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Mehari F.,Erlangen Graduate School In Advanced Optical Technologies Saot Friedrich Alexander University Erlangen Nurnberg Paul Gordan Str 6 91052 Erlangen Germany | Kanawade R.,Erlangen Graduate School In Advanced Optical Technologies Saot Friedrich Alexander University Erlangen Nurnberg Paul Gordan Str 6 91052 Erlangen Germany | Adler W.,Chair of Biometry and Epidemiology Friedrich Alexander University Erlangen Nurnberg Waldstrasse 6 91054 Erlangen Germany | Klampfl F.,Institute Of Photonics Technologies Friedrich Alexander University Erlangen Nurnberg Konrad Zuse Str 3 5 91052 Erlangen Germany | And 2 more authors.
Journal of Biophotonics | Year: 2016

In the present study, the elemental compositions of fat and nerve tissue during their plasma mediated laser ablation are studied in the context of tissue differentiation for laser surgery applications by using Laser-Induced Breakdown Spectroscopy (LIBS). Tissue samples of porcine fat and nerve were prepared as ex vivo experimental objects. Plasma mediated laser ablation is performed using an Nd:YAG laser in open air and under normal stray light conditions. The performed measurements suggest that the two tissue types show a high similarity in terms of qualitative elemental composition while at the same time revealing a distinct difference in the concentration of the constituent elements. Different analysis approaches are evaluated and discussed to optimize the tissue-differentiation performance of the LIBS approach. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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