Suribabu C.R.,SASTRA University |
Neelakantan T.R.,SASTRA University |
Sivakumar P.,Deemed University
ISH Journal of Hydraulic Engineering | Year: 2017
Water distribution system supplies water to the consumers as per the designed condition if requirement of water matches with designed level. It seldom matches the designed condition during operation scenario. Uncertainty of the demand, failure of components, diversion of water, aging of pipeline, permanent increase in the demand at certain supply node, fire demand etc. creates deficit in supply. In such situations, it is important to assess actual flow that can be delivered from nodes so that the authority concerned can take up alternate steps to tackle the situation immediately. Though there are several methods available to analyze pipe networks under pressure-deficient conditions, researchers evolve new approaches or improve existing approaches that can be implemented easily with existing software. This paper proposes an improved method for pressure-driven analysis to minimize the number of addition or deletion of complementing reservoirs in complementary reservoir solution approach. Main logic of the improved method is that no supply from a node is possible if the pressure drop at a node exceeds the difference in hydraulic gradient of source and maximum pressure drop node. The proposed method is applied to three benchmark networks and results of the study show that the improved method simplifies the analysis process by reducing number of addition of complementing reservoirs. © 2017 Indian Society for Hydraulics
Singh P.,Deemed University
International Journal of Information and Decision Sciences | Year: 2014
Women empowerment calls for creating a political, economic and social environment which enables their equal access to control over the means that are critical for leading socio-economical productive and healthy lives. This study investigates the important parameters responsible for women empowerment. The research utilises a new research methodology multi-criteria futuristic fuzzy decision hierarchy methodology which combines fuzzy logic and analytical hierarchy process (AHP) due to the multiplicity of criteria. Women from different ethnic, religion and residential backgrounds were surveyed. The problem considers six dimensions and three categories for each dimension. It was found that for household category, the parameters psychological and social-culture; for community category, the parameters economic and social-culture; and for broader arena, the parameters social-culture and legal were treated important. Copyright © 2014 Inderscience Enterprises Ltd.
Deo V.,Deemed University |
Bhongade M.L.,Deemed University
Dentistry Today | Year: 2010
There is no doubt that plaque bacteria are necessary to initiate disease and drive the chronic inflammatory response in the periodontal tissues. At the same time, there is strong evidence that destructive processes occurring as part of the host inflammatory response are responsible for the majority of the hard- and soft-tissue breakdown leading to the clinical signs of periodontitis. The characteristic clinical signs of chronic periodontitis occur mainly as a result of activation of host-derived immune and inflammatory defense mechanism. IL-1 and TNF induce expression of other mediators that amplify the inflammatory response, such as prostaglandins, and lead to production of lytic enzymes and stimulate the production of chemokines. Investigations on the soluble protein delivery of antagonists to IL-1 and TNF in animal models have shown promising results. Collectively, the clinical, radiographic, and biochemical findings of these experiments show that IL-1 and TNF-α antagonists block the progression of the inflammatory cell infiltrate towards the alveolar crest and the recruitment of osteoclasts, and prevent the loss of periodontal attachment and alveolar bone. Further, the findings of Martuscelli, et al4I indicate that subcutaneous injection of rhIL-11 was able to alter periodontal disease progression measured by changes in attachment level and radiographic bone height. However, a harsh enzymatic environment in periodontal lesions may destroy the soluble cytokine antagonists prior to their peak activity, which may necessitate more frequent administration of the active agents to the defects. Thus, gene transfer of TNF receptor antagonists and IL-lra may offer a more efficient mode of delivery of disease controlling agents to the periodontal structures. Periodontal treatment through the ages has focused on the reduction of bacterial infection by mechanical removal of infectious agents (ie, SRP). Attempts at elimination of infectious agents often do not represent a definitive therapy in periodontitis, necessitating the administration of more sophisticated biological treatment modalities. A thorough understanding of the host inflammatory response in periodontal pathogenesis presents the opportunity for exploiting new treatment strategies for periodontitis by means of host response modulation. The rationale behind this approach is to aid the host in its fight against infectious agents by supplementing the natural inherent defense mechanism or to modify its responses by changing the course of inflammatory systems. Therefore, pharmaceutical inhibition of host response pathways that mimic endogenous anti-inflammatory mechanisms may prove to be an effective strategy for treating periodontal diseases. This would require the development of polypharmaceutical approaches controlling all pathways associated with inflammation and tissue destruction. Current research has focused on the use of SDD as a treatment modality, and SDD is the only systemically used host modulatory drug approved by the United States Food and Drug Administration.
Maheswari N.,Deemed University |
Muralidharan G.,Deemed University
Dalton Transactions | Year: 2016
Cerium oxide (CeO2) has emerged as a new and promising pseudocapacitive material due to its prominent valance states and extensive applications in various fields. In the present study, hexagonal CeO2 nanostructures have been prepared via the hydrothermal method employing cationic surfactant cetyl trimethyl ammonium bromide (CTAB). CTAB ensures a slow rate of hydrolysis to form small sized CeO2 nanostructures. The role of calcination temperature on the morphological, structural, electrochemical properties and cyclic stability has been assessed for supercapacitor applications. The mesoscopic hexagonal architecture endows the CeO2 with not only a higher specific capacity, but also with an excellent rate capability and cyclability. When the charge/discharge current density is increased from 2 to 10 A g-1 the reversible charge capacity decreased from 927 F g-1 to 475 F g-1 while 100% capacity retention at a high current density of 20 A g-1 even after 1500 cycles could be achieved. Furthermore, the asymmetric supercapacitor based on CeO2 exhibited a significantly higher energy density of 45.6 W h kg-1 at a power density of 187.5 W kg-1 with good cyclic stability. The electrochemical richness of the CeO2 nanostructure makes it a suitable electrode material for supercapacitor applications. © 2016 The Royal Society of Chemistry.
Srinivasan K.,Alagappa University |
Kayalvizhi K.,Alagappa University |
Sivakumar K.,Deemed University |
Stalin T.,Alagappa University
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy | Year: 2011
The photophysical, electrochemical and photoprototropic behaviors of diphenylamine (DPA) in aqueous β-cyclodextrin (β-CD) solution have been investigated using absorption spectroscopy and cyclic voltammetric techniques. Absorption of the neutral and cationic form of DPA is enhanced due to the formation of a 1:1 complex with β-CD. The formation of this complex has been confirmed by Benesi-Hildebrand plot and docking studies by RasMol tool methods. The solid complex of β-CD with DPA is investigated by FT-IR, XRD and AFM methods. The thermodynamic parameters (ΔG, ΔH and ΔS) of inclusion process are also determined. The pKa values of neutral-monocation equilibria have been determined with absorption (conjugate acid-base) titrations. A mechanism is proposed to explain the inclusion process. © 2010 Elsevier B.V. All rights reserved.
Deo V.,Deemed University
The journal of contemporary dental practice | Year: 2010
AIM: Diabetic patients have more severe periodontal destruction, but periodontal therapy can improve metabolic control. Recently, interest has focused on the use of subantimicrobial dose doxycycline (SDD) as a treatment paradigm. Therefore, this study was undertaken to evaluate clinical efficacy of SDD with scaling and root planning (SRP) in chronic periodontitis patients with diabetes. METHODS AND MATERIALS: Twenty chronic periodontitis patients with diabetes mellitus were randomly allocated to either a test and a control group. Clinical measurements were recorded at baseline and at six months for probing pocket depth (PPD), clinical attachment level (CAL), and gingival recession (GR). After SRP, patients in the test group were instructed to take SDD 20-mg capsules twice a day while patients in the control group took a placebo twice a day. Both groups were on this regimen for a six-month period. RESULTS: A greater reduction in mean PPD was demonstrated in patients in the test group compared to the control group. The mean CAL increase observed in the test group was significantly greater (0.67 mm) than that in the control group. CONCLUSION: It can be concluded that SRP, in conjunction with the SDD therapy described, is more effective then SRP alone in terms of CAL gain and PPD reduction in diabetic patients with severe periodontal disease. CLINICAL SIGNIFICANCE: Given the widespread prevalence of both chronic periodontitis and diabetes, the proposed treatment approach will prove to be of great value and contribute significantly to the overall health of the patients.
Chavan R.S.,Deemed University
The International journal of periodontics & restorative dentistry | Year: 2013
Open flap debridement with flap repositioning may result in significant gingival recession. Patients with chronic periodontitis were treated with open flap debridement followed by placement of an acellular dermal matrix allograft (ADMA) underneath the flap to minimize the occurrence of postsurgical gingival recession. Ten patients (total, 60 teeth) with periodontal pockets in the anterior dentition underwent open flap debridement combined with ADMA. Probing pocket depth, relative attachment level, and relative gingival margin level were recorded at baseline and 6 months postsurgery. The mean probing pocket depth at baseline and 6 months was 4.4 and 1.7 mm, respectively (P < .05); the mean relative attachment level at baseline and 6 months was 12.9 and 10.7 mm, respectively (P < .05); and the mean relative gingival margin level at baseline and 6 months was 8.4 and 9.0 mm, respectively. ADMA underneath the flap when combined with open flap debridement effectively minimizes postsurgical gingival recession.
Bhagat S.K.,Deemed University
Advances in Modelling and Analysis C | Year: 2012
A generalized balancing free reduction algorithm which combines the advantages of balancing free, square root and singular perturbation approximation techniques is proposed in this paper. The proposed technique is based on the singular value decomposition of Cholesky factors of controllability and observability gramians. The merit of the proposed algorithm is, it is almost free from all the deficiencies of Moore's balanced realization and truncation and removes the necessity of using bilinear-transformation and hence the occurrence of two-fold error is avoided. The applicability of the proposed technique has been illustrated with the help of some benchmark examples and reduced models obtained produce far better results than the existing ones.
Majumder S.,Deemed University |
Devi K.J.,Deemed University |
Sarkar S.K.,Jadavpur University
IET Biometrics | Year: 2013
Tabish A.,Deemed University
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2013
Carcinoma Breast is a tumor that starts from cells of the breast tissue, either in cells that line the ducts that carry milk to the nipples (ductal carcinoma) and/or in cells that line the lobules, which are glands involved in milk production (lobular carcinoma).In 2004, Carcinoma Breast caused519,000 deaths worldwide (7% of cancer deaths); almost 1% of all death. Thefirst noticeable symptom of breast cancer is typically a lump that feels different from the rest of the breast tissue. More than 80% of breast cancer cases are discovered when the woman feels a lump. The primary risk factors that have been identified are sex, age, lack of childbearing or breastfeeding and higher hormone levels. The risk factors for them are ageing(>60 yrs), family history, inherited gene mutations, Klinefelter's syndrome, alcohol, liver disease like cirrhosis, obesity, estrogen treatment as used in prostatic carcinomas, testicular conditions like undescended testis, mumps, orchiectomy and long term exposures to higher temperature and radiation. Therefore, the present study was conceived, designed and carried out as the pioneerstudy of this arena to explore the pharmacoepidemological domain of carcinoma breast in Acharya Vinoba Bhave Rural Hospital- a tertiary health care setting of central India.