Song K.S.,Keimyung University |
Song K.S.,Dongsan Medical Center |
Lee S.W.,Keimyung University |
Bae K.C.,Keimyung University |
And 2 more authors.
Journal of Pediatric Orthopaedics Part B | Year: 2016
There are no published case series of nonunion of distal radius fractures in healthy children because of the rarity of its occurrence. We searched for all reported cases of this condition in Pubmed, Google scholar, and SCOPUS. We found three series, which included one previously reported by our group. The aim of the present study was to define the predisposing factors leading to nonunion after treatment of distal radius fractures in healthy children. We also aimed to emphasize that nonunion should be included in the list of complications of distal radius fractures in children and be mentioned in the textbook of pediatric trauma. © 2016 Wolters Kluwer Health, Inc.
Kim E.,Dongsan Medical Center
Journal of Neurological Surgery, Part A: Central European Neurosurgery | Year: 2015
Background The benefits of decompressive craniectomy (DC) may be adversely affected by postoperative complications. This article presents the technique of ultrasonography (US) guidance to treat epidural hematoma (EDH) following DC for ischemic stroke. Methods Four patients developed postoperative EDHs requiring dual-trajectory approaches for reexploration and evacuation. Clearance and reaccumulation of the EDH was assessed by US images at the bedside. Results Real-time US showed hematoma shrinkage and brain decompression during the suction-assisted evacuation. Aspiration resulted in an immediate average reduction in hematoma size from 106 mL to 30 mL. No ensuing infection and rehemorrhage occurred related to the bedside procedure. Conclusions US-guided clot evacuation is an effective minimal access surgery for patients with post-craniectomy EDHs and worsening neurologic status. Copyright © 2015, Georg Thieme Verlag KG. All rights reserved.
Efficacy and safety of deferasirox estimated by serum ferritin and labile plasma iron levels in patients with aplastic anemia, myelodysplastic syndrome, or acute myeloid leukemia with transfusional iron overload
Kim I.-H.,Inje University |
Moon J.-H.,Kyungpook National University |
Lim S.-N.,Inje University |
Sohn S.-K.,Kyungpook National University |
And 15 more authors.
Transfusion | Year: 2015
BACKGROUND Patients receiving red blood cell (RBC) transfusions are at risk of iron overload, which can cause significant organ damage and is an important cause of morbidity and mortality. STUDY DESIGN AND METHODS This study was an open-label, single-arm, prospective clinical study to evaluate the efficacy and safety of deferasirox (DFX) in patients with aplastic anemia (AA), myelodysplastic syndrome (MDS), or acute myeloid leukemia (AML). Patients with serum ferritin levels of at least 1000 ng/mL and ongoing transfusion requirements were enrolled. DFX was administered for up to 1 year. A total of 100 patients were enrolled. RESULTS Serum ferritin levels decreased significantly following treatment (from 2000 to 1650 ng/mL, p=0.004). The median absolute reduction in serum ferritin levels was -65 ng/mL in AA (p=0.037), -647 ng/mL in lower-risk MDS (MDS-LR; p=0.007), and -552 ng/mL in higher-risk MDS (MDS-HR)/AML (p=0.482). Mean labile plasma iron (LPI) levels decreased from 0.24 μmol/L at baseline to 0.03 μmol/L at 1 year in all patients (p=0.036). The mean LPI reduction in each group was -0.17 μmol/L in AA, -0.21 μmol/L in MDS-LR, and -0.30 μmol/L in MDS-HR/AML. Gastrointestinal disorders were commonly observed among groups (16.0%). DFX was temporarily skipped for adverse events in seven patients (7.0%) and was permanently discontinued in 11 patients (11.0%). CONCLUSION DFX reduced serum ferritin and LPI levels in patients with transfusional iron overload. Despite the relatively high percentage of gastrointestinal side effects, DFX was tolerable in all subgroups. © 2015 AABB.
Song K.S.,Dongsan Medical Center |
Lee S.W.,Dongsan Medical Center |
Bae K.C.,Dongsan Medical Center |
Sohn E.S.,Dongsan Medical Center
American journal of orthopedics (Belle Mead, N.J.) | Year: 2015
Aneurysmal bone cysts associated with tubular bones of the hand occur rarely and require particular diagnostic and therapeutic management techniques. While optimal treatment has not been established, accepted treatments range from aggressive radical treatment, including en bloc resection and excision diaphysectomy with strut bone grafting, to relatively simple techniques, such as thorough curettage followed by bone graft. Aggressive treatment approaches may be optimal for the cases with articular surface involvement, full-bone invasion of the phalanx or metacarpal, or more than 1 recurrence. We report a monocentric case of aneurysmal bone cysts involving metacarpal bone in a child who achieved favorable outcome with curettage and morselized cancellous bone grafts.
Usefulness of intravascular ultrasound guidance in percutaneous coronary intervention with second-generation drug-eluting stents for chronic total occlusions (from the multicenter Korean-chronic total occlusion registry)
Hong S.-J.,Yonsei University |
Kim B.-K.,Yonsei University |
Shin D.-H.,Yonsei University |
Kim J.-S.,Yonsei University |
And 11 more authors.
American Journal of Cardiology | Year: 2014
Despite the usefulness of intravascular ultrasound (IVUS) in percutaneous coronary intervention (PCI), the impact of IVUS guidance on clinical outcomes, particularly for chronic total occlusion (CTO) intervention, has rarely been studied. We sought to investigate the clinical usefulness of IVUS-guided CTO intervention with second-generation drug-eluting stent implantation. From 2007 to 2009, a total of 2,568 patients were enrolled in the Korean-CTO registry and 534 patients with successful implantation of second-generation drug-eluting stents were analyzed. IVUS-guided PCI was performed on 206 patients (39%). Clinical outcomes at 2 years were compared between the IVUS-guidance group and the angiography-guidance group in 201 propensity score-matched pairs. The primary end point was the occurrence of definite or probable stent thrombosis. Clinical characteristics were similar between both groups after matching. At 2 years, the IVUS-guidance group showed significantly less stent thrombosis than the angiography-guidance group (0% vs 3.0%, p = 0.014) and a lesser trend toward myocardial infarction (1.0% vs 4.0%, p = 0.058). Target lesion revascularization (TLR) and major adverse cardiovascular event rates were similar. However, a significant interaction was observed between the use of IVUS and lesion length for predicting the TLR (p = 0.037), suggesting usefulness of IVUS in long-lesion (≥3 cm) relative to short-lesion CTO. In conclusion, although IVUS-guided CTO PCI was not associated with a reduction in overall major adverse cardiovascular events, IVUS guidance appears to be associated with a reduction of stent thrombosis and myocardial infarction compared with angiography-guided CTO PCI. Additionally, TLR occurred less frequently in the IVUS-guidance group, especially for long lesions. © 2014 Elsevier Inc. All rights reserved.