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Suigen, South Korea

Shin G.-S.,Korean University of Science and Technology | Lee B.-R.,Korean University of Science and Technology | Chang K.-H.,Korean University of Science and Technology | Lee I.-J.,Dongnam Health College | And 2 more authors.
Radiation Protection Dosimetry | Year: 2010

This study examined the characteristics of the dental X-ray fluoroscopic equipment, 'DreamRay 60F', which was recently developed in Korea. The output linearity, output reproducibility, half-value layer (HVL), leakage radiation and scattered radiation were measured using an ionisation chamber. The surface dose equivalent rate and estimated dose equivalent of the operator were also calculated. The output linearity was 0.0015-0.0175 and the coefficient of variation for the output reproducibility was 0.0013-0.0074. The experimental HVL was 2.1 mm Al, and the leakage dose rate at 100 cm from the X-ray focus ranged from 2.70 to 19.66 μGy h -1 depending on the direction. The scattered radiation doses differed significantly (1.7-16.8 times) depending on the distance and direction. If an operator is exposed for 10 min per procedure, 5 procedures a day at 5 days a week, he/she sitting at a 90° direction will receive an annual dose equivalent of 13.0 mSv (at 30 cm) and 63.7 mSv (at 50 cm) in the trunk and face surface, respectively. © The Author 2010. Published by Oxford University Press.

Suh S.-J.,Sungkyunkwan University | Kim C.-H.,Sungkyunkwan University | Lee K.-H.,Dongnam Health College | Shin D.-B.,Jeju National University | Park S.-S.,Jeju National University
Journal of the Korean Society of Food Science and Nutrition | Year: 2015

To investigate the anti-cancer effect of shiitake mushrooms (Lentinus edodes) cultured in aloe-supplement, we treated extract of shiitake mushroom cultured in aloe-supplement (ESA) to MDA-MB-231 human breast cancer cells. ESA-treated MDA-MB-231 cells showed decreased growth rate in XTT assay. In addition migration/invasion was noticeably inhibited by ESA in TNF-α-treated MDA-MB-231 cells. Western blot analysis showed that the molecular mechanism of cell migration/invasion was mediated by reduced intercellular adhesion molecule-1 expression via p-ERK signal transduction pathways. We found ESA had inhibition activity against cellular growth and migration/invasion. Taken together, ESA has putative anti-cancer activity against human breast cancer. © 2015 Korean Society of Food Science and Nutrition. All Rights Reserved.

Lee Y.-I.,Dongnam Health College | Eom J.-H.,University of Seoul | Kim Y.-W.,University of Seoul | Song I.-H.,Korea Institute of Materials Science
Journal of the Korean Ceramic Society | Year: 2013

Cullet-loess tile bodies are successfully fabricated using cullet, loess, hollow microspheres, and sintering additives (borosilicate glass frit, boric acid, or fumed silica) as starting materials. The effects of the additive composition and sintering temperature on the sintered density and flexural strength of the cullet-loess tile bodies are investigated. The sintered density of the cullet-loess tile bodies increases with an increase in the sintering temperature as a result of the enhanced densification of pore walls through the viscous flow of a liquid phase formed from the glass frit and sintering additives. The flexural strength of the cullet-loess tile bodies increases with increases in the sintering temperature and the cullet content in the starting composition. A maximal flexural strength of 40 MPa is obtained in cullet-loess tile bodies sintered with glass frit at 800°C in air. © 2013 The Korean Ceramic Society.

Hong S.P.,Yonsei University | Park H.,Dongnam Health College | Kwon J.-S.,Florida International University | Yoo E.,Cheongju University
NeuroRehabilitation | Year: 2014

Background: Eccentric viewing training can be successfully applied in the clinical setting based on positive evidence. Nonetheless, published research should be integrated to provide a conclusive perspective of the efficacy of eccentric viewing training. Objective: Meta-analysis was conducted to examine effectiveness of eccentric viewing training on daily visual activities for individuals with age-related macular degeneration (AMD). Methods: The papers used in this study were located through PubMed, Ovid, ProQuest, EBSCOhost, RISS, and KMbase on studies published between January, 1990 and December, 2012. The keywords for searching were 'age-related macular degeneration' and 'eccentric viewing', 'eccentric fixation', 'peripheral vision' or 'preferred retinal loci'. The effect sizes were calculated using Comprehensive Meta-Analysis 2.0 and interpreted according to Cohen's criteria. Results: A total of 258 studies were found, among which five papers suited the main selection criteria for final analysis. The entire effect size was 0.660 (95% CI, 0.232 ~ 1.088), indicating a moderate effect size of the eccentric viewing training for individuals with AMD in their daily visual activities (p < 0.05). Conclusions: The results of this study demonstrated the clinical effectiveness of eccentric viewing training for individuals with AMD. This result should be interpreted cautiously, though, given the possibility of publication bias. © 2014 - IOS Press and the authors. All rights reserved.

Lee J.,Ajou University | Yoo J.-K.,Ajou University | Sohn H.-J.,Ajou University | Kang H.-K.,Ajou University | And 3 more authors.
Parasitology Research | Year: 2015

The free-living amoeba, Naegleria fowleri, causes a fatal disease called primary amoebic meningoencephalitis (PAM) in humans and experimental animals. Of the pathogenic mechanism of N. fowleri concerning host tissue invasion, the adherence of amoeba to hose cells is the most important. We previously cloned the nfa1 gene from N. fowleri. The protein displayed immunolocalization in the pseudopodia, especially the food-cups structure, and was related to the contact-dependent mechanism of the amoebic pathogenicity in N. fowleri infection. The cholera toxin B subunit (CTB) and Escherichia coli heat-labile enterotoxin B subunit (LTB) have been used as potent mucosal adjuvants via the parenteral route of immunization in most cases. In this study, to examine the effect of protective immunity of the Nfa1 protein for N. fowleri infection with enhancement by CTB or LTB adjuvants, intranasally immunized BALB/c mice were infected with N. fowleri trophozoites for the development of PAM. The mean time to death of mice immunized with the Nfa1 protein using LTB or CTB adjuvant was prolonged by 5 or 8 days in comparison with that of the control mice. In particular, the survival rate of mice immunized with Nfa1 plus CTB was 100 % during the experimental period. The serum IgG levels were significantly increased in mice immunized with Nfa1 protein plus CTB or LTB adjuvants. These results suggest that the Nfa1 protein, with CTB or LTB adjuvants, induces strong protective immunity in mice with PAM due to N. fowleri infection. © 2015, Springer-Verlag Berlin Heidelberg.

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