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Navi Mumbai, India

Sarwade S.S.,Dnyanopasak Science College | Jadhav W.N.,Dnyanopasak Science College | Khade B.C.,Dnyanopasak Science College | Arbad B.R.,Dr. Babasaheb Ambedkar Marathwada University
International Journal of ChemTech Research | Year: 2014

Sulfadoxine complexes of Mn(II), Co(II), Ni(II) and Cu(II) metal chlorides were synthesized and characterized by elemental analysis, molar conductivity, magnetic susceptibility measurement, Infrared (IR)and Ultraviolet (UV) spectroscopy and antimicrobial activity. Some physical parameters were obtained using molar conductance measurement and melting point determination. Based on the analytical and spectroscopic data, the complexes were proposed to havethe formula ML2Cl2. (L = Sulfadoxine).The spectroscopic data propose that sulfadoxine co-ordinated through (N-H) and (O=S=O) making it a bidentate ligand. Ligand and metal complexes are screened for their antibacterial activity. Source

El-Sayed H.S.,Dnyanopasak Science College | Salama H.H.,Dnyanopasak Science College | El-Sayed S.M.,Dnyanopasak Science College
International Journal of ChemTech Research | Year: 2015

As a part of ongoing research for more effective drugs, Mn(II) complex of metoclopramide(MCP) has been successfully synthesized for the first time and shown to be a good antimicrobial agent. Metoclopramide (MCP) has been characterized well on the basis of analytical data like conductance, magnetic measurement, electronic and infrared spectrometry and thermogravimetric-differential thermal analysis, etc. From analytical data, the stoichiometry of the complex has been found to be 2:1(L:M). The antimicrobial activity of this complex tested against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Bacillus subtilis (B. subtilis) and Bacillus megaterium(B. megaterium). © 2014, Sphinx Knowledge House. All rights reserved. Source

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