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Chu X.C.,Dongying Municipal Peoples Hospital | Cheng S.,Dongying Municipal Peoples Hospital | Yan S.Y.,Dongying Municipal Peoples Hospital
Chinese Journal of Tissue Engineering Research | Year: 2015

BACKGROUND: Stem cell transplantation has been shown to have many advantages in treatment of diseases. Its application can treat various diseases in many systems such as nervous system, immune system and endocrine system. Its advantage is incomparable. These are all credit to the special abilities, including easy sample collection, strong self proliferative ability, wide differentiation range, repair of injured tissue and immunoloregulation. OBJECTIVE: To explore the clinical effects of stem cell transplantation in treatment of nonunion. METHODS: A computer search was performed in CNKI database for articles concerning stem cell transplantation for nonunion published from 2005 to 2014. The key words were “stem cells, nonunion” in Chinese. 244 articles were analyzed, and typical literatures were further compared. RESULTS AND CONCLUSION: Stem cells have the abilities of self-renewal and differentiation. Their source is not limited, and the sample collection is convenient. Stem cells have small injury to the donor, do not have immunogenicity, and have fewer complications. The cost is low. Stem cells are easily isolated and cultured, can proliferate infinitely, and provide a pathway for severe bone injury such as nonunion, bone defects and comminuted fracture. The deep study of stem cells creates a new direction for nonunion treatment, and has achieved certain results in clinical trials.

Ren C.-W.,Dongying Municipal Peoples Hospital | Sun P.,Dongying Municipal Peoples Hospital | Han M.,Dongying Municipal Peoples Hospital | Jia Z.-Q.,Dongying Municipal Peoples Hospital | And 2 more authors.
Journal of Interventional Radiology (China) | Year: 2016

Objective To compare the occurrence rate of carotid sinus syndrome (CSS) during the performance of balloon-dilated carotid artery stenting ( CAS) between the left and right internal carotid arteries. Methods The clinical data of 64 patients with carotid artery stenosis, who had received CAS, were retrospective analyzed. The patients included 36 males and 28 females, with a mean age of 62.7 year old (49- 75 years). A total of 36 stenotic sites of the right carotid arteries and 30 stenotic sites of the left carotid arteries were detected; in two patients the carotid artery stenosis was bilateral. Severe stenosis (>70%) was seen in 37 lesions, and stenosis with ulcer plaque (30%-70%) was observed in 29 lesions. A total of 66 stents were implanted. Wallstent self-expanding stent was adopted in all patients. Results During the performance of CAS for 36 right carotid stenotic sites, the severe, moderate and mild CSS occurred in 5 (13.89%), 19 (52.78%) and 12 ( 33.33%) cases respectively, while for 30 left carotid stenotic sites the severe, moderate and mild CSS occurred in 3 (10.00%), 10 (33.33%) and 17 ( 56.67%) cases respectively. Hie differences in the occurrence rate of CSS between the right group and the left group were statistically significant (P<0.05). Conclusion CSS is a common complication in performing CAS. The occurrence of CSS of the right carotid CAS is higher than that of the left carotid CAS (J Intervent Radiol, 2016, 25: 568-570).

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