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Shanghai, China

East China Normal University , commonly referred to as ECNU, is a comprehensive research university in Shanghai, China. Established in 1951, it is the first national normal university of the People's Republic of China.Originally founded to train school teachers, the University is now an institution training researchers, professors, high-level civil servants, as well as business and political leaders. Sponsored by the national program "Project 211" and "Project 985", the university is a staunch force in the nation's research in the humanities, social science and technology innovation, and is reputed to be the "Columbia of the East". ECNU is ranked 67th in Asia according to the Times Higher Education Asia University Rankings in 2014, while the Leiden Ranking considered it 280th worldwide in 2013.ECNU is an institution of higher education with global impact. China's first Sino-US higher education institute – New York University Shanghai – is jointly operated by New York University and ECNU. King's College London, the University of California, as well as the University of Manchester hold their international summer schools at ECNU each year.Since 2013, the University officially changed its French name to École normale supérieure de l'Est de la Chine, to put forward the academic cooperation between ECNU and the École Normale Supérieure Group in France. And the ENS-ECNU Joint Graduate School was formally established in June 2005. Wikipedia.

Yu S.,CAS Shanghai Institute of Organic Chemistry | Ma S.,CAS Shanghai Institute of Organic Chemistry | Ma S.,East China Normal University
Angewandte Chemie - International Edition | Year: 2012

Allenes are the simplest class of cumulenes, with two contiguous C=C bonds, and show unique physical and chemical properties. These features make allenes particularly attractive in modern organic chemistry. In this Review, attention is paid to the advances made in catalytic asymmetric synthesis and natural product syntheses based on well-established reactions of allenes, such as propargylation, addition, cycloaddition, cycloisomerization, cyclization, etc., with or without catalysts. Their versatile reactivity, substituent-loading ability, axial to center chirality transfer, and controllable selectivity allow access to target molecules by unique and efficient approaches. The main topics in this Review are presented with selected examples from 2003 to 2011. Creative and easy syntheses of chiral compounds and natural products are possible by using allenes. These compounds display exceptional physical and chemical properties, and thus offer new possibilities in catalytic asymmetric synthesis and the total synthesis of natural products. The remarkable progress made in these two topics is summarized selectively in this Review. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Zhao X.,East China Normal University
Topics in Current Chemistry | Year: 2012

Membrane proteins are a large, diverse group of proteins, representing about 20-30% of the proteomes of most organisms, serving a multitude of cellular functions and more than 40% of drug targets. Knowledge of a membrane protein structure enables us insight into its function and dynamics, and can be used for further rational drug design. Owing to the intrinsic hydrophobicity, flexibility, and instability of membrane proteins, solid-state NMR may offer an unique opportunity to study membrane protein structure, ligand binding, and activation at atomic resolution in the native membrane environment on a wide ranging time scale. Over the past several years, solid-state NMR has made tremendous progress, showing its capability of determining membrane protein structure, ligand binding, and protein dynamic conformation on a variety of time scales at atomic resolution. In this chapter we will mainly discuss some recent achievements on membrane protein structure determination, ligand conformation and binding, structure changes upon activation, and structure of insoluble fibrous proteins investigated by using magic-angle spinning solid-state NMR from the structural biology point of view. Protein dynamics, sensitivity enhancement, and the possibility of chemical shift-based structure determination in solid-state NMR are also briefly touched upon. © 2011 Springer-Verlag Berlin Heidelberg.

Zhang C.,Peking University | Tang C.,Peking University | Jiao N.,Peking University | Jiao N.,East China Normal University
Chemical Society Reviews | Year: 2012

Copper salts have been developed as versatile catalysts for oxidative coupling reactions in organic synthesis. During these processes, Cu-catalysts are often proposed to serve as a one-electron oxidant to promote the single-electron transfer process. Recently, the transition-metal catalyzed direct dehydrogenative transformation has attracted considerable attention. This tutorial review summarizes the recent advances in the copper-catalyzed dehydrogenative functionalization via a single electron transfer (SET) process achieving C-C, C-N, C-O, C-halogen atoms, C-P, and N-N bond formation. © The Royal Society of Chemistry 2012.

Wang T.,East China Normal University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2011

The spherically symmetric static solutions are searched for in some f(T) models of gravity theory with a Maxwell term. To do this, we demonstrate that reconstructing the Lagrangian of f(T) theories is sensitive to the choice of frame, and then we introduce a particular frame based on the conformally Cartesian coordinates. In this particular frame, the existence conditions of various solutions are presented. Our results imply that only a limited class of f(T) models can be solved in this frame. For more general models, the search for spherically symmetric static solutions is still an open and challenging problem, hopefully solvable in other frames. © 2011 American Physical Society.

Wang T.,East China Normal University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2010

Two-field slow-roll inflation is the most conservative modification of a single-field model. The main motivations to study it are its entropic mode and non-Gaussianity. Several years ago, for a two-field model with additive separable potentials, Vernizzi and Wands invented an analytic method to estimate its non-Gaussianities. Later on, Choi et al. applied this method to the model with multiplicative separable potentials. In this note, we design a larger class of models whose non-Gaussianity can be estimated by the same method. Under some simplistic assumptions, roughly these models are unlikely able to generate a large non-Gaussianity. We look over some specific models of this class by scanning the full parameter space, but still no large non-Gaussianity appears in the slow-roll region. These models and scanning techniques would be useful for a future model hunt if observational evidence shows up for two-field inflation. © 2010 The American Physical Society.

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