Ehime University is a Japanese national university in Matsuyama, Ehime, Japan. The university has one of the largest student populations in the Shikoku region.After Japan's defeat in World War II, Aidai was established in May 1949 among many other national universities by the Japanese government during the reformation of the education system. The university originally had three Faculties : Humanities and Science, Education, and Engineering; which were consolidated from Matsuyama National High School , Ehime Prefectural Teachers School , Ehime Prefectural Youth Teachers School , and Ehime Prefectural Niihama Technical School .Today, the university has six faculties and five graduate schools. Wikipedia.
Fujifilm Co. and Ehime University | Date: 2015-07-10
An analysis method is provided that ensures objective and quantitative analysis for analyzing time-series images. For implementing the method are provided an image data storage unit that stores therein image data on a plurality of time-series computed tomography (CT) images of an organ of a subject captured after a contrast medium has been administered; a target pixel extraction unit configured to extract an intra-organ pixel position, which is a position of a pixel in a region of the organ; a change-over-time determining unit configured to determine a change-over-time of a CT value of the pixel at the determined intra-organ pixel position, based on image data on the time series CT images in the plurality of frames; and a function approximation processing unit configured to determine an arrival time at which the contrast medium has arrived at an organ at the intra-organ pixel position and a base value, which is a CT value serving as a base of the pixel at the intra-organ pixel position, based on the determined change-over-time.
Ehime University | Date: 2015-06-24
The present invention provides an artificial knee joint that can reconstruct an anterior cruciate ligament in a state close to an original function. An artificial knee joint (1) that is used in a total knee replacement includes a femur member (10) and a tibia member (20). The tibia member (20) has a ligament insertion hole (20h) which pierces the tibia member (20) and which is formed at a position where once an anterior cruciate ligament (ACL) exists in a knee replaced for the artificial knee joint (1). Therefore, a ligament can be provided such that a distal end (DT) of a femur (F) and a proximal end (PE) of a tibia (T) are joined to each other by passing the ligament through the ligament insertion hole (20h), which allows the anterior cruciate ligament (ACL) to be reconstructed so as to be in the substantially same state as a knee replaced for the artificial knee joint (1).
Fujifilm Co. and Ehime University | Date: 2017-05-24
An analysis method is provided that ensures objective and quantitative analysis for analyzing time-series images. For implementing the method, are provided an image data storage unit 11 that stores therein image data on a plurality of time-series computed tomography (CT) images of an organ of a subject captured after a contrast medium has been administered; a target pixel extraction unit 31 configured to extract an intra-organ pixel position, which is a position of a pixel in a region of the organ; a change-over-time determining unit 33 configured to determine a change-over-time of a CT value of the pixel at the determined intra-organ pixel position, based on image data on the time series CT images in the plurality of frames; and a function approximation processing unit 37 configured to determine an arrival time at which the contrast medium has arrived at an organ at the intra-organ pixel position and a base value, which is a CT value serving as a base of the pixel at the intra-organ pixel position, based on the determined change-over-time.
Ehime University | Date: 2015-03-31
Disclosed herein is a functional material having the function of detecting a predetermined substance or the like present in a sample with high accuracy even when the amount of the sample is small, and a method for producing the functional material. The functional material includes a channel part 10 that allows a liquid to pass therethrough, and the channel part 10 is made of a water-permeable material 11 containing a water-impermeable material 12. The water-impermeable material 12 is placed between pieces of the water-permeable material 11, and therefore voids 10h can be formed between the water-impermeable material 12 and the water-permeable material 11. That is, a network of the voids 10h can be formed in the channel part 10. A liquid sample supplied to the channel part 10 is allowed to move while being allowed to penetrate into the voids 10h. In addition, components other than a desired component can be separated and removed from a mixture present in the liquid sample while the liquid sample is allowed to move. Therefore, a water-absorbing function and a filtering function can be imparted to the channel part 10.
Fujitsu Limited and Ehime University | Date: 2016-05-19
An evaluation method includes: collecting pieces of data of travel speeds corresponding to positions included in a specific area for each of a first vehicle group and a second vehicle group, based on a piece of data of a travel speed corresponding to a position of each of vehicles included in the first vehicle group and a piece of data of a travel speed corresponding to a position of each of vehicles included in the second vehicle group, by a processor; and evaluating the specific area based on a result of comparison between a tendency of values indicated by the pieces of the data of the travel speeds collected for the first vehicle group and a tendency of values indicated by the pieces of the data of the travel speeds collected for the second vehicle group, by the processor.
Kamao T.,Ehime University
American journal of ophthalmology | Year: 2011
To evaluate the newly developed Ocular Surface Thermographer (TOMEY Corporation) for dry eye screening. Prospective, controlled study. We studied 30 eyes of 30 patients diagnosed with dry eye (mean age ± standard deviation, 52.9 ± 17.1 years) and 30 eyes of 30 normal subjects (42.7 ± 17.0 years). The ocular surface temperature was measured immediately after eye opening and every second during 10 seconds of eye opening. The reliability of the measurements was determined by calculating intraclass correlation coefficients. Then, the correlations between the change in the ocular surface temperature and tear film break-up time, Schirmer I test values, and fluorescein staining scores were determined. The measurements of the ocular surface temperature had a high degree of reliability. Immediately after eye opening, the temperature in the dry eye did not differ significantly from that in normal eyes in any of the 3 regions tested. The decrease in the ocular surface temperature in dry eyes was significantly greater than that in normal eyes (P < .001) at 10 seconds after eye opening. The decrease in the temperature of the cornea was correlated significantly with the tear film break-up time (r = -0.572; P < .001). When the changes in ocular surface temperature of the cornea were used as an index for dry eye, the sensitivity was 0.83 and the specificity was 0.80 after 10 seconds. Measurements of the ocular surface temperature obtained with our newly developed Ocular Surface Thermographer after 10 seconds of eye opening may provide a simple, noninvasive screening test for dry eyes. Copyright © 2011 Elsevier Inc. All rights reserved.
Ogawa A.,Ehime University
RNA | Year: 2011
Riboswitches are RNA elements in mRNA that control gene expression in cis in response to their specific ligands. Because artificial riboswitches make it possible to regulate any gene with an arbitrary molecule, they are expected to function as biosensors, in which the output is easily detectable protein expression. I report herein a fully rational design strategy for artificially constructing novel riboswitches that work in a eukaryotic cell-free translation system (wheat germ extract). In these riboswitches, translation mediated by an internal ribosome entry site (IRES) is promoted only in the presence of a specific ligand (ON), while it is inhibited in the absence of the ligand (OFF). The first rationally designed riboswitch, which is regulated by theophylline, showed a high switching efficiency and dependency on theophylline. In addition, based on the design of the theophylline-dependent riboswitch, other three kinds of riboswitches controlled by FMN, tetracycline, and sulforhodamine B, were constructed only by calculating the ΔG value of one stem - loop structure. The rational design strategy described herein is therefore useful for easily producing various ligand-dependent riboswitches, which are available as biosensors for detecting their ligands. Published by Cold Spring Harbor Laboratory Press. Copyright © 2011 RNA Society.
Saito I.,Ehime University
Circulation Journal | Year: 2012
Although epidemiological studies in the US and Europe have confirmed that type 2 diabetes mellitus (DM) is associated with an increased risk of cardiovascular disease (CVD) events, evidence is limited in Japan. Earlier studies in Japan showed that hypertension has a major effect on atherosclerosis in relatively lean subjects, with type 2 DM contributing more to CVD events, because of a decline in blood pressure levels in both sexes and an increase in body mass index in men. Recent cohort studies in Japan using baseline assessments carried out during the 1990 s have confirmed that type 2 DM is associated with an increased risk of coronary heart disease (CHD) and all types of stroke, except hemorrhagic stroke. In addition, the metabolic syndrome, a constellation of metabolic risk factors, was shown to predict CVD events in Japanese people, independent of the presence or absence of obesity. The strong association of type 2 DM with CHD (hazard ratio: 1.5-4) and ischemic stroke (hazard ratio: 2-4) events was confirmed in Japanese adults. Individuals with impaired glucose tolerance or impaired fasting glucose were also shown to have an increased risk of a CHD event, but not a stroke.
Kusuhashi N.,Ehime University
Proceedings. Biological sciences / The Royal Society | Year: 2013
We here describe a new Early Cretaceous (early Albian) eutherian mammal, Sasayamamylos kawaii gen. et sp. nov., from the 'Lower Formation' of the Sasayama Group, Hyogo Prefecture, Japan. Sasayamamylos kawaii is characterized by a robust dentary, a distinct angle on the ventral margin of the dentary at the posterior end of the mandibular symphysis, a lower dental formula of 3-4 : 1 : 4 : 3, a robust lower canine, a non-molariform lower ultimate premolar, and a secondarily reduced entoconid on the molars. To date, S. kawaii is the earliest known eutherian mammal possessing only four premolars, which demonstrates that the reduction in the premolar count in eutherians started in the late Early Cretaceous. The occurrence of S. kawaii implies that the relatively rapid diversification of eutherians in the mid-Cretaceous had already started by the early Albian.
Ehime University | Date: 2016-02-22
A nanometer-size-particle production apparatus is provided which can prevent the occurrence of waste fluids, and which makes quick and continuous syntheses feasible while suppressing damages to the electrode. The present invention is a nanometer-size-particle production apparatus for synthesizing nanometer-size particles in a liquid by means of plasma in liquid, and comprises: a container for accommodating the liquid therein; an electromagnetic-wave generation device for generating a high-frequency wave, or a microwave; an electrode conductor whose leading end makes contact with the liquid to supply the high-frequency wave or the microwave to the liquid; a covering portion being disposed into the liquid so as to cover a leading-end upside of the electrode conductor; a metallic chip being composed of a metal making a raw material of nanometer-size particles, and having a leading end that is disposed to face to a leading-end section of the electrode conductor; and a feed device for feeding out the leading end of the metallic chip with respect to the leading-end section of the electrode conductor; the leading end of the electrode conductor having a configuration that is a non-edge configuration; and the electrode conductor, except for the leading end, having an axially-orthogonal cross-sectional area that is larger than an axially-orthogonal cross-sectional area of the metallic chip.