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Wageningen, Netherlands

Li F.,Dreijenplein | Dea Wolf F.A.,Dreijenplein | Marcelis A.T.M.,Dreijenplein | Sudholter E.J.R.,Julianalaan | And 2 more authors.
Angewandte Chemie - International Edition | Year: 2010

Trigger the block: Stable biocompatible protein polymersomes can be generated by a triggered templated self-assembly route (see picture). Pluronic L121 vesicles (red core with blue corona) take up a biosynthetic triblock copolymer CSXSXC into their unilamellar shell. In response to changes in pH (trigger), the Sa block becomes hydrophobic and adapts to the template vesicle, thus directing the formation of protein polymersomes. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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