Gastroenterology & Digestive Endoscopy Unit

San Donato Milanese, Italy

Gastroenterology & Digestive Endoscopy Unit

San Donato Milanese, Italy

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PubMed | Klinik fur Gastroenterologie GI Onkologie, St Barbara Hospital, Gastroenterology & Digestive Endoscopy Unit, Royal Hallamshire Hospital and 3 more.
Type: | Journal: Gastrointestinal endoscopy | Year: 2016

The first small-bowel video-capsule endoscopy (VCE) with 360 panoramic view has been developed recently. This new capsule has wire-free technology, 4 high-frame-rate cameras, and a long-lasting battery life. The aim of the present study was to assess the performance and safety profile of the 360 panoramic-view capsule in a large series of patients from a multicenter clinical practice setting.Consecutive patients undergoing a 360 panoramic-view capsule procedure in 7 European Institutions between January 2011 and November 2015 were included. Both technical (ie, technical failures, completion rate) and clinical (ie, indication, findings, retention rate) data were collected by means of a structured questionnaire. VCE findings were classified according to the likelihood of explaining the reason for referral: P0, low; P1, intermediate; P2, high.Of the 172 patients (94 men; median age, 68 years; interquartile range, 53-75), 142 underwent VCE for obscure (32 overt, 110 occult) GI bleeding (OGIB), and 28 for suspected (17) or established (2) Crohns disease (CD). Overall, 560 findings were detected; 252 were classified as P2. The overall diagnostic yield was 40.1%; 42.2% and 30.0% in patients with OGIB and CD, respectively. The rate of complete enteroscopy was 90.2%. All patients but one, who experienced capsule retention (1/172, 0.6%), excreted and retrieved the capsule. VCE failure occurred in 4 of 172 (2.3%) patients because of technical problems.This multicenter study, conducted in the clinical practice setting and based on a large consecutive series of patients, showed that the diagnostic yield and safety profile of the 360 panoramic-view capsule are similar to those of forward-view VCEs.

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