Trombo-embolic complications in Influenza A(H1N1)2009: A forgotten and fatal danger, also in so-called "mild" flu? [Trombo-embolische verwikkelingen bij influenza A(H1N1)2009: Een vergeten en fataal gevaar, ook bij "milde" griep?]
Coorevits L.,Laboratorium Voor Microbiologie |
Demuynck H.,Dienst Hematologie |
Boone E.,Laboratorium Voor Moleculaire Diagnostiek |
Roelens J.,Dienst Anatomopathologie |
Surmont I.,Laboratorium Voor Microbiologie
Tijdschrift voor Geneeskunde | Year: 2011
A 61-year-old man in remission from a multiple myeloma followed by plasma cell leukaemia, was admitted with a fatal infection due to the Influenza A(H1N1)2009 virus, detected by a widely accepted molecular technique. Autopsy revealed disseminated trombo-embolic processes to be the cause of death. Most physicians seem to be quite unfamiliar with this complication of influenza, although the first descriptions in the literature have been published decades ago. It is also obvious that the current and much more reliable - molecular - techniques to diagnose influenza may lead to new insights and revisions of its epidemiology, clinical entities and complications.