Los Angeles, CA, United States
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Patent
California Institute of Technology, University of Southern California and Doheny Eye Institute | Date: 2016-09-09

An implantable medical device is described. The implantable medical device includes a small molecule generator, a small molecule diffusor, and a cannula that connects the two. The small molecule generator includes an electrolyte reservoir and a set of electrodes. A first portion of the electrolyte reservoir is impermeable to a predetermined class of small molecules. A second portion of the electrolyte reservoir is permeable to the small molecules. The set of electrodes is disposed inside the electrolyte reservoir and is configured to facilitate electrolysis of the small molecules based on an electric power application to the set of electrodes and on presence of electrolyte inside the electrolyte reservoir. At least a portion of the small molecule diffusor is permeable to the small molecules.


Patent
Doheny Eye Institute | Date: 2016-08-26

In accordance with one aspect of the present invention, an optical coherence tomography instrument comprises an eyepiece for receiving at least one eye of a user is provided; a light source that outputs light that is directed through the eyepiece into the users eye; an interferometer configured to produce optical interference using light reflected from the users eye; an optical detector disposed so as to detect said optical interference; and electronics coupled to the detector. The electronics can be configured to perform a risk assessment analysis based on optical coherence tomography measurements obtained using the interferometer. An output device can be electrically coupled to the electronics, and may be configured to output the risk assessment to the user through the output device. The optical coherence tomography instrument can be self-administered, and the eyepiece can be a monocular system or a binocular system.


Patent
Doheny Eye Institute | Date: 2016-10-03

A surgical apparatus for use by a surgeon can include a tray and a plurality of surgical instruments. The tray can have a plurality of structures located on an upper side of the tray for receiving the plurality of surgical instruments. The tray can receive a separate control unit. The tray can also have a fluid reservoir receiver for receiving a bottle or container of fluid, such as balanced salt solution. The fluid reservoir receiver can include one or more features, including, a spike, an air vent, and a light. A separate container can be used to place the bottle or container of fluid into the fluid reservoir receiver on the tray. This separate container can include a collapsible section.


Patent
Doheny Eye Institute | Date: 2017-04-05

Surgical systems including a surgical tray unit including a portable surgical tray for housing a processing unit, a plurality of instruments connected to the portable surgical tray and operably coupled to the processing unit. A user input device positioned on at least one of the plurality of instruments. The user input device is operably coupled to the processing unit. The user input device is configured to receive a user input for controlling an operating parameter of one or more of the plurality of instruments. The processing unit is configured to receive user input through the user input device and transmit an operating command to the one or more of the plurality of instruments. The portable surgical tray and the plurality of instruments are sterilized and prepackaged in a single package.


Patent
Doheny Eye Institute | Date: 2017-04-19

There is provided a handheld surgical instrument comprising: a distal end for performing a surgical function; a body portion connected to the distal end and forming a housing; a processor contained within the housing; user controls formed on the housing and connected to the processor. The processor and user controls control the surgical function of the handheld surgical instrument and control a function of at least one other device associated with a surgery being performed. A surgical tray is also provided.


Patent
Doheny Eye Institute | Date: 2016-12-16

A sterile surgical tray includes structure for receiving a plurality of surgical instruments. The sterile surgical tray also may include electrical input and output connectors attached to tray.


In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the users or subjects eye, an interferometer configured to produce optical interference using light reflected from the users/subjects eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and/or structural ophthalmic tests and output the test data


Patent
Doheny Eye Institute | Date: 2017-05-03

A surgical apparatus for use by a surgeon can include a tray (10) and a plurality of surgical instruments. The tray can have a plurality of structures (18) located on an upper side of the tray for receiving the plurality of surgical instruments. The tray can receive a separate control unit ( 60). The tray can also have a fluid reservoir receiver (44) for receiving a bottle or container of fluid, such as balanced salt solution. The fluid reservoir receiver can include one or more features, including, a spike (80), an air vent (84), and a light (88). A separate container (110) can be used to place the bottle or container of fluid into the fluid reservoir receiver on the tray. This separate container can include a collapsible section (130).


Patent
University of Southern California and Doheny Eye Institute | Date: 2016-01-22

Disclosed herein are generally to methods and systems that facilitate imaging of cells on a substrate and more particularly to pre-implantation (in vitro) and post-implantation (in vivo) imaging of cell-seeded substrates implanted in target tissues in the context of stem cell therapy.


Patent
Doheny Eye Institute | Date: 2016-08-10

An optical coherence tomography instrument is disclosed. The instrument comprises an eyepiece for receiving at least one eye of a user, at least one target display visible through said eyepiece, and a light source that outputs light that is directed through the eyepiece to the users eye. The instrument further comprises an interferometer configured to produce optical interference using light reflected from the users eye, an optical detector disposed so as to detect said optical interference, and electronics coupled to the target display and said detector. The electronics are configured to provide an output based on optical coherence tomography measurements obtained using said interferometer, and to produce features on said target display of varying size and receive user responses to test a users visual acuity.

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