Dr Rafiq Zakaria College For Women

Aurangābād, India

Dr Rafiq Zakaria College For Women

Aurangābād, India
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Bora R.O.,Post Graduate and Research Center | Dar B.,Post Graduate and Research Center | Dar B.,Indian Institute of Integrative Medicine | Pradhan V.,Dr Rafiq Zakaria College For Women | And 2 more authors.
Mini-Reviews in Medicinal Chemistry | Year: 2014

In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism. © 2014 Bentham Science Publishers.


Ali N.A.S.,Dr Rafiq Zakaria College For Women | Dar B.A.,Dr Rafiq Zakaria College For Women | Dar B.A.,Indian Institute of Integrative Medicine | Pradhan V.,Dr Rafiq Zakaria College For Women | Farooqui M.,Dr Rafiq Zakaria College For Women
Mini-Reviews in Medicinal Chemistry | Year: 2013

The present review article is related with the method of preparation, importance and medicinal application of indole and indazoles. The studies of heterocycles is an evergreen field in the branch of organic chemistry and always attract the attention of chemists working not only in the area of natural products but also in the synthetic chemistry. Moreover many useful drugs have emerged from the successful investigation carried out in this branch. The derivatives of indoles and indazoles exhibits antibacterial, anticancer, antionidants, anti-inflammatory, antidiabetic, antiviral, atniproliferative, antituberculosis, antispermetogenic activity, antipsychotic drugs etc. © 2013 Bentham Science Publishers.


Jadhav S.A.,Vivekanand Arts S D Commerce And Science College | Sarkate A.P.,Dr. Babasaheb Ambedkar Marathwada University | Farooqui M.,Dr Rafiq Zakaria College For Women | Shinde D.B.,Shivaji University
Synthetic Communications | Year: 2017

We have developed simple, greener, safer multicomponent synthesis series of 4-arylidene-2-phenyl-5(4H) oxazolones 4(a-r) catalyzed by Bronsted acid ionic liquid as triethylammonium hydrogen sulfate [Et3NH][HSO4] and catalytic amount of acetic anhydride and sodium acetate with excellent yields (90–99%). The protocol offers economical, environmentally benign, solvent-free conditions, and recycle–reuse of the catalyst and easily available starting as benzoyl chloride 1, amino acid 2 and a variety of aldehydes 3. The cyclization followed by condensation of benzoyl chloride, amino acid, and a variety of aldehydes catalyzed by ILs [Et3NH][HSO4] and catalytic amount of acetic anhydride and sodium acetate. The final products were confirmed by their characterization data such as FTIR, 1H-NMR, 13C-NMR, Mass, high-resolution mass spectra and were compared with its reported method. © 2017 Taylor & Francis


Tayade D.T.,Government Vidharbha Institute of Science and Humanities | Farooqui M.,Dr Rafiq Zakaria College For Women
Journal of Chemical and Pharmaceutical Research | Year: 2012

S-Triazine and thiocarbamide group containing drug create their own identity in the drug, pharmaceutical and medicinal sciences in last four decades.Hence, the viscometric measurements of recently synthesized drugs viz. 1- (4-hydroxy)-S-triazino-3-p-chlorophenylthiocarbamide(L 1),1-(4-hydroxy)-S-triazino-3-allylthiocarbamide(L 2) and 1-(4-hydroxy)-S-triazino-3-t-butylthiocarbamide(L 3), were carried out at various percentage compositions of solvent to investigate effect of structure, group on S-triazinothiocarbamides, The data and result obtained during this investigation gave detail information regarding drug absorption, transmission, activity and effect of these drugs. Taking all these things into consideration this research work was carried out.


Farooqui M.,Dr Rafiq Zakaria College For Women | Pardeshi R.,S R College Ghansawangi | Jadhav S.,Vivekanand College
Asian Journal of Pharmaceutical and Clinical Research | Year: 2016

Non-enzymatic vitamin C (ascorbic acid) plays an important role in the medicinal field and acts as antioxidants use in fruits and vegetable such as lemon, orange, grapes, carrots, tomatoes, grapefruit, beans, broccoli, and mangos. It helps to prevent and stop of various diseases such as lung cancer, asthma, and wheezing and finding an antibronchospastic effect. Other factors such as diet have also been implicated in the development of lung cancer. Despite the extensive research conducted in this area, the relationship between diet and lung cancer is still not clear. Diets high in fat and low in vegetables and fruits may increase the risk of lung cancer and other fact eating of tobacco and smoking of cigarette. Lung tissue damage due to high levels of free radicals in cigarette smoke causes direct (tissue oxidation) and indirect (release of oxidizing agents and enzymes). Vitamin C is necessary for phagocytosis. It plays a significant role in daily life, dietary system like eating food, vegetable and smoking of cigarette. It helps to prevent or stop the damage the lung tissue/or cause lung cancer. The present review studied that application of vitamin C act as antioxidant in lung cancer like diseases such as lung-cancer and role in lung function. © 2016, Innovare Academics Sciences Pvt. Ltd. All rights reserved.


Moghal M.M.,Maulana Azad National Institute of Technology | Ladniya V.,Maulana Azad National Institute of Technology | Pradhan V.,Dr Rafiq Zakaria College For Women
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2016

Gas Chromatography Mass Spectrometry (GC-MS) is unique method for the analysis and measuring quantity of organic volatile and semi-volatile compounds. Gas chromatography is applied to separates mixtures into individual components employing a temperature-controlled capillary column. Mass spectrometry is applied to recognize a variety of components from their mass spectra. In the present study volatile/semi-volatile compounds present in Oil extracted from Freshwater Edible Crab (Barytelphusa Cunicularis) are analyzed. Crab oil is extracted by Supercritical fluid extraction method and then analyzed by Gas Chromatography/Mass Spectrometry (GC/MS). A total of 60 volatile/semi-volatile compounds are found and quantified in this study.


Jirekar D.B.,Anandrao Dhonde Alias Babaji College | Pathan A.A.,Maulana Azad College Aurangabad | Farooqui M.,Maulana Azad College Aurangabad | Farooqui M.,Dr Rafiq Zakaria College For Women
Oriental Journal of Chemistry | Year: 2014

Experimental investigation was carried out by using commercially available husk of green gram (phaseolusaureus) seed to removal ofmethylene blue from aqueous medium. Husk of green gram seed was characterized by performing particle size distribution. The effect of contact time, effect of initial concentration of dye, effect of dosage, effect of salt, effect of pH, zero point pH and effect of temperature were studied in batch technique. Adsorption kinetic was verified by pseudo-first-order and pseudo-second-order models. The rate of adsorption of methylene bluefollowed by pseudo-second-order model for the dye concentration studied in the present case. Adsorption of methylene blue on green gram (phaseolusaureus) seed husk is also followed by Langmuir and Freundlich adsorption isotherm.


Rai M.,Dr Rafiq Zakaria College for Women | Kawde P.B.,R and D Glenmark pharmaceuticals
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2013

A simple, precise and rapid stability-indicating HPLC method was developed for the simultaneous quantitative determination of Olmesartan, Amlodipine and Hydrochlorothiazide from their innovative Pharmaceutical combination drug product, with the presence of degradation products. The separation was achieved on simple gradient method. The detector wavelength was 260 nm. The total runtime was 25 min. and RTof Hydrochlorothiazide, Amlodipine and Olmesartan are 4.2, 11.2 and 16.8 min.respectively. The described method was validated with respect to system suitability, specificity, linearity, precision and accuracy.


Al-Saeedi A.,Postgraduate and Research Center | Farooqui M.,Postgraduate and Research Center | Farooqui M.,Dr Rafiq Zakaria College for Women
Oriental Journal of Chemistry | Year: 2013

The (4+2) cycloaddition or the Dials-Alder reaction is one of the most important reactions in the field of organic synthesis. The Dials-Alder reaction well known to all chemists is 100 years old. The Diels-Alder reaction during that period it has been studied intensively, where there are more papers, many books and reviews in the Dials-Alder reactions making the complete study of these works impossible, therefore in this article we concentrate on the review and generalization of the Diels-Alder reaction of 9-substituted anthracene with a variety of dienophiles.


Durrani A.,Dr Rafiq Zakaria College For Women
Rasayan Journal of Chemistry | Year: 2011

pH-metry have been used most widely for the simultaneous equilibrium of transition metals with different amino acids like Histidine, Glutanic acid, Proline and L-aspartic acid using aqua-organic solvents. The ionic strength was maintained and complex formation was observed. © 2011 RASAYAN. All rights reserved.

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