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Lübeck, Germany

Nitz C.V.,University of Lubeck | Schlichting S.,Dragerwerk AG and Co. KgaA | Pohlsen S.,Drager Medical GmbH | Hofmann U.G.,University of Lubeck | Hofmann U.G.,Albert Ludwigs University of Freiburg
Biomedizinische Technik | Year: 2012

Monitoring vital signs is one of the most crucial components of modern health care. This paper deals with the transmission of patient's vital signs to mobile devices using Web Services and their presentation on such devices. The architecture of the implementation with emulated data transmitted using Web Services is introduced as well as the generation of the Web Service communication interface. The gSOAP toolkit used for the communication interface is presented, as well as the integration of the generated files in the sourcecode. Finally, a presentation of the achieved visualization is given and concludes with a prospect. © 2012 by Walter de Gruyter Berlin Boston.

Grossherr M.,University of Lubeck | Hengstenberg A.,Dragerwerk AG and Co. KgaA | Papenberg H.,University of Lubeck | Dibbelt L.,University of Lubeck | And 4 more authors.
Clinica Chimica Acta | Year: 2011

Background: The lung protecting effect of propofol requires methods to measure the propofol concentration of the epithelial line fluid covering the alveolar surface.We hypothesized that (1) propofol can be determined in bronchoalveolar lavage (BAL) by reversed phase high performance liquid chromatography with fluorescence detection. (2) Positive end-expiratory pressure (PEEP) ventilation may have an effect on propofol concentration in BAL (cpB). Methods: 76 surgical patients were investigated after institutional review board approval. After criteria-based exclusion 45 samples were included. For group I (n=15) BAL was performed directly after induction, for group Z (n=15, PEEP=0cm H2O) and P (n=15, PEEP=10cm H2O) at the end of anaesthesia. BAL and plasma samples were analysed for propofol by reversed phase high performance liquid chromatography with fluorescence detection. Data from all groups were compared by non-parametric Mann-Whitney U-test. Results: Propofol can be detected in BAL. CpB varied between 23 and 167μglμ1 in all groups. Patients ventilated with PEEP (group P) showed significantly higher cpB (median 74.5μglμ1) compared to those immediately after induction of anaesthesia (median 42.0μglμ1) (group I), but not to those ventilated without PEEP in group Z (median 52.5μglμ1). Conclusion: Epithelial line fluid, sampled by BAL, can be used to determine cpB by reversed phase high performance liquid chromatography with fluorescence detection. Continuous propofol infusion and PEEP ventilation may have an effect on cpB. © 2010 Elsevier B.V.

Gorges M.,University of Utah | Kuck K.,Dragerwerk AG and Co. KgaA | Koch S.H.,University of Utah | Koch S.H.,University of Heidelberg | And 2 more authors.
Dimensions of Critical Care Nursing | Year: 2011

Although nurses perform the majority of the clinical tasks in an intensive care unit, current patient monitors were not designed to support a nurse's workflow. Nurses constantly triage patients, deciding which patient is currently in the most need of care. To make this decision, nurses must observe the patient's vital signs and therapeutic device information from multiple sources. To obtain this information, they often have to enter the patient's room. This study addresses 3 hypotheses. Information provided by far-view monitoring displays (1) reduces the amount of time to determine which patient needs care first, (2) increases the accuracy of assigning priority to the right patient, and (3) reduces nurses mental workload. We developed 2 far-view displays to be read from a distance of 3 to 5 m without entering the patient's room. Both display vital signs, trends, alarms, infusion pump status, and therapy support indicators. To evaluate the displays, nurses were asked to use the displays to decide which of 2 patients required their attention first. They made 60 decisions: 20 with each far-view display and 20 decisions with a standard patient monitor next to an infusion pump. Sixteen nurses (median age of 27.5 years with 2.75 years of experience) participated in the study. Using the 2 far-view displays, nurses more accurately and rapidly identified stable patients and syringe pumps that were nearly empty. Median decision times were 11.3 and 12.4 seconds for the 2 far-view displays and 17.2 seconds for the control display. The 2 far-view displays reduced median decision-making times by 4.8 to 5.9 seconds, increased accuracy in assignment of priority in 2 of 7 patient conditions, and reduced nurses' frustration with the triaging task. In aclinical setting, the proposed far-view display might reduce nurses' mental workload and thereby increase patient safety. Copyright © 2011 Lippincott Williams & Wilkins.

Baether W.,Dragerwerk AG and Co. KgaA | Zimmermann S.,Leibniz University of Hanover | Gunzer F.,German University in Cairo
Analyst | Year: 2012

Ion mobility spectrometry (IMS) is well known for its very high sensitivity, and thus IMS spectra are commonly used in the identification of trace gases. Extracting quantitative information from IMS spectra is, in contrast, difficult, especially regarding the reproducibility due to the nature of the processes involved in the measurement of the spectra. Here we present data extracted from signal decay curves obtained with a pulsed IMS, which can support the determination of substance concentrations in the lower ppb range with good stability. © 2012 The Royal Society of Chemistry.

Ibach B.,RWTH Aachen | Benzko J.,RWTH Aachen | Schlichting S.,Dragerwerk AG and Co. KgaA | Zimolong A.,Synagon GmbH | Radermacher K.,RWTH Aachen
Biomedizinische Technik | Year: 2012

With the increasing documentation requirements and communication capabilities of medical devices in the operating room, the integration and modular networking of these devices have become more and more important. Commercial integrated operating room systems are mainly proprietary developments using usually proprietary communication standards and interfaces, which reduce the possibility of integrating devices from different vendors. To overcome these limitations, there is a need for an open standardized architecture that is based on standard protocols and interfaces enabling the integration of devices from different vendors based on heterogeneous software and hardware components. Starting with an analysis of the requirements for device integration in the operating room and the techniques used for integrating devices in other industrial domains, a new concept for an integration architecture for the operating room based on the paradigm of a service-oriented architecture is developed. Standardized communication protocols and interface descriptions are used. As risk management is an important factor in the field of medical engineering, a risk analysis of the developed concept has been carried out and the first prototypes have been implemented. © 2012 by Walter de Gruyter.

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