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FRAMINGHAM, Mass.--(BUSINESS WIRE)--SCIEX, a global leader in life science analytical technologies, announced today that EPL Bio Analytical Services, (EPL BAS), an industry leading agriculture-focused analytical contract laboratory, has selected the SCIEX QTRAP® 6500+ with SelexION®+, enabling their researchers to provide analytical solutions to customers with projects involving difficult matrices that the lab could not previously consider accepting. EPL’s analytical laboratory provides customized analytical laboratory testing services to the agricultural crop protection, agricultural chemical, agricultural biotechnology, organic, biocontrol, nutritional, food ingredient, and feed industries and they partner with customers from around the world to provide safe and reliable agricultural products to local and global consumers. EPL’s installation of the SCIEX QTRAP 6500+ LC-MS/MS system with multi-component IonDrive™ Technology and a newly designed IonDrive High Energy Detector+, offers them the high sensitivity, reliability and confidence they require to produce data as objective evidence for the efficacy and safety of a wide range agricultural product, including organic products, synthetic chemistry and plant incorporated protectants. The QTRAP 6500+ system delivers enhanced selectivity, without compromising MRM sensitivity, for more flexibility in dealing with complex interferences. The exclusive QTRAP scan function of MS3 (MS/MS/MS), adds an additional level of mass filtering, while the SelexION+ ion mobility provides an orthogonal separation prior to mass separation and offers the lab yet another tool for eliminating isobaric background interferences in complex assays, making quantitation in complex samples easier and less time consuming. The unique scan functions offered by the SCIEX QTRAP system, including enhanced mass scans (EMS), enhanced resolution scans (ER), and enhanced product ion scans (EPI), deliver maximum flexibility and workflow options enabling researchers to embrace new discoveries and more accurate identification that extend beyond quantitation. “The 6500+ with SelexION allows EPL Bio Analytical Services to have unique product offering and provides a significant competitive advantage that enables their researchers to solve problems other labs cannot,” said Paul Winkler, Food and Beverage Marking Development Manager, Americas at SCIEX. “The acquisition of the QTRAP 6500+ provides EPL Bio Analytical Services with an instrument that has better low mass negative ion performance than their competitors’ laboratories, and with the addition of SelexION, EPL Bio Analytical Services further extends their ability to perform analyses in complex matrices such as environmental and agricultural samples.” “At EPL, the management and staff place a high value on being the industry leader,” said Fred Claussen, VP of Method Development EPL Bio Analytical Services. “When we find a technology that will provide better data to our customers, we go get it. In the competitive world of contract laboratories, having the best technology, along with the best technical staff allows us to more effectively compete for new business and uphold our strong brand on a global level. We believe that the acquisition of these SCIEX solutions gives our laboratory this important competitive edge.” Learn more about SCIEX QTRAP and SelexION Technology SCIEX helps to improve the world we live in by enabling scientists and laboratory analysts to find answers to the complex analytical challenges they face. The company's global leadership and world-class service and support in the capillary electrophoresis and liquid chromatography-mass spectrometry industry have made it a trusted partner to thousands of the scientists and lab analysts worldwide who are focused on basic research, drug discovery and development, food and environmental testing, forensics and clinical research. With over 40 years of proven innovation, SCIEX excels by listening to and understanding the ever-evolving needs of its customers to develop reliable, sensitive and intuitive solutions that continue to redefine what is achievable in routine and complex analysis. For more information, please visit sciex.com. For Research Use Only. Not for use in diagnostic procedures. RUO-MKT-12-6044-A ©2017 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB Sciex™ is being used under license. EPL Bio Analytical Services (EPL BAS) is an award-winning, Good Laboratory Practice compliant (GLP), ISO 17025-accredited analytical contract lab. Our vision is to be the “most trusted analytical laboratory in the Ag Industry.” EPL BAS serves the global agricultural industry by analyzing feed and food ingredients, organic products, genetically enhanced crops, bio-pesticides, plants, algae, plant protection agents and crop chemicals. With the goal of providing safe, healthy, and abundant food while protecting and improving the environment, EPL BAS uses advanced innovative technology in the areas of nutritional chemistry, agricultural chemistry, including residue and product chemistry, and molecular biology to provide excellent, timely support for the feed, food, fiber and fuel industries. We don’t have an Ag Division…because we are Ag! Visit us at www.eplbas.com, Facebook, LinkedIn and Twitter.


Berman K.H.,Monsanto Corporation | Harrigan G.G.,Monsanto Corporation | Riordan S.G.,Monsanto Corporation | Nemeth M.A.,Monsanto Corporation | And 5 more authors.
Journal of Agricultural and Food Chemistry | Year: 2010

Brazil has become one of the largest soybean producers. Two Monsanto Co. biotechnology-derived soybean products are designed to offer benefits in weed and pest management. These are second-generation glyphosate-tolerant soybean, MON 89788, and insect-protected soybean, MON 87701. The second-generation glyphosate-tolerant soybean product, MON 89788, contains the 5-enolpyruvylshikimate-3-phosphate synthase gene derived from Agrobacterium sp. strain CP4 (cp4 epsps). MON 87701 contains the cry1Ac gene and expression of the Cry1Ac protein providing protection from feeding damage caused by certain lepidopteran insect pests. The purpose of this assessment was to determine whether the compositions of seed and forage of MON 89788 and MON 87701 are comparable to those of conventional soybean grown in two geographically and climatically distinct regions in multiple replicated sites in Brazil during the 2007-2008 growing season. Overall, results demonstrated that the seed and forage of MON 89788 and MON 87701 are compositionally equivalent to those of conventional soybean. Strikingly, the results also showed that differences in mean component values of forage and seed from the two controls grown in the different geographical regions were generally greater than that observed in test and control comparisons. Hierarchical cluster analysis (HCA) and principal component analysis (PCA) of compositional data generated on MON 89788, MON 87701, and their respective region-specific controls provide a graphical illustration of how natural variation contributes more than biotechnology-driven genetic modification to compositional variability in soybean. Levels of isoflavones and fatty acids were particularly variable. © 2010 American Chemical Society.


Claussen F.A.,EPL Bio Analytical Services | Taylor M.L.,Monsanto Corporation | Breeze M.L.,Monsanto Corporation | Liu K.,Monsanto Corporation
Journal of Agricultural and Food Chemistry | Year: 2015

Plant oils, including canola oil, are considered to be major sources of vitamin K as the second most substantial contributor of vitamin K to the human diet. Green leafy vegetables are the largest source of vitamin K. However, the effects of environment and germplasm on vitamin K levels in harvested canola seed have not been extensively investigated. To better understand these relationships, harvested canola seed from a range of diverse cultivars grown in different geographical locations in North and South America was assessed for levels of vitamin K. The analytical method developed to perform this measurement was based on C30 reversed-phase HPLC that could distinguish the biologically active trans-vitamin K1 from the inactive cis-isomer. Results demonstrated that for the majority of the canola cultivars evaluated, those cultivated in the North American sites had higher average vitamin K1 levels than those cultivated in the South American sites. Not all of the cultivars exhibited differences in response to the environment, suggesting that individual cultivar genetics also played a role in the variability of vitamin K1 levels observed in canola seed. Results from this study suggest that cultivar and environmental effects influence vitamin K1 levels in canola seed and provide a context to assess compositional variability of new cultivars. © 2015 American Chemical Society.


Cong B.,DuPont Pioneer | Maxwell C.,DuPont Pioneer | Luck S.,DuPont Pioneer | Vespestad D.,Eurofins | And 3 more authors.
Journal of Agricultural and Food Chemistry | Year: 2015

This study was designed to assess natural variation in composition and metabolites in 50 genetically diverse non genetically modified maize hybrids grown at six locations in North America. Results showed that levels of compositional components in maize forage were affected by environment more than genotype. Crude protein, all amino acids except lysine, manganese, and β-carotene in maize grain were affected by environment more than genotype; however, most proximates and fibers, all fatty acids, lysine, most minerals, vitamins, and secondary metabolites in maize grain were affected by genotype more than environment. A strong interaction between genotype and environment was seen for some analytes. The results could be used as reference values for future nutrient composition studies of genetically modified crops and to expand conventional compositional data sets. These results may be further used as a genetic basis for improvement of the nutritional value of maize grain by molecular breeding and biotechnology approaches. © 2015 American Chemical Society.

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