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Forrester M.B.,Environmental Epidemiology and Disease Registries Section
Journal of Addictive Diseases | Year: 2012

Opioid analgesic abuse is an increasing problem in the United States. All opioid analgesic abuse exposures reported to Texas poison centers during 2000-2010 were identified and annual and geographic patterns were examined. The annual number of opioid analgesic abuse cases increased 160% from 441 in 2000 to 1,145 in 2010. The proportion of total opioid analgesic exposures reported to be due to abuse increased 55% from 11.4% in 2000 to 17.8% in 2010. The opioid analgesic rate per 100,000 was highest (90.15) in northeastern Texas and lowest (27.91) in the southern part of the state. Copyright © Taylor & Francis Group, LLC. Source


Forrester M.B.,Environmental Epidemiology and Disease Registries Section
Human and Experimental Toxicology | Year: 2016

Poison centers advance knowledge in the field of toxicology through publication in peer-review journals. This investigation describes the pattern of poison center-related publications. Cases were poison center-related research published in peer-review journals during 1995-2014. These were identified through searching the PubMed database, reviewing the tables of contents of selected toxicology journals, and reviewing abstracts of various national and international meetings. The following variables for each publication were identified: year of publication, journal, type of publication (meeting abstract vs. other, i.e. full article or letter to the editor), and the country(ies) of the poison center(s) included in the research. Of the 3147 total publications, 62.1% were meeting abstracts. There were 263 publications in 1995-1999, 536 in 2000-2004, 999 in 2005-2009, and 1349 in 2010-2014. The publications were in 234 different journals. The journals in which the highest number of research was published were Clinical Toxicology (69.7%), Journal of Medical Toxicology (2.2%), and Veterinary and Human Toxicology (2.1%). The research was reported from 62 different countries. The countries with the highest number of publications were the United States (67.9%), United Kingdom (6.5%), Germany (3.9%), France (2.5%), and Italy (2.4%). The number of publications increased greatly over the 20 years. Although the publications were in a large number of journals, a high proportion of the publications were in one journal. While the research came from a large number of countries, the preponderance came from the United States. © 2016 The Author(s). Source


Forrester M.B.,Environmental Epidemiology and Disease Registries Section
Journal of Addictive Diseases | Year: 2011

Dextromethorphan abuse is increasing in United States. Intentional misuse or abuse ingestions of dextromethorphan-containing products reported to Texas poison centers during 2000-2009 were identified and the distribution of ingestions by selected factors was determined. There were 3,421 total cases; Coricidin® (Schering-Plough Health Care Products, Inc., Memphis, TN) products were involved in 53.6% of cases. The number of cases increased during 2000-2002 and then declined during 2003-2005 before increasing again in 2006 and remaining relatively constant afterward. The majority of patients were male (60.4%) and between 13 and 19 years of age (69.0%). A potentially serious outcome was assigned in 46.2% of the cases and 83.1% were managed at a health care facility. Copyright © Taylor & Francis Group, LLC. Source


Forrester M.B.,Environmental Epidemiology and Disease Registries Section
Journal of Addictive Diseases | Year: 2011

The combination of hydrocodone, carisoprodol, and alprazolam is subject to abuse. Ingestions of this drug combination reported to Texas poison centers during 1998-2009 were identified (totaling 1,295 cases) and the distribution of ingestions by selected factors was determined. The number of cases increased from 0 in 1998 to 200 in 2007, and then decreased to 132 in 2009. The counties in eastern and southeastern Texas accounted for 80.9% of the cases. Of the patients, 57.3% were women and 94.6% were age 20 or older. Suspected attempted suicide accounted for 59.3% of the cases and intentional misuse or abuse for 27.3%. Copyright © Taylor & Francis Group, LLC. Source


Forrester M.B.,Environmental Epidemiology and Disease Registries Section
Journal of Addictive Diseases | Year: 2014

Use of 2-methoxybenzyl analogues of 2C-X phenethylamines (NBOMe) is increasing in the United States. Twenty-five NBOMe exposures reported to Texas poison centers during 2012-2013 were identified; 76% involved 25I-NBOMe, 12% involved 25C-NBOMe, and 12% involved an unknown NBOMe. Eighty-eight percent of the patients were men; mean age was 17 years (range, 14-25 years). The exposure route was 72% from ingestion alone, 12% from inhalation alone, 4% from ingestion and inhalation, and 12% from an unknown route. The most common clinical effects were tachycardia (52%), agitation (48%), hallucinations (32%), hypertension (32%), confusion (24%), and mydriasis (20%). Two patients died. Copyright © Taylor & Francis Group, LLC. Source

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