Entity

Time filter

Source Type


Kokai E.,Budapest University of Technology and Economics | Nagy J.,Budapest University of Technology and Economics | Toth T.,Budapest University of Technology and Economics | Kupai J.,Budapest University of Technology and Economics | And 3 more authors.
Monatshefte fur Chemie | Year: 2016

Abstract: A new synthetic route was elaborated at our laboratory providing a convenient access to 5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-ones (diazaoxindoles), a compound family of biological relevance. Treatment of the easily available ethyl 2-(4-chloropyrimidin-5-yl)acetate derivatives with ammonia afforded the corresponding 2-(4-aminopyrimidin-5-yl)acetamides, which were finally cyclized to the target compounds. Graphical abstract: [Figure not available: see fulltext.] © 2016 Springer-Verlag Wien Source

Discover hidden collaborations