Zelenograd, Russia
Zelenograd, Russia

Time filter

Source Type

News Article | May 31, 2017
Site: www.prnewswire.co.uk

The Summit was organised by the European Liver Patients' Association, in partnership with the European Association for the Study of the Liver. The event took place in the European Parliament (Brussels) and was hosted by Alojz Peterle, Member of the European Parliament. Participants explored potential measures to reduce the burden of the disease and to mitigate the impact that NAFLD-NASH will have on the sustainability of healthcare systems. "The seriousness of NAFLD and the potential impact it will have on healthcare systems needs to be recognised and addressed before we encounter an epidemic across Europe," stated Tatjana Reic, President of ELPA. NAFLD, which has become the most common chronic liver disorder in Europe and the U.S., and NASH are seen as lifestyle conditions. The socio-economic costs are not fully recognised. Current research suggests that being overweight or obese and metabolic syndromes such as type 2 diabetes and hypertension are common conditions in patients affected by NAFLD. The prevalence of NAFLD in the general population ranges from 20% to 30% in Europe and will become the leading cause of liver transplantation in the next 10-20 years. These diseases are not a policy or a treatment priority in the EU. Liver disease strategies are missing or are not implemented across Europe. Against this scenario Carlos Moedas, Commissioner for Research and Innovation stressed the "need to scale up efforts in research and innovation [to] develop simple, cost-effective and non-invasive tests" that will allow to "improve guidance to member states on primary care and better management" he continued. "This Summit [is] intended to trigger a serious debate around NAFLD, to increase the policy focus on this imminent public health challenge that Europe is facing," stated Tatjana Reic. "The community needs to take action to establish effective policies for early detection and effective therapies, and put more effort into prevention policies across the European Union." Prof Helena Cortez-Pinto, the EU Counsellor at EASL, reminded MEPs that they had a key role to play in prevention but pointed out that they have just missed a rare opportunity to restrict the marketing of junk food to minors when debating the Audio Visual Media Services Directive. "Childhood obesity is the plague of the 21st century and MEPs could have tightened restrictions on marketing to minors," she said. "Unfortunately they chose not to take this step. They talk the talk but don't walk the walk." We are going to spend billions and billions of Euros in the next decades, trying to cure diseases that might have easily been prevented with simple measures, such as those restrictions. She called on MEPs and the Member States to remedy this in the trialogues on the proposal that will start in June or July. "As Members of the European Parliament we were elected to represent the voice of the European citizens. When it comes to health issues we must therefore speak in one voice with our patients and do everything in our power and position to put NAFLD-NASH challenge in the centre of our policy efforts," MEP Alojz Peterle, stated.


Il vertice è stato organizzato dall'associazione europea dei pazienti epatici (ELPA, European Liver Patients' Association), in collaborazione con l'Associazione Europea per lo Studio del Fegato (EASL, European Association for the Study of the Liver). L'evento si è svolto presso il Parlamento europeo (a Bruxelles) ed è stato ospitato da Alojz Peterle, membro del Parlamento europeo. I partecipanti hanno esplorato le potenziali misure per ridurre il peso della malattia e per mitigare l'impatto che steatosi epatica non alcolica (NAFLD, Non-Alcoholic Fatty Liver Disease) e steatoepatite non alcolica (NASH, non-alcoholic steatohepatitis) avranno sulla sostenibilità dei sistemi sanitari. "La serietà della steatosi epatica non alcolica e il potenziale impatto che avrà sui sistemi sanitari devono essere riconosciuti e affrontati prima di trovarci a far fronte a un'epidemia in tutta l'Europa", ha dichiarato Tatjana Reic, presidente dell'ELPA. La steatosi epatica non alcolica, che è diventato il più comune disturbo epatico cronico in Europa e negli Stati Uniti, e la steatoepatite non alcolica, sono considerati come disturbi dovuti alle condizioni di vita. I costi socio-economici non sono ancora riconosciuti appieno. La ricerca attuale suggerisce che l'essere sovrappeso o obesi e le sindromi metaboliche come il diabete di tipo 2 e l'ipertensione sono disturbi comuni nei pazienti affetti dalla steatosi epatica non alcolica. La prevalenza della steatosi epatica non alcolica nella popolazione generale varia dal 20% al 30% in Europa e diventerà la causa principale di trapianto del fegato entro i prossimi 10-20 anni. Queste malattie non sono una priorità politica o di trattamento nell'UE. Le strategie relative alle malattie epatiche sono mancanti o non attuate in tutta Europa. In questo scenario, Carlos Moedas, Commissario per la ricerca e l'innovazione, ha sottolineato la "necessità di aumentare gli sforzi nella ricerca e nell'innovazione [allo scopo di] sviluppare test semplici, economici e non invasivi" che consentiranno di "migliorare la guida ai paesi membri in materia di cure di base e migliore gestione", ha continuato. "Questo Vertice [è] destinato a scatenare un serio dibattito riguardo alla steatosi epatica non alcolica, per aumentare l'attenzione politica su questo imminente problema di sanità pubblica che l'Europa si trova ad affrontare", ha dichiarato Tatjana Reic. "La comunità deve intervenire per stabilire politiche efficaci per la diagnosi precoce e terapie efficaci, e impegnarsi di più nelle politiche di prevenzione in tutta l'Unione europea". La professoressa Helena Cortez-Pinto, il Consigliere dell'UE presso EASL, ha ricordato agli eurodeputati che si sono trovati con un ruolo fondamentale da svolgere nella prevenzione, ma ha sottolineato che avevano appena perso una rara opportunità di limitare la commercializzazione di alimenti spazzatura ai minori quando è stata discussa la direttiva sui servizi di media audiovisivi. "L'obesità infantile è la peste del ventunesimo secolo e gli eurodeputati avrebbero potuto rafforzare le restrizioni alla commercializzazione ai minori", ha detto. "Purtroppo hanno scelto di non fare questo passo. Parlano bene, ma poi non agiscono di conseguenza". Spenderemo molti miliardi di euro nei prossimi decenni, cercando di curare malattie che avrebbero potuto essere state facilmente oggetto di prevenzione grazie a misure semplici, come quelle restrizioni. Ha invitato gli eurodeputati e i paesi membri a risolvere questo problema durante i triloghi sulla proposta che inizieranno a giugno o luglio. "In qualità di membri del Parlamento europeo siamo stati eletti per rappresentare la voce dei cittadini europei. Per quanto riguarda le questioni sanitarie, dobbiamo quindi parlare in modo unanime con i nostri pazienti e fare tutto quanto in possiamo per mettere la sfida della steatosi epatica non alcolica e della steatoepatite non alcolica al centro dei nostri sforzi politici", ha dichiarato il deputato Alojz Peterle.


Les participants ont exploré les mesures potentielles pour réduire le fardeau de la maladie et pour atténuer l'impact que la NAFLD (maladie du foie gras d'origine non-alcoolique) et la NASH (stéatose hépatique non alcoolique) ont sur la durabilité des systèmes de santé. « La gravité de la NAFLD et l'impact potentiel qu'elle aura sur les systèmes de santé doit être reconnu et affronté avant que nous ne rencontrions une épidémie dans toute l'Europe », a déclaré Tatjana Reic, présidente de l'ELPA. La NAFLD, qui est devenu le trouble hépatique chronique le plus courant en Europe et aux États-Unis, et la NASH sont considérées comme des maladies causées par le style de vie. Les coûts socio-économiques ne sont pas entièrement reconnus. Les recherches actuelles suggèrent que le surpoids ou les syndromes obèses et métaboliques tels que le diabète de type 2 et l'hypertension sont des affections fréquentes chez les patients souffrant de la NAFLD. La prévalence de la NAFLD dans la population générale varie de 20 % à 30 % en Europe et deviendra la principale cause de transplantation hépatique au cours des 10 à 20 ans à venir. Ces maladies ne sont pas une priorité politique ou de traitement dans l'Union européenne. Les stratégies de maladies du foie manquent ou ne sont pas mises en œuvre en Europe. Pour contrer ce scénario, Carlos Moedas, le commissaire chargé de la recherche et de l'innovation a insisté sur le fait qu'il « fallait augmenter les efforts de recherche et d'innovation pour élaborer des tests simples, rentables et non invasifs » qui permettront « d'améliorer les orientations aux États membres sur les soins primaires et la meilleure gestion », a-t-il poursuivi. La professeure Helena Cortez-Pinto, la conseillère auprès de l'UE de l'EASL, a rappelé aux membres du Parlement européen qu'ils ont un rôle clé à jouer dans la prévention, mais elle a fait remarquer qu'ils ont juste manqué une opportunité rare de restreindre le marketing des aliments contenant des calories vides (junk food) aux mineurs lorsqu'ils ont débattu de la directive des services des médias audiovisuels. « L'obésité infantile est la plaie du 21[e] siècle et les membres du Parlement européen pourraient avoir durci le marketing sur les mineurs », a-t-elle dit. « Malheureusement, ils ont choisi de ne pas faire ce pas. Ils ne font pas ce qu'ils disent. » Nous allons dépenser des milliards et des milliards d'euros dans les prochaines décennies pour essayer de soigner des maladies qui pourraient facilement avoir été évitées avec de simples mesures, telles que ces restrictions. Elle a appelé les membres du Parlement européen et les États membres à remédier à cela dans les trilogues sur la proposition qui commencera en juin ou en juillet.


News Article | May 31, 2017
Site: www.prnewswire.com

The Summit was organised by the European Liver Patients' Association, in partnership with the European Association for the Study of the Liver. The event took place in the European Parliament (Brussels) and was hosted by Alojz Peterle, Member of the European Parliament. Participants explored potential measures to reduce the burden of the disease and to mitigate the impact that NAFLD-NASH will have on the sustainability of healthcare systems. "The seriousness of NAFLD and the potential impact it will have on healthcare systems needs to be recognised and addressed before we encounter an epidemic across Europe," stated Tatjana Reic, President of ELPA. NAFLD, which has become the most common chronic liver disorder in Europe and the U.S., and NASH are seen as lifestyle conditions. The socio-economic costs are not fully recognised. Current research suggests that being overweight or obese and metabolic syndromes such as type 2 diabetes and hypertension are common conditions in patients affected by NAFLD. The prevalence of NAFLD in the general population ranges from 20% to 30% in Europe and will become the leading cause of liver transplantation in the next 10-20 years. These diseases are not a policy or a treatment priority in the EU. Liver disease strategies are missing or are not implemented across Europe. Against this scenario Carlos Moedas, Commissioner for Research and Innovation stressed the "need to scale up efforts in research and innovation [to] develop simple, cost-effective and non-invasive tests" that will allow to "improve guidance to member states on primary care and better management" he continued. "This Summit [is] intended to trigger a serious debate around NAFLD, to increase the policy focus on this imminent public health challenge that Europe is facing," stated Tatjana Reic. "The community needs to take action to establish effective policies for early detection and effective therapies, and put more effort into prevention policies across the European Union." Prof Helena Cortez-Pinto, the EU Counsellor at EASL, reminded MEPs that they had a key role to play in prevention but pointed out that they have just missed a rare opportunity to restrict the marketing of junk food to minors when debating the Audio Visual Media Services Directive. "Childhood obesity is the plague of the 21st century and MEPs could have tightened restrictions on marketing to minors," she said. "Unfortunately they chose not to take this step. They talk the talk but don't walk the walk." We are going to spend billions and billions of Euros in the next decades, trying to cure diseases that might have easily been prevented with simple measures, such as those restrictions. She called on MEPs and the Member States to remedy this in the trialogues on the proposal that will start in June or July. "As Members of the European Parliament we were elected to represent the voice of the European citizens. When it comes to health issues we must therefore speak in one voice with our patients and do everything in our power and position to put NAFLD-NASH challenge in the centre of our policy efforts," MEP Alojz Peterle, stated.


Das Gipfeltreffen wurde von der europäischen Vereinigung von Leberpatienten ELPA (European Liver Patient Association) in Partnerschaft mit der EASL (European Association for the Study of the Liver) organisiert. Die Konferenz wurde im Europaparlament in Brüssel abgehalten. Gastgeber war Europaparlamentsabgeordneter Alojz Peterle. NAFLD (inzwischen die verbreitetste chronische Lebererkrankung in Europa und den USA) und NASH gelten als Zivilisationskrankheiten. Die sozioökonomischen Kosten sind noch nicht vollkommen klar. Neuere Forschungsergebnisse haben ergeben, dass NAFLD-Patienten häufig übergewichtig oder adipös sind und unter metabolischen Syndromen wie Diabetes Typ 2 und Bluthochdruck leiden. NAFLD tritt bei 20 bis 30 % der Gesamtbevölkerung in Europa auf und wird sich in den nächsten 10 bis 20 Jahren zur Hauptursache für Lebertransplantationen entwickeln. Für diese Erkrankungen gibt es bisher in der EU noch keine Richtlinien oder Behandlungspriorität. Strategien für Lebererkrankungen sind überall in Europa entweder nicht vorhanden oder werden nicht implementiert. In Anbetracht dieser Tatsachen betonte Carlos Moedas, EU-Kommissar für Forschung, Wissenschaft und Innovation, wie wichtig es sei, die "Forschungs- und Innovationsanstrengungen zur Entwicklung eines einfachen, kostengünstigen und nichtinvasiven Tests zu verstärken", um den "Mitgliedstaaten bessere Richtlinien zur Primärversorgung und wirksameren Behandlung zu bieten". Prof. Helena Cortez-Pinto, EU-Beraterin des EASL, erinnerte die Europaparlamentsabgeordneten an ihre wichtige Rolle bei der Vorbeugung. Sie wies jedoch darauf hin, dass das Parlament bei der Debatte der Richtlinie über audiovisuelle Mediendienste (AVMD-Richtlinie) die seltene Gelegenheit verpasst habe, die Vermarktung von Junkfood an Minderjährige zu reduzieren. "Adipositas unter Kindern ist die Seuche des 21. Jahrhunderts, und die Parlamentsmitglieder hätten die Vermarktung an Minderjährige einschränken können", sagt sie. "Leider haben sie sich gegen diesen Schritt entschieden. Sie sprechen darüber, lassen ihren Worten jedoch keine Taten folgen." Wir werden in den kommenden Jahrzehnten Milliarden und Abermilliarden von Euro zur Behandlung von Krankheiten ausgeben müssen, die sich durch einfache Maßnahmen, wie z. B. solche Marketingeinschränkungen, hätten verhindern lassen. Sie rief die Abgeordneten und Mitgliedstaaten dazu auf, dies in den Dreiergesprächen zum Vorschlag zu korrigieren, die im Juni oder Juli beginnen werden.


Fetisov L.Y.,Moscow State University | Chashin D.V.,Moscow State University | Fetisov Y.K.,Moscow State University | Segalla A.G.,ELPA Company | Srinivasan G.,Oakland University
Journal of Applied Physics | Year: 2012

A novel three-layer composite consisting of a lead zirconate titanate (PZT) substrate, a PZT film on one side, and a film of ferromagnetic alloy on the other side is fabricated and used for studies on the nature of magneto-electric (ME) interactions. The strain mediated ME voltage under an ac magnetic excitation is compared with the voltage produced by pure piezoelectric response of the sample to an ac electric field. The ME voltage response measured across PZT substrate or PZT film under an ac magnetic field shows peaks at bending modes and longitudinal acoustic modes, with a higher voltage at bending mode than for the longitudinal acoustic mode. A variation in the bending mode frequency with bias magnetic field or electric field is observed and is attributed to variation in the Young's modulus of the magnetic or piezoelectric layers. Estimates of resonance frequencies and ME coefficients are in agreement with the data. Under an ac electric excitation, piezoelectric effects result in a resonance in the voltage measured across the PZT substrate and film. A quantitative agreement is inferred between the measured ME voltage and the voltage produced under an ac electric field. © 2012 American Institute of Physics.


Fetisov Y.K.,RAS Institute of Radio Engineering and Electronics | Chashin D.V.,RAS Institute of Radio Engineering and Electronics | Segalla A.G.,ELPA Company | Srinivasan G.,Oakland University
Journal of Applied Physics | Year: 2011

Studies in recent years have focused mainly on strain mediated magnetoelectric (ME) effects in magnetostrictive-piezoelectric composites. This report is on resonance ME effects in a piezoelectric bimorph. The effect arises due to combination of piezoelectricity and the Ampere force on the sample that carries an ac electric current and placed in a bias magnetic field. The ME coefficient is as high as 16.5 V/(A kOe) at 153 Hz due to bending oscillations. Estimated ME coefficients are in agreement with the data. © 2011 American Institute of Physics.


Politova E.D.,Karpov Institute of Physical Chemistry | Akinfiev V.S.,Moscow State University | Kaleva G.M.,Karpov Institute of Physical Chemistry | Mosunov A.V.,Karpov Institute of Physical Chemistry | And 2 more authors.
Ferroelectrics | Year: 2014

The effect of the KCl additives with low melting temperature (∼1050 K), on the structural, dielectric and polar properties of 0.36BiScO3 - 0.64PbTiO3 ceramics was studied. The ceramics doped by the KCl additives were prepared by the solid state reaction method. Phase formation, polar and dielectric properties of modified ceramics were studied. Dense single phase samples doped by the KCl additives were obtained at lower temperatures in comparison with that of undoped samples. Influence of additives on dielectric properties was revealed.


Golubko N.V.,Karpov Institute of Physical Chemistry | Kaleva G.M.,Karpov Institute of Physical Chemistry | Mosunov A.V.,Karpov Institute of Physical Chemistry | Politova E.D.,Karpov Institute of Physical Chemistry | Segalla A.H.,ELPA Company
IOP Conference Series: Materials Science and Engineering | Year: 2016

Influence of the NaCl/LiF additives (with ratio 60:40) on structure parameters, phase transitions and dielectric properties of solid solutions close to the Morphotropic Phase Boundary in the system (1-x)BiScO3 - xPbTiO3 (x=0.635, 0.645) has been studied. Using as initial the BSPT powders prepared from nitrate solutions, dense single phase ceramic samples doped by 5, 10 and 15 w. % of NaCl/LiF have been prepared at 1313 - 1323 K (2 h). Shift of the BSPT compositions phase content from initial mixtures of Rhombohedral and Tetragonal phases to the region of Tetragonal phase was stimulated by addition of the NaCl/LiF additives. This effect is accompanied by decrease of the unit sell volume, increase in the c/a ratio and increase in the Curie temperature value from 668 to 730 K for x=0.635 and from 672 to 724 K for x=0.645 in compositions doped by 10 w. % of the NaCl/LiF additive. © Published under licence by IOP Publishing Ltd.


Anisimkin V.I.,Russian Academy of Sciences | Pyataikin I.I.,Russian Academy of Sciences | Voronova N.V.,Elpa Corporation
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control | Year: 2012

The Anisimkin Jr. (AN) acoustic plate mode having dominant and depth-independent longitudinal displacement (u1 u2, u3; u1 constant) is numerically found in tetragonal 4mm Li2B4O7 crystal with one of the low-symmetry orientations (Euler angles 89, 37, 104), as an example. The quasi-longitudinal (QL) modes with dominant and depth-dependent longitudinal displacement (u1 u2, u3; u1 constant) are experimentally detected along several propagation directions in 128y-LiNbO3 plate, where = 0, 30, 60, and 90 with respect to the x-axis. Compared with more symmetrical plate materials and orientations, the displacement profiles of the AN and QL modes in lower-symmetry counterparts are qualitatively the same, but their phase profiles are more complicated. Moreover, like any acoustic wave, all plate modes in anisotropic crystals suffer from beam steering, in general. The power flow angles of the modes propagating in a fixed direction are different and depend on the mode order n. © 2012 IEEE.

Loading ELPA Company collaborators
Loading ELPA Company collaborators