Sunnyvale, CA, United States
Sunnyvale, CA, United States

Dionex Corporation is an American company based in Sunnyvale, California. It develops, manufactures, sells, and services chromatography, ion chromatography and extraction systems for separating, isolating, and identifying the components of chemical mixtures.Dionex develops the Chromeleon brand of chromatography software. The primary function of Chromeleon is to control and obtain data from Dionex analytical instruments although the software supports instruments from other vendors. Chromeleon 7 is the latest edition of the software.The latest technology made by Dionex is the Rapid Separation LC and the polymeric HPLC columns, a type of monolithic HPLC column. Unlike the inorganic silica columns, the polymer monoliths are made of an organic polymer base. Dionex, traditionally known for its ion chromatography capabilities, has led this side of the field. Dionex first acquired a license for the polymeric monolith technology in the 1990s.Thermo Fisher Scientific announced its acquisition of Dionex in December 2010 for $2.1 billion to develop the water sector-analysis in China. Wikipedia.

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Patent
Dionex Corporation | Date: 2017-01-30

A method of making an ion exchange foam is described. The method includes forming an aqueous phase by suspending an ion exchange resin in an aqueous solvent. An organic phase is formed by mixing at least a divinylbenzene, a monomer, and a surfactant. The formed aqueous phase is mixed with the formed organic phase to form an emulsion. The emulsion is polymerized to form the ion exchange foam. The ion exchange foam can be used with a plurality of sample vials in an autosampler.


An ion-exchange composition suitable for use in ion exchange chromatography, comprising neutral vinyl polymer support particles irreversibly bound to a dispersant having ionizable sites which are un-ionized at a neutral pH and which are ionized under highly acidic or highly basic conditions, and fine layering particles functionalized with ionexchanging sites on the surfaces thereof. A portion of the ionizable sites are ionized and bound electrostatically to a portion of the fine layering particles ion-exchanging sites, producing a support particle-dispersant-fine layering particle complex.


Patent
Dionex Corporation and Thermo Hypersil Keystone LLC | Date: 2017-04-05

A method of packing a chromatography column, including: dispersing chromatographic media particles in a slurry solution to form a slurry, filling a chromatography column with the chromatographic media particles by introducing the slurry to the column and applying a pressure to pack the chromatographic media particles in the chromatography column. The slurry solution is preferably aqueous based slurry solution. The pressure is preferably applied and held substantially constant for a first period at a first pressure and is applied and held substantially constant for a second period, following the first period, at a second pressure higher than the first pressure.


A system reduces unwanted noise due to pump movement. The system includes a pump including a non-conductive piston extending into a pumping chamber for pumping the sample fluid along an analysis fluid path, a wash chamber, and a seal fluidly separating the pumping chamber from the wash chamber. The system also includes a wash path supplying a wash fluid from a wash reservoir to the wash chamber, an electrical conductor electrically connecting the analysis fluid path to the wash fluid path, and a ground conductor electrically connecting the electrical conductor to ground via a resistor. The electrical conductors and resistor combination between the chambers reduces unwanted noise in the conductivity detector due voltage potentials between the eluent and wash chambers created as the piston moves between the chambers.


Patent
Dionex Corporation | Date: 2017-08-16

Systems and methods for concentrating an analyte preparatory to analysis thereof include processing the effluent of an analyte concentrator to produce an eluent for eluting an analyte retained in the same or separate concentrator, and systems implementing the same. The analyte concentrator system connects the effluent outlet of an analyte concentrator column to an eluent generation module such that the substantially analyte-free effluent discharged from the analyte concentrator column passes fluidly into the eluent generation module. Eluent generated from the substantially analyte-free effluent in the eluent generation module is likewise substantially free of the analyte. The systems and methods can minimize and/or (substantially) eliminate background signal during analysis of the concentrated analyte.


Patent
The University Of Texas System and Dionex Corporation | Date: 2017-01-25

An electrodialytic buffer generator is described. The buffer generator may include a central buffer-generating channel having an inlet and outlet, a second chamber, and a third chamber. The buffer-generating channel, the second chamber, and the third chamber may each include an electrode. The buffer generator may also include a first ion exchange barrier and a second ion exchange barrier. The first ion exchange barrier can be disposed between the second chamber and the buffer-generating channel. The second ion exchange barrier can be disposed between the third chamber and the buffer-generating channel.


Patent
Dionex Corporation | Date: 2017-06-14

A multi-lumen mixing device is described. The multi-lumen mixing device includes a mixer body having an inlet portion and an outlet portion. The multi-lumen mixing device also includes an array of capillary channels within the mixer body, in which each capillary channel has approximately a same length. An inlet for each of the capillaries is proximate to the inlet portion and an outlet for each of the capillaries is proximate to the outlet portion. The array of capillary channels has at least three different cross-sectional areas.


Patent
Dionex Corporation | Date: 2017-06-14

An electrolytic method for suppressing liquid eluent containing previously separated sample analyte anions, counterions to the sample anions, and non-sample anions suppressible to weak acids in an electrolytic device comprising a housing defining at least a sample stream flow channel and an ion receiving flow-through channel separated by an ion exchange barrier. The sample stream flow channel includes an upstream channel portion and a downstream channel portion. A first current is applied across the upstream channel portion for substantially completely suppression. A second current is applied across the downstream channel portion at a magnitude of less than 10% of the magnitude of the first current.


Patent
Dionex Corporation | Date: 2016-09-08

A method of extracting an analyte from a sample is described where the sample includes water. The sample and polymeric drying agent are added to a container. The polymeric drying agent includes a cationic monomer, an anionic monomer, and a crosslinker. The polymeric drying agent is configured to sorb water from the sample.


An automated method of calibrating a chromatography system and analyzing a sample is described. The method includes forming diluted standard solutions that are injected into a chromatography column. The detected peaks can be identified based on a first predetermined calibration ratio associated with the standard solution. Once the chromatography system is calibrated, samples can be chromatographically analyzed where the measured peaks are identified and quantified in an automated manner.

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