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Cambridge, MA, United States

Vella S.J.,Harvard University | Beattie P.,Diagnostics for All Inc. | Cademartiri R.,Harvard University | Laromaine A.,Harvard University | And 4 more authors.
Analytical Chemistry | Year: 2012

This paper describes a paper-based microfluidic device that measures two enzymatic markers of liver function (alkaline phosphatase, ALP, and aspartate aminotransferase, AST) and total serum protein. A device consists of four components: (i) a top plastic sheet, (ii) a filter membrane, (iii) a patterned paper chip containing the reagents necessary for analysis, and (iv) a bottom plastic sheet. The device performs both the sample preparation (separating blood plasma from erythrocytes) and the assays; it also enables both qualitative and quantitative analysis of data. The data obtained from the paper-microfluidic devices show standard deviations in calibration runs and "spiked" standards that are acceptable for routine clinical use. This device illustrates a type of test useable for a range of assays in resource-poor settings. © 2012 American Chemical Society. Source


Dfa

Trademark
Diagnostics For All Inc. | Date: 2010-01-22

reagent bearing non-medical test strips for use in determining the quality of the composition of water, milk and soil; chemical test kits for use in determining the quality of the composition of water, milk and soil for laboratory or research use. medical diagnostic test strips for use in measuring analyte levels in body fluids. kits comprising lancets and test strips for use in the accessing and measuring analyte levels in body fluids of humans and animals.


Patent
Diagnostics For All Inc. | Date: 2012-11-02

The invention provides molecular diagnostic test devices and methods for using such diagnostic test devices to detect analytes of biological significance in a patient. The diagnostic test devices are particularly useful for detecting a polynucleotide analyte in a sample obtained from a patient. Further, the diagnostic test devices are inexpensive, disposable, easy to use, and are useful at the point of care.


Trademark
Diagnostics For All Inc. | Date: 2013-01-01

Medical diagnostic test strips for use in measuring analyte levels in body fluids. Kits comprising lancets and test strips for use in the accessing and measuring analyte levels in body fluids of humans and animals.


Patent
Diagnostics For All Inc. | Date: 2012-09-27

Described herein are disposable paper-based assay devices for detection and quantitation of analytes in liquid clinical samples, e.g., blood or urine. The devices may be particularly suitable for use in regions of the world where health care infrastructure is absent. The test devices are versatile in that they can be adapted to detect a variety of analytes. The devices are also easy to use and interpret. Typically, all that is needed to conduct an assay is to apply a drop of sample to the indicated location on the device. The devices are typically colorimetric and readable with the naked eye.

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