Wang L.,University of Sichuan |
Wang L.,DiAo Co. |
Zhang B.,DiAo Co. |
Ji J.,DiAo Co. |
And 7 more authors.
Synthetic Communications | Year: 2010
A series of new 2-cyanopyrrolidine derivatives with constrained imidazolidin ring were synthesized, Their structures were confirmed by 1H NMR spectroscopy and/or mass spectrometry, and their activities were evaluated in vitro. They were proven to possess submicromolar inhibitory activities against dipeptidyl peptidase IV. © 2009 Taylor & Francis Group, LLC.