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Greencastle, IN, United States

DePauw University in Greencastle, Indiana, US, is a private, national liberal arts college and School of Music with an enrollment of approximately 2,400 students. The school has a Methodist heritage and was originally known as Indiana Asbury University. DePauw is a member of both the Great Lakes Colleges Association and the North Coast Athletic Conference. The Society of Professional Journalists was founded at DePauw. DePauw is home to both the first modern-day sorority and the two longest continuously-running fraternities in the world. Wikipedia.

Schneider H.,DePauw University
Neuromethods | Year: 2011

Adult zebrafish (Danio rerio) are territorial, show aggressive behavior, and establish dominant-subordinate hierarchies. Here, a protocol for a standard opponent setup is described, which enables the identification, characterization, and quantification of agonistic activities of zebrafish. Following a period of social isolation, zebrafish are placed into an observation tank, engage in an agonistic encounter, and establish a dominance hierarchy within 15 min. The analysis of the behavior includes quantification of activities such as lateral display, frontal display, chasing and nipping over the course of the observational period with the help of The Observer® program. As a result, an event plot and a histogram are generated, which show the dynamics of agonistic activities. The described method can be used to quantify the effects of drug treatment or to identify modified activity patterns in mutant zebrafish. © 2011 Springer Science+Business Media, LLC. Source

Schmit V.L.,University of Wyoming | Martoglio R.,DePauw University | Carron K.T.,University of Wyoming
Analytical Chemistry | Year: 2012

We describe a novel sandwich assay based on surface enhanced Raman scattering (SERS) comprised of buoyant silica microspheres coated with antibodies against the β subunit of the cholera toxin (CT), and gold nanoparticles tagged with a Raman reporter, shelled with silica and coated with antibodies against the β subunit of the CT. Together these components couple to form a sandwich which, after incubation, floats on the surface of the sample. The buoyant silica microparticle/nanoparticle reporter combination has been coined a lab on a bubble (LoB). LoB materials may provide a platform for rapid detection of antigen in solution and offers advantages over lateral flow or magnetic pull-down assays. The Raman reporter provides a unique and intense signal to indicate a positive analysis. Our limit of detection for the β subunit of the CT in a buffer based system is 1100 ng. © 2012 American Chemical Society. Source

Gayazova O.,DePauw University
International Journal of Marine and Coastal Law | Year: 2012

Abstract That the geographic North Pole is the Arctic Schelling point, is implicit in the Russian submission to the Commission on the Limits of the Continental Shelf. I assess this premise vis-à-vis three other approaches to the outer continental shelf delimitation in the Arctic Ocean-the median-line method; a joint submission; and an international zone around the North Pole-and show that both the premise and the alternatives have limitations. Then I explain how an agreement between the Arctic Ocean states (the A5) to establish a seabed nature reserve north of 88°20'N and within 100 nm from the 2,500-meter isobath overcomes those limitations and what positive direct and indirect effects may come from it. © 2012 Koninklijke Brill NV, Leiden. Source

Roberts M.E.,DePauw University | Goldstone R.L.,Indiana University Bloomington
PLoS ONE | Year: 2011

Many real world situations (potluck dinners, academic departments, sports teams, corporate divisions, committees, seminar classes, etc.) involve actors adjusting their contributions in order to achieve a mutually satisfactory group goal, a win-win result. However, the majority of human group research has involved situations where groups perform poorly because task constraints promote either individual maximization behavior or diffusion of responsibility, and even successful tasks generally involve the propagation of one correct solution through a group. Here we introduce a group task that requires complementary actions among participants in order to reach a shared goal. Without communication, group members submit numbers in an attempt to collectively sum to a randomly selected target number. After receiving group feedback, members adjust their submitted numbers until the target number is reached. For all groups, performance improves with task experience, and group reactivity decreases over rounds. Our empirical results provide evidence for adaptive coordination in human groups, and as the coordination costs increase with group size, large groups adapt through spontaneous role differentiation and self-consistency among members. We suggest several agent-based models with different rules for agent reactions, and we show that the empirical results are best fit by a flexible, adaptive agent strategy in which agents decrease their reactions when the group feedback changes. The task offers a simple experimental platform for studying the general problem of group coordination while maximizing group returns, and we distinguish the task from several games in behavioral game theory. © 2011 Roberts, Goldstone. Source

Pickerill M.L.,DePauw University | Harter R.A.,Texas State University
Journal of Athletic Training | Year: 2011

Context: A lack of published comparisons between measures from commercially available computerized posturography devices and the outcome measures used to define the limits of stability (LOS) makes meaningful interpretation of dynamic postural stability measures difficult. Objectives: To compare postural stability measures between and within devices to establish concurrent and construct validity and to determine test-retest reliability for LOS measures generated by the NeuroCom Smart Balance Master and the Biodex Balance System. Design: Cross-sectional study. Setting: Controlled research laboratory. Patients or Other Participants: A total of 23 healthy participants with no vestibular or visual disabilities or lower limb impairments. Intervention(s) The LOS were assessed during 2 laboratory test sessions 1 week apart. Main Outcome Measure(s): Three NeuroCom LOS variables (directional control, endpoint excursion, and movement velocity) and 2 Biodex LOS variables (directional control, test duration). Results: Test-retest reliability ranged from high to low across the 5 LOS measures (intraclass correlation coefficient [2,k] = 0.82 to 0.48). Pearson correlations revealed 4 significant relationships (P < .05) between and within the 2 computerized posturography devices (r = 0.42 to -0.65). Conclusions: Based on the wide range of intraclass correlation values we observed for the NeuroCom measures, clinicians and researchers alike should establish the reliability of LOS testing for their own clinics and laboratories. The low to moderate reliability outcomes observed for the Biodex measures were not of sufficient magnitude for us to recommend using the LOS measures from this system as the gold standard. The moderate Pearson interclass correlations we observed suggest that the Biodex and NeuroCom postural stability systems provided unique information. In this study of healthy participants, the concurrent and construct validity of the Biodex and NeuroCom LOS tests were not definitively established. We recommend that this study be repeated with a clinical population to further explore the matter. © by the National Athletic Trainers' Association. Source

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