Dr. Babasaheb Ambedkar Marathwada University

www.bamu.ac.in
Aurangabad, India

Dr. Babasaheb Ambedkar Marathwada University , formerly Marathwada University, is located in Aurangabad, Maharashtra, Republic of India. It is named after Bharat Ratna "Babasaheb" Ambedkar, an Indian jurist, political leader, academic and the chief architect of the Indian Constitution. This university was established primarily on the initiative of Babasaheb Ambedkar so as to fill the huge lacuna of higher education facilities in western Vidarbh, Marathwada and North maharashtra region.The university was established on August 23, 1958.It is one of the oldest premier university established by Maharashtra state government after Mumbai and Pune Universities.This university has contributed to the progress of adjoining regions and people in innumerable ways.Since its inception, the university has around 400 colleges affiliated to it, which come under four districts of Maharashtra State. The student population exceeds 100,000. Wikipedia.


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Sathe B.R.,Dr. Babasaheb Ambedkar Marathwada University
RSC Advances | Year: 2012

A simple and versatile route based on a galvanic displacement approach for the shape-selective evolution of Rh nanostructures followed by their in situ integration assembly on a large scale has been designed and successfully developed by using polyvinylpyrrolidone (PVP) as a shape inducing agent. Comparative studies on the electrocatalytic activity of these morphologies were conducted towards many fuel cell reactions as demonstrated by HCHO oxidation. © 2012 The Royal Society of Chemistry.


Shingate B.B.,Dr. Babasaheb Ambedkar Marathwada University | Shingate B.B.,CSIR - National Chemical Laboratory | Hazra B.G.,CSIR - National Chemical Laboratory
Chemical Reviews | Year: 2014

Sterols are compounds containing a perhydro-1,2-cyclopentenophenanthrene ring system and are found in a variety of different marine, terrestrial, and synthetic sources. During the early and middle years of sterol and related terpenoid chemistry, synthetic efforts were focused primarily on the ring system and some of the more simple functional side chains. Comparatively, little attention was paid to the side chain except for two carbon units present in corticosteroids and other pregnane derivatives and interconversions between the side chains of cholesterol, plant sterols, and bile acids. Information on the spectral properties of steroidal C-20 epimers is now available and permits us to make some generalizations. The spectra are influenced by several factors; therefore the generalizations may not be always directly applicable to new compounds.


Lomate P.R.,Dr. Babasaheb Ambedkar Marathwada University | Hivrale V.K.,Dr. Babasaheb Ambedkar Marathwada University
Plant Physiology and Biochemistry | Year: 2012

Wounding of plants by chewing insects or other damage induces the synthesis of defensive proteinase inhibitors (PI) in both wounded and distal unwounded leaves. In the present paper we report the characterization of inducible defensive PI from pigeon pea (Cajanus cajan) and its in vitro interaction with Helicoverpa armigera gut proteinases (HGP). We found that PI activity was induced in local as well as systemic leaves of pigeon pea by the wounding and methyl jasmonate (MeJA) application. Consistent induction of PI was observed in two wild cultivars of pigeon pea at various growth stages. The estimated molecular weight of inducible PI was ∼16.5 kDa. Electrophoretic analysis and enzyme assays revealed that the induced PI significantly inhibited total gut proteinase as well as trypsin-like activity from the midgut of H. armigera. The induced PI was found to be inhibitor of trypsin as well as chymotrypsin. Study could be important to know the further roles of defensive PIs. © 2012 Elsevier Masson SAS.


Sangshetti J.N.,Dr. Babasaheb Ambedkar Marathwada University | Shinde D.B.,Dr. Babasaheb Ambedkar Marathwada University
Bioorganic and Medicinal Chemistry Letters | Year: 2010

An improved protocol for the synthesis of a novel series of 1,2,4-triazines possessing 1,2,3-triazole and piperidine ring using 1-(1-substituted piperidin-4-yl)-1H-1,2,3-triazole-4-carbohydrazide, benzil, ammonium acetate and ZrOCl2·8H2O as a catalyst in ethanol-water has been presented. The yields obtained are in the range of 87-94%. All the synthesized compounds (4a-4l) are novel and were evaluated for their in vitro antifungal activity. SAR for the series has been developed by comparing their MIC values with miconazole and fluconazole. Based on activity data SAR for the series has been developed. Compound 4c from the series was equipotent to miconazole against Candida albicans (MIC-25), Aspergillus niger (MIC-12.5) and Cryptococcus neoformans (MIC-25). Compound 4d was equipotent with miconazole against all tested organisms except Cryptococcus neoformans. Also compound 4i was equipotent with miconazole against C. albicans, A. niger and Fusarium oxysporum. © 2009 Elsevier Ltd. All rights reserved.


Sangshetti J.N.,Dr. Babasaheb Ambedkar Marathwada University | Shinde D.B.,Dr. Babasaheb Ambedkar Marathwada University
European Journal of Medicinal Chemistry | Year: 2011

A novel series of 3-(1-(1-substituted piperidin-4-yl)-1H-1,2,3-triazol-4- yl)-5-substituted phenyl-1,2,4-oxadiazoles bearing 1,2,3-triazole and piperidine ring has been synthesized in one step from amidoxime using Carbonyl diimidazole (CDI) and K2CO3. All the synthesized compounds (4a-4r) are novel and evaluated for their in vitro antifungal activities. SAR for the series has been developed by comparing their MIC values with miconazole and fluconazole. Some of the compounds from the series like 4j was equipotent with miconazole against Cryptococcus neoformans whereas activities of compound 4m against Aspergillus niger and Aspergillus flavus were comparable to miconazole. Also compound 4r shows activity comparable to miconazole against Candida albicans, A. niger and A. flavus. © 2011 Elsevier Masson SAS. All rights reserved.


Sathe B.R.,Dr. Babasaheb Ambedkar Marathwada University
Physical Chemistry Chemical Physics | Year: 2013

Rh nanoneedles and nanorods have been generated with the help of functional molecules like hexamethylene tetraamine and tridecylamine (1:2 in mM scale) as effective capping agents for electrocatalytic studies. A noteworthy negative shift of the onset potential towards the electrooxidation of formic acid compared to that of bulk Rh from cyclic voltammetry along with current densities from current-time transient suggests their potential application as an efficient electrocatalyst for fuel cell. © the Owner Societies 2013.


Sathe B.R.,Dr. Babasaheb Ambedkar Marathwada University
AIP Advances | Year: 2012

Shape selective synthesis of Rh nanostructures has been demonstrated with the help of a single step chemical vapor deposition, where different shapes like cubes at 500 °C, pyramids and hexagons at 500 °C, 700 °C and 900 °C respectively have been obtained as a function of temperature. Scanning electron microscopy (SEM), X-ray diffraction (XRD), thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS) and four probe conductivity measurements were used to study the morphology, crystallinity and phase purity of the structures. The conductivity values for as synthesised nanostructures have been obtained in the range of 2-7 kS/cm2. On the basis of the experimental results, from TGA and XPS studies possible mechanistic pathway for the evolution of Rh nanostructures was discussed. © 2012 Copyright 2012 Author(s). This article is distributed under a Creative Commons Attribution 3.0 Unported License.


Kore P.S.,Dr. Babasaheb Ambedkar Marathwada University | Pawar P.P.,Dr. Babasaheb Ambedkar Marathwada University
Radiation Physics and Chemistry | Year: 2014

The mass attenuation coefficients of some amino acids, such as dl-aspartic acid-LR(C4H7NO4), l-glutamine (C4H10N2O3), creatine monohydrate LR(C4H9N3O2H2O), creatinine hydrochloride (C4H7N3O·HCl) l-asparagine monohydrate(C4H9N3O2H2O), l-methionine LR(C5H11NO2S), were measured at 122, 356, 511, 662, 1170, 1275 and 1330keV photon energies using a well-collimated narrow beam good geometry set-up. The gamma-rays were detected using NaI (Tl) scintillation detection system with a resolution of 0.101785 at 662keV. The attenuation coefficient data were then used to obtain the effective atomic numbers (Zeff), and effective electron densities (Neff) of amino acids. It was observed that the effective atomic number (Zeff) and effective electron densities (Neff) initially decrease and tend to be almost constant as a function of gamma-ray energy. Zeff and Neff experimental values showed good agreement with the theoretical values with less than 1% error for amino acids. © 2014.


Gacche R.N.,Dr. Babasaheb Ambedkar Marathwada University | Jadhav S.G.,Dr. Babasaheb Ambedkar Marathwada University
Journal of Experimental and Clinical Medicine | Year: 2012

Purpose: In the present investigation a series of coumarin derivatives (CDs) were evaluated for their in vitro antioxidant and anticancer activities. This study was to assess the suitability of a series of structurally different CDs as possible antioxidant and anticancer agents. Methods: The antioxidant studies were carried out using a 2,2,-diphenyl-1-picrylhydrazine (DPPH) radical scavenging assay, while the anticancer activity was assessed by performing the (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliuum bromide-based (MTT-based) cytotoxicity assay using different cancer cell lines. The physico-chemical properties of the test CDs related to free radical scavenging reactions and other biological properties were also calculated using BioMed Cache 6.1.10. Result: Selected CDs showed significant cytotoxicity against different cancer cell lines in an IC 50 range of 7.51-17.48 μM. All the selected CDs were demonstrated to have considerable concentration-dependent DPPH radical scavenging activity. Conclusion: These results may signify the importance of selected CDs as antioxidant and anticancer agents. © 2012.


Sathe B.R.,Dr. Babasaheb Ambedkar Marathwada University
RSC Advances | Year: 2013

The highly monodispersed decoration of Rh nanoparticles (∼2.5 nm) on acid-functionalized carbon nanospheres (CNSs) has been demonstrated using a facile wet-chemical method. The electrochemical studies of the resulting Rh-CNS hybrid material displayed excellent H2 sensing properties. © 2013 The Royal Society of Chemistry.

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