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Sarker R.,DH Technology | Bandyopadhyay S.,Indian Statistical Institute | Maulik U.,Jadavpur University
Current Bioinformatics | Year: 2011

MicroRNAs (miRNAs) are a recently identified class of cellular non-coding RNAs that regulates protein expression and growth of a biological system during different stages of life. The active, mature miRNAs are 17-24 bases long, single-stranded RNA molecules expressed in both eukaryotic and prokaryotic cells and are known to affect the translation or stability of target messenger RNAs (mRNAs). Each miRNA is believed to regulate multiple genes and it is believed that greater than one third of all human genes may be regulated by miRNA molecules. Here in this review we try to focus on the role of these tiny molecules at different aspects of bioprocesses, prediction of miRNAs and their targets from a bioinformatics point of view. © 2011 Bentham Science Publishers Ltd.

Sarker R.,DH Technology | Bandyopadhyay S.,Indian Statistical Institute | Maulik U.,Jadavpur University
International Journal of Bio-Science and Bio-Technology | Year: 2011

Here we report on the development of an Integrated Bioinformatics Toolkit (InBit) that is application-based software, integrating various bioinformatics programs for general purpose biological data analysis like gene prediction, gene analysis, protein analysis, sequence alignment, etc. InBit will enable the biologists to use the various programs for their research purpose without being bothered with their various technical aspects. It will also help graduate students and those who are newly using bioinformatics tools. Though the individual software that is integrated in InBit are available on the web and are quite user-friendly, they often become difficult to use when the size of the data set becomes quite large. In these cases, it becomes necessary to use standalone versions of many of this software, but this requires some prior knowledge of UNIX operating system. InBit merges the standalone properties of the software in a user-friendly menu-driven environment. It is open-ended UNIX/LINUX based software that can be extended by the user if so desired. Its hardware requirements are also very basic, requiring a optimum of 1GB RAM for efficient performance.

Sarker R.,DH Technology | Maulik U.,Jadavpur University
2012 National Conference on Computing and Communication Systems, NCCCS 2012 - Proceeding | Year: 2012

MicroRNAs (MiRNA's) are ∼22nt long; one of the types of non-coding RNA having an important role in the control of the gene regulation, either by termination of the translation procedure or sometimes activating the gene actively or passively. Host-Parasite relationship largely depends on the gene regulatory network as the parasite has to survive in the host cell against the immune response of the host. So miRNA may have an important role in the host parasite relationship. The malarial parasite needs to survive in the human host cell during its life cycle. As it is well known to us today that the gene regulatory network is largely controlled by the non coding miRNA, here we are interested to find out potential miRNA in the parasite genome computationally. We have identified few putative miRNA genes in the chromosome 1 & 2 of Plasmodium vivax which need to be validated by experimental procedures. © 2012 IEEE.

Lee J.S.,DH Technology | Kim M.S.,Seoul National University
International Journal of Refrigeration | Year: 2014

Environmental issues such as stratospheric ozone depletion and global warming have been the primary motivations for recent research in the air-conditioning and refrigeration fields. The CO2 air-conditioning system forms a transcritical cycle which shows slightly degraded performance compared to the conventional system. To overcome this disadvantage, a cycle adopting an ejector is suggested. Experimental results of a CO2 air-conditioning system using an ejector were compared for various outdoor temperatures and inverter frequencies. The COPs of an air-conditioning system using an ejector and conventional system were calculated and compared based on the pressures and temperatures of experiments. The cooling capacity and COP in the air-conditioning system using an ejector are higher than those in the conventional system at an entrainment ratio greater than 0.76. In addition, better performance is shown at entrainment ratio greater than a certain value in other test conditions. © 2013 Elsevier Ltd and IIR. All rights reserved.

A container electronic seal device and a method of operating the container electronic seal device are provided. The container electronic seal device is installed on a door locking rod and a lock handle provided in a container door. The apparatus includes a body unit, a locking arm unit, and an electronic parts unit. The body unit is disposed around part of the door locking rod and part of the lock handle, and is provided with a through hole, a guide opening, and an access port. The locking arm unit rotates and fastens the lock handle inserted into the guide opening of the body unit. The electronic parts unit selectively performs locking and unlocking depending on whether a security authentication file of the external memory is normal and monitors illegitimate opening. The container electronic seal device is selectively locked and unlocked using the external memory storing a security authentication file.

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