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Gracitelli C.P.B.,University of California at San Diego | Gracitelli C.P.B.,Federal University of Sao Paulo | Tatham A.J.,University of California at San Diego | Tatham A.J.,University of Edinburgh | And 8 more authors.
PLoS ONE | Year: 2015

Purpose To evaluate the ability of longitudinal Useful Field of View (UFOV) and simulated driving measurements to predict future occurrence of motor vehicle collision (MVC) in drivers with glaucoma. Design Prospective observational cohort study. Participants 117 drivers with glaucoma followed for an average of 2.1 ± 0.5 years. Methods All subjects had standard automated perimetry (SAP), UFOV, driving simulator, and cognitive assessment obtained at baseline and every 6 months during follow-up. The driving simulator evaluated reaction times to high and low contrast peripheral divided attention stimuli presented while negotiating a winding country road, with central driving task performance assessed as "curve coherence". Drivers with MVC during follow-up were identified from Department of Motor Vehicle records. Main Outcome Measures Survival models were used to evaluate the ability of driving simulator and UFOV to predict MVC over time, adjusting for potential confounding factors. Results Mean age at baseline was 64.5 ± 12.6 years. 11 of 117 (9.4%) drivers had a MVC during follow- up. In the multivariable models, low contrast reaction time was significantly predictive of MVC, with a hazard ratio (HR) of 2.19 per 1 SD slower reaction time (95% CI, 1.30 to 3.69; P = 0.003). UFOV divided attention was also significantly predictive of MVC with a HR of 1.98 per 1 SD worse (95% CI, 1.10 to 3.57; P = 0.022). Global SAP visual field indices in the better or worse eye were not predictive of MVC. The longitudinal model including driving simulator performance was a better predictor of MVC compared to UFOV (R2 = 0.41 vs R2 = 0.18). Conclusions Longitudinal divided attention metrics on the UFOV test and during simulated driving were significantly predictive of risk of MVC in glaucoma patients. These findings may help improve the understanding of factors associated with driving impairment related to glaucoma. Copyright: © 2015 Gracitelli et al. Source


Van Weverberg K.,Brookhaven National Laboratory | Van Weverberg K.,Catholic University of Louvain | Vogelmann A.M.,Brookhaven National Laboratory | Lin W.,Brookhaven National Laboratory | And 6 more authors.
Journal of the Atmospheric Sciences | Year: 2013

This paper presents a detailed analysis of convection-permitting cloud simulations, aimed at increasing the understanding of the role of parameterized cloud microphysics in the simulation of mesoscale convective systems (MCSs) in the tropical western Pacific (TWP). Simulations with three commonly used bulk microphysics parameterizations with varying complexity have been compared against satellite-retrieved cloud properties. An MCS identification and tracking algorithm was applied to the observations and the simulations to evaluate the number, spatial extent, and microphysical properties of individual cloud systems. Different from many previous studies, these individual cloud systems could be tracked over larger distances because of the large TWP domain studied. The analysis demonstrates that the simulation of MCSs is very sensitive to the parameterization of microphysical processes. The most crucial element was found to be the fall velocity of frozen condensate. Differences in this fall velocity between the experiments were more related to differences in particle number concentrations than to fall speed parameterization. Microphysics schemes that exhibit slow sedimentation rates for ice aloft experience a larger buildup of condensate in the upper troposphere. This leads to more numerous and/or larger MCSs with larger anvils. Mean surface precipitation was found to be overestimated and insensitive to the microphysical schemes employed in this study. In terms of the investigated properties, the performances of complex two-moment schemes were not superior to the simpler one-moment schemes, since explicit prediction of number concentration does not necessarily improve processes such as ice nucleation, the aggregation of ice crystals into snowflakes, and their sedimentation characteristics. © 2013 American Meteorological Society. Source


Tatham A.J.,University of California at San Diego | Boer E.R.,Technical University of Delft | Rosen P.N.,University of California at San Diego | Della Penna M.,Entropy Control Inc. | And 4 more authors.
American Journal of Ophthalmology | Year: 2014

Purpose: To examine the relationship between glaucomatous structural damage and ability to divide attention during simulated driving. Design: Cross-sectional observational study. Methods: setting : Hamilton Glaucoma Center, University of California San Diego. patient population : Total of 158 subjects from the Diagnostic Innovations in Glaucoma Study, including 82 with glaucoma and 76 similarly aged controls. observation procedure : Ability to divide attention was investigated by measuring reaction times to peripheral stimuli (at low, medium, or high contrast) while concomitantly performing a central driving task (car following or curve negotiation). All subjects had standard automated perimetry (SAP) and optical coherence tomography was used to measure retinal nerve fiber layer (RNFL) thickness. Cognitive ability was assessed using the Montreal Cognitive Assessment and subjects completed a driving history questionnaire. main outcome measures : Reaction times to the driving simulator divided attention task. Results: The mean reaction times to the low-contrast stimulus were 1.05 s and 0.64 s in glaucoma and controls, respectively, during curve negotiation (P < .001), and 1.19 s and 0.77 s (P = .025), respectively, during car following. There was a nonlinear relationship between reaction times and RNFL thickness in the better eye. RNFL thickness remained significantly associated with reaction times even after adjusting for age, SAP mean deviation in the better eye, cognitive ability, and central driving task performance. Conclusions: Although worse SAP sensitivity was associated with worse ability to divide attention, RNFL thickness measurements provided additional information. Information from structural tests may improve our ability to determine which patients are likely to have problems performing daily activities, such as driving. © 2014 Elsevier Inc. All rights reserved. Source


Abbink D.A.,Technical University of Delft | Mulder M.,Technical University of Delft | Van Der Helm F.C.T.,Technical University of Delft | Boer E.R.,Entropy Control Inc.
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics | Year: 2011

In previous research, a driver support system that uses continuous haptic feedback on the gas pedal to inform drivers of the separation to the lead vehicle was developed. Although haptic feedback has been previously shown to be beneficial, the influence of the underlying biomechanical properties of the driver on the effectiveness of haptic feedback is largely unknown. The goal of this paper is to experimentally determine the biomechanical properties of the ankle-foot complex (i.e., the admittance) while performing a car-following task, thereby separating driver responses to visual feedback from those to designed haptic feedback. An experiment was conducted in a simplified fixed-base driving simulator, where ten participants were instructed to follow a lead vehicle, with and without the support of haptic feedback. During the experiment, the lead vehicle velocity was perturbed, and small stochastic torque perturbations were applied to the pedal. Both perturbations were separated in the frequency domain to allow the simultaneous estimation of frequency response functions of both the car-following control behavior and the biomechanical admittance. For comparison to previous experiments, the admittance was also estimated during three classical motion control tasks (resist forces, relax, and give way to forces). The main experimental hypotheses were that, first, the haptic feedback would encourage drivers to adopt a give way to force task, resulting in larger admittance compared with other tasks and, second, drivers needed less control effort to realize the same car-following performance. Time-and frequency-domain analyses provided evidence for both hypotheses. The developed methodology allows quantification of the range of admittances that a limb can adopt during vehicle control or while performing a variety of motion control tasks. It thereby allows detailed computational driver modeling and provides valuable information on how to design and evaluate continuous haptic feedback systems. © 2011 IEEE. Source


Abbink D.A.,Technical University of Delft | Mulder M.,Technical University of Delft | Boer E.R.,Entropy Control Inc.
Cognition, Technology and Work | Year: 2012

Literature points to persistent issues in human-automation interaction, which are caused either when the human does not understand the automation or when the automation does not understand the human. Design guidelines for human-automation interaction aim to avoid such issues and commonly agree that the human should have continuous interaction and communication with the automation system and its authority level and should retain final authority. This paper argues that haptic shared control is a promising approach to meet the commonly voiced design guidelines for human-automation interaction, especially for automotive applications. The goal of the paper is to provide evidence for this statement, by discussing several realizations of haptic shared control found in literature. We show that literature provides ample experimental evidence that haptic shared control can lead to short-term performance benefits (e. g., faster and more accurate vehicle control; lower levels of control effort; reduced demand for visual attention). We conclude that although the continuous intuitive physical interaction inherent in haptic shared control is expected to reduce long-term issues with human-automation interaction, little experimental evidence for this is provided. Therefore, future research on haptic shared control should focus more on issues related to long-term use such as trust, overreliance, dependency on the system, and retention of skills. © 2011 The Author(s). Source

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