between vitamin intake and serum retinol provide strong plausibility of oil fortification impacting vitamin A status in Indonesian women and children. © The Authors 2015.


Anindita R.,Esa Unggul University
Advanced Science Letters | Year: 2015

This research aims to observe how Knowledge Sharing level correlates with the implementation of Learning Organization in both People and Structure Levels. This topic may help those Private Universities to improve their learning capacities and transform into organizations which are able to facilitate their members to develop learning culture so they will have adequate capacities to perform some innovations, foster the development of their organizations, and share valuable knowledge. By doing so, such organization will continuously transform (Peddler, 1998; Dale, 2003), so it has certain capacities to perform some innovations and grow the level of its development (Watkins and Marsick, 1993, 1994, 2003). Slightly different with the above-mentioned statements, Veisi, et al. (2012) stated that the individuals or members of higher education institutions will determine whether such institution will develop into a learning organization or not. Thus, we need to distinguish between the learning organization for individuals and for management board, even though those individuals, teams, and organization shall jointly establish an ‘embedded’ system (Kumar, 2005). The findings of this research evidences that the implementation of Learning Organization in People level bring significant and positive influence towards the implementation of Learning organization in Structure level. Learning Organization in People level also gives meaningful and positive contribution towards the level of knowledge sharing, which has been either directly or indirectly integrated through organization commitment. On the contrary, Learning Organization in Structure level does not contribute any meaningful impact towards the level of knowledge but such component can still affect knowledge sharing when it is integrated through the organization commitment. © 2015 American Scientific Publishers. All rights reserved.


Sandfreni S.,Esa Unggul University | Surendro I.K.,Bandung Institute of Technology
MATEC Web of Conferences | Year: 2016

Requirements engineering approach through intentional perspective is one of the arguments that appear in the field of requirement engineering. That approach can explain the characteristics of the behavior of an actor. The usage Goal Based Workflow and KAOS method in iStar modeling might help the system analyst to gain knowledge about the internal process inside each of actor sequentially, such that the whole sequential activity to achieve the goal are exposed clearly in those actor's internal process. The adoption of the concept of the role of RACI diagram on Role Based Goal Oriented Model system analyst gain complete knowledge about requirements of actor who involve in a system. System analyst might also distinguish the dependency between each actor in each process. Those dependencies are exhibited in strategic dependency model. In addition, the internal activities of the actor are also shown in strategic rationale model. © Owned by the authors, published by EDP Sciences, 2016.


Munawar,Esa Unggul University | Salim N.,University of Technology Malaysia | Ibrahim R.,University of Technology Malaysia
Proceedings - 2014 International Conference on Advanced Informatics: Concept, Theory and Application, ICAICTA 2014 | Year: 2014

Data warehouse (DW) integrates data from external and internal sources not only for storage purposes but also for analythical query processing. As this information is to be used for business intelligent, it makes the design of DW difficult task. Requirements analysis is the foundation for the development of a DW. Ensuring quality in requirements analysis is an importance task to minimize the risk of failure in a DW project. However, quality issues in DW requirements analysis have not given much attention in the literature. In this paper we have advocated the integration of quality and multi-driven approach (goal-driven, user-driven, data-driven, process-driven and external-driven) as an explicit stage in the DW development to reduce failure risk of DW. © 2014 IEEE.


Adikara F.,Esa Unggul University | Adikara F.,Bandung Institute of Technology | Wijaya P.D.,Esa Unggul University | Hendradjaya B.,Bandung Institute of Technology | Sitohang B.,Bandung Institute of Technology
Lecture Notes in Electrical Engineering | Year: 2016

In the previous research[1, 2], the use of Key Performance Indicators (KPIs) was proposed as a controlling tool for IT goal, which extracted from organization goal. The goals are the analysis and refinement using Case Based Reasoning (CBR) methods to get more qualified system requirements. This paper aims to illustrate the use of the IT goals and KPIs in the requirement engineering process that produced a Goal Tree Model, which would subsequently be used in an information system design using the Unified Modeling Language (UML). Through requirement engineering process with KPIs as the system’s success parameter in achieving the goals derived from the organization goals, this paper seeks to demonstrate the improvement in the quality of the designed system. Also included in this research is how the results of the requirement engineering process produces a system that fulfill the KPIs without basing the system’s requirements on the user, to reduce the risk of the occurrence of user’s needs in the process of requirement elicitation. We have applied the proposed process to a development of an information system as a case study. © Springer Science+Business Media Singapore 2016.


Eff A.R.Y.,Esa Unggul University | Rahayu S.T.,Esa Unggul University
Asian Journal of Pharmaceutical and Clinical Research | Year: 2016

Objectives: The research was aimed to assess the effect of essential oil of Galangal rhizome (Alpinia galanga (Linn.) Pierre.) in vivo by Widal test using mice infected with Salmonella typhi. Methods: Antibacterial activity of the essential oils was determined by Widal test for measuring antibody titre of Salmonella antigen. Study was begun by isolating the essential oils galangal rhizome (Alpinia galanga (Linn.) Pierre.) followed by tested the antibacterial activity of Salmonella typhi in rats (Rattus norvegicus L.). Mice were divided into six treatment groups, ie normal control group, negative control group given Gum Arabic 10%, positive control group given the suspension of chloramphenicol 8 mg/250 g BW, experimental group 1 given the emulsion of essential oil at the dose 25 mg / ml, experimental group given the emulsion of essential oil at the dose 50 mg / ml, and the experimental group 3 given the emulsion of essential oil at the dose 75 mg / ml. Before treated, mice were adapted for 2 weeks and measurement of antibody titer (Widal test 1) as a baseline, then the mice induced by Salmonella typhi suspension oral. On day 8 titre antibody was measuring (Widal test 2) and followed the administration of the test material orally 3 times a day for 7 consecutive days - respectively. On day 14 measurements of antibody titer was repeated (Widal test 3) to see the effectiveness of treatment. Results: An essential oil from Galangal (Alpinia galanga (Linn.) Pierre.) at the dose 25mg/ml, 50 mg/ml and 75 mg/ml can reduce antibody titer of Salmonella antigen. Conclusion: The results obtained in the study show that essential oils from galangal rhizome possess antibacterial effect against Salmonella typhi. © 2016, Innovare Academics Sciences Pvt. Ltd. All rights reserved.


PubMed | Esa Unggul University and National Health Research Institute
Type: Journal Article | Journal: Asia Pacific journal of clinical nutrition | Year: 2016

Vitamin A deficiency is particularly common among children younger than 5 years. In 2011, a study conducted in West Java revealed that the prevalence of vitamin A deficiency in children aged 6-11 months, 12-23 months, and 24-59 months was 18.2%, 15.2%, and 9.9%, respectively. The present study analysed the differences in vitamin A intake and serum retinol in all the preschool children from Grobogan and Kudus, Central Java.The baseline data of vitamin A efficacy were analysed. A total of 143 children aged 1-3 years participants (n=71 from Kudus and n=71 from Grobogan) were recruited and we used independent t-tests to analyse the data.Among the study population, 50.7% and 48.6% were boys and 49.3% and 51.4% were girls from Kudus and Grobogan, respectively. The average intake of energy, carbohydrates, protein, fat, and vitamin A was 698440 (Kcal), 8960 (g), 25.918.5 (g), 26.118.5 (g), and 435.3554.0 (g) in Kudus and 868493 (Kcal), 10967 (g), 30.920.1 (g), 35.123.1 (g), and 538.1622.9 (g) in Grobogan, respectively. The average serum retinol in Kudus and Grobogan were 26.76.4 (g/dL) and 29.65.9 (g/dL), respectively. Significant differences in energy and fat intake (p<0.05) were also observed between the Kudus and Grobogan districts; however, no differences in protein, carbohydrates, and vitamin A intake (p>=0.05) were noted. A significant difference in serum retinol was observed between these two districts (p<0.05).An increase in vitamin A intake through various foods should improve the serum retinol in preschool children.

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