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Yuksek S.K.,Ankara Childrens Hematology Oncology Training and Research Hospital | Aycan Z.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Oner O.,Ankara University
JCRPE Journal of Clinical Research in Pediatric Endocrinology | Year: 2016

Objective: To investigate the incidence of iodine deficiency (ID) and its effects on mental function in children referred to the Dr. Sami Ulus Maternity and Children’s Training and Research Hospital with a prospective diagnosis of attention deficit/hyperactivity disorder (ADHD). Methods: The study was conducted on 89 children referred in the period from September 2009 to June 2010 with a diagnosis of ADHD. A questionnaire was given to all parents. Conners’ rating scales were applied to the parents (CPRS) and teachers (CTRS), and revised Wechsler intelligence scale for children (WISC-R) to the children. Serum thyroid-stimulating hormone, free triiodothyronine and free thyroxine, thyroglobulin, anti-thyroid peroxidase, antithyroglobulin, and urinary iodine levels were measured in all children. Results: Median age was 9.41±1.95 years, and 83.1% of subjects were male. The mean urinary iodine level of the children was 92.56±22.25 µg/L. ID was detected in 71.9% of subjects and all were mild ID. There was no significant relationship between urinary iodine levels with WISC-R subtest scores and CPRS. However, a significant association was found between urinary iodine levels and hyperactivity section of CTRS (p<0.05). Likewise, a significant relationship was found between learning disorder/mental retardation diagnosis and freedom subtest of WISC-R (p<0.05). Conclusion: This study highlights the effects of ID on comprehension, perception, attention, and learning. However, the results need to be supported by new randomized controlled trials. © 2016, Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing.

Erdogan D.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital
Journal of the College of Physicians and Surgeons Pakistan | Year: 2013

Gastric perforation in neonates is an uncommon condition. A four-day-male neonate was referred with respiratory distress, abdominal distention, right scrotal swelling and extensive emphysema of the abdominal wall. Abdominal X-ray findings showed bilateral sub-diaphragmatic free air, right scrotal pneumatocele and subcutaneous emphysema of the abdominal wall. During the operation, pre-pyloric perforation was determined. Primary repair by single layer suture was performed and postoperative period was uneventful.

Ozalp E.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Aydin-Teke T.,Divisions of Infectious Diseases | Tanir G.,Divisions of Infectious Diseases | Ozkan M.,Divisions of Neurology | Bayhan G.I.,Divisions of Infectious Diseases
Turkish Journal of Pediatrics | Year: 2012

Rotavirus is a common cause of acute gastroenteritis in young children. Neurological complications including seizures are known to accompany rotavirus gastroenteritis. Acute flaccid paralysis (AFP) associated with rotavirus has not been reported previously except for one report. Herein, we describe a case of transient AFP and seizures associated with rotavirus gastroenteritis. We think that transient AFP can be seen during mild rotavirus gastroenteritis in children, but further studies may be necessary to understand the role of rotavirus as a cause of AFP in children.

Ozguner I.F.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Kizilgun M.,Ankara Childrens Hematology and Oncology Training and Research Hospital | Karaman A.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Cavusoglu Y.H.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | And 4 more authors.
European Journal of Pediatric Surgery | Year: 2014

Background/Purpose The aim of the study is to evaluate the diagnostic value of interleukin-6 (IL-6) level and neutrophil cluster of differentiation 64 (CD64) expression in diagnosis of acute appendicitis (AA). Methods A prospective controlled trail was performed. Children who were hospitalized with a diagnosis of right lower quadrant pain were our cohort. Serum samples for white blood cell, C-reactive protein (CRP), leukocyte CD64 expression, and IL-6 were obtained from the patients just after their admission. Operation was performed if appendicitis seemed probable, others were observed actively. Patients who had noncomplicated appendicitis were Group 1, patients who had complicated appendicitis were Group 2, and patients who had discharged after observation without operation with a diagnosis of nonspecific abdominal pain and had negative appendectomy without another surgical disease were Group 3. Results In this study, 49 patients were enrolled. CRP and CD64 levels were found higher in Group 2. IL-6 levels were found to be lower in Group 3 than Groups 1 and 2. Conclusions There was a difference between Group 2 and the other groups about CD64 levels. The CRP level and expression of leukocyte CD64 level did not effectively predict the diagnosis of noncomplicated appendicitis, but it predicted well the patients with complicated appendicitis. However, IL-6 levels are statistically significantly different between Group 3 and Groups 1 and 2. According to this result, IL-6 levels predicted well the patient with appendicitis. Applying additional diagnostic methods such as IL-6 levels seems to be helpful in reducing the numbers of false-positive diagnosis of AA. © 2014 Georg Thieme Verlag KG Stuttgart · New York.

Yilmaz G.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Caylan N.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Karacan C.D.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Bodur I.,Dr Sami Ulus Maternity And Childrens Training And Research Hospital | Gokcay G.,Istanbul University
Journal of Human Lactation | Year: 2014

Background: Cup feeding has been used as an alternative feeding method for preterm infants. Objective: The purpose of this study was to determine the effect of bottle and cup feeding on exclusive breastfeeding rates at hospital discharge and 3 and 6 months post-discharge in late preterm infants. Methods: Included in the study were preterm infants of 32 to 35 weeks' gestation fed only by intermittent gastric tube at the time of recruitment; 522 infants were randomly assigned to 2 groups: the cup-fed group (n = 254) and bottle-fed group (n = 268). Main outcomes were prevalence of exclusive breastfeeding at discharge and 3 and 6 months after discharge, and length of hospital stay. Results: Infants randomized to cup versus bottle feeding were more likely to be exclusively breastfed at discharge home (relative risk [RR], 1.58; 95% confidence interval [CI], 1.36-1.83), 3 months after discharge (RR, 1.64; 95% CI, 1.42-1.89), and 6 months after discharge (RR, 1.36; 95% CI, 1.14-1.63). There was no significant difference between groups for length of hospital stay. The mean hospital stay was 25.96 ± 2.20 days in the bottle-fed group and 25.68 ± 2.22 days in the cup-fed group. There was no significant difference between groups for time spent feeding, feeding problems, or weight gain in hospital. Conclusion: Cup feeding significantly increased the likelihood of late preterm infants being exclusively breastfed at discharge and 3 and 6 months after discharge, and cup feeding did not increase the length of hospital stay. Overall, we recommend cup feeding as a transitional method prior to breastfeeding for late preterm infants during hospitalization. © The Author(s) 2014.

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