Durham, United Kingdom

Durham University

www.dur.ac.uk
Durham, United Kingdom

Durham University is a collegiate research university in Durham, North East England. It was founded by Act of Parliament in 1832 and granted a Royal Charter in 1837. It was one of the first universities to commence tuition in England for more than 600 years and has claim to be the third oldest university in England.Durham University has a unique estate, which includes 63 listed buildings, ranging from the 11th-century Castle to a 1930s Art Deco Chapel. The university also owns and manages the World Heritage Site in partnership with Durham Cathedral. The university's ownership of the World Heritage Site includes Durham Castle , Palace Green, and the surrounding buildings including the historic Cosin's Library.As a collegiate university, its main functions are divided between the academic departments of the university and 16 colleges. In general, the departments perform research and provide lectures to students, while the colleges are responsible for the domestic arrangements and welfare of undergraduate students, graduate students, post-doctoral researchers and some university staff.The university is currently ranked 5th to 8th by all the latest league tables of the British universities. "Long established as the leading alternative to Oxford and Cambridge", the university attracts "a largely middle class student body" according to The Times's Good University Guide. Durham has the second highest proportion of privately educated students as well as the best quality of student life in the country according to the Lloyds Bank rankings. The university was named Sunday Times University of the Year in 2005, having previously been shortlisted for the award in 2004.Current academics include 15 Fellows of the Royal Society, 18 Fellows of the British Academy, 16 Fellows of the Academy of Social science, 2 Fellows of the Royal Academy of Engineering and 2 Fellows of the Academy of Medical science.The university is a member of the Russell Group of UK universities after previously being a member of the 1994 Group. Durham is also affiliated with several university groups including the N8 Research Partnership and the Matariki Network of Universities.The chancellor of the university is Sir Thomas Allen, who succeeded Bill Bryson in January 2012. The post-nominal letters of graduates have Dunelm attached to indicate the university. Wikipedia.

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Patent
Durham University | Date: 2015-05-28

A method for preparing a cyclic peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to cyclise the peptide, derivative or analogue thereof.


Patent
Durham University | Date: 2015-04-28

A method and apparatus for electrochemical etching are disclosed. The method comprises immersing parts of objects (2) to be etched in an electrolyte (4), applying a voltage between the objects (2) and at least one electrode (6) to cause an electrochemical reaction between the objects (2) and the electrolyte (4), and positioning the objects (2) and electrodes (6) relative to each other such that a reaction product accumulates on the objects (2) during the reaction to reduce the rate of the reaction.


Patent
Durham University | Date: 2017-04-05

A method for preparing a cyclic peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to cyclise the peptide, derivative or analogue thereof.


Patent
Durham University | Date: 2016-11-22

The invention provides a micro-organ composite which comprises a core group of cells and an outer layer of cells, wherein the cells of the core group are mesenchymal cells and the cells of the outer layer are epithelial cells or wherein the cells of the core group are epithelial cells and the cells of the outer layer are mesenchymal cells, and wherein the core group of cells is at least partially encapsulated by the outer layer of cells.


Patent
Durham University | Date: 2015-05-28

A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.


Patent
Durham University | Date: 2017-03-22

A method and apparatus for electrochemical etching are disclosed. The method comprises immersing parts of objects (2) to be etched in an electrolyte (4), applying a voltage between the objects (2) and at least one electrode (6) to cause an electrochemical reaction between the objects (2) and the electrolyte (4), and positioning the objects (2) and electrodes (6) relative to each other such that a reaction product accumulates on the objects (2) during the reaction to reduce the rate of the reaction.


Patent
Durham University | Date: 2017-04-05

A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.


Steed J.W.,Durham University
Trends in Pharmacological Sciences | Year: 2013

Pharmaceutical co-crystal formation represents a straightforward way to dramatically influence the solid-state properties of a drug substance, particularly its solubility and hence bioavailability. This short review summarises this highly topical field, covering why the topic is of interest in pharmaceutical formulation, the definitions and practical scope of co-crystals, co-crystal preparation and characterisation, and implications for regulatory control and intellectual property (IP) protection. Concepts are illustrated with highly selected examples of pharmaceutical co-crystal systems within the wider context of crystal engineering and research in molecular solids. © 2012 Elsevier Ltd.


Steed J.W.,Durham University
Chemical Society Reviews | Year: 2010

This tutorial review looks at the formation of low molecular weight gels from molecular principles using the well-explored supramolecular chemistry of ureas as an example. Synthesising lessons learned from classical urea inclusion chemistry, ureas in crystal engineering, ureas in self-assembly, urea functional groups in anion binding and sensing, and ureas as organocatalysts lead to the development and understanding of a new class of anion-tunable, urea-based soft materials. This review concludes with a look at emerging application areas for tunable gel-phase materials as controlled crystal growth media, both in templating metallic nanoparticles and in the growth and isolation of high quality crystals of molecular organic compounds, including polymorphic pharmaceuticals. © 2010 The Royal Society of Chemistry.


The concept of a molecular-based electronic technology has been evolving for over 50 years, and the development of molecular designs for such components over this period has drawn heavily on studies of intramolecular charge transfer in mixed-valence complexes and related systems. Recent advances in methods for the assembly and measurement of device characteristics of metal|molecule|metal junctions have brought the realisation of the considerable promise of the area within a tantalisingly close reach. This review presents a selective summary of the chemistry, spectroscopic properties and electronic structures of bimetallic complexes [{LxM}(μ-bridge){MLx}]n+ based primarily, but not exclusively, on the Ru(PP)Cp' and Mo(dppe)(η-C7H7) fragments and alkynyl based bridging ligands. The molecular design strategies that lead to a wide spectrum of electronic characteristics in these systems are described. Examples range from weakly coupled mixed-valance complexes through more strongly coupled systems in which the electronic states of the bridging ligand are intimately involved in electron transfer processes to complexes. An argument is made that the latter are better described in terms of redox non-innocent bridging ligands supported by metal-based donor substituents rather than strongly coupled mixed-valence complexes. The significance of these results on the further development of metal complexes for use as components within a hybrid molecular electronics technology are discussed. © 2012 Elsevier B.V.

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