Dr Behcet Uz Childrens Hospital

İzmir, Turkey

Dr Behcet Uz Childrens Hospital

İzmir, Turkey
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Songu M.,Dr Behcet Uz Childrens Hospital | Songu M.,Izmir Ataturk Research and Training Hospital | Adibelli H.,Dr Behcet Uz Childrens Hospital
International Journal of Pediatric Otorhinolaryngology | Year: 2010

Objective: The prominent ear is the most common congenital deformity of the auricle. It is often recommended that prominent ears be surgically repaired before children start school and most surgeons seem to perform the surgery after 5 years of age. The aim of our study is to summarize the rationale of performing otoplasty procedure in children under the age of 5, to discuss the advantages and disadvantages, and to review the patient (parent) satisfaction. Methods: A retrospective study was performed on 10 children under the age of 5 who underwent otoplasty procedure and was followed for over a year. Results: Ten patients (3 boys and 7 girls) between the ages of 48 months and 59 months, with a median age of 51.5 months were evaluated. Otoplasty was bilateral in 8 patients and unilateral in 2 patients. Global Aesthetic Improvement Scales of the patients were rated as "improved" or "better" at 52 weeks. The patient (parent) satisfaction was measured by a telephone survey. Parents revealed that 9 out of 10 were "very" or "completely" satisfied with the appearance and symmetry of their children's ears. We did not observe any visible disturbance or growth restriction in our patients, even in the unilateral operated group. Conclusion: Timing of surgery is an issue of concern with regard to otoplasty in children. There may be significant psychosocial benefit to early intervention, particularly in light of changing norms for interaction with peers at ages considerably earlier than what had previously been thought of as the "school age." Our preference is to plan the otoplasty as young as four years of age, after the child has expressed some concern about the deformity. © 2009 Elsevier Ireland Ltd.

Afsar F.S.,Dr Behcet Uz Childrens Hospital | Afsar F.S.,Ataturk Research and Training Hospital
Cutaneous and Ocular Toxicology | Year: 2011

Purpose: The aim of this study was to determine the real spectrum of skin diseases in Turkish children and how they were managed. Methods: Data on a total of 6000 consecutive patients aged 0-18 years attending the pediatric dermatology clinic were analyzed for diagnosis, disease group, diagnostic pattern, treatment modality, and referral and hospitalization frequency. Results: Allergic skin diseases (49.9%) were the leading group of dermatoses, which were followed by infectious diseases (20.5%), and disorders of skin appendages (10.2%). Atopic dermatitis was the most common dermatose, which was followed by papular urticaria and unclassified eczema. Most of the patients (92.0%) had diagnosis on clinical basis, whereas skin biopsy was performed in 3.7% and laboratory investigation in 4.4% of the patients. The hospitalization rate was 0.3%, and Henoch-Schönlein purpura was the most frequent dermatose for which hospitalization was required. Local treatment was prescribed in 56.0% of the patients, local treatment and systemic treatment together in 26.4%, and systemic treatment in 6.2%. Viral warts followed by viral exanthems caused by enteroviruses and acquired melanocytic nevi were the most frequently referred skin problems. Further investigation and treatment for systemic or related diseases was the most common reason for referrals (2.1%), and pediatrics was the department to which most of the referrals were made (1.8%). Conclusion: This study provided important data on the spectrum of skin diseases encountered in the pediatric age groups and general approach to patients in a pediatric dermatology clinic in Turkey. © 2011 Informa Healthcare USA, Inc.

OBJECTIVE: To study the factors affecting a neurodevelopmental status of children with congenital hypothyroidism, diagnosed on national screening program.METHODS: The study was performed in the Pediatric Endocrinology Department of Dr. Behcet Uz Children's Hospital between May 2012 and May 2013. Children with congenital hypothyroidism, aged between 24 and 36 months, diagnosed by national screening program were included in the study group. Healthy subjects at the same age group consisted of the control group. For the neurodevelopmental evaluation, Bayley Scale of Infant Development- II (BSID-II) was used. Factors possibly effective on neurodevelopment were evaluated.RESULTS: 42 patients and 40 healthy children (mean (SD) age, 29.4 (3.7) and 29.2 (3.5), respectively were included in the study. The mean MDI score [92.6 (7.07) vs 97.1 (9.69), P=0.14)] and the mean PDI score [97.8 (15.68) vs 99.1 (10.57), P=0.66)] in the study group and control group were not significantly different. Among the patient, 4.6% and 4.7% children were moderately retarded as per the MDI scores and PPI scores, respectively. The sex, socioeconomic status, birth weight, screening levels of TSH, severity of the congenital hypothyroidism, initiation time and the dosage of thyroid hormone replacement, length of the normalization period of TSH, and adherence to treatment were not found to affect the MDI and PDI scores of the patients.CONCLUSION: Some children with congenital hypothyrodism may have mild to moderate neurodevelopmental retardation, despite the early diagnosis and treatment, and thus need to be under regular follow-up for neurodevelopmental status.

Kamer E.,1834 sok. No 9 4 | Unalp H.R.,Ankent Bl. No 7 | Diniz G.,Dr Behcet Uz Childrens Hospital | Bozdag A.D.,Mithatpasa Cad. No 387 7 | Ortac R.,Dr Behcet Uz Childrens Hospital
Langenbeck's Archives of Surgery | Year: 2010

Purpose We aimed to investigate the effect of sildenafil on the healing process of abdominal wall wound in rats. Materials and methods The study was performed with adult female Wistar-Albino rats. Control group (n=50) were fed on standard laboratory diet until 12 h before surgery. Study group (n=50) were applied orally with orogastric tube 10 mg/kg once a day for 10 days of sildenafil therapy. Each rat was anesthetized, and a 4-cmlong midline laparotomy was performed. Ten animals from each group were killed at postoperative days (PODs) 4, 7, 14, 21, and 35. Breaking strength analysis was measured, and the abdominal incision wounds were examined histologically. Results Breaking strength for the midline incision, acute inflammation score on POD 14, and neovascularization on PODs 7, 14, 21, and 35 were significantly higher in the study group. Conclusions Sildenafil can be used as a supporting factor in wound healing. © Springer-Verlag 2009.

Songu M.,Dr Behcet Uz Childrens Hospital | Adibelli H.,Dr Behcet Uz Childrens Hospital | Diniz G.,Izmir Dr Behcet Uz Childrens Hospital
Pediatric Dermatology | Year: 2012

White sponge nevus is a rare, autosomal-dominant disorder that affects the noncornified stratified squamous epithelia. Clinically, the presence of white, spongy plaques mostly in the buccal, labial, and gingival mucosa and the floor of the mouth characterize the lesions. The differential diagnosis of the lesion may be difficult and it is best diagnosed by biopsy. We report a case of white sponge nevus in the oral cavity of a 16-year-old boy and review of the literature. © 2012 Wiley Periodicals, Inc.

Songu M.,Dr Behcet Uz Childrens Hospital | Songu M.,Izmir Kâtip Celebi University | Kutlu A.,Dr Behcet Uz Childrens Hospital
European Archives of Oto-Rhino-Laryngology | Year: 2014

To investigate health-related quality of life changes that occurred in children with prominent ears applied pre- and postoperatively. A prospective study was performed in 67 consecutive children who underwent otoplasty procedures between April 2008 and July 2010 and followed up for more than 2 years. Evaluations and interviews performed in the pre-and postoperative periods included the patients' history, clinical and routine laboratory examinations. Glasgow children's benefit inventory was the basis of the used inquiry for detecting the changes in health-related quality of life after otoplasty. For the children's cohort, the mean total Glasgow children's benefit inventory score was 23.9 (p < 0.001), indicating a benefit from the operation. All Glasgow children's benefit inventory subscores (emotion, physical health, learning, and vitality) were raised (mean 30.84, 14.98, 18.89, and 23.96, respectively). The health-related quality of life was raised in 63 of 67 children (94.03 %). Negative Glasgow children's benefit inventory scores or subscores were not found in a single case. Otoplasty can significantly increase patients' health-related quality of life and leads to a high rate of patient satisfaction in children with prominent ears. © 2014 Springer-Verlag.

Erikci V.,Dr Behcet Uz Childrens Hospital | Hosgor M.,Dr Behcet Uz Childrens Hospital
Journal of Plastic, Reconstructive and Aesthetic Surgery | Year: 2014

Introduction A retrospective clinical trial was conducted to evaluate the clinical features and treatment outcomes and to determine the incidence of complications in children with congenital neck lesions (CNLs) treated at our institution with a special emphasis on thyroglossal duct remnant (TGDR), branchial cleft anomaly (BCA), and dermoid cyst (DC). Materials and methods This series had 72 patients with CNL. The diagnosis of CNL was made by physical examination, ultrasound (US) in most, and for a potential extension of the mass computed tomography (CT) or magnetic resonance imaging (MRI) in a few patients and confirmed by histopathological examination in all of the children. Results Of the patients in this series, 39 (54.2%) children had thyroglossal duct remnant (TGDR). The most common surgical procedure (n = 36) in these children was Sistrunk's procedure. Four children (10.3%) with TGDR had associated anomalies including Turner syndrome and Morgagni hernia. During the study period, 25 (34.7%) children with branchial cleft anomaly (BCA) were treated and most of these were second branchial anomalies. There were eight children (11.1%) with dermoid cyst (DC). Conclusion TGDR is the most common CNL and is presented clinically rather late with regard to BCA and DC in this series. Surgical resection is optimal choice of therapy in CNLs not only for aesthetic reasons but also for the recurrent infections and the potential danger of malignancy. Definitive surgery may be associated with high morbidity, especially recurrence. Associated anomalies may be observed, especially in children with TGDR. Although the Sistrunk's procedure is a safe and successful technique, life-threatening complications should also be kept in mind during the management of these lesions and early and adequate surgical treatment is suggested. © 2014 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Genel F.,Dr Behcet Uz Childrens Hospital | Atlihan F.,Dr Behcet Uz Childrens Hospital | Ozsu E.,Dr Behcet Uz Childrens Hospital | Ozbek E.,Dr Behcet Uz Childrens Hospital
Journal of Infection | Year: 2010

Objectives: Down regulation of HLA-DR expression on monocytes has been reported in adult sepsis. The aims of this study were, first to evaluate monocyte HLA-DR expression in late onset neonatal infection and second to investigate the prognostic value of monocyte HLA-DR expression at onset of symptoms for the final outcome. Methods: Peripheral blood samples were taken from neonates, who were classified into three groups: late onset neonatal sepsis group (n= 40); non-infective disorders group (n= 24) and the control group (n= 25). Monocyte expression of HLA-DR was determined by flow cytometry. Results: The percentage of monocytes expressing HLA-DR was lower in neonates with late onset sepsis (p< 0.05). Of the 40 septic patients enrolled in the study, 32 survived, while 8 died. The percentage of HLA-DR expressing monocytes was significantly lower in the non-survivor sepsis group (16.6%) compared with that in the survivor sepsis group (45.2%). The optimal cutoff value of HLA-DR for predicting mortality was 30% with 87% sensitivity and 81% specificity. Patients with monocyte HLA-DR expression ≤30% had lower survival rate with a 30-fold higher risk of mortality (Odds ratio 30; 95% CI 3-295). Conclusion: According to our findings, monocyte HLA-DR expression seems to be an early predictive marker for the prognosis in late onset neonatal sepsis. © 2009 The British Infection Society.

Afsar F.S.,Dr Behcet Uz Childrens Hospital
Current Opinion in Pediatrics | Year: 2010

Purpose of review: In developing countries, where the majority of people have a low income and live in resource-poor settings, skin infections are prevalent. Data from recent studies provide insight into the most common skin infections and their management. Recent findings: Several studies confirm that skin infections account for the majority of pediatric mortality and morbidity in developing countries. They are prevalent in resource-poor settings and rural areas in certain parts of the world. Also, hot, humid climates and overcrowding predispose to skin infections. Most of the skin infections are curable with effective medication. Summary: Skin infections are of particular importance in developing countries. This review focuses on the most common skin infections and summarizes the most recent knowledge on the epidemiology, morbidity, and treatment in resource-poor settings. © 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.

Afsar F.S.,Dr Behcet Uz Childrens Hospital
Clinical and Experimental Dermatology | Year: 2010

Skin problems in children during the first few weeks of life can raise concern, even for experienced neonatologists and paediatric dermatologists. The skin of preterm and term newborn babies has distinct differences from juvenile and adult skin. An understanding of the nature of neonatal skin, the physiological and nonphysiological skin conditions of preterm and term neonates, and skin care are essential in paediatric practice. This article discusses the nature of the neonatal skin and its physiological phenomena. © 2009 British Association of Dermatologists.

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