Matsuyama, Japan
Matsuyama, Japan

Ehime University is a Japanese national university in Matsuyama, Ehime, Japan. The university has one of the largest student populations in the Shikoku region.After Japan's defeat in World War II, Aidai was established in May 1949 among many other national universities by the Japanese government during the reformation of the education system. The university originally had three Faculties : Humanities and Science, Education, and Engineering; which were consolidated from Matsuyama National High School , Ehime Prefectural Teachers School , Ehime Prefectural Youth Teachers School , and Ehime Prefectural Niihama Technical School .Today, the university has six faculties and five graduate schools. Wikipedia.


Time filter

Source Type

Patent
Fujitsu Limited and Ehime University | Date: 2016-05-19

An evaluation method includes: collecting pieces of data of travel speeds corresponding to positions included in a specific area for each of a first vehicle group and a second vehicle group, based on a piece of data of a travel speed corresponding to a position of each of vehicles included in the first vehicle group and a piece of data of a travel speed corresponding to a position of each of vehicles included in the second vehicle group, by a processor; and evaluating the specific area based on a result of comparison between a tendency of values indicated by the pieces of the data of the travel speeds collected for the first vehicle group and a tendency of values indicated by the pieces of the data of the travel speeds collected for the second vehicle group, by the processor.


Patent
Ehime University, Shiga University of Medical Science and Yokohama City University | Date: 2015-11-04

Provided in the present invention is a genetic marker including a SNP which can be used for assessing the risk of developing hypertension, a polynucleotide for assessing the risk of developing hypertension which can be used as a primer or probe for detecting the genetic marker, a method for assessing the risk of developing hypertension using the SNP, a microarray for assessing the risk of developing hypertension which is used for genotyping of the SNP, a kit used in the method for assessing the risk of developing hypertension, and the like.


Patent
Ehime University, Shiga University of Medical Science and Yokohama City University | Date: 2015-10-28

Provided in the present invention is a genetic marker including a SNP which can be used for assessing the risk of developing hypertension, a polynucleotide for assessing the risk of developing hypertension which can be used as a primer or probe for detecting the genetic marker, a method for assessing the risk of developing hypertension using the SNP, a microarray for assessing the risk of developing hypertension which is used for genotyping of the SNP, a kit used in the method for assessing the risk of developing hypertension, and the like.


Kamao T.,Ehime University
American journal of ophthalmology | Year: 2011

To evaluate the newly developed Ocular Surface Thermographer (TOMEY Corporation) for dry eye screening. Prospective, controlled study. We studied 30 eyes of 30 patients diagnosed with dry eye (mean age ± standard deviation, 52.9 ± 17.1 years) and 30 eyes of 30 normal subjects (42.7 ± 17.0 years). The ocular surface temperature was measured immediately after eye opening and every second during 10 seconds of eye opening. The reliability of the measurements was determined by calculating intraclass correlation coefficients. Then, the correlations between the change in the ocular surface temperature and tear film break-up time, Schirmer I test values, and fluorescein staining scores were determined. The measurements of the ocular surface temperature had a high degree of reliability. Immediately after eye opening, the temperature in the dry eye did not differ significantly from that in normal eyes in any of the 3 regions tested. The decrease in the ocular surface temperature in dry eyes was significantly greater than that in normal eyes (P < .001) at 10 seconds after eye opening. The decrease in the temperature of the cornea was correlated significantly with the tear film break-up time (r = -0.572; P < .001). When the changes in ocular surface temperature of the cornea were used as an index for dry eye, the sensitivity was 0.83 and the specificity was 0.80 after 10 seconds. Measurements of the ocular surface temperature obtained with our newly developed Ocular Surface Thermographer after 10 seconds of eye opening may provide a simple, noninvasive screening test for dry eyes. Copyright © 2011 Elsevier Inc. All rights reserved.


Riboswitches are RNA elements in mRNA that control gene expression in cis in response to their specific ligands. Because artificial riboswitches make it possible to regulate any gene with an arbitrary molecule, they are expected to function as biosensors, in which the output is easily detectable protein expression. I report herein a fully rational design strategy for artificially constructing novel riboswitches that work in a eukaryotic cell-free translation system (wheat germ extract). In these riboswitches, translation mediated by an internal ribosome entry site (IRES) is promoted only in the presence of a specific ligand (ON), while it is inhibited in the absence of the ligand (OFF). The first rationally designed riboswitch, which is regulated by theophylline, showed a high switching efficiency and dependency on theophylline. In addition, based on the design of the theophylline-dependent riboswitch, other three kinds of riboswitches controlled by FMN, tetracycline, and sulforhodamine B, were constructed only by calculating the ΔG value of one stem - loop structure. The rational design strategy described herein is therefore useful for easily producing various ligand-dependent riboswitches, which are available as biosensors for detecting their ligands. Published by Cold Spring Harbor Laboratory Press. Copyright © 2011 RNA Society.


First principles calculations have shown that the high-pressure phase transition of phase D MgSi2O6H2 to the new high-pressure hydrous phase MgSiO4H2 plus stishovite occurs at about 40 GPa. The crystal structure of the new phase is very similar to that of CaCl2-type SiO2 and has monoclinic symmetry with space group P2/m. This new hydrous phase is stable up to about 52 GPa and then dissociates into MgSiO3 perovskite and H2O (ice VIII) at static 0 K conditions. The Clapeyron slope between phase D and the new phase + SiO2 is positive; about 6.4 MPa/K at 1000 K. This new hydrous phase further extends the stability field of dense hydrous magnesium silicates and also opens the pathway toward the existence of a high-pressure phase of ice at the lower mantle conditions. Key Points High pressure phase of phase D has been predicted This new phase dissociate into PV and H2O at higher pressure conditions There is a possibility of the existence of high pressure ice in the Earth ©2013. American Geophysical Union. All Rights Reserved.


Although epidemiological studies in the US and Europe have confirmed that type 2 diabetes mellitus (DM) is associated with an increased risk of cardiovascular disease (CVD) events, evidence is limited in Japan. Earlier studies in Japan showed that hypertension has a major effect on atherosclerosis in relatively lean subjects, with type 2 DM contributing more to CVD events, because of a decline in blood pressure levels in both sexes and an increase in body mass index in men. Recent cohort studies in Japan using baseline assessments carried out during the 1990 s have confirmed that type 2 DM is associated with an increased risk of coronary heart disease (CHD) and all types of stroke, except hemorrhagic stroke. In addition, the metabolic syndrome, a constellation of metabolic risk factors, was shown to predict CVD events in Japanese people, independent of the presence or absence of obesity. The strong association of type 2 DM with CHD (hazard ratio: 1.5-4) and ischemic stroke (hazard ratio: 2-4) events was confirmed in Japanese adults. Individuals with impaired glucose tolerance or impaired fasting glucose were also shown to have an increased risk of a CHD event, but not a stroke.


Hori H.,Ehime University
Frontiers in Genetics | Year: 2014

To date, more than 90 modified nucleosides have been found in tRNA and the biosynthetic pathways of the majority of tRNA modifications include a methylation step(s). Recent studies of the biosynthetic pathways have demonstrated that the availability of methyl group donors for the methylation in tRNA is important for correct and efficient protein synthesis. In this review, I focus on the methylated nucleosides and tRNA methyltransferases. The primary functions of tRNA methylations are linked to the different steps of protein synthesis, such as the stabilization of tRNA structure, reinforcement of the codon-anticodon interaction, regulation of wobble base pairing, and prevention of frameshift errors. However, beyond these basic functions, recent studies have demonstrated that tRNA methylations are also involved in the RNA quality control system and regulation of tRNA localization in the cell. In a thermophilic eubacterium, tRNA modifications and the modification enzymes form a network that responses to temperature changes. Furthermore, several modifications are involved in genetic diseases, infections, and the immune response. Moreover, structural, biochemical, and bioinformatics studies of tRNA methyltransferases have been clarifying the details of tRNA methyltransferases and have enabled these enzymes to be classified. In the final section, the evolution of modification enzymes is discussed. © 2014 Hori.


Kusuhashi N.,Ehime University
Proceedings. Biological sciences / The Royal Society | Year: 2013

We here describe a new Early Cretaceous (early Albian) eutherian mammal, Sasayamamylos kawaii gen. et sp. nov., from the 'Lower Formation' of the Sasayama Group, Hyogo Prefecture, Japan. Sasayamamylos kawaii is characterized by a robust dentary, a distinct angle on the ventral margin of the dentary at the posterior end of the mandibular symphysis, a lower dental formula of 3-4 : 1 : 4 : 3, a robust lower canine, a non-molariform lower ultimate premolar, and a secondarily reduced entoconid on the molars. To date, S. kawaii is the earliest known eutherian mammal possessing only four premolars, which demonstrates that the reduction in the premolar count in eutherians started in the late Early Cretaceous. The occurrence of S. kawaii implies that the relatively rapid diversification of eutherians in the mid-Cretaceous had already started by the early Albian.


A nanometer-size-particle production apparatus is provided which can prevent the occurrence of waste fluids, and which makes quick and continuous syntheses feasible while suppressing damages to the electrode. The present invention is a nanometer-size-particle production apparatus for synthesizing nanometer-size particles in a liquid by means of plasma in liquid, and comprises: a container for accommodating the liquid therein; an electromagnetic-wave generation device for generating a high-frequency wave, or a microwave; an electrode conductor whose leading end makes contact with the liquid to supply the high-frequency wave or the microwave to the liquid; a covering portion being disposed into the liquid so as to cover a leading-end upside of the electrode conductor; a metallic chip being composed of a metal making a raw material of nanometer-size particles, and having a leading end that is disposed to face to a leading-end section of the electrode conductor; and a feed device for feeding out the leading end of the metallic chip with respect to the leading-end section of the electrode conductor; the leading end of the electrode conductor having a configuration that is a non-edge configuration; and the electrode conductor, except for the leading end, having an axially-orthogonal cross-sectional area that is larger than an axially-orthogonal cross-sectional area of the metallic chip.

Loading Ehime University collaborators
Loading Ehime University collaborators